Biography
Education
B.Sc. (Biology and Chemistry) Tribhuvan University, Kathmandu, Nepal
M.Sc. (Chemistry) Tribhuvan University, Kathmandu, Nepal, Advisor: Prof. Vishwanath Pd. Agrawal, PhD
Ph.D. (Biochemistry), Miami University, Oxford, OH, Advisor: Prof. Michael Crowder, PhD
N/A
Awards & Honors
Award | Conferred By | Date |
---|---|---|
Pediatric Research Fund – CHRP Award | Stanford University, Stanford, CA | 2009/2010 |
Pediatric Research Fund – CHRP Award | Stanford University, Stanford, CA | 2008/2009 |
Deans Postdoctoral Fellowship | Stanford University, Stanford, CA | 2007/2008 |
Doctoral-Undergraduate Opportunities in Scholarship (DUOS) award for two consecutive years (2003 and | Miami University, Oxford, OH | 2003/2005 |
William Hale Charch Graduate Fellowship | Miami University, Oxford, OH | 2002/2003 |
In the News
Research Narrative
Dr. Sigdel's research is driven by two major factors. First, there is an unprecedented pressure to deliver new and improved diagnostic and treatment options to patients. Second, due to improved understanding of biological intricacies with ever improving molecular assays have placed us in a much better position to look for disease specific biomarkers that once validated can be used in the clinics in order to provide timely and accurate assessment of health status of patients.
Research Interests
Biomarker DIscovery
Proteomics
Immunology
Organ Transplantation
Liver Cancer
Kidney Transplantation
High Throughput Data
Bioinformatics
Research Pathways
Publications
- Nepal Family Cohort study: a study protocol.| | PubMed
- Gene expression-based molecular scoring of pancreas transplant rejection for a quantitative assessment of rejection severity and resistance to treatment.| | PubMed
- Proteome Analysis for Inflammation Related to Acute and Convalescent Infection.| | PubMed
- Transcriptional and spatial profiling of the kidney allograft unravels a central role for FcyRIII+ innate immune cells in rejection.| | PubMed
- Plasma proteome perturbation for CMV DNAemia in kidney transplantation.| | PubMed
- Perturbations in podocyte transcriptome and biological pathways induced by FSGS associated circulating factors.| | PubMed
- Longitudinal serum proteomics analyses identify unique and overlapping host response pathways in Lyme disease and West Nile virus infection.| | PubMed
- Perturbations of the T-cell immune repertoire in kidney transplant rejection.| | PubMed
- A reference tissue atlas for the human kidney.| | PubMed
- Mass cytometry reveals single-cell kinetics of cytotoxic lymphocyte evolution in CMV-infected renal transplant patients.| | PubMed