Biography
Minnie M. Sarwal M.D., Ph.D., FRCP, DCH is Professor in Residence, Department of Surgery, Division of Transplant Surgery, Co-Director of the Pancreas Kidney Transplant Program, Director of the Precision Transplant Medicine, Sarwal Lab at UCSF. Sarwal is a nationally and internationally recognized leader in the fields of renal and transplant medicine, genomics, proteomics and immunology. The Sarwal Lab supported precision and predictive diagnostic and therapeutic approaches for organ transplant recipients by discovering new treatments and investigative approaches using in vitro, CRISPR-Cas9, and animal KO models relevant to kidney disease, FSGS and transplant rejection. Sarwal was Professor of Surgery, Pediatrics and Immunology at Stanford University, Medical Director of the Pediatric Kidney Transplant Program at Lucille Packard Children's Hospital and Director of the Sarwal Lab for 16 years prior to joining UCSF in 2014.
Sarwal received her M.D. from Calcutta Medical College in India, completed her residency in the UK, and a fellowship in Pediatric Nephrology at Guy's Hospital, London, UK. She earned her Ph.D. in Molecular Genetics from Cambridge University (Christ's College) where she worked with Nobel Laureate Sydney Brenner on the synthetic mapping of human and puffer fish G proteins. Sarwal also holds a Diploma in Child Health from London, UK, and degrees from the Royal College of Physicians, UK (MRCP) and is an elected Fellow of the Royal College of Physicians, UK in recognition of her outstanding contributions to the field of medicine. Sarwal is a member of numerous national and international societies including the ASN, IPTA, AST, TTS, and IPNA. She is Chief Editor, Frontiers in Nephrology (a nature journal), AE for Clinical Transplantation and has published in and served as AE/reviewer for many other scientific journals inclusive of the Nature Medicine, NEJM, AJT, Nature Communications, PNAS, Journal of Immunology and Journal of Experimental Medicine.
Sarwal has also been the recipient of numerous awards and distinctions, including the Order of Excellence in Scientific Research (Cambridge, UK, 2002), the Dean's Teaching Award (2005), the Junior Faculty Award from the CCIS (2003-6), recognized Key Opinion Leader in Organ Transplantation by the Transplantation Society (2007-2009), elected Senator at Large for the Stanford Faculty Senate (2005-10), Faculty Senate UCSF (2015-17), the TTS-Roche Award for Outstanding Achievement Transplantation Science (Clinical; 2010), and the Cunio Richardson NKF Award for Scientific Excellence (2012). She also serves on the FDA Science Board for her third term, and is current Chair of the NIH-SBIR review study section and is Chair of the Department of Defense, Tissue Transplantation section. She is also a successful entrepreneur scientist and a founding member of the Rosenman Institute at UCSF.
Videos
Education
La Martiniere, Calcutta, India, English Language and Literature, I.S.C.,1981
Calcutta Medical College, Calcutta, India, M.D.,1985
Diploma in Child Health (D.C.H.), London, UK, with distinction 1989
Cambridge University, U.K, Ph.D.,1995
Residency (Medicine and Surgery), Calcutta Medical College, India, 06/1986-06/1987
Senior House Officer (Pediatrics and Surgery), Calcutta Medical College, India. Advisors: Sir Keith Peters, Sir Cyril Chantler and Sydney Brenner, 06/1987-02/1988
Senior House Officer, General Pediatrics & Neonates, Good Hope Hospital, Sutton Coldfield, Birmingham, UK, 02/-07/1989
Senior House Officer, General Pediatrics & Neonates, Grantham and Kesteven Hospital, Granthan (GKGH), UK, 03/1988-02/1989
Senior House Officer, Neonatology, Leicester Royal Infirmary (LRI), Leicester, UK, 08/-11/1989
Senior House Officer, General Pediatrics & Neonates, Leicester General Hosp. (LGH), Leicester, UK, 12/89- 03/90
Registrar, Pediatric Cardiology and Cardiothoracic Surgical Unit, Groby Road Hospital, (GRH), Leicester, UK, 04/90-07/90
Senior House Officer, Pediatric Nephrology Unit, Guy's Hospital, London, UK, 08/90-10/90
Lecturer/Registrar, Pediatric Unit, Guy's Hospital, London, UK, 10/90-09/91
Lecturer/Senior Registrar, Pediatric Nephrology, Dept. of Pediatrics, Guy's Hospital, London, U.K., 10/92-07/95
Fellowship in Nephrology, Department of Pediatrics, Addenbrooke's Hospital, Cambridge, 10/91-09/92
Ph.D., Molecular Genetics Unit, Christs College, Cambridge University, 10/92-12/95
Clinical Expertise
Acute Kidney Failure
Chronic Kidney Disease
End-Stage Renal Disease
Kidney Transplant Clinical Trials
Pediatric Bone and Mineral Disorders
Pediatric Kidney Transplantation
Pediatric Transplant Nephrology
Transplant Immunology
Oxalosis
Methylmalonic acidemia
Cystinosis
Clinical Trials
- KIDney Injury in Times of COVID-19 (KIDCOV) (NCT04705766)Related Conditions: COVID-19, Acute Kidney Injury, Kidney Injury, Severe Acute Respiratory Syndrome| Start Date: | End Date:
Foreign Languages Spoken
Hindi, Punjab
Program Affiliations
UCSF Biomedical Sciences (BMS) Program
Associate Member, UCSF Liver Center
In the News
Grants and Funding
- Filling a Void of Research (FAVOR) Training for Transplant Surgeons | NIH | 2016-08-01 - 2026-07-31 | Role: Co-Principal Investigator
- Mapping Immune Responses to CMV in Renal Transplant Recipients | NIH | 2017-08-01 - 2022-07-31 | Role: Co-Principal Investigator
- CD40 autoantibody and FSGS recurrence | NIH | 2017-04-01 - 2022-03-31 | Role: Principal Investigator
- Drug Repositioning in Diabetic Nephropathy | NIH | 2016-09-01 - 2020-07-31 | Role: Principal Investigator
- Transplant injury biology and monitoring by urine proteomics | NIH | 2009-07-01 - 2016-08-31 | Role: Principal Investigator
- Urinary Proteome Monitoring for Transplant Injury | NIH | 2010-08-23 - 2015-09-19 | Role: Principal Investigator
- Gene and Cytokine Expression in Tolerance and GVHD | NIH | 2009-09-25 - 2014-08-31 | Role: Co-Principal Investigator
- A Proteomics Research Resource for Integrative Biology | NIH | 2003-09-15 - 2013-06-30 | Role: Co-Investigator
- General Clinical Research Center | NIH | 1978-12-01 - 2011-11-30 | Role: Co-Investigator
- Novel Urinary Proteomic Biomarkers for Acute Renal Transplant Rejection | NIH | 2009-06-01 - 2011-05-31 | Role: Principal Investigator
- Defining Biomarkers in Pediatric Renal Transplantation | NIH | 2004-06-01 - 2009-05-31 | Role: Principal Investigator
Research Narrative
As principal Investigator on numerous multicenter clinical trials, both industry and institutional, Sarwal has developed extensive expertise in the design and execution of clinical studies. While at Stanford, Sarwal conducted the first successful U.S. steroid avoidance trial and the first dosing safety trial for Rituximab in pediatric renal transplantation.
In 2009, Sarwal founded, Organ-i, a Stanford University spin-out to develop and commercialize her pioneering work. Organ-i leveraged 15 years of research and over $20M in NIH grants. The company's goal is to improve the clinical management of transplant patients globally by commericializing non-invasive tests to monitor and predict organ health for transplant recipients.
Sarwal is credited with the introduction of (k-SORT), a Kidney Solid Organ Rejection Test, the company's lead product, as well as a pipeline of molecular assays focused on post-transplant rejection monitoring and allograft tolerance. In June 2014. Immucor, Inc., a global leader in transfusion and transplantation diagnostics, announced the acquisition of Organ-i and retained Sarwal as a scientific advisory role to advance the Organ-i pipeline.
Research Interests
Organ diseases
Transplant immunobiology of rejection and tolerance
Genomics
Proteomics
Antibiomics
Metabolomics
GVHD
Hepatitis B, C and HIV
Research Pathways
Publications
- The Banff 2022 Kidney Meeting Work Plan: Data-driven refinement of the Banff Classification for renal allografts.| | View in PubMed
- Proteome Analysis for Inflammation Related to Acute and Convalescent Infection.| | View in PubMed
- Urine trumps the protocol biopsy for subclinical rejection surveillance.| | View in PubMed
- Transcriptional and spatial profiling of the kidney allograft unravels a central role for FcyRIII+ innate immune cells in rejection.| | View in PubMed
- Plasma proteome perturbation for CMV DNAemia in kidney transplantation.| | View in PubMed
- Perturbations in podocyte transcriptome and biological pathways induced by FSGS associated circulating factors.| | View in PubMed
- Longitudinal serum proteomics analyses identify unique and overlapping host response pathways in Lyme disease and West Nile virus infection.| | View in PubMed
- Perturbations of the T-cell immune repertoire in kidney transplant rejection.| | View in PubMed
- Pan-vaccine analysis reveals innate immune endotypes predictive of antibody responses to vaccination.| | View in PubMed
- The Immune Signatures data resource, a compendium of systems vaccinology datasets.| | View in PubMed
- Malnutrition and immune cell subsets in children undergoing kidney transplantation.| | View in PubMed
- A reference tissue atlas for the human kidney.| | View in PubMed
- Mass cytometry reveals single-cell kinetics of cytotoxic lymphocyte evolution in CMV-infected renal transplant patients.| | View in PubMed
- Through the Looking Glass: Unraveling the Stage-Shift of Acute Rejection in Renal Allografts.| | View in PubMed
- Urinary Biomarkers for Kidney Allograft Injury.| | View in PubMed
- Multiplexed droplet single-cell sequencing (Mux-Seq) of normal and transplant kidney.| | View in PubMed
- FcER1: A Novel Molecule Implicated in the Progression of Human Diabetic Kidney Disease.| | View in PubMed
- Improving Clinical Trials for Anticomplement Therapies in Complement-Mediated Glomerulopathies: Report of a Scientific Workshop Sponsored by the National Kidney Foundation.| | View in PubMed
- A large staghorn stone diagnosed and managed in an asymptomatic patient using the "Kidney Injury Test (Kit)" spot urine assay: A case report.| | View in PubMed
- The Importance of Bringing Transplantation Tolerance to the Clinic.| | View in PubMed
- A Comprehensive Urine Proteome Database Generated From Patients With Various Renal Conditions and Prostate Cancer.| | View in PubMed
- Rationale and design of the Kidney Precision Medicine Project.| | View in PubMed
- Use of the Tissue Common Rejection Module Score in Kidney Transplant as an Objective Measure of Allograft Inflammation.| | View in PubMed
- Corrigendum: Near-Single-Cell Proteomics Profiling of the Proximal Tubular and Glomerulus of the Normal Human Kidney.| | View in PubMed
- Single-Cell RNA Sequencing of Tocilizumab-Treated Peripheral Blood Mononuclear Cells as an in vitro Model of Inflammation.| | View in PubMed
- Molecular Diversity of Clinically Stable Human Kidney Allografts.| | View in PubMed
- A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project.| | View in PubMed
- Single-cell RNA sequencing of Tocilizumab-treated peripheral blood mononuclear cells as an in vitro model of inflammation.| | View in PubMed
- Impact of Sarcopenia on Simultaneous Pancreas and Kidney Transplantation Outcomes: A Retrospective Observational Cohort Study.| | View in PubMed
- Near-Single-Cell Proteomics Profiling of the Proximal Tubular and Glomerulus of the Normal Human Kidney.| | View in PubMed
- Relationship between antithymocyte globulin, T cell phenotypes, and clinical outcomes in pediatric kidney transplantation.| | View in PubMed
- Peripheral Blood RNA Sequencing Unravels a Differential Signature of Coding and Noncoding Genes by Types of Kidney Allograft Rejection.| | View in PubMed
- Clinical and Analytical Validation of a Novel Urine-Based Test for the Detection of Allograft Rejection in Renal Transplant Patients.| | View in PubMed
- Targeted Urine Metabolomics for Monitoring Renal Allograft Injury and Immunosuppression in Pediatric Patients.| | View in PubMed
- Avoidance of CNI and steroids using belatacept-Results of the Clinical Trials in Organ Transplantation 16 trial.| | View in PubMed
- A urine score for noninvasive accurate diagnosis and prediction of kidney transplant rejection.| | View in PubMed
- Use of biomarkers to improve immunosuppressive drug development and outcomes in renal organ transplantation: A meeting report.| | View in PubMed
- Long-term follow-up of beta cell replacement therapy in 10 HIV-infected patients with renal failure secondary to type 1 diabetes mellitus.| | View in PubMed
- Non-radiological assessment of kidney stones using the kidney injury test (KIT), a spot urine assay.| | View in PubMed
- Further Evidence That the Soluble Urokinase Plasminogen Activator Receptor Does Not Directly Injure Mice or Human Podocytes.| | View in PubMed
- Assessment of 19 Genes and Validation of CRM Gene Panel for Quantitative Transcriptional Analysis of Molecular Rejection and Inflammation in Archival Kidney Transplant Biopsies.| | View in PubMed
- Noninvasive Urinary Monitoring of Progression in IgA Nephropathy.| | View in PubMed
- A urinary Common Rejection Module (uCRM) score for non-invasive kidney transplant monitoring.| | View in PubMed
- A Modified Injector and Sample Acquisition Protocol Can Improve Data Quality and Reduce Inter-Instrument Variability of the Helios Mass Cytometer.| | View in PubMed
- Characterizing pre-transplant and post-transplant kidney rejection risk by B cell immune repertoire sequencing.| | View in PubMed
- A Novel Multi-Biomarker Assay for Non-Invasive Quantitative Monitoring of Kidney Injury.| | View in PubMed
- Assessment of Postdonation Outcomes in US Living Kidney Donors Using Publicly Available Data Sets.| | View in PubMed
- Call for an End to Unethical Transplant Practices: A Concerted Effort by the Transplant Community.| | View in PubMed
- Cell-Free DNA and CXCL10 Derived from Bronchoalveolar Lavage Predict Lung Transplant Survival.| | View in PubMed
- Optimizing Detection of Kidney Transplant Injury by Assessment of Donor-Derived Cell-Free DNA via Massively Multiplex PCR.| | View in PubMed
- The common rejection module in chronic rejection post lung transplantation.| | View in PubMed
- Urinary Virome Perturbations in Kidney Transplantation.| | View in PubMed
- Mechanisms and biomarkers of immune quiescence in kidney transplantation.| | View in PubMed
- Targeted Transcriptional Profiling of Kidney Transplant Biopsies.| | View in PubMed
- Corrigendum: Novel Non-Histocompatibility Antigen Mismatched Variants Improve the Ability to Predict Antibody-Mediated Rejection Risk in Kidney Transplant.| | View in PubMed
- Discovery of Immune Reactive Human Proteins by High-Density Protein Arrays and Customized Validation of Potential Biomarkers by ELISA.| | View in PubMed
- LC-SRM-Based Targeted Quantification of Urinary Protein Biomarkers.| | View in PubMed
- Optimization for Peptide Sample Preparation for Urine Peptidomics.| | View in PubMed
- Novel Non-Histocompatibility Antigen Mismatched Variants Improve the Ability to Predict Antibody-Mediated Rejection Risk in Kidney Transplant.| | View in PubMed
- Protein biomarkers in renal transplantation.| | View in PubMed
- Expression of Mitochondrial-Encoded Genes in Blood Differentiate Acute Renal Allograft Rejection.| | View in PubMed
- Polyclonal Regulatory T Cell Therapy for Control of Inflammation in Kidney Transplants.| | View in PubMed
- Transplantomics: Toward Precision Medicine in Transplantation Research.| | View in PubMed
- Retrospective evaluation of the efficacy and safety of belatacept with thymoglobulin induction and maintenance everolimus: A single-center clinical experience.| | View in PubMed
- A Comprehensive Analysis of the Current Status and Unmet Needs in Kidney Transplantation in Southeast Asia.| | View in PubMed
- Assessment of Circulating Protein Signatures for Kidney Transplantation in Pediatric Recipients.| | View in PubMed
- Molecular and Functional Noninvasive Immune Monitoring in the ESCAPE Study for Prediction of Subclinical Renal Allograft Rejection.| | View in PubMed
- Transplant genetics and genomics.| | View in PubMed
- Relationship Among Viremia/Viral Infection, Alloimmunity, and Nutritional Parameters in the First Year After Pediatric Kidney Transplantation.| | View in PubMed
- A combined biomarker and clinical panel for chronic graft versus host disease diagnosis.| | View in PubMed
- Unraveling the Role of Allo-Antibodies and Transplant Injury.| | View in PubMed
- Advances in diagnostics for transplant rejection.| | View in PubMed
- Intragraft Antiviral-Specific Gene Expression as a Distinctive Transcriptional Signature for Studies in Polyomavirus-Associated Nephropathy.| | View in PubMed
- Self-antigens and rejection: a proteomic analysis.| | View in PubMed
- Mining the human urine proteome for monitoring renal transplant injury.| | View in PubMed
- Fingerprints of transplant tolerance suggest opportunities for immunosuppression minimization.| | View in PubMed
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).| | View in PubMed
- Non-HLA Antibodies in Clinical Transplantation.| | View in PubMed
- Circulating CD40 autoantibody and suPAR synergy drives glomerular injury.| | View in PubMed
- A Computational Gene Expression Score for Predicting Immune Injury in Renal Allografts.| | View in PubMed
- Computational Models for Transplant Biomarker Discovery.| | View in PubMed
- Transcriptional Perturbations in Graft Rejection.| | View in PubMed
- Pediatric Deceased Donation-A Report of the Transplantation Society Meeting in Geneva.| | View in PubMed
- Antibody-mediated rejection in pediatric kidney transplantation: pathophysiology, diagnosis, and management.| | View in PubMed
- Tolerance associated gene expression following allogeneic hematopoietic cell transplantation.| | View in PubMed
- Perturbations in the urinary exosome in transplant rejection.| | View in PubMed
- Mapping novel immunogenic epitopes in IgA nephropathy.| | View in PubMed
- Antibody-mediated rejection in young kidney transplant recipients: the dilemma of noncompliance and insufficient immunosuppression.| | View in PubMed
- A Three-Gene Assay for Monitoring Immune Quiescence in Kidney Transplantation.| | View in PubMed
- The kSORT assay to detect renal transplant patients at high risk for acute rejection: results of the multicenter AART study.| | View in PubMed
- Endothelial cell antibodies associated with novel targets and increased rejection.| | View in PubMed
- A circulating antibody panel for pretransplant prediction of FSGS recurrence after kidney transplantation.| | View in PubMed
- Inhibition of intracellular clusterin attenuates cell death in nephropathic cystinosis.| | View in PubMed
- Transcriptional profiling of belatacept and calcineurin inhibitor therapy in renal allograft recipients.| | View in PubMed
- Quality of life is improved and kidney function preserved in patients with nephropathic cystinosis treated for 2 years with delayed-release cysteamine bitartrate.| | View in PubMed
- Optimization for peptide sample preparation for urine peptidomics.| | View in PubMed
- Identification of common blood gene signatures for the diagnosis of renal and cardiac acute allograft rejection.| | View in PubMed
- The identification of novel potential injury mechanisms and candidate biomarkers in renal allograft rejection by quantitative proteomics.| | View in PubMed
- A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantation.| | View in PubMed
- Quality of life after organ transplantation in children.| | View in PubMed
- Biologic markers of chronic GVHD.| | View in PubMed
- Moving beyond HLA: a review of nHLA antibodies in organ transplantation.| | View in PubMed
- A rapid noninvasive assay for the detection of renal transplant injury.| | View in PubMed
- Multicenter evaluation of a standardized protocol for noninvasive gene expression profiling.| | View in PubMed
- Identification of gene microarray expression profiles in patients with chronic graft-versus-host disease following allogeneic hematopoietic cell transplantation.| | View in PubMed
- Immune response profiling identifies autoantibodies specific to Moyamoya patients.| | View in PubMed
- The clinical impact of humoral immunity in pediatric renal transplantation.| | View in PubMed
- Significance and suppression of redundant IL17 responses in acute allograft rejection by bioinformatics based drug repositioning of fenofibrate.| | View in PubMed
- A common blood gene assay predates clinical and histological rejection in kidney and heart allografts.| | View in PubMed
- Discovery and customized validation of antibody targets by protein arrays and indirect ELISA.| | View in PubMed
- The pits and pearls in translating operational tolerance biomarkers into clinical practice.| | View in PubMed
- A peripheral blood diagnostic test for acute rejection in renal transplantation.| | View in PubMed
- p62/SQSTM1 prominently accumulates in renal proximal tubules in nephropathic cystinosis.| | View in PubMed
- Stanniocalcin supports the functional adaptation of adult-sized kidneys transplanted into the pediatric recipients.| | View in PubMed
- Complete steroid avoidance is effective and safe in children with renal transplants: a multicenter randomized trial with three-year follow-up.| | View in PubMed
- Subclinical inflammation and chronic renal allograft injury in a randomized trial on steroid avoidance in pediatric kidney transplantation.| | View in PubMed
- Protein and peptide biomarkers in organ transplantation.| | View in PubMed
- A randomized controlled crossover trial with delayed-release cysteamine bitartrate in nephropathic cystinosis: effectiveness on white blood cell cystine levels and comparison of safety.| | View in PubMed
- Guidelines for the use and interpretation of assays for monitoring autophagy.| | View in PubMed
- The bumpy road of genomic medicine in transplantation: lessons from studies on calcineurin inhibitor nephrotoxicity.| | View in PubMed
- Tolerance and withdrawal of immunosuppressive drugs in patients given kidney and hematopoietic cell transplants.| | View in PubMed
- A common peripheral blood gene set for diagnosis of operational tolerance in pediatric and adult liver transplantation.| | View in PubMed
- Non-HLA antibodies to immunogenic epitopes predict the evolution of chronic renal allograft injury.| | View in PubMed
- Cell-free DNA as a measure of transplant injury.| | View in PubMed
- Profiling of autoantibodies in IgA nephropathy, an integrative antibiomics approach.| | View in PubMed
- Recent advances in biomarker discovery in solid organ transplant by proteomics.| | View in PubMed
- The coin toss of B cells in rejection and tolerance: danger versus defense.| | View in PubMed
- The dual role of epithelial-to-mesenchymal transition in chronic allograft injury in pediatric renal transplantation.| | View in PubMed
- Functional proteogenomics--embracing complexity.| | View in PubMed
- Progressive histological damage in renal allografts is associated with expression of innate and adaptive immunity genes.| | View in PubMed
- Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease.| | View in PubMed
- Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis.| | View in PubMed
- Soluble human leukocyte antigen-G in pediatric renal transplantation.| | View in PubMed
- Applications of translational bioinformatics in transplantation.| | View in PubMed
- Rituximab treatment for recurrence of nephrotic syndrome in a pediatric patient after renal transplantation for congenital nephrotic syndrome of Finnish type.| | View in PubMed
- Biomarkers in solid organ transplantation: establishing personalized transplantation medicine.| | View in PubMed
- Phenotypic evaluation of B-cell subsets after rituximab for treatment of acute renal allograft rejection in pediatric recipients.| | View in PubMed
- Profiling the proteome in renal transplantation.| | View in PubMed
- Transplantomics and biomarkers in organ transplantation: a report from the first international conference.| | View in PubMed
- Organ transplantation after cardiac death.| | View in PubMed
- Efficacy and safety of thymoglobulin induction as an alternative approach for steroid-free maintenance immunosuppression in pediatric renal transplantation.| | View in PubMed
- Protein microarrays discover angiotensinogen and PRKRIP1 as novel targets for autoantibodies in chronic renal disease.| | View in PubMed
- Analysis of clinical variables associated with tolerance in pediatric liver transplant recipients.| | View in PubMed
- Expression of soluble HLA-G identifies favorable outcomes in liver transplant recipients.| | View in PubMed
- Differential immunogenicity and clinical relevance of kidney compartment specific antigens after renal transplantation.| | View in PubMed
- Harnessing the diversity of the human T-cell repertoire: a monitoring tool for transplantation tolerance?| | View in PubMed
- Comparison of multiplex meta analysis techniques for understanding the acute rejection of solid organ transplants.| | View in PubMed
- Abnormal mitochondrial autophagy in nephropathic cystinosis.| | View in PubMed
- Insights into novel cellular injury mechanisms by gene expression profiling in nephropathic cystinosis.| | View in PubMed
- Differentially expressed RNA from public microarray data identifies serum protein biomarkers for cross-organ transplant rejection and other conditions.| | View in PubMed
- Molecular diagnostics in transplantation.| | View in PubMed
- Monitoring calcineurin inhibitor therapy: localizing the moving target.| | View in PubMed
- Steroid minimization for sirolimus-treated renal transplant recipients.| | View in PubMed
- Pediatric kidney transplantation.| | View in PubMed
- Pediatric renal transplantation: an overview and update.| | View in PubMed
- Cell type-specific gene expression differences in complex tissues.| | View in PubMed
- Compartmental localization and clinical relevance of MICA antibodies after renal transplantation.| | View in PubMed
- Integrative urinary peptidomics in renal transplantation identifies biomarkers for acute rejection.| | View in PubMed
- The yin and yang of B cells in graft rejection and tolerance.| | View in PubMed
- Caspase-4 may play a role in loss of proximal tubules and renal injury in nephropathic cystinosis.| | View in PubMed
- Shotgun proteomics identifies proteins specific for acute renal transplant rejection.| | View in PubMed
- Mitochondrial autophagy promotes cellular injury in nephropathic cystinosis.| | View in PubMed
- BAFF may modulate the rate of B-cell repopulation after rituximab therapy for acute renal transplant rejection.| | View in PubMed
- Protein microarrays identify antibodies to protein kinase Czeta that are associated with a greater risk of allograft loss in pediatric renal transplant recipients.| | View in PubMed
- Balancing efficacy and toxicity of kidney transplant immunosuppression.| | View in PubMed
- Deconvoluting the 'omics' for organ transplantation.| | View in PubMed
- Promotion of altruistic donation.| | View in PubMed
- Long-term outcome following pediatric liver transplantation for metabolic disorders.| | View in PubMed
- Steroid-free immunosuppression in pediatric renal transplantation: rationale for and [corrected] outcomes following conversion to steroid based therapy.| | View in PubMed
- C3 polymorphisms and outcomes of renal allografts.| | View in PubMed
- Expression of complement components differs between kidney allografts from living and deceased donors.| | View in PubMed
- Steroid-free immunosuppression since 1999: 129 pediatric renal transplants with sustained graft and patient benefits.| | View in PubMed
- Standardizing resistive indices in healthy pediatric transplant recipients of adult-sized kidneys.| | View in PubMed
- Identifying compartment-specific non-HLA targets after renal transplantation by integrating transcriptome and "antibodyome" measures.| | View in PubMed
- Calcineurin inhibitor nephrotoxicity.| | View in PubMed
- Using gene arrays in diagnosis of rejection.| | View in PubMed
- Interpreting the proteome and peptidome in transplantation.| | View in PubMed
- Combined liver-kidney transplantation in children: indications and outcome.| | View in PubMed
- A critical look at the immunologically favorable adult-sized kidney transplant in small children.| | View in PubMed
- Extended daclizumab monotherapy for rejection-free survival in non-adherent adolescent recipients of renal allografts.| | View in PubMed
- Out with the old, in with the new: immunosuppression minimization in children.| | View in PubMed
- A randomized, prospective trial of rituximab for acute rejection in pediatric renal transplantation.| | View in PubMed
- Microarrays: monitoring for transplant tolerance and mechanistic insights.| | View in PubMed
- The proteogenomic path towards biomarker discovery.| | View in PubMed
- Renal transplantation in children with thrombosis of the inferior vena cava requires careful assessment and planning.| | View in PubMed
- Patient selection critical for calcineurin inhibitor withdrawal in pediatric kidney transplantation.| | View in PubMed
- "To B or not to B?" B-cells and graft rejection.| | View in PubMed
- In praise of arrays.| | View in PubMed
- Characterization of intra-graft B cells during renal allograft rejection.| | View in PubMed
- Optimizing protein recovery for urinary proteomics, a tool to monitor renal transplantation.| | View in PubMed
- Maturation of dose-corrected tacrolimus predose trough levels in pediatric kidney allograft recipients.| | View in PubMed
- Looking into the crystal chip: can microarrays predict graft function?| | View in PubMed
- Liposomal amphotericin B associated with severe hyperphosphatemia.| | View in PubMed
- Potential influence of tacrolimus and steroid avoidance on early graft function in pediatric renal transplantation.| | View in PubMed
- Interference of globin genes with biomarker discovery for allograft rejection in peripheral blood samples.| | View in PubMed
- Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance.| | View in PubMed
- Transplant reno-vascular stenoses associated with early erythropoietin use.| | View in PubMed
- The evolution of nonimmune histological injury and its clinical relevance in adult-sized kidney grafts in pediatric recipients.| | View in PubMed
- Immunosuppression minimization in pediatric transplantation.| | View in PubMed
- Optimizing outcomes for neonatal ARPKD.| | View in PubMed
- Sirolimus is not always responsible for new-onset proteinuria after conversion for chronic allograft nephropathy.| | View in PubMed
- Subclinical cytomegalovirus and Epstein-Barr virus viremia are associated with adverse outcomes in pediatric renal transplantation.| | View in PubMed
- Proteinuria in pediatric renal transplant recipients during the first 60 post-transplant days.| | View in PubMed
- Designer genes: Filling the gap in transplantation.| | View in PubMed
- Successful renal transplantation in high-risk small children with a completely thrombosed inferior vena cava.| | View in PubMed
- A novel, semiquantitative, clinically correlated calcineurin inhibitor toxicity score for renal allograft biopsies.| | View in PubMed
- Microarrays: a monitoring tool for transplant patients?| | View in PubMed
- Chipping into the human genome: novel insights for transplantation.| | View in PubMed
- Option of pre-emptive nephrectomy and renal transplantation for Bartter's syndrome.| | View in PubMed
- Three cases of suspected antibody-mediated rejection.| | View in PubMed
- Transcriptional analysis of the molecular basis of human kidney aging using cDNA microarray profiling.| | View in PubMed
- Steroid elimination is coming of age.| | View in PubMed
- Mycophenolate mofetil in pediatric renal transplantation.| | View in PubMed
- Expression profiling of murine double-negative regulatory T cells suggest mechanisms for prolonged cardiac allograft survival.| | View in PubMed
- Corticosteroid avoidance in pediatric renal transplantation.| | View in PubMed
- Gastrointestinal leukocytoclastic vasculitis: an adverse effect of sirolimus.| | View in PubMed
- Vulnerability of small pediatric recipients to laparoscopic living donor kidneys.| | View in PubMed
- First NIH/Office of Rare Diseases Conference on Cystinosis: past, present, and future.| | View in PubMed
- Management of methylmalonic acidaemia by combined liver-kidney transplantation.| | View in PubMed
- Correlation between gene expression and morphological alterations in baboon carotid after balloon dilatation injury.| | View in PubMed
- Microangiopathy of brain, retina, and inner ear (Susac's syndrome) in an adolescent female presenting as acute disseminated encephalomyelitis.| | View in PubMed
- Arraying the orchestration of allograft pathology.| | View in PubMed
- Corticosteroid avoidance in pediatric renal transplantation: can it be achieved?| | View in PubMed
- Microarrays: interrogating the transplant transcriptosome.| | View in PubMed
- Noncirrhotic portal hypertension in association with juvenile nephropathic cystinosis: case presentation and review of the literature.| | View in PubMed
- Postdialysis albumin: a better nutrition marker in pediatric hemodialysis patients?| | View in PubMed
- A typology of non-adherence in pediatric renal transplant recipients.| | View in PubMed
- One hundred percent patient and kidney allograft survival with simultaneous liver and kidney transplantation in infants with primary hyperoxaluria: a single-center experience.| | View in PubMed
- Continued superior outcomes with modification and lengthened follow-up of a steroid-avoidance pilot with extended daclizumab induction in pediatric renal transplantation.| | View in PubMed
- Applications of microarrays to renal transplantation: progress and possibilities.| | View in PubMed
- Safety and risk stratification of percutaneous biopsies of adult-sized renal allografts in infant and older pediatric recipients.| | View in PubMed
- Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling.| | View in PubMed
- Chronic rejection: prospects for therapeutic intervention in fibroproliferative vascular disease.| | View in PubMed
- Microarrays: new tools for transplantation research.| | View in PubMed
- Increased expression of cytotoxic effector molecules: different interpretations for steroid-based and steroid-free immunosuppression.| | View in PubMed
- Molecular profiling of anemia in acute renal allograft rejection using DNA microarrays.| | View in PubMed
- Promising early outcomes with a novel, complete steroid avoidance immunosuppression protocol in pediatric renal transplantation.| | View in PubMed
- Visual loss caused by pseudotumor cerebri in an infant on peritoneal dialysis.| | View in PubMed
- Genomic analysis of renal allograft dysfunction using cDNA microarrays.| | View in PubMed
- Granulysin expression is a marker for acute rejection and steroid resistance in human renal transplantation.| | View in PubMed
- Adult-size kidneys without acute tubular necrosis provide exceedingly superior long-term graft outcomes for infants and small children: a single center and UNOS analysis. United Network for Organ Sharing.| | View in PubMed
- Sodium ferric gluconate therapy in renal transplant and renal failure patients.| | View in PubMed
- A 100% 2-year graft survival can be attained in high-risk 15-kg or smaller infant recipients of kidney allografts.| | View in PubMed
- Renal perfusion in infant recipients of adult-sized kidneys is a critical risk factor.| | View in PubMed
- Pulmonary capillary leak syndrome with intravenous cyclosporin A in pediatric renal transplantation.| | View in PubMed
- A new, unique and simple method for ureteral implantation in kidney recipients with small, defunctionalized bladders.| | View in PubMed
- Transplantation of adult-sized kidneys into infants induces major blood flow changes.| | View in PubMed
- Successful transplantation of adult-sized kidneys into infants requires maintenance of high aortic blood flow.| | View in PubMed
- G protein alpha subunit multigene family in the Japanese puffer fish Fugu rubripes: PCR from a compact vertebrate genome.| | View in PubMed