Biography
Ascher is a graduate of the University of Michigan, Ann Arbor, where she earned her medical degree. She completed a general surgery residency and clinical transplant fellowship at the University of Minnesota, where she later joined the faculty and became clinical director of the liver transplant program.
Ascher is a fellow of the American College of Surgeons. She is a member of numerous other medical societies, including the American Society of Transplant Surgeons, in which she has served as president.
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Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
University of Minnesota | Fellowship | Transplant Surgery | 1982 |
University of Minnesota | Residency | General Surgery | 1981 |
University of Michigan | 1974 |
Board Certifications
- American Board of Surgery, 1982, renewed 2012
Clinical Expertise
End-Stage Kidney Disease
Fulminant Hepatic Failure
Hepatitis B
Hepatitis C
Hepatocellular Carcinoma (Liver Cancer)
Kidney Transplantation
Liver Cysts
Living Donor Kidney Transplantation
Living Donor Liver Transplantation
Liver Transplantation
Non-alcoholic Fatty Liver Disease
Pediatric Liver Transplantation
Pediatric Kidney Transplantation
Portal Hypertension
In the News
Grants and Funding
- ALLOGRAFT RESPONSE TO LIVER TISSUE | NIH | 1988-09-30 - 1995-09-29 | Role: Principal Investigator
- LIVER TRANSPLANTATION CENTERS | NIH/NIDDK | 1990-01-01 - 1995-03-31 | Role: Principal Investigator
- ORGAN TRANSPLANTS: ANALYSIS OF MIGRATING LYMPHOCYTES | NIH | 1984-07-01 - 1987-06-30 | Role: Principal Investigator
Research Narrative
I. RECURRENT DISEASE AFTER LIVER TRANSPLANT
The NIH Liver Transplant Data Base has been extended to address the important issue of disease recurrence after liver transplantation. Although short term liver transplant results have improved markedly over the past ten years, it is apparent that disease recurrence is an important source of patient morbidity and graft loss. Long term following of greater than 1000 patients in the Liver Transplant Data Base will facilitate our understanding of the factors associated with graft recurrence.
II. EXPANDED CRITERIA FOR LIVER TRANSPLANT FOR HEPATOCELLULAR CARCINOMA
We have redefined the criteria for liver transplantation beyond the Milan criteria. The UCSF criteria enables additional patients to benefit from liver transplants without compromising outcome.
Research Interests
- Clinical Transplantation
- Recurrence After Liver Transplantation
- Transplant Policy
- Transplant Ethics
Publications
- A Last Hurrah: Reply to Sharif et al Regarding China.| | View in PubMed
- Anesthesia and Critical Care for the Prediction and Prevention for Small-for-size Syndrome: Guidelines from the ILTS-iLDLT-LTSI Consensus Conference.| | View in PubMed
- Management of Established Small-for-size Syndrome in Post Living Donor Liver Transplantation: Medical, Radiological, and Surgical Interventions: Guidelines From the ILTS-iLDLT-LTSI Consensus Conference.| | View in PubMed
- Post Living Donor Liver Transplantation Small-for-size Syndrome: Definitions, Timelines, Biochemical, and Clinical Factors for Diagnosis: Guidelines From the ILTS-iLDLT-LTSI Consensus Conference.| | View in PubMed
- DCD liver transplant in patients with a MELD over 35.| | View in PubMed
- Preventing Small-for-size Syndrome in Living Donor Liver Transplantation: Guidelines From the ILTS-iLDLT-LTSI Consensus Conference.| | View in PubMed
- Organ Donation and Transplantation in China.| | View in PubMed
- Sex-based Disparities in Access to Liver Transplantation for Waitlisted Patients With Model for End-stage Liver Disease Score of 40.| | View in PubMed
- Comments on Experience With Establishing a Robotic Donor Hepatectomy Program for Pediatric Liver Transplantation.| | View in PubMed
- The John S. Najarian symposium: The past, present, and future of surgery and transplantation, May 20, 2022, Minneapolis, MN.| | View in PubMed
- Addressing sex-based disparities in solid organ transplantation in the United States - a conference report.| | View in PubMed
- Comparison of Biliary Complications Rates After Brain Death, Donation After Circulatory Death, and Living-Donor Liver Transplantation: A Single-Center Cohort Study.| | View in PubMed
- The Reality of Inadequate Patient Care and the Need for a Global Action Framework in Organ Donation and Transplantation.| | View in PubMed
- Optimizing pre-donation physiologic evaluation for enhanced recovery after living liver donation - Systematic review and multidisciplinary expert panel recommendations.| | View in PubMed
- Novel Benchmark Values for Redo Liver Transplantation: Does the Outcome Justify the Effort?| | View in PubMed
- A novel microsurgical reconstruction technique in a living-related liver donor hepatic artery dissection using the native hepatic artery.| | View in PubMed
- Long-term Outcomes Following Kidney and Liver Transplant in Recipients With HIV.| | View in PubMed
- International Travel for Liver Transplantation: A Comprehensive Assessment of the Impact on the United States Transplant System.| | View in PubMed
- Advantages and Limitations of Clinical Scores for Donation After Circulatory Death Liver Transplantation.| | View in PubMed
- Expedited evaluation for liver transplantation: A critical look at processes and outcomes.| | View in PubMed
- Travel for Transplantation: A Review of Domestic and International Travel for Liver Transplantation in the United States.| | View in PubMed
- Surgical Trainee Well-Being: A Synergy of Individual and System-Level Interventions.| | View in PubMed
- Correction to: Expanding controlled donation after the circulatory determination of death: statement from an international collaborative.| | View in PubMed
- Meeting Report: First State of the Art Meeting on Gender Disparity in Kidney Transplantation in the Asia-Pacific.| | View in PubMed
- "The use of bilateral continuous erector spinae plane blocks for postoperative analgesia after right-sided living donor hepatectomy: A feasibility study".| | View in PubMed
- Retransplantation After Living Donor Liver Transplantation: Data from the Adult to Adult Living Donor Liver Transplantation Study.| | View in PubMed
- Obesity is a risk factor for progression to kidney transplant waitlisting after liver transplantation.| | View in PubMed
- The Importance of Bringing Transplantation Tolerance to the Clinic.| | View in PubMed
- Standardizing Discharge Opioid Prescriptions in Kidney Transplant Patients Decreases Opioid Usage.| | View in PubMed
- Live Donor Liver Transplantation in the United States: Impact of Share 35 on Live Donor Utilization.| | View in PubMed
- Enhanced Stress Resilience Training in Surgeons: Iterative Adaptation and Biopsychosocial Effects in 2 Small Randomized Trials.| | View in PubMed
- Expanding controlled donation after the circulatory determination of death: statement from an international collaborative.| | View in PubMed
- A world-wide survey on kidney transplantation practices in breast cancer survivors: The need for new management guidelines.| | View in PubMed
- Exploration of Individual and System-Level Well-being Initiatives at an Academic Surgical Residency Program: A Mixed-Methods Study.| | View in PubMed
- Opioid Use and Liver Transplantation.| | View in PubMed
- Setting rules for the sandbox: A response to "Successfully sharing the sandbox: A perspective on combined DCD liver and heart donor procurement".| | View in PubMed
- Expanding living donor liver transplantation: Report of first US living donor liver transplant chain.| | View in PubMed
- Opioid use prior to liver transplant is associated with increased risk of death after transplant.| | View in PubMed
- COVID-19 and Abdominal Transplant: A Stepwise Approach to Practice During Pandemic Conditions.| | View in PubMed
- In Memoriam: Dr. John Najarian, 1927-2020.| | View in PubMed
- Global Transplantation COVID Report March 2020.| | View in PubMed
- Training of Male and Female Surgical Residents.| | View in PubMed
- Author's Response.| | View in PubMed
- Implementing an opioid reduction protocol in renal transplant recipients.| | View in PubMed
- Quantifying Sex-Based Disparities in Liver Allocation.| | View in PubMed
- A Virtual Crossmatch-based Strategy Facilitates Sharing of Deceased Donor Kidneys for Highly Sensitized Recipients.| | View in PubMed
- Living Donor Liver Transplant for Alcoholic Liver Disease: Data from the Adult-to-adult Living Donor Liver Transplantation Study.| | View in PubMed
- Key factors for implementing mindfulness-based burnout interventions in surgery.| | View in PubMed
- The Utility of ECMO After Liver Transplantation: Experience at a High-volume Transplant Center and Review of the Literature.| | View in PubMed
- Glass Slippers and Glass Cliffs: Fitting In and Falling Off.| | View in PubMed
- Societal and Professional Obligation in the Care of the Living Organ Donor.| | View in PubMed
- Bi-organ paired exchange-Sentinel case of a liver-kidney swap.| | View in PubMed
- Efficacy of Mindfulness-Based Cognitive Training in Surgery: Additional Analysis of the Mindful Surgeon Pilot Randomized Clinical Trial.| | View in PubMed
- Call for an End to Unethical Transplant Practices: A Concerted Effort by the Transplant Community.| | View in PubMed
- Feasibility of Formal Mindfulness-Based Stress-Resilience Training Among Surgery Interns: A Randomized Clinical Trial.| | View in PubMed
- Deceased Donor Organ Transplantation Performed in the United States for Noncitizens and Nonresidents.| | View in PubMed
- The Impact of Renal Insufficiency After Liver Transplantation.| | View in PubMed
- Living Donor Liver Transplantation for Alcoholic Liver Disease.| | View in PubMed
- A Formula to Calculate Standard Liver Volume Using Thoracoabdominal Circumference.| | View in PubMed
- Burnout and Stress Among US Surgery Residents: Psychological Distress and Resilience.| | View in PubMed
- Opposition to irresponsible global kidney exchange.| | View in PubMed
- Clinical Trials for Immunosuppression in Transplantation: The Case for Reform and Change in Direction.| | View in PubMed
- Criminal Organ Retrieval: Unconscionable.| | View in PubMed
- The Transplantation Society Believes a Policy of Engagement Will Facilitate Organ Donation Reform in China.| | View in PubMed
- Biliary complications following living donor hepatectomy.| | View in PubMed
- Impact of Graft Selection on Donor and Recipient Outcomes After Living Donor Liver Transplantation.| | View in PubMed
- Medical Students' Perceptions of Surgeons: Implications for Teaching and Recruitment.| | View in PubMed
- Nancy L. Ascher, MD, PhD: Professor and Chair, Department of Surgery, UCSF; Past-President, ASTS; President-elect, The Transplantation Society.| | View in PubMed
- Improving interprofessional collaboration: evaluation of implicit attitudes in the surgeon-nurse relationship.| | View in PubMed
- Perceptions of surgeons: what characteristics do women surgeons prefer in a colleague?| | View in PubMed
- Patient perceptions of female surgeons: how surgeon demeanor and type of surgery affect patient preference.| | View in PubMed
- Ex vivo split-liver transplantation: the true right/left split.| | View in PubMed
- Left hepatectomy versus right hepatectomy for living donor liver transplantation: shifting the risk from the donor to the recipient.| | View in PubMed
- Asian American adolescents' willingness to donate organs and engage in family discussion about organ donation and transplantation.| | View in PubMed
- Use of living donor liver transplantation varies with the availability of deceased donor liver transplantation.| | View in PubMed
- Outcomes with split liver transplantation in 106 recipients: the University of California, San Francisco, experience from 1993 to 2010.| | View in PubMed
- Outcomes of surgical repair of bile leaks and strictures after adult-to-adult living donor liver transplant.| | View in PubMed
- Comparison of biliary complications in adult living-donor liver transplants performed at two busy transplant centers.| | View in PubMed
- Emergent orthotopic liver transplantation for hemorrhage from a giant cavernous hepatic hemangioma: case report and review.| | View in PubMed
- Development of the Organ Donation and Transplantation Knowledge Survey for use in Asian American adolescents.| | View in PubMed
- Left lobe adult-to-adult living donor liver transplantation: small grafts and hemiportocaval shunts in the prevention of small-for-size syndrome.| | View in PubMed
- Excellent outcome following down-staging of hepatocellular carcinoma prior to liver transplantation: an intention-to-treat analysis.| | View in PubMed
- Operating room assist: surgical mentorship and operating room experience for preclerkship medical students.| | View in PubMed
- Laparoscopic bariatric surgery improves candidacy in morbidly obese patients awaiting transplantation.| | View in PubMed
- Liver transplantation at UCSF--a 20-year experience.| | View in PubMed
- HIV-infected liver and kidney transplant recipients: 1- and 3-year outcomes.| | View in PubMed
- Liver transplantation for hepatocellular carcinoma: validation of the UCSF-expanded criteria based on preoperative imaging.| | View in PubMed
- A surgical skills elective to expose preclinical medical students to surgery.| | View in PubMed
- Tribute: Dr. Olga Jonasson. Born in Peoria, Illinois, August 12, 1934. Died in Chicago, Illinois, August 30, 2006.| | View in PubMed
- Enhancing the mission of academic surgery by promoting scientific writing skills.| | View in PubMed
- Central venous pressure monitoring during living right donor hepatectomy.| | View in PubMed
- A randomized trial of exercise and dietary counseling after liver transplantation.| | View in PubMed
- Report of a National Conference on Donation after cardiac death.| | View in PubMed
- A prospective study on downstaging of hepatocellular carcinoma prior to liver transplantation.| | View in PubMed
- The Department of Surgery, University of California, San Francisco.| | View in PubMed
- High incidence of recurrence and hematologic events following liver transplantation for Budd-Chiari syndrome.| | View in PubMed
- The use of stents for duct-to-duct anastomoses of biliary reconstruction in orthotopic liver transplantation.| | View in PubMed
- The impact of pre-operative loco-regional therapy on outcome after liver transplantation for hepatocellular carcinoma.| | View in PubMed
- Objective measures of health-related quality of life over 24 months post-liver transplantation.| | View in PubMed
- Liver transplantation for hepatocellular carcinoma: lessons from the first year under the Model of End-Stage Liver Disease (MELD) organ allocation policy.| | View in PubMed
- New onset diabetes mellitus after liver transplantation: the critical role of hepatitis C infection.| | View in PubMed
- Split-liver transplantation in the United States: outcomes of a national survey.| | View in PubMed
- Prediction of survival after liver retransplantation for late graft failure based on preoperative prognostic scores.| | View in PubMed
- Death from donor-transmitted malignancy despite emergency liver retransplantation.| | View in PubMed
- Expanding the donor pool: can the Spanish model work in the United States?| | View in PubMed
- Effects of exercise training on coronary heart disease risk factors in renal transplant recipients.| | View in PubMed
- Kidney and liver transplantation in human immunodeficiency virus-infected patients: a pilot safety and efficacy study.| | View in PubMed
- A follow-up analysis of the pattern and predictors of dropout from the waiting list for liver transplantation in patients with hepatocellular carcinoma: implications for the current organ allocation policy.| | View in PubMed
- Analysis of research projects in living donor organ transplantation.| | View in PubMed
- What's new in general surgery: transplantation.| | View in PubMed
- Intraoperative hemodynamics and liver function in adult-to-adult living liver donors.| | View in PubMed
- Liver transplantation for hepatocellular carcinoma: analysis of survival according to the intention-to-treat principle and dropout from the waiting list.| | View in PubMed
- Liver transplantation for hepatocellular carcinoma: comparison of the proposed UCSF criteria with the Milan criteria and the Pittsburgh modified TNM criteria.| | View in PubMed
- Allograft rejection in pediatric liver transplantation: Comparison between cadaveric and living related donors.| | View in PubMed
- A randomized trial of exercise training after renal transplantation.| | View in PubMed
- Donor health assessment after living-donor liver transplantation.| | View in PubMed
- Liver transplantation for nonviral, nonmalignant diseases:problem of recurrence.| | View in PubMed
- Posttransplantation growth in pediatric liver recipients.| | View in PubMed
- Solid organ transplantation in HIV-positive patients.| | View in PubMed
- Mixed allogeneic chimerism as a reliable model for composite tissue allograft tolerance induction across major and minor histocompatibility barriers.| | View in PubMed
- Liver transplantation for hepatocellular carcinoma: expansion of the tumor size limits does not adversely impact survival.| | View in PubMed
- Physical activity and health-related quality of life in liver transplant recipients.| | View in PubMed
- Posttransplantation lymphoproliferative disorders in pediatric patients undergoing liver transplantation.| | View in PubMed
- Immunosuppressant substitutes in liver transplantation.| | View in PubMed
- A calcineurin inhibitor-sparing regimen with sirolimus, mycophenolate mofetil, and anti-CD25 mAb provides effective immunosuppression in kidney transplant recipients with delayed or impaired graft function.| | View in PubMed
- Experience with the use of sirolimus in liver transplantation--use in patients for whom calcineurin inhibitors are contraindicated.| | View in PubMed
- Surgical anatomy of the left lateral segment as applied to living-donor and split-liver transplantation: a clinicopathologic study.| | View in PubMed
- Prolonged cold ischemia time obviates the benefits of 0 HLA mismatches in renal transplantation.| | View in PubMed
- A non-cleavable mutant of Fas ligand does not prevent neutrophilic destruction of islet transplants.| | View in PubMed
- A dendritic cell line genetically modified to express CTLA4-IG as a means to prolong islet allograft survival.| | View in PubMed
- Flow cytometry crossmatching as a predictor of acute rejection in sensitized recipients of cadaveric renal transplants.| | View in PubMed
- HCV-related fibrosis progression following liver transplantation: increase in recent years.| | View in PubMed
- Experience with daclizumab in liver transplantation: renal transplant dosing without calcineurin inhibitors is insufficient to prevent acute rejection in liver transplantation.| | View in PubMed
- Liver transplantation for autoimmune hepatitis: rejection and recurrence.| | View in PubMed
- Four-year follow-up of mycophenolate mofetil for graft rescue in liver allograft recipients.| | View in PubMed
- Mycophenolate mofetil, microemulsion cyclosporine, and prednisone as primary immunosuppression for pediatric liver transplant recipients.| | View in PubMed
- Effect of systemic cyclosporine on tumor recurrence after liver transplantation in a model of hepatocellular carcinoma.| | View in PubMed
- Hepatic artery pseudoaneurysm with hemobilia following angioplasty after liver transplantation.| | View in PubMed
- Donor-specific tolerance induction in composite tissue allografts.| | View in PubMed
- Hepatitis after liver transplantation: the role of the known and unknown viruses.| | View in PubMed
- Possible recurrence of primary sclerosing cholangitis following living-related liver transplantation: report of a case.| | View in PubMed
- Biliary complications of reduced-organ liver transplantation.| | View in PubMed
- Incidence and clinical consequences of surface and polymerase gene mutations in liver transplant recipients on hepatitis B immunoglobulin.| | View in PubMed
- The role of pediatricians in the care of children with liver transplants.| | View in PubMed
- Tolerance induction using bone marrow transplantation.| | View in PubMed
- Single-center long-term results of renal transplantation for IgA nephropathy.| | View in PubMed
- Risks associated with conversion of stable patients after liver transplantation to the microemulsion formulation of cyclosporine.| | View in PubMed
- Fas ligand expression on islets as well as multiple cell lines results in accelerated neutrophilic rejection.| | View in PubMed
- Predictors of the cost of liver transplantation.| | View in PubMed
- Progress in transgenic pigs for xenotransplantation.| | View in PubMed
- Quo vadis, my transplant fellow: a discussion of transplant surgery fellowship training activity in the United States and Canada: 1991-1997. Education Committee of the American Society of Transplant Surgeons.| | View in PubMed
- Interleukin-2 receptor antibody therapy.| | View in PubMed
- Pathological changes in yearly protocol liver biopsy specimens from healthy pediatric liver recipients.| | View in PubMed
- The impact of surgical complications after liver transplantation on resource utilization.| | View in PubMed
- Planned exploration of pediatric liver transplant recipients reduces posttransplant morbidity and lowers length of hospitalization.| | View in PubMed
- Retransplantation of patients with severe posttransplant hepatitis B in the first allograft.| | View in PubMed
- Auxiliary liver transplant in fulminant failure.| | View in PubMed
- Increased immune responses to regenerating partial liver grafts in the rat.| | View in PubMed
- Hepatitis G virus in patients with cryptogenic liver disease undergoing liver transplantation.| | View in PubMed
- A controlled analysis of the transjugular intrahepatic portosystemic shunt in liver transplant recipients. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Liver Transplantation Database.| | View in PubMed
- The role of the host immune state in recurrent hepatitis C.| | View in PubMed
- Antibody to the host cellular gene-derived epitope GOR-1 in liver transplant recipients with hepatitis C virus infection.| | View in PubMed
- Clonal deletion is one mechanism responsible for tolerance in mixed hematopoietic chimeras.| | View in PubMed
- Hepatitis G virus infection in patients with hepatitis C virus infection undergoing liver transplantation.| | View in PubMed
- Prophylaxis in liver transplant recipients using a fixed dosing schedule of hepatitis B immunoglobulin.| | View in PubMed
- Severity of liver disease in liver transplantation recipients with hepatitis C virus infection: relationship to genotype and level of viremia.| | View in PubMed
- Functional analysis of grafts from living donors. Implications for the treatment of older recipients.| | View in PubMed
- Failure patterns of cryopreserved vein grafts in liver transplantation.| | View in PubMed
- Liver transplantation improves survival of rats bearing hepatoma-3924A.| | View in PubMed
- SCID mouse as a model for transplantation studies.| | View in PubMed
- Decreased mortality from technical failure improves results in pediatric liver transplantation.| | View in PubMed
- Hepatotoxins and liver transplantation decrease pulmonary metastases in rats with hepatoma.| | View in PubMed
- Living related donor liver transplantation: the UCSF experience.| | View in PubMed
- Strategies for tolerance induction: potential applications in living donor liver transplantation.| | View in PubMed
- Fifty-percent partial liver transplantation in the rat.| | View in PubMed
- Expanding the immunosuppressive repertoire.| | View in PubMed
- Advances in biliary reconstruction after liver transplantation.| | View in PubMed
- Interferon alfa for recurrent hepatitis B infection after liver transplantation.| | View in PubMed
- Transmission of hepatitis B virus through allotransplantation.| | View in PubMed
- United Network for Organ Sharing center-specific data: our report card.| | View in PubMed
- Incidence and significance of Aspergillus cultures following liver and kidney transplantation.| | View in PubMed
- The use of the T tube after orthotopic liver transplantation.| | View in PubMed
- Cryoglobulinemia presenting after liver transplantation.| | View in PubMed
- Hepatitis C dilemma?| | View in PubMed
- Detection of hepatitis C after liver transplantation. Four serologic tests compared.| | View in PubMed
- Hepatic granulomas following liver transplantation. Clinicopathologic features in 42 patients.| | View in PubMed
- Increased efficacy of CSA following rearterialization in the rat OLTX model.| | View in PubMed
- Influence of donor age on graft survival after liver transplantation--United Network for Organ Sharing Registry.| | View in PubMed
- Issues in xenotransplantation.| | View in PubMed
- Posttransplantation lymphoproliferative disorder in patients under primary tacrolimus (FK 506) immunosuppression.| | View in PubMed
- Liver transplantation for sclerosing cholangitis.| | View in PubMed
- Total vascular exclusion for major hepatectomy in patients with abnormal liver parenchyma.| | View in PubMed
- Amelioration of acute GVHD disease and reestablishment of tolerance by short term treatment with anti TCR antibody.| | View in PubMed
- Liver transplantation for hepatocellular carcinoma: results with preoperative chemoembolization.| | View in PubMed
- Primary sclerosing cholangitis: liver transplantation or biliary surgery.| | View in PubMed
- Time course of cyclosporine and ist motabolites in blood, liver and spleen of naive Lewis rats: comparison with preliminary data obtained in transplanted animals.| | View in PubMed
- Two-year outcome following transjugular intrahepatic portosystemic shunt for variceal bleeding: results in 90 patients.| | View in PubMed
- Hepatocyte transplantation.| | View in PubMed
- FK506 (tacrolimus) compared with cyclosporine for primary immunosuppression after pediatric liver transplantation. Results from the U.S. Multicenter Trial.| | View in PubMed
- Impact of transjugular intrahepatic portosystemic shunts on liver transplantation: a controlled analysis. NIDDK Liver Transplantation Database.| | View in PubMed
- The risk of transmission of hepatitis B from HBsAg(-), HBcAb(+), HBIgM(-) organ donors.| | View in PubMed
- Fulminant hepatic failure: summary of a workshop.| | View in PubMed
- Immunosuppressive therapy in liver transplantation: principles and practice.| | View in PubMed
- Microchimerism in organ transplantation.| | View in PubMed
- Effect of cyclosporine dosing on creatinine levels in hepatic transplant recipients.| | View in PubMed
- Interferon-alpha therapy for hepatitis C virus infection after liver transplantation.| | View in PubMed
- Liver transplantation for hepatitis C virus-related cirrhosis.| | View in PubMed
- Predicting recidivism after orthotopic liver transplantation for alcoholic liver disease.| | View in PubMed
- Enhancement of islet allograft survival in mice treated with MHC class I specific F(ab')2 alloantibody.| | View in PubMed
- Quantitation of hepatitis C virus RNA in liver transplant recipients.| | View in PubMed
- beta-2 Microglobulin gene disruption prolongs murine islet allograft survival in NOD mice.| | View in PubMed
- Prolongation of in vivo mouse islet allograft survival by modulation of MHC class I antigen.| | View in PubMed
- The increased efficacy and decreased nephrotoxicity of a cyclosporine liposome.| | View in PubMed
- "Occult" hepatitis B virus as source of infection in liver transplant recipients.| | View in PubMed
- Liver transplantation and the Najarian footprint.| | View in PubMed
- Major histocompatibility complex class I deficiency prolongs islet allograft survival.| | View in PubMed
- Reversal of chronic rejection after treatment failure with FK506 and RS61443.| | View in PubMed
- Immunosuppressive therapy as a determinant of transplantation outcomes.| | View in PubMed
- Liver transplantation for fulminant hepatic failure.| | View in PubMed
- New immunologic insights into mechanisms of allograft rejection.| | View in PubMed
- Creation of transjugular intrahepatic portosystemic shunts with the wallstent endoprosthesis: results in 100 patients.| | View in PubMed
- IL-2 and IL-5 gene expression in response to alloantigen in liver allograft recipients and in vitro.| | View in PubMed
- Nonoperative management of biliary leaks after orthotopic liver transplantation.| | View in PubMed
- Cirrhosis of undefined pathogenesis: absence of evidence for unknown viruses or autoimmune processes.| | View in PubMed
- Evidence for a nonclassical pathway of graft rejection involving interleukin 5 and eosinophils.| | View in PubMed
- Hepatitis C and B in liver transplantation.| | View in PubMed
- Immunosuppression and rejection in liver transplantation.| | View in PubMed
- Maintenance immunosuppression with prednisone and RS-61443 alone following liver transplantation.| | View in PubMed
- Transjugular intrahepatic portacaval stent shunts in patients with renal insufficiency.| | View in PubMed
- Estimates of organ-specific donor availability for the United States.| | View in PubMed
- Intragraft eosinophilia and interleukin-5 mRNA accompany liver allograft rejection.| | View in PubMed
- Isolation of functional MHC class I-deficient islet cells.| | View in PubMed
- Orthotopic liver transplantation for end-stage alcoholic liver disease.| | View in PubMed
- Prognostic factors for successful conversion from cyclosporine to FK 506-based immunosuppressive therapy for refractory rejection after liver transplantation. US Multicenter FK 506 Liver Study Group.| | View in PubMed
- RS-61443 for treatment-resistant human liver rejection.| | View in PubMed
- Standard sequential immunosuppression with Minnesota antilymphoblast globulin and cyclosporine vs FK 506: a comparison of early nephrotoxicity.| | View in PubMed
- T-cell receptor-V alpha gene use in sequential liver allograft biopsies.| | View in PubMed
- Use of FK 506 for the prevention of recurrent allograft rejection after successful conversion from cyclosporine for refractory rejection. US Multicenter FK 506 Liver Study Group.| | View in PubMed
- Use of Prograf (FK 506) as rescue therapy for refractory rejection after liver transplantation. US Multicenter FK 506 Liver Study Group.| | View in PubMed
- Liver transplantation at the University of California, San Francisco.| | View in PubMed
- Incidence and diagnostic features of macroregenerative nodules vs. small hepatocellular carcinoma in cirrhotic livers.| | View in PubMed
- Lipopeliosis: fat induced sinusoidal dilatation in transplanted liver mimicking peliosis hepatis.| | View in PubMed
- Hepatitis C viral infection in liver transplant recipients.| | View in PubMed
- Pulmonary hypertension associated with liver disease is not reversible after liver transplantation.| | View in PubMed
- Transjugular intrahepatic portosystemic shunts: preliminary results in 25 patients.| | View in PubMed
- A modified vascular "sleeve" anastomosis for rearterialization in orthotopic liver transplantation in rats.| | View in PubMed
- Intracranial pressure monitoring and liver transplantation for fulminant hepatic failure.| | View in PubMed
- Recurrent and acquired hepatitis C viral infection in liver transplant recipients.| | View in PubMed
- Hepatitis B virus and apparent fulminant non-A, non-B hepatitis.| | View in PubMed
- Cell subsets responding to purified hepatocytes and evidence of indirect recognition of hepatocyte major histocompatibility complex class I antigen. I. The role of L3T4+ T cells in the development of allospecific cytotoxicity in hepatocyte-sponge matrix a| | View in PubMed
- Cell subsets responding to purified hepatocytes and evidence of indirect recognition of hepatocyte major histocompatibility complex class I antigen. II. In vitro-generated "memory" cells to class I+ class II- hepatocytes.| | View in PubMed
- Using transjugular intrahepatic portosystemic shunts to control variceal bleeding before liver transplantation.| | View in PubMed
- Intragraft cytokine profile during human liver allograft rejection.| | View in PubMed
- Maintenance immunosuppression after liver transplantation.| | View in PubMed
- The potential supply of organ donors. An assessment of the efficacy of organ procurement efforts in the United States.| | View in PubMed
- Anesthetic care of patients with Crigler-Najjar syndrome.| | View in PubMed
- Efficacy and toxicity of FK 506 for the treatment of resistant rejection in liver transplant patients.| | View in PubMed
- Similar clinical presentation of neurotoxicity following FK 506 and cyclosporine in a liver transplant recipient.| | View in PubMed
- Azathioprine hepatotoxicity after liver transplantation.| | View in PubMed
- Histopathologic study of transjugular intrahepatic portosystemic shunts.| | View in PubMed
- Evidence for direct and indirect pathways in the generation of the alloimmune response against pancreatic islets.| | View in PubMed
- Demonstration of local immunosuppression with methylprednisolone in the sponge matrix allograft model.| | View in PubMed
- Graft vs. host disease after liver transplantation in humans: a report of four cases.| | View in PubMed
- Hepatitis C virus not found in fulminant non-A, non-B hepatitis.| | View in PubMed
- Early liver transplantation is indicated for tyrosinemia type I.| | View in PubMed
- Intrahepatic portocaval shunt for variceal hemorrhage prior to liver transplantation.| | View in PubMed
- Cladosporium trichoides cerebral phaeohyphomycosis in a liver transplant recipient. Report of a case.| | View in PubMed
- Hepatitis C in patients undergoing liver transplantation.| | View in PubMed
- Allogeneic hepatocytes stimulate the production of immunoregulatory molecules in mixed lymphocyte hepatocyte cultures.| | View in PubMed
- An improved method for the detection of soluble interleukin 2 receptors in liver transplant recipients by flow cytometry.| | View in PubMed
- Characterization of a cyclosporine-containing liposome.| | View in PubMed
- Comparison of ELISA and a flow cytometric method in the daily monitoring of soluble interleukin 2 receptors in liver transplant recipients.| | View in PubMed
- Comparison of three regimens for cytomegalovirus prophylaxis in 147 liver transplant recipients.| | View in PubMed
- Hepatitis C in liver transplant recipients.| | View in PubMed
- Lack of class II antigen expression on hepatocytes profoundly affects CTL development in vitro and in vivo.| | View in PubMed
- MHC expression on human hepatocytes before and after isolation.| | View in PubMed
- The alloimmune response against pancreatic islets is generated by both direct and indirect pathways.| | View in PubMed
- Persistent hepatitis B virus following interferon alfa therapy and liver transplantation.| | View in PubMed
- Percutaneous transhepatic portal vein angioplasty and stent placement after liver transplantation: early experience.| | View in PubMed
- Examination of vascular anastomoses during liver transplantation by intraoperative Doppler duplex scanning.| | View in PubMed
- Role of macrophages in the immune response to hepatocytes.| | View in PubMed
- Liver transplantation for severe Amanita phalloides mushroom poisoning.| | View in PubMed
- The management of T tube leaks in orthotopic liver transplant recipients with endoscopically placed nasobiliary catheters.| | View in PubMed
- The alloimmune response to murine islets occurs via indirect antigen presentation to LYT2+ and L3T4+ lymphocytes.| | View in PubMed
- Comparison of in vivo and in vitro immune response to purified hepatocytes.| | View in PubMed
- Massive venous air embolism during orthotopic liver transplantation.| | View in PubMed
- Local prednisolone infusion of canine renal allografts.| | View in PubMed
- The pharmacokinetic advantage of local 6-mercaptopurine infusion in a canine renal transplant model.| | View in PubMed
- Transplant renal artery stenosis.| | View in PubMed
- Gastric bezoar after hepatic transplantation.| | View in PubMed
- Liver transplantation in a patient with protoporphyria.| | View in PubMed
- Hemodynamic changes on clamping and unclamping of major vessels during liver transplantation.| | View in PubMed
- Selection criteria for liver transplantation donors.| | View in PubMed
- Modulation of MHC class I antigen decreases pancreatic islet immunogenicity.| | View in PubMed
- Biliary complications after liver transplantation in children.| | View in PubMed
- Adult kidney retransplantation: evolution of treatment and results over 25 years at the University of Minnesota.| | View in PubMed
- Comparative in vitro immunogenicity of cultured murine islets and hepatocytes.| | View in PubMed
- Factors influencing early survival after liver transplantation.| | View in PubMed
- Frequency of precursor cytotoxic T lymphocytes correlates with outcome following heart-lung and pancreatic islet transplantation.| | View in PubMed
- Hereditary tyrosinemia type I (chronic form): pathologic findings in the liver.| | View in PubMed
- In vitro immunosuppressive effects of murine hepatocyte cytosol.| | View in PubMed
- L3T4+,LyT2- and LyT2+,L3T4- T cells participate in the generation of allospecific cytotoxicity in response to MHC class I+ hepatocytes.| | View in PubMed
- Long-term outcome of renal transplantation in patients with systemic lupus erythematosus.| | View in PubMed
- Pediatric liver transplantation across ABO blood group barriers.| | View in PubMed
- Rapid infusion technique as a safe alternative to veno-venous bypass in orthotopic liver transplant (TX).| | View in PubMed
- Afferent and efferent pathways in T cell responses to MHC class I+, II-hepatocytes.| | View in PubMed
- Effect of immunodepletion of MHC class II-positive cells from pancreatic islets on generation of cytotoxic T-lymphocytes in mixed islet-lymphocyte coculture.| | View in PubMed
- Generation of allospecific cytolytic T-lymphocytes stimulated by pure pancreatic beta-cells in absence of Ia+ dendritic cells.| | View in PubMed
- Liver transplantation today.| | View in PubMed
- Pharmacokinetics of 6-thiouric acid and 6-mercaptopurine in renal allograft recipients after oral administration of azathioprine.| | View in PubMed
- Responder T-cell subsets and antigenic stimulus in mixed lymphocyte-hepatocyte culture.| | View in PubMed
- An implantable pump for intrarenal infusion of immunosuppressants in a canine autotransplant model.| | View in PubMed
- Infection and rejection of primary hepatic transplant in 93 consecutive patients treated with triple immunosuppressive therapy.| | View in PubMed
- Orthotopic liver transplantation: nonoperative management of early, acute portal vein thrombosis.| | View in PubMed
- Single-center 1-15-year results of renal transplantation in patients with systemic lupus erythematosus.| | View in PubMed
- [Comparison of the results of liver transplantation in children and adults].| | View in PubMed
- Couette membrane filtration with constant shear stress.| | View in PubMed
- In vitro generated allospecific cytolytic T lymphocytes injure pancreatic islets.| | View in PubMed
- A single-center experience of renal transplantation in thirteen Jehovah's Witnesses.| | View in PubMed
- Adjunctive azathioprine and antilymphocyte serum immunosuppression with cyclosporine.| | View in PubMed
- Effects of HLA matching in cadaver renal transplants.| | View in PubMed
- Erythrocytosis and thromboembolic complications after renal transplantation: results from a randomized trial of cyclosporine versus azathioprine-antilymphocyte globulin.| | View in PubMed
- Imaging of vascular complications after hepatic transplantation.| | View in PubMed
- Biliary complications after liver transplantation in patients with preexisting sclerosing cholangitis.| | View in PubMed
- Pancreatic islets generate allospecific cytolytic T lymphocytes in a mixed lymphocyte-islet culture.| | View in PubMed
- Imaging of renal transplants.| | View in PubMed
- Lymphocyte traffic and distribution after sponge matrix allograft using limiting dilution analysis.| | View in PubMed
- The contribution of natural killer cells to the allograft response.| | View in PubMed
- Characterization of natural killer activity in sponge matrix allografts.| | View in PubMed
- A randomized trial comparing cyclosporine with antilymphoblast-globulin-azathioprine for renal allograft recipients. Results at 2 1/2-6 years.| | View in PubMed
- Failure of freshly inplanted alloantigen in vivo to attract circulating allosensitized lymphocytes.| | View in PubMed
- ABO-compatible mismatching decreases 5-year actuarial graft survival after renal transplantation.| | View in PubMed
- Thromboembolic complications in renal allograft recipients. A report from the prospective randomized study of cyclosporine versus azathioprine-antilymphocyte globulin.| | View in PubMed
- Mixed islet-lymphocyte culture as a model for pancreatic islet immunogenicity and cell-mediated immune injury.| | View in PubMed
- Suppression of macrophage-mediated lymphocyte recruitment by local but not systemic steroids.| | View in PubMed
- The impact of cyclosporine and combination immunosuppression on the incidence of posttransplant diabetes in renal allograft recipients.| | View in PubMed
- Abdominal sonography after hepatic transplantation: results in 36 patients.| | View in PubMed
- Hepatic regenerating nodules in hereditary tyrosinemia.| | View in PubMed
- Major histocompatibility complex class I antigens on hepatocytes in human liver grafts.| | View in PubMed
- Pediatric liver transplantation using combination immunosuppressive therapy.| | View in PubMed
- Reperfusion coagulopathy during human liver transplantation.| | View in PubMed
- Liver allograft transplantation: postoperative CT findings.| | View in PubMed
- Hepatitis-associated aplastic anemia after liver transplantation.| | View in PubMed
- Kidney transplantation in diabetic patients.| | View in PubMed
- Contribution of extrahepatic tissues to biochemical abnormalities in hereditary tyrosinemia type I: study of three patients after liver transplantation.| | View in PubMed
- Ultrasound and computed tomographic evaluation in hepatic transplantation.| | View in PubMed
- An analysis of histological prognostic features of liver allograft rejection based on 270 serial biopsies.| | View in PubMed
- Can renal transplantation be done safely without prior dialysis therapy?| | View in PubMed
- Class I major histocompatibility complex antigens are induced on hepatocytes in rejecting human liver grafts.| | View in PubMed
- Cloned T cells do not require host H-2 restrictions to elicit delayed-type hypersensitivity.| | View in PubMed
- Compartmentalization and lymphocyte traffic after allograft challenge.| | View in PubMed
- Cox regression analysis of outcome risk factors in 519 renal allograft recipients.| | View in PubMed
- Designation of liver transplant centers in the United States.| | View in PubMed
- Detrimental effect of ABO mismatching in renal transplantation.| | View in PubMed
- Effector mechanisms in allograft rejection.| | View in PubMed
- First kidney transplants in children 5 years of age or younger.| | View in PubMed
- Frequency of diabetes-related complications in renal allograft recipients prospectively randomized to cyclosporine or azathioprine.| | View in PubMed
- HLA-DR tissue typing may be ignored for first but not subsequent cadaver renal transplants.| | View in PubMed
- In vivo macrophage-directed lymphocyte traffic requires macrophage activation.| | View in PubMed
- Plasma amino acid clearance predicts hepatic recovery after normothermic anoxia and cold preservation.| | View in PubMed
- Prognostic perioperative factors predicting the outcome of liver transplantation.| | View in PubMed
- Purified hepatocytes can stimulate allospecific cytolytic T lymphocytes in a mixed lymphocyte-hepatocyte culture.| | View in PubMed
- Renal allograft survival in patients with positive donor-specific B lymphocyte crossmatches.| | View in PubMed
- The role of natural killer cells in the allograft response.| | View in PubMed
- Thromboembolic complications after renal transplantation: results from the randomized trial of cyclosporine v azathioprine-antilymphocyte globulin.| | View in PubMed
- Use of triple therapy and percutaneous needle biopsy to minimize graft failure following liver transplantation.| | View in PubMed
- Increased expression of class I major histocompatibility complex antigens on hepatocytes in rejecting human liver allografts.| | View in PubMed
- Liver allograft rejection. An analysis of the use of biopsy in determining outcome of rejection.| | View in PubMed
- Renal transplantation done safely without prior chronic dialysis therapy.| | View in PubMed
- MR evaluation of the portal vein in pediatric liver transplant candidates.| | View in PubMed
- The outcome of 304 primary renal transplants in children (1968-1985).| | View in PubMed
- Lymphocytes capable of mediating delayed-type hypersensitivity reactions accumulate within sponge matrix allografts.| | View in PubMed
- Current results in pediatric renal transplantation at the University of Minnesota.| | View in PubMed
- Fulminant Wilson's disease treated with postdilution hemofiltration and orthotopic liver transplantation.| | View in PubMed
- Early and late effects of two immunosuppressive drug protocols on recipients of renal allografts: results of the Minnesota randomized trial comparing cyclosporine versus antilymphocyte globulin-azathioprine.| | View in PubMed
- New immunosuppressive drug combinations for mismatched related and cadaveric renal transplantation.| | View in PubMed
- Renal transplant immunity and immunosuppression.| | View in PubMed
- Scintigraphic evaluation of liver transplant function.| | View in PubMed
- The effects of delayed function on recipients of cadaver renal allografts. A study of 158 patients randomized to cyclosporine or ALG-azathioprine.| | View in PubMed
- The migration of activated T lymphocytes in vitro. III. Paralysis and recovery of locomotor function during mitosis.| | View in PubMed
- Alterations in amino acid clearance during ischemia predict hepatocellular ATP changes.| | View in PubMed
- Management and prevention of cyclosporine nephrotoxicity after renal transplantation: use of low doses of cyclosporine, azathioprine, and prednisone.| | View in PubMed
- Results of the Minnesota randomized prospective trial of cyclosporine versus azathioprine-antilymphocyte globulin for immunosuppression in renal allograft recipients.| | View in PubMed
- A single institution, randomized, prospective trial of cyclosporin versus azathioprine-antilymphocyte globulin for immunosuppression in renal allograft recipients.| | View in PubMed
- Information and long-term follow-up of a large number of related kidney donors at a single institution.| | View in PubMed
- Persistent succinylacetone excretion after liver transplantation in a patient with hereditary tyrosinaemia type I.| | View in PubMed
- Studies on living related kidney donors at a single institution.| | View in PubMed
- A functional assay for cyclosporine in patient serum.| | View in PubMed
- Comparison of modes of action of different immunosuppressive agents.| | View in PubMed
- Long-term effect of splenectomy versus no splenectomy in renal transplant patients. Reanalysis of a randomized prospective study.| | View in PubMed
- Similar renal allograft functional survival rates for kidneys from sibling donors matched for zero-versus-one haplotype with the recipient.| | View in PubMed
- Liver transplantation.| | View in PubMed
- Orthotopic liver transplantation: a pathological study of 63 serial liver biopsies from 17 patients with special reference to the diagnostic features and natural history of rejection.| | View in PubMed
- Survival rates of 2,728 patients with end-stage renal disease.| | View in PubMed
- Metabolism during hepatic transplantation: indicators of allograft function.| | View in PubMed
- Results of renal transplantation in diabetics at the University of Minnesota since 1979, including a comparison of outcome in diabetic and nondiabetic recipients randomized to cyclosporine versus azathioprine for immunosuppression.| | View in PubMed
- Comparison of azathioprine-antilymphocyte globulin versus cyclosporine in renal transplantation.| | View in PubMed
- Hepatic transplantation and biliary atresia: early experience in eight patients.| | View in PubMed
- Cellular basis of allograft rejection.| | View in PubMed
- Cyclosporine immunosuppression.| | View in PubMed
- Maturation of cytotoxic T cells within sponge matrix allografts.| | View in PubMed
- The community physician and liver transplantation.| | View in PubMed
- The migration of activated murine T lymphocytes in vitro. II. Evidence for differential locomotion of T cell subsets.| | View in PubMed
- Cellular events within the rejecting allograft.| | View in PubMed
- Maturation of cytotoxic effector cells at the site of allograft rejection.| | View in PubMed
- Migration of mouse lymphocytes in vitro. I. Normal lymph node lymphocytes.| | View in PubMed
- Migratory behavior of lymphocytes during allograft rejection.| | View in PubMed
- Evidence for local helper and suppressor function at the site of allograft rejection.| | View in PubMed
- Radiolabeled autologous leukocyte scanning in abscess detection.| | View in PubMed
- Specific and nonspecific infiltration of sponge matrix allografts by specifically sensitized cytotoxic lymphocytes.| | View in PubMed
- Effects of HLA-A and B matching on success of cadaver grafts at a single center.| | View in PubMed
- Epstein-Barr virus antibody responses and clinical illness in renal transplant recipients.| | View in PubMed
- Indium 111 autologous tagged leukocytes in the diagnosis of intraperitoneal sepsis.| | View in PubMed
- Partial characterization of cytotoxic cells infiltrating sponge matrix allografts.| | View in PubMed
- Causes and management of rejection.| | View in PubMed
- Relative absence of helper cells in rejecting allografts.| | View in PubMed
- 100 HLA-identical sibling transplants. Prognostic factors other than histocompatibility.| | View in PubMed
- 100 second renal allografts from a single transplantation institution.| | View in PubMed
- Graft rejection in donor-recipient pairs with differing of H-2 loci.| | View in PubMed
- Local graft irradiation: effect on cytotoxic cell infiltration.| | View in PubMed
- Jaundice after renal allotransplantation.| | View in PubMed
- Tuberculous joint disease in transplant patients.| | View in PubMed
- Listeria infection in transplant patients. Five cases and a review of the literature.| | View in PubMed
- Superior results of well matched cadaveric grafts as compared to parental grafts.| | View in PubMed
- Cryopreservation of vein grafts.| | View in PubMed