University of California San Francisco

Dr. Tobias Deuse
Tobias Deuse, MD

Professor of Surgery
Division of Cardiothoracic Surgery
The Julien I.E. Hoffman, M.D. Endowed Chair in Cardiac Surgery
Director, Minimally-invasive Cardiac Surgery
Surgical Director, Transcatheter Valve Program

Academic Office:
500 Parnassus Ave, MUW 405, Box 0118
San Francisco, CA 94143-0118
Tel: (415) 353-8890
Email: [email protected] 
Admin: [email protected] 

Cardiac Surgery Program
400 Parnassus Avenue, Suite 501, Box 0957
San Francisco, California,  94143
Tel:415-353-1606
Fax: 415-353-1312

    Biography

    Dr. Tobias Deuse is a heart surgeon and the director of minimally invasive cardiac surgery at UCSF. He is known for his pioneering work in developing minimally invasive techniques for mitral valve repair. Deuse earned his medical degree from the University of Würzburg in Germany. He received advanced training in heart and lung surgery at the University Hospital of Munich and University Heart Center Hamburg. After obtaining board certification in Germany as a heart surgeon, he completed a fellowship in lung and heart-lung transplantation with Stanford Medicine. After returning to Germany in 2009, Deuse was appointed director of heart and lung transplantation at the University Heart Center Hamburg. He achieved international acclaim for his development of innovative approaches to heart failure surgery, most notably minimally invasive techniques for implanting ventricular assist systems. He also demonstrated that high success rates could be achieved in mitral valve repair utilizing fully robot-assisted endoscopic surgery. Also known as keyhole surgery, this approach has many benefits for the patient, including substantially reduced postsurgical pain, shorter hospital stays and faster recovery. Deuse has received numerous honors, including election to the board of directors of the International Society for Heart and Lung Transplantation.

    Education

    Institution Degree Dept or School End Date
    University of California Diversity, Equity, and Inclusion Champion Training 2019

    Collaboration Interests

    I am interested in:

    • PhysicianScientist

    Clinical Expertise

    Minimally Invasive Mitral Valve Surgery

    Minimally Invasive Aortic Valve Surgery

    Minimally Invasive Atrial Septal Defect (ASD) Closure

    Aortic Valve Repair & Replacement

    Acute Aortic Dissection Repair

    Heart Transplantation

    Lung Transplantation

    Ventricular Assist Devices (VAD)

    Ventricular Aneurysm

    Arrhythmia

    Coronary Artery Bypass Grafting (CABG)

    Off-Pump Coronary Artery Bypass (OPCAB)

    Foreign Languages Spoken

    German

    Program Affiliations

    UCSF Heart & Vascular Center

    Grants and Funding

    • Hypo-immunogenic cardiomyocytes for myocardial repair | NIH | 2018-08-01 - 2022-06-30 | Role: Principal Investigator
    • Microgravity as model for immunological senescence and its impact on tissue stem cells and regeneration | NIH | 2017-06-15 - 2022-06-30 | Role: Co-Principal Investigator
    • Microgravity as model for immunological senescence and its impact on tissue stem cells and regeneration | NIH | 2017-06-15 - 2020-02-29 | Role: Co-Principal Investigator

    Research Narrative

    Dr. Deuse's research is focused on vascular biology and pathophysiology. His group was the among the first to elucdiate the novel pathways involved in the development of vascular intimal hyperplasia. Myointimal hyperplasia is a pathological process of the vascular system characterized by abnormal proliferation of smooth muscle cells of the vascular wall that leads to luminal obliteration and subsequent ischemia.

    Myointimal hyperplasia may occur in patients after vessel injury during medical procedures (e.g. after balloon dilation or stent placement) or after pathological injury of the blood vessel (e.g. due to inflammation or toxic exposure). It can cause bypass graft failure and in-stent restenosis. To help prevent this and increase the success of treatments for vascular disease including coronary heart disease, his research group is working on the development of new preventive drug regimes and strategies.

    Research Interests

    Vascular Biology

    Stem Cell Immunobiology

    Transplant Immunology

    Oxidative Stress and Apoptosis

    Pulmonary Hypertension

    Publications

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 139
    1. Hypoimmune islets achieve insulin independence after allogeneic transplantation in a fully immunocompetent non-human primate.
      Hu X, White K, Young C, Olroyd AG, Kievit P, Connolly AJ, Deuse T, Schrepfer S| | View in PubMed
    2. Four Decades of Progress in Heart-Lung Transplantation: 271 Cases at a Single Institution.
      Elde S, Baccouche BM, Mullis DM, Leipzig MM, Deuse T, Krishnan A, Fawad M, Dale R, Walsh S, Padilla-Lopez A, Wesley B, He H, Yajima S, Zhu Y, Wang H, Guenthart BA, Shudo Y, Reitz BA, Woo YJ| | View in PubMed
    3. Lung Transplantation in Patients with Cystic Fibrosis: A Complex Task, A Changing Target.
      Loebe M, Deuse T, Sinha N, Koster A, Erdoes G| | View in PubMed
    4. Synthetic immune checkpoint engagers protect HLA-deficient iPSCs and derivatives from innate immune cell cytotoxicity.
      Gravina A, Tediashvili G, Zheng Y, Iwabuchi KA, Peyrot SM, Roodsari SZ, Gargiulo L, Kaneko S, Osawa M, Schrepfer S, Deuse T| | View in PubMed
    5. Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques.
      Hu X, White K, Olroyd AG, DeJesus R, Dominguez AA, Dowdle WE, Friera AM, Young C, Wells F, Chu EY, Ito CE, Krishnapura H, Jain S, Ankala R, McGill TJ, Lin A, Egenberger K, Gagnon A, Michael Rukstalis J, Hogrebe NJ, Gattis C, Basco R, Millman JR, Kievit P, Davis MM, Lanier LL, Connolly AJ, Deuse T, Schrepfer S| | View in PubMed
    6. Human hypoimmune primary pancreatic islets avoid rejection and autoimmunity and alleviate diabetes in allogeneic humanized mice.
      Hu X, Gattis C, Olroyd AG, Friera AM, White K, Young C, Basco R, Lamba M, Wells F, Ankala R, Dowdle WE, Lin A, Egenberger K, Rukstalis JM, Millman JR, Connolly AJ, Deuse T, Schrepfer S| | View in PubMed
    7. Hypoimmune anti-CD19 chimeric antigen receptor T cells provide lasting tumor control in fully immunocompetent allogeneic humanized mice.
      Hu X, Manner K, DeJesus R, White K, Gattis C, Ngo P, Bandoro C, Tham E, Chu EY, Young C, Wells F, Basco R, Friera A, Kangeyan D, Beauchesne P, Dowdle WE, Deuse T, Fry TJ, Foster AE, Schrepfer S| | View in PubMed
    8. Protection of cell therapeutics from antibody-mediated killing by CD64 overexpression.
      Gravina A, Tediashvili G, Rajalingam R, Quandt Z, Deisenroth C, Schrepfer S, Deuse T| | View in PubMed
    9. Morbidity and Mortality Associated With Blood Transfusions in Elective Adult Cardiac Surgery.
      Sanaiha Y, Hadaya J, Verma A, Shemin RJ, Madani M, Young N, Deuse T, Sun J, Benharash P, University of California Cardiac Surgery Consortium| | View in PubMed
    10. Author Correction: Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients.
      Deuse T, Hu X, Gravina A, Wang D, Tediashvili G, De C, Thayer WO, Wahl A, Garcia JV, Reichenspurner H, Davis MM, Lanier LL, Schrepfer S| | View in PubMed
    11. Intercostal Nerve Cryoanalgesia Versus Thoracic Epidural Analgesia in Lung Transplantation: A Retrospective Single-Center Study.
      Isaza E, Santos J, Haro GJ, Chen J, Weber DJ, Deuse T, Singer JP, Golden JA, Hays S, Trinh BN, Brzezinski M, Kukreja J| | View in PubMed
    12. Hypoimmune induced pluripotent stem cell-derived cell therapeutics treat cardiovascular and pulmonary diseases in immunocompetent allogeneic mice.
      Deuse T, Tediashvili G, Hu X, Gravina A, Tamenang A, Wang D, Connolly A, Mueller C, Mallavia B, Looney MR, Alawi M, Lanier LL, Schrepfer S| | View in PubMed
    13. Shock, Thrombus, TAVR: A Challenging TAVR With Large Left-Ventricular Thrombus.
      Blusztein D, Teng P, Deuse T, Mahadevan VS| | View in PubMed
    14. Immunomodulation Therapy Using Tolerogenic Macrophages in a Rodent Model of Pulmonary Hypertension.
      Guihaire J, Deuse T, Wang D, Spin JM, Blankenberg FG, Fadel E, Reichenspurner H, Schrepfer S| | View in PubMed
    15. The SIRPα-CD47 immune checkpoint in NK cells.
      Deuse T, Hu X, Agbor-Enoh S, Jang MK, Alawi M, Saygi C, Gravina A, Tediashvili G, Nguyen VQ, Liu Y, Valantine H, Lanier LL, Schrepfer S| | View in PubMed
    16. Outcomes of transcatheter aortic valve replacement in end stage liver and renal disease.
      Caughron H, Parikh D, Allison Z, Deuse T, Mahadevan VS| | View in PubMed
    17. Subxiphoid Hybrid Epicardial-Endocardial Atrial Fibrillation Ablation and LAA Ligation: Initial Sub-X Hybrid MAZE Registry Results.
      Ellis CR, Badhwar N, Tschopp D, Danter M, Jackson GG, Kerendi F, Walters T, Fang Q, Deuse T, Beygui R, Lee RJ| | View in PubMed
    18. Impact of Aortic Stenosis on Myofiber Stress: Translational Application of Left Ventricle-Aortic Coupling Simulation.
      Wisneski AD, Wang Y, Deuse T, Hill AC, Pasta S, Sack KL, Yao J, Guccione JM| | View in PubMed
    19. The H-Y Antigen in Embryonic Stem Cells Causes Rejection in Syngeneic Female Recipients.
      Hu X, Kueppers ST, Kooreman NG, Gravina A, Wang D, Tediashvili G, Schlickeiser S, Frentsch M, Nikolaou C, Thiel A, Marcus S, Fuchs S, Velden J, Reichenspurner H, Volk HD, Deuse T, Schrepfer S| | View in PubMed
    20. Risk Factors and Outcomes of Extracorporeal Membrane Oxygenation as a Bridge to Lung Transplantation.
      Kukreja J, Tsou S, Chen J, Trinh BN, Feng C, Golden JA, Hays S, Deuse T, Singer JP, Brzezinski M| | View in PubMed
    21. Frailty after lung transplantation is associated with impaired health-related quality of life and mortality.
      Venado A, Kolaitis NA, Huang CY, Gao Y, Glidden DV, Soong A, Sutter N, Katz PP, Greenland JR, Calabrese DR, Hays SR, Golden JA, Shah RJ, Leard LE, Kukreja J, Deuse T, Wolters PJ, Covinsky K, Blanc PD, Singer JP| | View in PubMed
    22. Impact of donor lung quality on post-transplant recipient outcome in the Lung Allocation Score era in Eurotransplant - a historical prospective study.
      Smits JM, Gottlieb J, Verschuuren E, Evrard P, Hoek R, Knoop C, Lang G, Kwakkel-van Erp JM, Vos R, Verleden G, Rondelet B, Hoefer D, Langer F, Schramm R, Hoetzenecker K, van Kessel D, Luijk B, Seghers L, Deuse T, Buhl R, Witt C, Strelniece A, Green D, de Vries E, Laufer G, Van Raemdonck D| | View in PubMed
    23. A Cryoinjury Model to Study Myocardial Infarction in the Mouse.
      Wang D, Tediashvili G, Hu X, Gravina A, Marcus SG, Zhang H, Olgin JE, Deuse T, Schrepfer S| | View in PubMed
    24. De novo mutations in mitochondrial DNA of iPSCs produce immunogenic neoepitopes in mice and humans.
      Deuse T, Hu X, Agbor-Enoh S, Koch M, Spitzer MH, Gravina A, Alawi M, Marishta A, Peters B, Kosaloglu-Yalcin Z, Yang Y, Rajalingam R, Wang D, Nashan B, Kiefmann R, Reichenspurner H, Valantine H, Weissman IL, Schrepfer S| | View in PubMed
    25. Bergeyella cardium: Clinical Characteristics and Draft Genome of an Emerging Pathogen in Native and Prosthetic Valve Endocarditis.
      Mulliken JS, Langelier C, Budak JZ, Miller S, Dynerman D, Hao S, Li LM, Crawford E, Lyden A, Woodworth MH, DeRisi JL, Desmond E, Browne C, Luu A, Grandis DJ, Grossman W, Deuse T, Melcher GP| | View in PubMed
    26. Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients.
      Deuse T, Hu X, Gravina A, Wang D, Tediashvili G, De C, Thayer WO, Wahl A, Garcia JV, Reichenspurner H, Davis MM, Lanier LL, Schrepfer S| | View in PubMed
    27. Nontyphoidal Salmonella as a Cause of Mediastinal Abscess after Aortic Valve Replacement: A Case Report and Review of Postoperative Salmonella Infections.
      Spottiswoode N, Peluso MJ, Deuse T, Babik JM| | View in PubMed
    28. Analysis of Minimally Invasive Left Thoracotomy HVAD Implantation - A Single-Center Experience.
      Reichart D, Brand CF, Bernhardt AM, Schmidt S, Schaefer A, Blankenberg S, Reichenspurner H, Wagner FM, Deuse T, Barten MJ| | View in PubMed
    29. Lung allocation score: the Eurotransplant model versus the revised US model - a cross-sectional study.
      Smits JM, Nossent G, Evrard P, Lang G, Knoop C, Kwakkel-van Erp JM, Langer F, Schramm R, van de Graaf E, Vos R, Verleden G, Rondelet B, Hoefer D, Hoek R, Hoetzenecker K, Deuse T, Strelniece A, Green D, de Vries E, Samuel U, Laufer G, Buhl R, Witt C, Gottlieb J| | View in PubMed
    30. Normothermic ex-vivo preservation with the portable Organ Care System Lung device for bilateral lung transplantation (INSPIRE): a randomised, open-label, non-inferiority, phase 3 study.
      Warnecke G, Van Raemdonck D, Smith MA, Massard G, Kukreja J, Rea F, Loor G, De Robertis F, Nagendran J, Dhital KK, Moradiellos Díez FJ, Knosalla C, Bermudez CA, Tsui S, McCurry K, Wang IW, Deuse T, Lesèche G, Thomas P, Tudorache I, Kühn C, Avsar M, Wiegmann B, Sommer W, Neyrinck A, Schiavon M, Calabrese F, Santelmo N, Olland A, Falcoz PE, Simon AR, Varela A, Madsen JC, Hertz M, Haverich A, Ardehali A| | View in PubMed
    31. Hybrid Open Minimally Invasive Transcatheter Mitral Valve Replacement.
      Marcus SG, Mahadevan VS, Deuse T| | View in PubMed
    32. Balloon-based Injury to Induce Myointimal Hyperplasia in the Mouse Abdominal Aorta.
      Tediashvili G, Wang D, Reichenspurner H, Deuse T, Schrepfer S| | View in PubMed
    33. Hybrid and surgical procedures for the treatment of persistent and longstanding persistent atrial fibrillation.
      Sanchez JM, Al-Dosari G, Chu S, Beygui R, Deuse T, Badhwar N, Lee RJ| | View in PubMed
    34. Outcomes of Minimally Invasive Temporary Right Ventricular Assist Device Support for Acute Right Ventricular Failure During Minimally Invasive Left Ventricular Assist Device Implantation.
      Schaefer A, Reichart D, Bernhardt AM, Kubik M, Barten MJ, Wagner FM, Reichenspurner H, Philipp SA, Deuse T| | View in PubMed
    35. Thalidomide treatment prevents chronic graft rejection after aortic transplantation in rats - an experimental study.
      Miller KK, Wang D, Hu X, Hua X, Deuse T, Neofytou E, Renne T, Velden J, Reichenspurner H, Schrepfer S, Bernstein D| | View in PubMed
    36. Differences in Vascular Response between Balloon Overstretch and Stent Overexpansion in Nonatherosclerotic Porcine Coronary Arteries.
      Mitsutake Y, Reifart J, Pyun WB, Lyons JK, Deuse T, Schrepfer S, Ikeno F| | View in PubMed
    37. Gender differences and outcomes in left ventricular assist device support: The European Registry for Patients with Mechanical Circulatory Support.
      Magnussen C, Bernhardt AM, Ojeda FM, Wagner FM, Gummert J, de By TMMH, Krabatsch T, Mohacsi P, Rybczynski M, Knappe D, Sill B, Deuse T, Blankenberg S, Schnabel RB, Reichenspurner H| | View in PubMed
    38. The value of fluorine-18 deoxyglucose positron emission tomography scans in patients with ventricular assist device specific infections†.
      Bernhardt AM, Pamirsad MA, Brand C, Reichart D, Tienken M, Barten MJ, Schaefer A, Grahn H, Rybczynski M, Deuse T, Reichenspurner H, Wagner FM| | View in PubMed
    39. Lobar lung transplantation from deceased donors: A systematic review.
      Eberlein M, Reed RM, Chahla M, Bolukbas S, Blevins A, Van Raemdonck D, Stanzi A, Inci I, Marasco S, Shigemura N, Aigner C, Deuse T| | View in PubMed
    40. Vein Interposition Model: A Suitable Model to Study Bypass Graft Patency.
      Wang D, Tediashvili G, Pecha S, Reichenspurner H, Deuse T, Schrepfer S| | View in PubMed
    41. Orthotopic tracheal transplantation using human bronchus: an original xenotransplant model of obliterative airway disorder.
      Guihaire J, Itagaki R, Stubbendorff M, Hua X, Deuse T, Ullrich S, Fadel E, Dorfmüller P, Robbins RC, Reichenspurner H, Schumacher U, Schrepfer S| | View in PubMed
    42. Acute Pulmonary Artery Obstruction as the Primary Manifestation of a Rapidly Growing Intimal Sarcoma in a 54-Year-Old Patient.
      Westhofen S, Kugler C, Reichenspurner H, Deuse T| | View in PubMed
    43. A matched pairs analysis of non-rib-spreading, fully endoscopic, mini-incision technique versus conventional mini-thoracotomy for mitral valve repair.
      Westhofen S, Conradi L, Deuse T, Detter C, Vettorazzi E, Treede H, Reichenspurner H| | View in PubMed
    44. The Selective JAK1/3-Inhibitor R507 Mitigates Obliterative Airway Disease Both With Systemic Administration and Aerosol Inhalation.
      Deuse T, Hua X, Stubbendorff M, Spin JM, Neofytou E, Taylor V, Chen Y, Park G, Fink JB, Renne T, Kiefmann M, Kiefmann R, Reichenspurner H, Robbins RC, Schrepfer S| | View in PubMed
    45. The MANDELA study: A multicenter, randomized, open-label, parallel group trial to refine the use of everolimus after heart transplantation.
      Deuse T, Bara C, Barten MJ, Hirt SW, Doesch AO, Knosalla C, Grinninger C, Stypmann J, Garbade J, Wimmer P, May C, Porstner M, Schulz U| | View in PubMed
    46. Sex Differences in Immunology: More Severe Development of Experimental Pulmonary Hypertension in Male Rats Exposed to Vascular Endothelial Growth Factor Receptor Blockade.
      Guihaire J, Deuse T, Wang D, Fadel E, Reichenspurner H, Schrepfer S| | View in PubMed
    47. Distal Airway Stem Cells are Essential for Lung Regeneration.
      Deuse T, Schrepfer S| | View in PubMed
    48. Local MicroRNA Modulation Using a Novel Anti-miR-21-Eluting Stent Effectively Prevents Experimental In-Stent Restenosis.
      Wang D, Deuse T, Stubbendorff M, Chernogubova E, Erben RG, Eken SM, Jin H, Li Y, Busch A, Heeger CH, Behnisch B, Reichenspurner H, Robbins RC, Spin JM, Tsao PS, Schrepfer S, Maegdefessel L| | View in PubMed
    49. Mesenchymal stromal cell therapy: different sources exhibit different immunobiological properties.
      Neofytou E, Deuse T, Beygui RE, Schrepfer S| | View in PubMed
    50. Immunobiology of fibrin-based engineered heart tissue.
      Conradi L, Schmidt S, Neofytou E, Deuse T, Peters L, Eder A, Hua X, Hansen A, Robbins RC, Beygui RE, Reichenspurner H, Eschenhagen T, Schrepfer S| | View in PubMed
    51. Concomitant minimally invasive HVAD and transapical aortic valve implantation.
      Schaefer A, Treede H, Bernhardt A, Wagner FM, Reichenspurner H, Deuse T| | View in PubMed
    52. SCNT-derived ESCs with mismatched mitochondria trigger an immune response in allogeneic hosts.
      Deuse T, Wang D, Stubbendorff M, Itagaki R, Grabosch A, Greaves LC, Alawi M, Grünewald A, Hu X, Hua X, Velden J, Reichenspurner H, Robbins RC, Jaenisch R, Weissman IL, Schrepfer S| | View in PubMed
    53. Thymoglobulin induction in heart transplantation: patient selection and implications for maintenance immunosuppression.
      Zuckermann A, Schulz U, Deuse T, Ruhpawar A, Schmitto JD, Beiras-Fernandez A, Hirt S, Schweiger M, Kopp-Fernandes L, Barten MJ| | View in PubMed
    54. Isolated permanent right ventricular assist device implantation with the HeartWare continuous-flow ventricular assist device: first results from the European Registry for Patients with Mechanical Circulatory Support.
      Bernhardt AM, De By TM, Reichenspurner H, Deuse T| | View in PubMed
    55. Clinical experience of combined HeartWare ventricular assist device and implantable cardioverter defibrillator therapy.
      Pecha S, Wilke I, Bernhardt A, Hakmi S, Yildirim Y, Steven D, Reichenspurner H, Willems S, Deuse T, Aydin A| | View in PubMed
    56. HVAD implantation in right atrium-to-right pulmonary artery configuration.
      Deuse T, Kubik M, Reichenspurner H| | View in PubMed
    57. Introduction of the lung allocation score in Germany.
      Gottlieb J, Greer M, Sommerwerck U, Deuse T, Witt C, Schramm R, Hagl C, Strueber M, Smits JM| | View in PubMed
    58. Inducing myointimal hyperplasia versus atherosclerosis in mice: an introduction of two valid models.
      Stubbendorff M, Hua X, Deuse T, Ali Z, Reichenspurner H, Maegdefessel L, Robbins RC, Schrepfer S| | View in PubMed
    59. Dichloroacetate prevents restenosis in preclinical animal models of vessel injury.
      Deuse T, Hua X, Wang D, Maegdefessel L, Heeren J, Scheja L, Bolaños JP, Rakovic A, Spin JM, Stubbendorff M, Ikeno F, Länger F, Zeller T, Schulte-Uentrop L, Stoehr A, Itagaki R, Haddad F, Eschenhagen T, Blankenberg S, Kiefmann R, Reichenspurner H, Velden J, Klein C, Yeung A, Robbins RC, Tsao PS, Schrepfer S| | View in PubMed
    60. Minimally invasive implantation of biventricular assist devices.
      Deuse T, Reichenspurner H| | View in PubMed
    61. Do not touch the sternum--thoracotomy incisions for HVAD implantation.
      Deuse T, Reichenspurner H| | View in PubMed
    62. Efficacy of prophylactic intra-aortic balloon pump therapy in chronic heart failure patients undergoing cardiac surgery.
      Yildirim Y, Pecha S, Kubik M, Alassar Y, Deuse T, Hakmi S, Reichenspurner H| | View in PubMed
    63. Dual-chamber pacemaker implantation with left ventricular pacing in a patient with a right ventricular assist device.
      Sill B, Reichenspurner H, Deuse T| | View in PubMed
    64. HVAD continuous flow assist device for ischemic ventricular septal rupture.
      Bernhardt AM, Reichenspurner H, Deuse T| | View in PubMed
    65. Mechanically induced ventricular tachycardia by the HeartWare ventricular assist device.
      Yildirim Y, Pecha S, Reichenspurner H, Deuse T| | View in PubMed
    66. Everolimus in heart transplantation: an update.
      Hirt SW, Bara C, Barten MJ, Deuse T, Doesch AO, Kaczmarek I, Schulz U, Stypmann J, Haneya A, Lehmkuhl HB| | View in PubMed
    67. Bortezomib rescue therapy in a patient with recurrent antibody-mediated rejection after lung transplantation.
      Baum C, Reichenspurner H, Deuse T| | View in PubMed
    68. Granulocyte colony-stimulating factor therapy is associated with a reduced incidence of acute rejection episodes or allograft vasculopathy in heart transplant recipients.
      Vrtovec B, Haddad F, Pham M, Deuse T, Fearon WF, Schrepfer S, Leon S, Vu T, Valantine H, Hunt SA| | View in PubMed
    69. Immunological properties of extraembryonic human mesenchymal stromal cells derived from gestational tissue.
      Stubbendorff M, Deuse T, Hua X, Phan TT, Bieback K, Atkinson K, Eiermann TH, Velden J, Schröder C, Reichenspurner H, Robbins RC, Volk HD, Schrepfer S| | View in PubMed
    70. Minimal access median sternotomy for aortic valve replacement in elderly patients.
      Alassar Y, Yildirim Y, Pecha S, Detter C, Deuse T, Reichenspurner H| | View in PubMed
    71. Isolated permanent right ventricular assistance using the HVAD continuous-flow pump.
      Deuse T, Schirmer J, Kubik M, Reichenspurner H| | View in PubMed
    72. Aspergillus galactomannan antigen for diagnosis and treatment monitoring in cerebral aspergillosis.
      Soeffker G, Wichmann D, Loderstaedt U, Sobottka I, Deuse T, Kluge S| | View in PubMed
    73. ST-elevation myocardial infarction following heart transplantation as an unusual presentation of coronary allograft vasculopathy: a case report.
      Peter S, Hulme O, Deuse T, Vrtovec B, Fearon WF, Hunt S, Haddad F| | View in PubMed
    74. The potassium channel KCa3.1 as new therapeutic target for the prevention of obliterative airway disease.
      Hua X, Deuse T, Chen YJ, Wulff H, Stubbendorff M, Köhler R, Miura H, Länger F, Reichenspurner H, Robbins RC, Schrepfer S| | View in PubMed
    75. Severe bacterial superinfection based on influenza A (H1N1) pneumonia in a heart-lung transplant recipient.
      Yildirim Y, Pecha S, Sill B, Deuse T, Reichenspurner H| | View in PubMed
    76. Concomitant transcatheter aortic valve and left ventricular assist device implantation.
      Baum C, Seiffert M, Treede H, Reichenspurner H, Deuse T| | View in PubMed
    77. Late profound muscle weakness following heart transplantation due to Danon disease.
      Van Der Starre P, Deuse T, Pritts C, Brun C, Vogel H, Oyer P| | View in PubMed
    78. Significant reduction of acute cardiac allograft rejection by selective janus kinase-1/3 inhibition using R507 and R545.
      Deuse T, Hua X, Taylor V, Stubbendorff M, Baluom M, Chen Y, Park G, Velden J, Streichert T, Reichenspurner H, Robbins RC, Schrepfer S| | View in PubMed
    79. Clinical and functional correlates of early microvascular dysfunction after heart transplantation.
      Haddad F, Khazanie P, Deuse T, Weisshaar D, Zhou J, Nam CW, Vu TA, Gomari FA, Skhiri M, Simos A, Schnittger I, Vrotvec B, Hunt SA, Fearon WF| | View in PubMed
    80. Successful extracorporeal membrane oxygenation weaning after cardiac resynchronization therapy device implantation in a patient with end-stage heart failure.
      Pecha S, Yildirim Y, Reichenspurner H, Deuse T| | View in PubMed
    81. Human internal mammary artery (IMA) transplantation and stenting: a human model to study the development of in-stent restenosis.
      Hua X, Deuse T, Michelakis ED, Haromy A, Tsao PS, Maegdefessel L, Erben RG, Bergow C, Behnisch BB, Reichenspurner H, Robbins RC, Schrepfer S| | View in PubMed
    82. Cardiac paraganglioma: diagnostic and surgical challenges.
      Huo JL, Choi JC, DeLuna A, Lee D, Fleischmann D, Berry GJ, Deuse T, Haddad F| | View in PubMed
    83. Human leukocyte antigen I knockdown human embryonic stem cells induce host ignorance and achieve prolonged xenogeneic survival.
      Deuse T, Seifert M, Phillips N, Fire A, Tyan D, Kay M, Tsao PS, Hua X, Velden J, Eiermann T, Volk HD, Reichenspurner H, Robbins RC, Schrepfer S| | View in PubMed
    84. Immunobiology of naïve and genetically modified HLA-class-I-knockdown human embryonic stem cells.
      Deuse T, Seifert M, Phillips N, Fire A, Tyan D, Kay M, Tsao PS, Hua X, Velden J, Eiermann T, Volk HD, Reichenspurner H, Robbins RC, Schrepfer S| | View in PubMed
    85. Surgical technique of lower lobe lung transplantation.
      Deuse T, Sill B, von Samson P, Yildirim Y, Kugler C, Oldigs M, Klose H, Meierling S, Rabe KF, Reichenspurner H| | View in PubMed
    86. Bioluminescence imaging for assessment of immune responses following implantation of engineered heart tissue (EHT).
      Conradi L, Pahrmann C, Schmidt S, Deuse T, Hansen A, Eder A, Reichenspurner H, Robbins RC, Eschenhagen T, Schrepfer S| | View in PubMed
    87. Minimally invasive resection of a right atrial mass in a cardiac transplant recipient: a case report.
      Conradi L, Deuse T, Treede H, Seiffert M, Adam M, Koelble K, Costard-Jaeckle A, Wagner FM, Reichenspurner H| | View in PubMed
    88. Antibody response after a single dose of an AS03-adjuvanted split-virion influenza A (H1N1) vaccine in heart transplant recipients.
      Meyer S, Adam M, Schweiger B, Ilchmann C, Eulenburg C, Sattinger E, Runte H, Schlüter M, Deuse T, Reichenspurner H, Costard-Jäckle A| | View in PubMed
    89. Orthotopic aortic transplantation: a rat model to study the development of chronic vasculopathy.
      Stubbendorff M, Deuse T, Hammel A, Robbins RC, Reichenspurner H, Schrepfer S| | View in PubMed
    90. Transcatheter aortic valve implantation in a heart transplant recipient: a case report.
      Seiffert M, Meyer S, Franzen O, Conradi L, Baldus S, Schirmer J, Deuse T, Costard-Jaeckle A, Reichenspurner H, Treede H| | View in PubMed
    91. Immunogenicity and immunomodulatory properties of umbilical cord lining mesenchymal stem cells.
      Deuse T, Stubbendorff M, Tang-Quan K, Phillips N, Kay MA, Eiermann T, Phan TT, Volk HD, Reichenspurner H, Robbins RC, Schrepfer S| | View in PubMed
    92. Sustained inhibition of epsilon protein kinase C inhibits vascular restenosis after balloon injury and stenting.
      Deuse T, Koyanagi T, Erben RG, Hua X, Velden J, Ikeno F, Reichenspurner H, Robbins RC, Mochly-Rosen D, Schrepfer S| | View in PubMed
    93. Review of heart-lung transplantation at Stanford.
      Deuse T, Sista R, Weill D, Tyan D, Haddad F, Dhillon G, Robbins RC, Reitz BA| | View in PubMed
    94. Non-volume-loaded heart provides a more relevant heterotopic transplantation model.
      Tang-Quan KR, Bartos J, Deuse T, Churchill E, Schäfer H, Reichenspurner H, Mochly-Rosen D, Robbins RC, Schrepfer S| | View in PubMed
    95. Heterotopic and orthotopic tracheal transplantation in mice used as models to study the development of obliterative airway disease.
      Hua X, Deuse T, Tang-Quan KR, Robbins RC, Reichenspurner H, Schrepfer S| | View in PubMed
    96. Asymptomatic infection with novel influenza A/H1N1 virus in a heart transplant recipient.
      Meyer S, Ilchmann C, Adam M, Sattinger E, Siamkouris D, Arunagirinathan U, Deuse T, Wagner FM, Reichenspurner H, Costard-Jaeckle A| | View in PubMed
    97. Mechanisms behind local immunosuppression using inhaled tacrolimus in preclinical models of lung transplantation.
      Deuse T, Blankenberg F, Haddad M, Reichenspurner H, Phillips N, Robbins RC, Schrepfer S| | View in PubMed
    98. Changing trends in infectious disease in heart transplantation.
      Haddad F, Deuse T, Pham M, Khazanie P, Rosso F, Luikart H, Valantine H, Leon S, Vu TA, Hunt SA, Oyer P, Montoya JG| | View in PubMed
    99. LAD-ligation: a murine model of myocardial infarction.
      Kolk MV, Meyberg D, Deuse T, Tang-Quan KR, Robbins RC, Reichenspurner H, Schrepfer S| | View in PubMed
    100. Alternative technique for salvage of donor lungs with insufficient atrial cuffs.
      Yarbrough WM, Bates MJ, Deuse T, Tang DG, Robbins RC, Reitz BA, Mallidi HR| | View in PubMed
    101. Hepatocyte growth factor or vascular endothelial growth factor gene transfer maximizes mesenchymal stem cell-based myocardial salvage after acute myocardial infarction.
      Deuse T, Peter C, Fedak PW, Doyle T, Reichenspurner H, Zimmermann WH, Eschenhagen T, Stein W, Wu JC, Robbins RC, Schrepfer S| | View in PubMed
    102. Imaging in-stent restenosis: an inexpensive, reliable, and rapid preclinical model.
      Deuse T, Ikeno F, Robbins RC, Schrepfer S| | View in PubMed
    103. Heart-lung transplantation in situs inversus totalis.
      Deuse T, Reitz BA| | View in PubMed
    104. Right ventricular dysfunction predicts poor outcome following hemodynamically compromising rejection.
      Haddad F, Fisher P, Pham M, Berry G, Weisshaar D, Kuppahally S, Vrtovec B, Deuse T, Virani S, Fearon W, Valantine H, Hunt S| | View in PubMed
    105. A novel JAK3 inhibitor, R348, attenuates chronic airway allograft rejection.
      Velotta JB, Deuse T, Haddad M, Masuda E, Park G, Carroll D, Taylor V, Robbins RC, Schrepfer S| | View in PubMed
    106. Heart transplantation in situs inversus totalis.
      Deuse T, Reitz BA| | View in PubMed
    107. Twenty-year survivors of heart transplantation at Stanford University.
      Deuse T, Haddad F, Pham M, Hunt S, Valantine H, Bates MJ, Mallidi HR, Oyer PE, Robbins RC, Reitz BA| | View in PubMed
    108. Novel immunosuppression: R348, a JAK3- and Syk-inhibitor attenuates acute cardiac allograft rejection.
      Deuse T, Velotta JB, Hoyt G, Govaert JA, Taylor V, Masuda E, Herlaar E, Park G, Carroll D, Pelletier MP, Robbins RC, Schrepfer S| | View in PubMed
    109. Prevention and inhibition but not reversion of chronic allograft vasculopathy by FK778.
      Deuse T, Hoyt G, Koyanagi T, Robbins RC, Schrepfer S| | View in PubMed
    110. Introducing the first polymer-free leflunomide eluting stent.
      Deuse T, Erben RG, Ikeno F, Behnisch B, Boeger R, Connolly AJ, Reichenspurner H, Bergow C, Pelletier MP, Robbins RC, Schrepfer S| | View in PubMed
    111. Fluoroscopy to assess late heart and lung perforation by a permanent ventricular pacemaker lead. A case complicated by isolated hemothorax.
      Mortensen K, Aydin MA, Goldmann B, Deuse T, Willems S, Ventura R| | View in PubMed
    112. Effect of inhaled tacrolimus on cellular and humoral rejection to prevent posttransplant obliterative airway disease.
      Schrepfer S, Deuse T, Reichenspurner H, Hoffmann J, Haddad M, Fink J, Fischbein MP, Robbins RC, Pelletier MP| | View in PubMed
    113. Is the malononitrilamide FK778 better for the prevention of acute or chronic rejection?
      Deuse T, Schrepfer S, Pelletier MP, Fischbein MP, Robbins RC, Reichenspurner H| | View in PubMed
    114. Stem cell transplantation: the lung barrier.
      Schrepfer S, Deuse T, Reichenspurner H, Fischbein MP, Robbins RC, Pelletier MP| | View in PubMed
    115. Techniques for experimental heterotopic and orthotopic tracheal transplantations - When to use which model?
      Deuse T, Schrepfer S, Reichenspurner H, Hoyt G, Fischbein MP, Robbins RC, Pelletier MP| | View in PubMed
    116. Simplified protocol to isolate, purify, and culture expand mesenchymal stem cells.
      Schrepfer S, Deuse T, Lange C, Katzenberg R, Reichenspurner H, Robbins RC, Pelletier MP| | View in PubMed
    117. Experimental orthotopic tracheal transplantation: The Stanford technique.
      Schrepfer S, Deuse T, Hoyt G, Sheikh AY, Hoffmann J, Reichenspurner H, Robbins RC, Pelletier MP| | View in PubMed
    118. FK778 in experimental xenotransplantation: a detailed analysis of drug efficacy.
      Schrepfer S, Deuse T, Koch-Nolte F, Krieger T, Haddad M, Schäfer H, Pelletier MP, Robbins RC, Reichenspurner H| | View in PubMed
    119. Inhibition of restenosis development after mechanical injury: a new field of application for malononitrilamides?
      Schrepfer S, Deuse T, Sultan KR, Haddad M, Böger R, Münzel T, Schäfer H, Pelletier MP, Robbins RC, Reichenspurner H| | View in PubMed
    120. The selective estrogen receptor-beta agonist biochanin A shows vasculoprotective effects without uterotrophic activity.
      Schrepfer S, Deuse T, Münzel T, Schäfer H, Braendle W, Reichenspurner H| | View in PubMed
    121. Heparins increase endothelial nitric oxide bioavailability by liberating vessel-immobilized myeloperoxidase.
      Baldus S, Rudolph V, Roiss M, Ito WD, Rudolph TK, Eiserich JP, Sydow K, Lau D, Szöcs K, Klinke A, Kubala L, Berglund L, Schrepfer S, Deuse T, Haddad M, Risius T, Klemm H, Reichenspurner HC, Meinertz T, Heitzer T| | View in PubMed
    122. FK778: new cellular and molecular mechanisms of action.
      Schrepfer S, Deuse T, Koch-Nolte F, Detter C, Reichenspurner H| | View in PubMed
    123. Sirolimus and FK778: a comparison of two anti-proliferative immunosuppressants for prevention of experimental obliterative airway disease.
      Deuse T, Schrepfer S, Koch-Nolte F, Haddad M, Schäfer H, Detter C, Reichenspurner H| | View in PubMed
    124. Tracheal allograft transplantation in rats: the role of different immunosuppressants on preservation of respiratory epithelium.
      Schrepfer S, Deuse T, Sydow K, Schäfer H, Detter C, Reichenspurner H| | View in PubMed
    125. The phytoestrogen biochaninA weakens acute cardiac allograft rejection without affecting the reproductive system.
      Schrepfer S, Deuse T, Schäfer H, Koch-Nolte F, Braendle W, Reichenspurner H| | View in PubMed
    126. FK778 and tacrolimus prevent the development of obliterative airway disease after heterotopic rat tracheal transplantation.
      Deuse T, Schrepfer S, Koch-Nolte F, Haddad M, Schwedhelm E, Böger R, Schäfer H, Detter C, Reichenspurner H| | View in PubMed
    127. FK778, a novel immunosuppressive agent, reduces early adhesion molecule up-regulation and prolongs cardiac allograft survival.
      Schrepfer S, Deuse T, Schäfer H, Reichenspurner H| | View in PubMed
    128. Video and robotic-assisted minimally invasive mitral valve surgery: a comparison of the Port-Access and transthoracic clamp techniques.
      Reichenspurner H, Detter C, Deuse T, Boehm DH, Treede H, Reichart B| | View in PubMed
    129. FK778 attenuates lymphocyte-endothelium interaction after cardiac transplantation: in vivo and in vitro studies.
      Deuse T, Schrepfer S, Schäfer H, Koch-Nolte F, Schwedhelm E, Böger RH, Reichenspurner H| | View in PubMed
    130. The interaction between FK778 and tacrolimus in the prevention of rat cardiac allograft rejection is dose dependent.
      Deuse T, Schrepfer S, Reichenspurner H| | View in PubMed
    131. Immunosuppression with FK778 and mycophenolate mofetil in a rat cardiac transplantation model.
      Deuse T, Schrepfer S, Reichenspurner H| | View in PubMed
    132. Successful resection of a symptomatic right ventricular lipoma.
      Schrepfer S, Deuse T, Detter C, Treede H, Koops A, Boehm DH, Willems S, Lacour-Gayet F, Reichenspurner H| | View in PubMed
    133. Robotically assisted coronary artery bypass surgery with the ZEUS telemanipulator system.
      Boehm DH, Detter C, Arnold MB, Deuse T, Reichenspurner H| | View in PubMed
    134. Correlation between mononuclear infiltration and changes in VASP phosphorylation patterns after heterotopic cardiac transplantation in the rat.
      Deuse T, Lange V, Schrepfer S, Eigenthaler M, Reichart B, Walter U, Elert O| | View in PubMed
    135. Early and midterm results after coronary artery bypass grafting with and without cardiopulmonary bypass: which patient population benefits the most?
      Deuse T, Detter C, Samuel V, Boehm DH, Reichenspurner H, Reichart B| | View in PubMed
    136. New technique for chest opening in mice: U-sternotomy.
      Schrepfer S, Deuse T, Reichenspurner H| | View in PubMed
    137. Comparison of two stabilizer concepts for off-pump coronary artery bypass grafting.
      Detter C, Deuse T, Christ F, Boehm DH, Reichenspurner H, Reichart B| | View in PubMed
    138. Robotically-assisted coronary artery surgery with and without cardiopulmonary bypass - from first clinical use to endoscopic operation.
      Detter C, Boehm DH, Reichenspurner H, Deuse T, Arnold M, Reichart B| | View in PubMed
    139. Effect of hemodynamics on graft rejection in the heterotopic heart transplantation model.
      Lange V, Gassel AM, Deuse T, Ulrichs K, Silber RE| | View in PubMed