Biography
Mackersie is a certified by the American Board of General Surgery, general certificate with subspecialty in surgical critical care. His practice is in general and trauma surgery, which includes vascular and thoracic surgery. In addition, he is a regular attending on the Surgical Critical Care Service at Zuckerberg San Francisco General Hospital and Trauma Center and serves as Vice-Chief of Surgery there.
Dr. Mackersie is a graduate of UC Berkeley and Michigan State University Medical School. He completed his internship, residency and chief residency training in general surgery and surgical critical care at the University of California, San Francisco, where he continued his specialty training and completed a trauma research fellowship. Dr. Mackersie joined the faculty at the University of California, San Diego University Hospital from 1985-1991.
Dr. Mackersie was appointed the Trauma Medical Director in 1992 at the University of California/San Francisco General Hospital (now Zuckerberg San Francisco General) and has been instrumental in expanding the multidisciplinary activities related to the Trauma Program. Dr. Mackersie currently serves as an officer for several surgical organizations and is a Governor of the American College of Surgeons. Dr. Mackersie has been appointed Secretary/Treasurer for the American Association for the Surgery of Trauma. Dr. Mackersie has also expanded the Trauma Nurse Practitioner program, and has progressed in developing the first aero-medical transport facility at San Francisco General Hospital. He has also been appointed Commissioner for the State of California Emergency Medical Services Authority, which is appointed by the Governor/California Speaker of the House.
Dr. Mackersie continues to direct the national program in Trauma System Planning and Evaluation for the American College of Surgeons, which includes the development of national benchmarks for trauma systems and trauma centers, and the creation of national guidelines for trauma systems development.
Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
University of California, San Francisco | Residency | School of Medicine |
Board Certifications
- American Board of Surgery, 1986
- American Board of Surgery, Surgical Critical Care, 1988
Clinical Expertise
General Surgery
Surgical Critical Care
Trauma Surgery
Vascular Surgery
In the News
Research Narrative
- Inflammatory Lung Injury following major injury: One of the main areas of focus has been post-traumatic inflammatory lung injury. This collaborative research effort has continued, with new reports of the clinical syndrome of ARDS (ref # 63), the impact of ARDS on specific outcomes (ref # 62), and a recent report examining surrogate serum markers predictive of inflammatory lung injury. (ref # 65). The most recent work, still in preparation (Abstract, WIP ref # 3), attemps to link elements of inflammation with post-traumatic coagulopathy, and to better define the nature of early coagulopathy (pre-massive transfusion) that follows shock, traumatic brain injury, and major organ injury.
- Ventilatory management of patients with ARDS (refs # 66,67). Technical clinical studies performed in ICU patients with ARDS that attempt to expand our understanding of "optimal" modes of lung protective ventilation (LPV) in the setting or acute lung injury. LPV strategies are one of the few, if not the only demonstrable intervention having an impact on the outcome from ARDS over the past 15 years.
- Violence prevention recidivism (Abstracts/WIP ref # 1). Work in progress, this is part of an ongoing clinical and programmatic study that screens victims of youth violence & assesses the likelihood of recidivism. "High risk" patients are then referred into a program linking hospital services with post-discharge neighborhood/community services for violence prevention. A randomized study is being designed to compare recidivism outcomes with and without programmatic influence.
Research Interests
- Trauma systems development
- Inflammatory lung injury following major injury
- Ventilatory management of patients with ARDS
- Violence Prevention
Publications
- Field triage, and the fragile supply of "optimal resources" for the care of the injured patient.| | PubMed
- History of trauma field triage development and the American College of Surgeons criteria.| | PubMed
- Effects of tidal volume on work of breathing during lung-protective ventilation in patients with acute lung injury and acute respiratory distress syndrome.| | PubMed
- Work of breathing during lung-protective ventilation in patients with acute lung injury and acute respiratory distress syndrome: a comparison between volume and pressure-regulated breathing modes.| | PubMed
- Serum levels of Hsp60 correlate with the development of acute lung injury after trauma.| | PubMed
- Acute respiratory distress syndrome criteria in trauma patients: why the definitions do not work.| | PubMed
- An epidemic of methicillin-resistant Staphylococcus aureus soft tissue infections among medically underserved patients.| | PubMed
- The development of acute lung injury is associated with worse neurologic outcome in patients with severe traumatic brain injury.| | PubMed
- The effects of tidal volume demand on work of breathing during simulated lung-protective ventilation.| | PubMed
- Serum levels of Hsp 72 measured early after trauma correlate with survival.| | PubMed