Biography
Schneider's participation in vascular disease research over the past 25 years has included designing trials to evaluate new treatments, providing oversight, analyzing data, presenting findings and publishing results. He has served as principal investigator for numerous national clinical trials. He has consulted on trials to show efficacy and gain regulatory approval for many vascular devices, met with the Food and Drug Administration (FDA) and testified at FDA panel hearings. His experience also includes performing procedures for several first-in-human trials.
Schneider earned his medical degree from the Johns Hopkins School of Medicine and completed a residency in general surgery and a fellowship in vascular surgery at UCSF. Before joining the UCSF faculty, he was the founding member and chief of Kaiser Permanente Hawaii's vascular surgery division. At Kaiser, he developed an aneurysm screening and monitoring program and a registry for patients with carotid artery disease. He oversaw development of the Kaiser system's first operating room for endovascular surgery (less invasive procedures to repair blood vessels).
Schneider has served as president of the Western Vascular Society and on many committees of the Society for Vascular Surgery. He is a fellow of the American College of Surgeons, distinguished fellow of the Society for Vascular Surgery and fellow of the International Society of Vascular Surgery. He has authored several textbooks, including the fourth edition of Endovascular Skills: Guidewire and Catheter Skills for Endovascular Surgery, as well as more than 100 articles in peer-reviewed journals. He founded two medical device companies, has served as an adviser to many others and holds numerous patents.
Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
UCSF | Fellowship | Vascular Surgery | 1991 |
UCSF | Residency | General Surgery | 1989 |
Johns Hopkins University School of Medicine | MD | 1983 |
Board Certifications
American Board of Surgery, Vascular Surgery
Clinical Expertise
Abdominal Aortic Aneurysm
Carotid Artery Disease
Complex Limb Revascularization
Critical Limb Ischemia
Diabetic Vascular Disease
Dialysis Access
Endovascular Aneurysm Repair
Mesenteric Artery Disease
Peripheral Artery Disease
Thoracic Aortic Aneurysm
Thoracic Outlet Syndrome
Research Narrative
Dr. Schneider has served as National Principal Investigator for numerous clinical trials. Over 25 years, he has been a strong proponent of clinical research in vascular disease and has participated extensively in trial design, oversight, core lab analysis, events committees, data analysis, follow up, presentation, and publication. He has consulted on the regulatory pathway and pivotal trials for many vascular devices, has participated in numerous meetings with the FDA and has testified at FDA panel hearings. His experience includes performing procedures for several first-in-human trials.
Publications
- The Impact of Revascularization Strategy on Clinical Failure, Hemodynamic Failure and Chronic Limb Threatening Ischemia Symptoms in the BEST-CLI Trial.| | PubMed
- Paclitaxel-Mortality Risk Hypothesis Debunked: What We Learned and How It Will Change Future Clinical Trials.| | PubMed
- The "Woundosome" Concept and Its Impact on Procedural Outcomes in Patients With Chronic Limb-Threatening Ischemia.| | PubMed
- Why selective screening for asymptomatic carotid stenosis is currently appropriate: a special report.| | PubMed
- Relevance of BEST-CLI trial endpoints in a tertiary care limb preservation program.| | PubMed
- The End of a Controversy: The Rise, Fall, and Redemption of Paclitaxel-Coated Devices.| | PubMed
- Serration Angioplasty Is Associated With Less Recoil in Infrapopliteal Arteries Compared With Plain Balloon Angioplasty.| | PubMed
- Recent advances and controversial issues in the optimal management of asymptomatic carotid stenosis.| | PubMed
- Outcomes following carotid revascularization for stroke stratified by Modified Rankin Scale and time of intervention.| | PubMed
- Mortality in randomised controlled trials using paclitaxel-coated devices for femoropopliteal interventional procedures: an updated patient-level meta-analysis.| | PubMed
- The conundrum of below the knee (BTK) drug delivery.| | PubMed
- Female and male patients have similar outcomes after transcarotid artery revascularization in prospective trials.| | PubMed
- Treatment effect of medial arterial calcification in below-knee after Auryon laser atherectomy using micro-CT and histologic evaluation.| | PubMed
- Delphi Consensus on Reporting Standards in Clinical Studies for Endovascular Treatment of Acute Iliofemoral Venous Thrombosis and Chronic Iliofemoral Venous Obstruction.| | PubMed
- How I do it: optimizing angioplasty using the Tack endovascular system in the management of chronic limb threatening ischemia.| | PubMed
- Best Medical Treatment Alone Is Adequate for the Management of All Patients With Asymptomatic Carotid Stenosis, or "Alice in Wonderland".| | PubMed
- High-Risk Characteristics for Clinical Failure after Isolated Femoropopliteal Peripheral Vascular Interventions.| | PubMed
- Long-term outcomes of peripheral atherectomy for femoropopliteal endovascular interventions.| | PubMed
- Cognitive Impairment is Common in a Veterans Affairs Population with Peripheral Arterial Disease.| | PubMed
- Presenting limb severity is associated with long-term outcomes after infrainguinal revascularization for chronic limb-threatening ischemia.| | PubMed
- Efficacy and safety of single versus dual antiplatelet therapy in carotid artery stenting.| | PubMed
- Physiologic risk factors increase risk of myocardial infarction with transcarotid artery revascularization in prospective trials.| | PubMed
- In-hospital outcomes after carotid endarterectomy for stroke stratified by modified Rankin scale score and time of intervention.| | PubMed
- Surgery or Endovascular Therapy for Chronic Limb-Threatening Ischemia.| | PubMed
- Comparison of Drug-Coated Balloons vs Bare-Metal Stents in Patients With Femoropopliteal Arterial Disease.| | PubMed
- Determinants of Drug-Coated Balloon Failure in Patients Undergoing Femoropopliteal Arterial Intervention.| | PubMed
- Editor's Choice - European Society for Vascular Surgery (ESVS) 2023 Clinical Practice Guidelines on Radiation Safety.| | PubMed
- State-of-the-Art Endovascular Therapies for the Femoropopliteal Segment: Are We There Yet?| | PubMed
- Pedal arterial calcification score is associated with hemodynamic change and major amputation after infrainguinal revascularization for chronic limb-threatening ischemia.| | PubMed
- Limb-based patency as a measure of effective revascularization for chronic limb-threatening ischemia.| | PubMed
- Concomitant Drug-Coated Balloon Angioplasty With Bail-Out Use of Eluvia Drug-Eluting Stent: Is There Any Downside to a Double Dose of Paclitaxel?| | PubMed
- One-year outcomes after transcarotid artery revascularization (TCAR) in the ROADSTER 2 trial.| | PubMed
- Applicability of the Vascular Quality Initiative mortality prediction model for infrainguinal revascularization in a tertiary limb preservation center population.| | PubMed
- Balloon dilation strategy does not affect outcomes for transcarotid artery revascularization in prospective trials.| | PubMed
- Carotid Interventions for Women: The Hazards and Benefits.| | PubMed
- It is time for a deep dive on our business model.| | PubMed
- Objective Outcome Measures for Trials in Patients With Chronic Limb-Threatening Ischemia Across 2 Decades: Analysis and Recommendations.| | PubMed
- Delphi Consensus Study Toward a Comprehensive Classification System for Angioplasty-Induced Femoropopliteal Dissection: The DISFORM Study.| | PubMed
- Endovascular treatment of high-risk peripheral vascular occlusive lesions: a review of current evidence and emerging applications of intravascular lithotripsy, atherectomy, and paclitaxel-coated devices.| | PubMed
- Efficacy and safety of perioperative dual antiplatelet therapy with ticagrelor versus clopidogrel in carotid artery stenting.| | PubMed
- Progress on developing an effective below-the-knee drug-coated balloon.| | PubMed
- Pedal arterial calcification score is associated with the risk of major amputation in chronic limb-threatening ischemia.| | PubMed
- Assessing the suitability of the carotid bifurcation for stenting: Anatomic and morphologic considerations.| | PubMed
- Policies to Encourage the Use of Biosimilars in European Countries and Their Potential Impact on Pharmaceutical Expenditure.| | PubMed
- Advances in Revascularization for Peripheral Artery Disease: Revascularization in PAD.| | PubMed
- Mortality Rates After Paclitaxel-Coated Device Use in Patients With Occlusive Femoropopliteal Disease: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials.| | PubMed
- Association of Postangioplasty Femoropopliteal Dissections With Outcomes After Drug-Coated Balloon Angioplasty in the Femoropopliteal Arteries.| | PubMed
- PROMISE I: Early feasibility study of the LimFlow System for percutaneous deep vein arterialization in no-option chronic limb-threatening ischemia: 12-month results.| | PubMed
- Understanding value and patient complexity among common inpatient vascular surgery procedures.| | PubMed
- Closure device use for common femoral artery antegrade access is higher risk than retrograde access.| | PubMed
- The Global Limb Anatomic Staging System is associated with outcomes of infrainguinal revascularization in chronic limb threatening ischemia.| | PubMed
- Venous outcomes at 1 year after using the femoral vein as a conduit for passage of percutaneous femoropopliteal bypass.| | PubMed
- Duplex Ultrasound Surveillance after Transcarotid Artery Revascularization (TCAR) in Clinical Practice.| | PubMed
- Impact of changes in the methodology of external price referencing on medicine prices: discrete-event simulation.| | PubMed
- A Review and Proposed Classification System for the No-Option Patient With Chronic Limb-Threatening Ischemia.| | PubMed
- Effects of external crushing forces on a novel below-the-knee vascular implant.| | PubMed
- Update on paclitaxel for femoral-popliteal occlusive disease in the 15 months following a summary level meta-analysis demonstrated increased risk of late mortality and dose response to paclitaxel.| | PubMed
- Paclitaxel exposure: Long-term safety and effectiveness of a drug-coated balloon for claudication in pooled randomized trials.| | PubMed
- Early Outcomes in the ROADSTER 2 Study of Transcarotid Artery Revascularization in Patients With Significant Carotid Artery Disease.| | PubMed
- Corrigendum to "Global Vascular Guidelines on the Management of Chronic Limb-Threatening Ischaemia" [Eur J Vasc Endovasc Surg 58 (1S) (2019) 1-109>].| | PubMed
- Total IN.PACT All-Subjects One-Year Analysis and Standard vs Broader Implications.| | PubMed
- Balloon Angioplasty of Infrapopliteal Arteries: A Systematic Review and Proposed Algorithm for Optimal Endovascular Therapy.| | PubMed
- Endovascular Intervention for the Treatment of Trans-Atlantic Inter-Society Consensus (TASC) D Femoropopliteal Lesions: A Systematic Review and Meta-Analysis.| | PubMed
- Safety and Efficacy of Drug-Coated Balloon Angioplasty for the Treatment of Chronic Limb-Threatening Ischemia: A Systematic Review and Meta-Analysis.| | PubMed
- New Innovations and Devices in the Management of Chronic Limb-Threatening Ischemia.| | PubMed
- Mortality and Paclitaxel-Coated Devices: An Individual Patient Data Meta-Analysis.| | PubMed
- Re: Risk of Death and Amputation with Use of Paclitaxel-Coated Balloons in the Infrapopliteal Arteries for Treatment of Critical Limb Ischemia: A Systematic Review and Meta-analysis of Randomized Controlled Trials.| | PubMed
- Mortality After Paclitaxel-Coated Device Use in Patients With Chronic Limb-Threatening Ischemia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.| | PubMed
- Corrigendum to 'Global Vascular Guidelines on the Management of Chronic Limb-Threatening Ischemia' [European Journal of Vascular & Endovascular Surgery 58/1S (2019) 1-109].| | PubMed
- Evaluation of a novel mesh-covered stent for treatment of carotid stenosis in patients at high risk for endarterectomy: 1-year results of the SCAFFOLD trial.| | PubMed
- Total IN.PACT drug-coated balloon initiative reporting pooled imaging and propensity-matched cohorts.| | PubMed
- Evolution of Average European Medicine Prices: Implications for the Methodology of External Price Referencing.| | PubMed
- Dissections After Infrainguinal Percutaneous Transluminal Angioplasty: A Systematic Review and Current State of Clinical Evidence.| | PubMed
- Long-Term Clinical Effectiveness of a Drug-Coated Balloon for the Treatment of Femoropopliteal Lesions.| | PubMed
- Affordable and equitable access to subsidised outpatient medicines? Analysis of co-payments under the Additional Drug Package in Kyrgyzstan.| | PubMed
- Disparities in Contemporary Treatment Rates of Abdominal Aortic Aneurysms Across Western Countries.| | PubMed
- Paclitaxel and Mortality: The Dose Argument Is Critical.| | PubMed
- Global Vascular Guidelines on the Management of Chronic Limb-Threatening Ischemia.| | PubMed
- Interim Results of the PROMISE I Trial to Investigate the LimFlow System of Percutaneous Deep Vein Arterialization for the Treatment of Critical Limb Ischemia.| | PubMed
- Continuous monitoring of interstitial tissue oxygen using subcutaneous oxygen microsensors: In vivo characterization in healthy volunteers.| | PubMed
- Mortality Not Correlated With Paclitaxel Exposure: An Independent Patient-Level Meta-Analysis of a Drug-Coated Balloon.| | PubMed
- A First-in-Human Evaluation of a Novel Mesh-Covered Stent for Treatment of Carotid Stenosis in Patients at High Risk for Endarterectomy: 30-Day Results of the SCAFFOLD Trial.| | PubMed
- Centers for Medicare & Medicaid Services' decision on drug-coated balloons: No additional reimbursement despite higher cost and highest levels of scientific evidence.| | PubMed
- Response by Schneider et al to Letter Regarding Article, "Treatment Effect of Drug-Coated Balloons Is Durable to 3 Years in the Femoropopliteal Arteries: Long-Term Results of the IN.PACT SFA Randomized Trial".| | PubMed
- Treatment of infrapopliteal post-PTA dissection with tack implants: 12-month results from the TOBA-BTK study.| | PubMed
- Public Health Impact of the Centers for Medicare and Medicaid Services Decision on Pass-Through Add-On Payments for Drug-Coated Balloons: A Call to Action.| | PubMed
- Treatment Effect of Drug-Coated Balloons Is Durable to 3 Years in the Femoropopliteal Arteries: Long-Term Results of the IN.PACT SFA Randomized Trial.| | PubMed
- Novel Nitinol Stent for Lesions up to 24 cm in the Superficial Femoral and Proximal Popliteal Arteries: 24-Month Results From the TIGRIS Randomized Trial.| | PubMed
- Evolution and current use of technology for superficial femoral and popliteal artery interventions for claudication.| | PubMed
- Carotid artery stenting should remain an alternative to endarterectomy in selected patients.| | PubMed
- How Can Pricing and Reimbursement Policies Improve Affordable Access to Medicines? Lessons Learned from European Countries.| | PubMed
- Will mesh-covered stents help reduce stroke associated with carotid stent angioplasty?| | PubMed
- Prevalence and function of Heschl's gyrus morphotypes in musicians.| | PubMed
- Patient-level meta-analysis of 999 claudicants undergoing primary femoropopliteal nitinol stent implantation.| | PubMed
- Western Vascular Society guidelines for transfer of patients with ruptured abdominal aortic aneurysm.| | PubMed
- Cost-Effectiveness of Endovascular Femoropopliteal Intervention Using Drug-Coated Balloons Versus Standard Percutaneous Transluminal Angioplasty: Results From the IN.PACT SFA II Trial.| | PubMed
- Prescription of Guideline-Based Medical Therapies at Discharge After Carotid Artery Stenting and Endarterectomy: An NCDR Analysis.| | PubMed
- Neural Biomarkers for Dyslexia, ADHD, and ADD in the Auditory Cortex of Children.| | PubMed
- Comparative Effectiveness of Carotid Artery Stenting Versus Carotid Endarterectomy Among Medicare Beneficiaries.| | PubMed
- Bare metal stenting of the iliac arteries.| | PubMed
- Durability of Treatment Effect Using a Drug-Coated Balloon for Femoropopliteal Lesions: 24-Month Results of IN.PACT SFA.| | PubMed
- Relationship Between Physician and Hospital Procedure Volume and Mortality After Carotid Artery Stenting Among Medicare Beneficiaries.| | PubMed
- Letter to the Editor Regarding the Article "Thyrotropin Suppression Increases the Risk of Osteoporosis Without Decreasing Recurrence in ATA Low- and Intermediate-Risk Patients with Differentiated Thyroid Carcinoma".| | PubMed
- Drug-coated balloon treatment for lower extremity vascular disease intervention: an international positioning document.| | PubMed
- The future of vascular surgery.| | PubMed
- Variability in transfer criteria for patients with ruptured abdominal aortic aneurysm in the western United States.| | PubMed
- Early experimental and clinical experience with a focal implant for lower extremity post-angioplasty dissection.| | PubMed
- Drug-coated balloon versus standard percutaneous transluminal angioplasty for the treatment of superficial femoral and popliteal peripheral artery disease: 12-month results from the IN.PACT SFA randomized trial.| | PubMed
- Stroke and the law: principles and practice.| | PubMed
- Three-phase bone scintigraphy for imaging osteoradionecrosis of the jaw.| | PubMed
- An evidence-based review of the impact of periprocedural myocardial infarction in carotid revascularization.| | PubMed
- Re-entry into the true lumen from the subintimal space.| | PubMed
- Major adverse limb events and wound healing following infrapopliteal artery stent implantation in patients with critical limb ischemia: the XCELL trial.| | PubMed
- Endovascular therapy: is it effective in the diabetic limb?| | PubMed
- Should Medicare reimbursement for carotid artery stenting be extended to standard and low risk symptomatic and asymptomatic patients with carotid stenosis?| | PubMed
- Reporting standards for carotid interventions from the Society for Vascular Surgery.| | PubMed
- Management of simultaneous common and internal carotid artery occlusive disease in the endovascular era.| | PubMed
- Asymptomatic carotid artery stenosis--medical therapy alone versus medical therapy plus carotid endarterectomy or stenting.| | PubMed
- Infrainguinal vein graft stenosis: cutting balloon angioplasty as the first-line treatment of choice.| | PubMed
- Difficult anatomy: what characteristics are critical to good outcomes of either CEA or CAS?| | PubMed
- Transient sirolimus serum levels after implantation of a sirolimus eluting stent in an infant.| | PubMed
- Early post-convulsive prolongation of QT time in children.| | PubMed
- Carotid stenting.| | PubMed
- Establishing sheath access for carotid interventions: tips and pitfalls.| | PubMed
- Optimal training strategies for carotid stenting.| | PubMed
- What are the key factors in setting up a successful carotid stent program?| | PubMed
- What are the skills that prepare vascular surgeons for carotid stenting?| | PubMed
- The route of administration (oral vs intravenous) does not influence dose or outcome in Graves' disease and unifocal autonomy.| | PubMed
- Safety and efficacy of carotid arteriography in vascular surgery practice.| | PubMed
- Advances in stent technology and drug-eluting stents.| | PubMed
- Effect of ethnicity on access and device complications during endovascular aneurysm repair.| | PubMed
- Early outcome of "cutting" balloon angioplasty for infrainguinal vein graft stenosis.| | PubMed
- Hiring practices ... not so fast!| | PubMed
- Autologous stem cell transplantation for systemic lupus erythematosus.| | PubMed
- Filter devices for cerebral protection during carotid angioplasty and stenting.| | PubMed
- Iliac angioplasty and stenting in association with infrainguinal bypasses: timing and techniques.| | PubMed
- Reliable engraftment, low toxicity, and durable remissions following allogeneic blood stem cell transplantation with minimal conditioning.| | PubMed
- Endovascular or open surgery for aortoiliac occlusive disease?| | PubMed
- Soluble endothelial adhesion molecules during paediatric cardiovascular surgery with or without cardiopulmonary bypass.| | PubMed