University of California San Francisco

Kimberly Kirkwood
Kimberly Kirkwood, MD

Professor of Surgery
Division of Surgical Oncology

Address

600 16th St, #S512F
San Francisco, CA 94158
United States

Email: [email protected]
Phone: 415-502-5577

Biography

Dr. Kimberly Kirkwood specializes in the treatment of pancreatic cancer as well as tumors of the stomach, spleen, gallbladder, bile duct and gastrointestinal tract. A skillful laparoscopic surgeon, she is an expert in applying minimally invasive techniques to treat abdominal tumors and has a particular interest in improving outcomes for patients after pancreas surgery.  Dr. Kirkwood is a member of the UCSF Helen Diller Family Comprehensive Cancer Center and Participates in Cancer Center Clinical Trials.

Dr. Kirkwood earned a medical degree at the University of Pennsylvania and completed a surgical residency and a fellowship in advanced general surgery with a focus on pancreatic surgery at Massachusetts General Hospital. She also completed a three-year surgical research fellowship at UCLA in hepatobiliary disease. Dr. Kirkwood is active in many national societies including the Pancreas Club, Society for Surgery of the Alimentary Tract, Association for Academic Surgeons and she is on the Executive Council of the Society of University Surgeons. Her NIH-funded research focuses on pancreatic inflammatory pain and on the many factors which may improve outcomes for patients following resection of pancreatic tumors. 

Videos

Awards & Honors

Award Conferred By Date
Excellence in Teaching Award Inaugural, UCSF Department of Surgery Junior Residents 2015
Excellence in Teaching Award UCSF Department of Surgery Chief Residents 2014
Excellence in Teaching Award UCSF School of Medicine, Surgical Clerkship 2013
Excellence in Teaching Award UCSF Department of Surgery Chief Residents 2012
AGA Student Abstract Prize (Victoria Lyo), American Gastroenterological Association (AGA) Foundation 2010
Howard Hughes Research Fellowship (Victoria Lyo), Howard Hughes Medical Institute 2010
Howard Hughes Research Fellowship (Victoria Lyo), Howard Hughes Medical Institute 2010
Pancreas Club Warren Award (Victoria Lyo), Pancreas Club 2010
Kaiser Award for Excellence in Teaching Nomination UCSF School of Medicine 2010
Excellence in Teaching Award UCSF Department of Surgery Chief Residents 2008/2009
Excellence in Teaching Award UCSF Department of Surgery Chief Residents 2008/2009
Excellence in Teaching Award UCSF Department of Surgery Chief Residents 2004
Kaiser Award for Excellence in Teaching Nomination UCSF School of Medicine 2004
Excellence in Teaching Award UCSF Department of Surgery Residents 2001
Kaiser Award for Excellence in Teaching Nomination UCSF School of Medicine 1999
Kaiser Award for Excellence in Teaching Nomination UCSF School of Medicine 1997
Claude E. Welch Research Fellowship Award Department of Surgery, Massachusetts General Hospita 1989/1990
President, Alpha Omega Alpha National Medical Honor Society University of Pennsylvania Chapter 1983
Phi Beta Kappa National Honor Society Phi Beta Kappa National Honor Society 1981
Walter Croll Scholarship University of Pennsylvania School of Medicine 1981

Education

Institution Degree Dept or School End Date
UCSF General Surgery Board Certification Department of Surgery 2014
UCSF General Surgery Board Certification Department of Surgery 2004
Massachusetts General Hospital Clinical Instructor/Pancreas Fellow Department of Surgery 1994
Massachusetts General Hospital Pancreas/Advanced General Surgery Fellowship Department of Surgery 1994
Massachusetts General Hospital Residency in General Surgery Department of Surgery 1993
UCLA Pancreas/GI Research Fellowship Department of Surgery 1991
University of Pennsylvania M.D. School of Medicine 1985
Reed College B.A. 1981

Board Certifications

  • American Board of Surgery, 1994, recertified 2014

Clinical Expertise

Benign Pancreatic Lesions
Biliary Tract Surgery
Gallbladder Surgery
Pancreatic Cancer
Stomach and Gastrointestinal Surgery

Clinical Trials

  1. Comparing Two Methods to Follow Patients With Pancreatic Cysts (NCT04239573)
    Related Conditions: Pancreatic Cancer, Pancreatic Cyst, Pancreatic Neoplasms| Start Date: | End Date:
  2. UCSF PANC Cyst Registry (NCT04291651)
    Related Conditions: Pancreatic Cyst, Pancreatic Cancer, Pancreatic Neoplasms, Pancreatic Diseases, Intraductal Papillary Mucinous Neoplasm, Pancreatic Ductal Adenocarcinoma, Neoplasms| Start Date: | End Date:

Grants and Funding

  • Molecular Correlates of progression in pancreatic cystic neoplasms | NCI/NIH | 2015-07-01 - 2021-06-30 | Role: Site Principal Investigator, UCSF
  • Minimally Invasive Classification of Pancreatic Cystic Neoplasms | V Foundation | 2017-11-01 - 2020-11-01 | Role: Principal Investigator
  • Development of fluorogenic substrates for the diagnosis of pancreatic cysts | UCSF Clinical and Translational Sciences Institute | 2017-02-01 - 2018-06-30 | Role: Principal Investigator
  • Non-invasive Differentiation of Benign Lesions from Aggressive Pancreatic Cancer | NIH | 2015-01-01 - 2017-12-31 | Role: Co-Principal Investigator
  • Neural Regulation of Pancreatic Function | NIH | 1994-05-15 - 2014-03-31 | Role: Principal Investigator

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 61
  1. A Novel Machine Learning Approach to Predict Textbook Outcome in Colectomy.
    Ashraf Ganjouei A, Romero-Hernandez F, Conroy PC, Miller PN, Calthorpe L, Wang JJ, Lin JJ, Feng J, Kirkwood KS, Alseidi A, Sarin A, Adam MA| | View in PubMed
  2. A Machine Learning Approach to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy Using Only Preoperatively Known Data.
    Ashraf Ganjouei A, Romero-Hernandez F, Wang JJ, Casey M, Frye W, Hoffman D, Hirose K, Nakakura E, Corvera C, Maker AV, Kirkwood KS, Alseidi A, Adam MA| | View in PubMed
  3. ASO Visual Abstract: National Practice Patterns in Malignant Peritoneal Mesothelioma-Updates in Management and Survival.
    Calthorpe L, Romero-Hernandez F, Casey M, Nunez M, Conroy PC, Hirose K, Kim A, Kirkwood K, Maker AV, Corvera C, Nakakura E, Alseidi A, Adam MA| | View in PubMed
  4. National Practice Patterns in Malignant Peritoneal Mesothelioma: Updates in Management and Survival.
    Calthorpe L, Romero-Hernandez F, Casey M, Nunez M, Conroy PC, Hirose K, Kim A, Kirkwood K, Maker AV, Corvera C, Nakakura E, Alseidi A, Adam MA| | View in PubMed
  5. Hypertension Requiring Medication Use: a Silent Predictor of Poor Outcomes After Pancreaticoduodenectomy.
    Lin JJ, Conroy PC, Romero-Hernandez F, Yilma M, Feng J, Hirose K, Nakakura E, Maker AV, Corvera C, Kirkwood K, Alseidi A, Adam MA| | View in PubMed
  6. Contemporary Trends in Malignant Peritoneal Mesothelioma: Incidence and Survival in the United States.
    Calthorpe L, Romero-Hernandez F, Miller P, Conroy PC, Hirose K, Kim A, Kirkwood K, Nakakura E, Corvera C, Maker AV, Alseidi A, Adam MA| | View in PubMed
  7. Implementation, evaluation, and modification of a near-peer learning group in graduate surgical education.
    Conroy PC, Mohamedaly S, Karimzada M, Brian R, Im C, Hernandez S, Roman S, Hirose K, Mukhtar R, Kirkwood K, O'Sullivan P, Alseidi A| | View in PubMed
  8. Hand-Assisted Versus Pure Minimally-Invasive Distal Pancreatectomy: Is There a Downside to Lending a Hand?
    Miller PN, Romero-Hernandez F, Conroy P, Calthorpe L, Yilma M, Mohamedaly S, Kelly YM, Feng J, Hirose K, Kirkwood K, Maker AV, Corvera C, Nakakura E, Alseidi A, Adam MA| | View in PubMed
  9. Minimally Invasive Distal Pancreatectomy Techniques: A Contemporary Analysis Exploring Trends, Similarities, and Differences to Open Surgery.
    Romero-Hernandez F, Mohamedaly S, Miller P, Rodriguez N, Calthorpe L, Conroy PC, Ganjouei AA, Hirose K, Maker AV, Nakakura E, Corvera C, Kirkwood KS, Alseidi A, Adam MA| | View in PubMed
  10. Accurate Identification of Mucinous Pancreatic Cystic Lesions Using Small-Volume Analytes.
    Caiazza F, Conroy PC, Ivry SL, York T, Lin J, Hernandez S, Hoffmann TJ, Francis SS, Park WG, Yip-Schneider MT, Schmidt CM, Brand R, Craik CS, Kirkwood K| | View in PubMed
  11. Translation of a Protease Turnover Assay for Clinical Discrimination of Mucinous Pancreatic Cysts.
    Suresh V, Byers K, Rajesh UC, Caiazza F, Zhu G, Craik CS, Kirkwood K, Davisson VJ, Sheik DA| | View in PubMed
  12. Assessing the role of robotic proctectomy in obese patients: a contemporary NSQIP analysis.
    Glencer AC, Lin JA, Trang K, Greenberg A, Kirkwood KS, Adam MA, Sarin A| | View in PubMed
  13. ASO Visual Abstract: Determining Hospital Volume Threshold for the Safety of Minimally Invasive Pancreaticoduodenectomy: A Contemporary Cutpoint Analysis.
    Conroy PC, Calthorpe L, Lin JA, Mohamedaly S, Kim A, Hirose K, Nakakura E, Corvera C, Sosa JA, Sarin A, Kirkwood KS, Alseidi A, Adam MA| | View in PubMed
  14. Determining Hospital Volume Threshold for Safety of Minimally Invasive Pancreaticoduodenectomy: A Contemporary Cutpoint Analysis.
    Conroy PC, Calthorpe L, Lin JA, Mohamedaly S, Kim A, Hirose K, Nakakura E, Corvera C, Sosa JA, Sarin A, Kirkwood KS, Alseidi A, Adam MA| | View in PubMed
  15. The surgical resident experience in serious illness communication: A qualitative needs assessment with proposed solutions.
    Lin JA, Im CJ, O'Sullivan P, Kirkwood KS, Cook AC| | View in PubMed
  16. Burden of Ionizing Radiation in the Diagnosis and Management of Necrotizing Pancreatitis.
    Thiruvengadam NR, Miranda J, Kim C, Behr S, Corvera C, Dai SC, Kirkwood K, Harris HW, Hirose K, Nakakura E, Ostroff JW, Kochman ML, Arain MA| | View in PubMed
  17. Plasma miRNA Biomarkers in Limited Volume Samples for Detection of Early-stage Pancreatic Cancer.
    Dittmar RL, Liu S, Tai MC, Rajapakshe K, Huang Y, Longton G, DeCapite C, Hurd MW, Paris PL, Kirkwood KS, Coarfa C, Maitra A, Brand RE, Killary AM, Sen S| | View in PubMed
  18. Cost-effectiveness of consensus guideline based management of pancreatic cysts: The sensitivity and specificity required for guidelines to be cost-effective.
    Sharib J, Esserman L, Koay EJ, Maitra A, Shen Y, Kirkwood KS, Ozanne EM| | View in PubMed
  19. Theranostic Targeting of CUB Domain Containing Protein 1 (CDCP1) in Pancreatic Cancer.
    Moroz A, Wang YH, Sharib JM, Wei J, Zhao N, Huang Y, Chen Z, Martinko AJ, Zhuo J, Lim SA, Zhang LH, Seo Y, Carlin S, Leung KK, Collisson EA, Kirkwood KS, Wells JA, Evans MJ| | View in PubMed
  20. Ampullary stenosis and choledocholithiasis post Roux-En-Y gastric bypass: challenges of biliary access and intervention.
    Wisneski AD, Carter J, Nakakura EK, Posselt A, Rogers SJ, Cello JP, Arain M, Kirkwood KS, Hirose K, Stewart L, Corvera CU| | View in PubMed
  21. The lysosomal aminopeptidase tripeptidyl peptidase 1 displays increased activity in malignant pancreatic cysts.
    Ivry SL, Knudsen GM, Caiazza F, Sharib JM, Jaradeh K, Ravalin M, O'Donoghue AJ, Kirkwood KS, Craik CS| | View in PubMed
  22. Abdominal Imaging of Pancreatic Cysts and Cyst-Associated Pancreatic Cancer in BRCA1/2 Mutation Carriers: A Retrospective Cross-Sectional Study.
    Cao CX, Sharib JM, Blanco AM, Goldberg D, Bracci P, Mukhtar RA, Esserman LJ, Kirkwood KS| | View in PubMed
  23. Comparison of Tumor Regression Grading of Residual Pancreatic Ductal Adenocarcinoma Following Neoadjuvant Chemotherapy Without Radiation: Would Fewer Tier-Stratification Be Favorable Toward Standardization?
    Kim SS, Ko AH, Nakakura EK, Wang ZJ, Corvera CU, Harris HW, Kirkwood KS, Hirose R, Tempero MA, Kim GE| | View in PubMed
  24. Managing Refractory Postoperative Fistulas as Chronic Wounds Using Video-Assisted Hydrodebridement (VAHD).
    Changala M, Laberge J, Kerlan R, Taylor A, Arain M, Kirkwood K| | View in PubMed
  25. Surgical overtreatment of pancreatic intraductal papillary mucinous neoplasms: Do the 2017 International Consensus Guidelines improve clinical decision making?
    Sharib JM, Fonseca AL, Swords DS, Jaradeh K, Bracci PM, Firpo MA, Hatcher S, Scaife CL, Wang H, Kim GE, Mulvihill SJ, Maitra A, Koay EJ, Kirkwood KS| | View in PubMed
  26. Intraductal Papillary Mucinous Neoplasms of the Pancreas: Current Understanding and Future Directions for Stratification of Malignancy Risk.
    Fonseca AL, Kirkwood K, Kim MP, Maitra A, Koay EJ| | View in PubMed
  27. Gangrenous cholecystitis: innovative laparoscopic techniques to facilitate subtotal fenestrating cholecystectomy when a critical view of safety cannot be achieved.
    Kirkwood R, Damon L, Wang J, Hong E, Kirkwood K| | View in PubMed
  28. Global Protease Activity Profiling Provides Differential Diagnosis of Pancreatic Cysts.
    Ivry SL, Sharib JM, Dominguez DA, Roy N, Hatcher SE, Yip-Schneider MT, Schmidt CM, Brand RE, Park WG, Hebrok M, Kim GE, O'Donoghue AJ, Kirkwood KS, Craik CS| | View in PubMed
  29. Early and accurate diagnosis of pancreatic cancer?
    Sharib J, Kirkwood K| | View in PubMed
  30. Preoperative FOLFIRINOX for borderline resectable pancreatic cancer: Is radiation necessary in the modern era of chemotherapy?
    Kim SS, Nakakura EK, Wang ZJ, Kim GE, Corvera CU, Harris HW, Kirkwood KS, Hirose R, Tempero MA, Ko AH| | View in PubMed
  31. Next generation sequencing of pancreatic cyst fluid microRNAs from low grade-benign and high grade-invasive lesions.
    Wang J, Paris PL, Chen J, Ngo V, Yao H, Frazier ML, Killary AM, Liu CG, Liang H, Mathy C, Bondada S, Kirkwood K, Sen S| | View in PubMed
  32. Serine proteases and protease-activated receptor 2 mediate the proinflammatory and algesic actions of diverse stimulants.
    Cattaruzza F, Amadesi S, Carlsson JF, Murphy JE, Lyo V, Kirkwood K, Cottrell GS, Bogyo M, Knecht W, Bunnett NW| | View in PubMed
  33. Transient receptor potential ankyrin 1 mediates chronic pancreatitis pain in mice.
    Cattaruzza F, Johnson C, Leggit A, Grady E, Schenk AK, Cevikbas F, Cedron W, Bondada S, Kirkwood R, Malone B, Steinhoff M, Bunnett N, Kirkwood KS| | View in PubMed
  34. Informed consent for innovative surgery: a survey of patients and surgeons.
    Lee Char SJ, Hills NK, Lo B, Kirkwood KS| | View in PubMed
  35. Active cathepsins B, L, and S in murine and human pancreatitis.
    Lyo V, Cattaruzza F, Kim TN, Walker AW, Paulick M, Cox D, Cloyd J, Buxbaum J, Ostroff J, Bogyo M, Grady EF, Bunnett NW, Kirkwood KS| | View in PubMed
  36. Ethical management of conflict of interest: proposed standards for academic surgical societies.
    Minter RM, Angelos P, Coimbra R, Dale P, de Vera ME, Hardacre J, Hawkins W, Kirkwood K, Matthews JB, McLoughlin J, Peralta E, Schmidt M, Zhou W, Schwarze ML| | View in PubMed
  37. Serine proteases mediate inflammatory pain in acute pancreatitis.
    Ceppa EP, Lyo V, Grady EF, Knecht W, Grahn S, Peterson A, Bunnett NW, Kirkwood KS, Cattaruzza F| | View in PubMed
  38. Transient receptor potential ion channels V4 and A1 contribute to pancreatitis pain in mice.
    Ceppa E, Cattaruzza F, Lyo V, Amadesi S, Pelayo JC, Poole DP, Vaksman N, Liedtke W, Cohen DM, Grady EF, Bunnett NW, Kirkwood KS| | View in PubMed
  39. Technique for placement of lumboperitoneal catheters using a combined laparoscopic procedure with the Seldinger micropuncture technique.
    Maa J, Carter JT, Kirkwood KS, Gosnell JE, Wang V, McDermott MW| | View in PubMed
  40. MUC5AC, a gel-forming mucin accumulating in gallstone disease, is overproduced via an epidermal growth factor receptor pathway in the human gallbladder.
    Finzi L, Barbu V, Burgel PR, Mergey M, Kirkwood KS, Wick EC, Scoazec JY, Peschaud F, Paye F, Nadel JA, Housset C| | View in PubMed
  41. Trends in laparoscopic splenectomy for massive splenomegaly.
    Grahn SW, Alvarez J, Kirkwood K| | View in PubMed
  42. Calcitonin gene-related peptide partially mediates nociception in acute experimental pancreatitis.
    Wick EC, Pikios S, Grady EF, Kirkwood KS| | View in PubMed
  43. Transient receptor potential vanilloid 1, calcitonin gene-related peptide, and substance P mediate nociception in acute pancreatitis.
    Wick EC, Hoge SG, Grahn SW, Kim E, Divino LA, Grady EF, Bunnett NW, Kirkwood KS| | View in PubMed
  44. Neutral endopeptidase determines the severity of pancreatitis-associated lung injury.
    Day AL, Wick E, Jordan TH, Jaffray CE, Bunnett NW, Grady EF, Kirkwood KS| | View in PubMed
  45. Transient receptor potential vanilloid (TRPV-1) promotes neurogenic inflammation in the pancreas via activation of the neurokinin-1 receptor (NK-1R).
    Hutter MM, Wick EC, Day AL, Maa J, Zerega EC, Richmond AC, Jordan TH, Grady EF, Mulvihill SJ, Bunnett NW, Kirkwood KS| | View in PubMed
  46. Medical versus surgical management of biliary tract disease in pregnancy.
    Lu EJ, Curet MJ, El-Sayed YY, Kirkwood KS| | View in PubMed
  47. Pancreatic resection in the elderly.
    Lightner AM, Glasgow RE, Jordan TH, Krassner AD, Way LW, Mulvihill SJ, Kirkwood KS| | View in PubMed
  48. Activation of nociceptive neurons in T9 and T10 in cerulein pancreatitis.
    Kim EH, Hoge SG, Lightner AM, Grady EF, Coelho AM, Kirkwood KS| | View in PubMed
  49. SIR 2003 film panel case 5: massive hemorrhage from portal vein disruption.
    Kerlan RK, LaBerge JM, Wilson MW, Gordon RL, Kirkwood K, Sawhney R| | View in PubMed
  50. Lovastatin alters biliary lipid composition and dissolves gallstones: a long-term study in prairie dogs.
    Abedin MZ, Narins SC, Park EH, Smith PR, Kirkwood KS| | View in PubMed
  51. Recombinant human neutral endopeptidase ameliorates pancreatic elastase-induced lung injury.
    Lightner AM, Jordan TH, Bunnett NW, Grady EF, Kirkwood KS| | View in PubMed
  52. Pathophysiology of gallstone pancreatitis.
    Lightner AM, Kirkwood KS| | View in PubMed
  53. Deletion of neutral endopeptidase exacerbates intestinal inflammation induced by Clostridium difficile toxin A.
    Kirkwood KS, Bunnett NW, Maa J, Castagliolo I, Liu B, Gerard N, Zacks J, Pothoulakis C, Grady EF| | View in PubMed
  54. NK-1 receptor desensitization and neutral endopeptidase terminate SP-induced pancreatic plasma extravasation.
    Maa J, Grady EF, Kim EH, Yoshimi SK, Hutter MM, Bunnett NW, Kirkwood KS| | View in PubMed
  55. Substance P is a determinant of lethality in diet-induced hemorrhagic pancreatitis in mice.
    Maa J, Grady EF, Yoshimi SK, Drasin TE, Kim EH, Hutter MM, Bunnett NW, Kirkwood KS| | View in PubMed
  56. Substance P mediates inflammatory oedema in acute pancreatitis via activation of the neurokinin-1 receptor in rats and mice.
    Grady EF, Yoshimi SK, Maa J, Valeroso D, Vartanian RK, Rahim S, Kim EH, Gerard C, Gerard N, Bunnett NW, Kirkwood KS| | View in PubMed
  57. Substance P inhibits pancreatic exocrine secretion via a neural mechanism.
    Kirkwood KS, Kim EH, He XD, Calaustro EQ, Domush C, Yoshimi SK, Grady EF, Maa J, Bunnett NW, Debas HT| | View in PubMed
  58. Recent advances. General surgery.
    Corvera CU, Kirkwood KS| | View in PubMed
  59. Prognostic indicators for cancer. Gastric cancer.
    Kirkwood KS, Khitin LM, Barwick KW| | View in PubMed
  60. Substance P and bradykinin stimulate plasma extravasation in the mouse gastrointestinal tract and pancreas.
    Figini M, Emanueli C, Grady EF, Kirkwood K, Payan DG, Ansel J, Gerard C, Geppetti P, Bunnett N| | View in PubMed
  61. Neuroendocrine tumors: common presentations of uncommon diseases.
    Kirkwood KS, Debas HT| | View in PubMed