Education
Education
- 1964-68, University of Oregon, B.S., Biology
- 1969-73, University of Oregon Medical School, M.D., Medicine
Residencies
- 1973-74, Baltimore City Hospital, Intern, Medicine
- 1974-79, Tufts-New England Medical Center, Resident, Surgery
Fellowships
Start Year
1983
End Year
1984
Postdoctoral Training
- 2004, Kaiser Permanente - Endovascular Mini Fellowship, Fellow, Surgery, (Vascular)
Board Certifications
- American Board of Surgery, 1981
- American Board of Surgery, Vascular Surgery, 1990
Clinical Expertise
Abdominal Aortic Aneurysm
Carotid Artery Disease
Chronic Venous Insufficiency
Complex Limb Revascularization
Critical Limb Ischemia
Deep Vein Thrombosis
Diabetic Vascular Disease
Dialysis Access
Endovascular Aneurysm Repair
Mesenteric Artery Disease
Peripheral Artery Disease
Thoracic Aortic Aneurysm
Thoracic Outlet Syndrome
Varicose Veins
Vascular Malformations
Clinical Trials
- Related Conditions: Abdominal Aortic Aneurysm, Aneurysm| Start Date: | End Date:
Program Affiliations
Chief, Vascular Surgery Service - San Francisco VA Medical Center
Grants and Funding
- LIPOPROTEIN ISOLATION FROM SURGICAL SPECIMENS AND PLASMA | NIH | 1988-07-01 - 1993-06-30 | Role: Principal Investigator
- LIPOPROTEIN ISOLATION FROM SURGICAL SPECIMENTS AND PLASM | NIH | 1986-12-01 - 1989-11-30 | Role: Principal Investigator
Publications
MOST RECENT PUBLICATIONS FROM A TOTAL OF 125
- Vascular Anastomoses and Dissection: A Six-Part Simulation Curriculum for Surgical Residents.| | View in PubMed
- Assessment of Surgeon Performance of Advanced Open Surgical Skills Using a Microskills-Based Novel Curriculum.| | View in PubMed
- Eptifibatide bridging therapy for staged carotid artery stenting and cardiac surgery: Safety and feasibility.| | View in PubMed
- Vascular inflammation in a growing iliac artery aneurysm.| | View in PubMed
- Ferumoxytol-enhanced magnetic resonance angiography is a feasible method for the clinical evaluation of lower extremity arterial disease.| | View in PubMed
- Vitamin D deficiency is associated with mortality and adverse vascular access outcomes in patients with end-stage renal disease.| | View in PubMed
- Invited commentary.| | View in PubMed
- Inducible ApoE gene repair in hypomorphic ApoE mice deficient in the low-density lipoprotein receptor promotes atheroma stabilization with a human-like lipoprotein profile.| | View in PubMed
- Assessing the anatomic applicability of the multibranched endovascular repair of thoracoabdominal aortic aneurysm technique.| | View in PubMed
- Macrophage-specific apoE gene repair reduces diet-induced hyperlipidemia and atherosclerosis in hypomorphic Apoe mice.| | View in PubMed
- Efficacy and durability of endovascular thoracoabdominal aortic aneurysm repair using the caudally directed cuff technique.| | View in PubMed
- Apolipoprotein E4 domain interaction accelerates diet-induced atherosclerosis in hypomorphic Arg-61 apoe mice.| | View in PubMed
- Efficacy of optimal long-term management of multiple cardiovascular risk factors (CVD) on walking and quality of life in patients with peripheral artery disease (PAD): protocol for randomized controlled trial.| | View in PubMed
- Polyunsaturated fatty acids and peripheral artery disease.| | View in PubMed
- ApoE suppresses atherosclerosis by reducing lipid accumulation in circulating monocytes and the expression of inflammatory molecules on monocytes and vascular endothelium.| | View in PubMed
- Do microemboli reach the brain penetrating arteries?| | View in PubMed
- The distribution and size of ischemic lesions after carotid artery angioplasty and stenting: evidence for microembolization to terminal arteries.| | View in PubMed
- Preoperative coronary artery revascularization and long-term outcomes following abdominal aortic vascular surgery in patients with abnormal myocardial perfusion scans: a subgroup analysis of the coronary artery revascularization prophylaxis trial.| | View in PubMed
- Long-term follow-up of neck expansion after endovascular aortic aneurysm repair.| | View in PubMed
- Atherosclerotic plaque progression in carotid arteries: monitoring with high-spatial-resolution MR imaging--multicenter trial.| | View in PubMed
- The upside-down zenith stent graft limb.| | View in PubMed
- Distal filtration versus flow reversal: An ex vivo assessment of the choices for carotid embolic protection.| | View in PubMed
- Outcome of renal stenting for renal artery coverage during endovascular aortic aneurysm repair.| | View in PubMed
- Microemboli composed of cholesterol crystals disrupt the blood-brain barrier and reduce cognition.| | View in PubMed
- Branched stent-grafts: will these become the new standard?| | View in PubMed
- An experimental model of lacunar infarction: embolization of microthrombi.| | View in PubMed
- High-resolution CT imaging of carotid artery atherosclerotic plaques.| | View in PubMed
- Predictors and outcomes of a perioperative myocardial infarction following elective vascular surgery in patients with documented coronary artery disease: results of the CARP trial.| | View in PubMed
- Endovascular treatment of thoracoabdominal aortic aneurysms.| | View in PubMed
- Clinical factors associated with long-term mortality following vascular surgery: outcomes from the Coronary Artery Revascularization Prophylaxis (CARP) Trial.| | View in PubMed
- Atheroembolism during percutaneous renal artery revascularization.| | View in PubMed
- Postprocedural microembolic events following carotid surgery and carotid angioplasty and stenting.| | View in PubMed
- Subclinical embolization after carotid artery stenting: new lesions on diffusion-weighted magnetic resonance imaging occur postprocedure.| | View in PubMed
- MRI of geometric and compositional features of vulnerable carotid plaque.| | View in PubMed
- Long-term outcome and reintervention after endovascular abdominal aortic aneurysm repair using the Zenith stent graft.| | View in PubMed
- The effect of magnetic resonance imaging on stainless-steel Z-stent-based abdominal aortic prosthesis.| | View in PubMed
- Unmasking complicated atherosclerotic plaques on carotid magnetic resonance angiography: a report of three cases.| | View in PubMed
- Ezetimibe inhibits the incorporation of dietary oxidized cholesterol into lipoproteins.| | View in PubMed
- Postoperative outcomes for patients undergoing elective revascularization for critical limb ischemia and intermittent claudication: a subanalysis of the Coronary Artery Revascularization Prophylaxis (CARP) trial.| | View in PubMed
- Adjunctive primary stenting of Zenith endograft limbs during endovascular abdominal aortic aneurysm repair: implications for limb patency.| | View in PubMed
- The role of dietary oxidized cholesterol and oxidized fatty acids in the development of atherosclerosis.| | View in PubMed
- Aortoiliac occlusive disease in patients with known or suspected peripheral vascular disease: safety and efficacy of gadofosveset-enhanced MR angiography--multicenter comparative phase III study.| | View in PubMed
- Atheroemboli during renal artery angioplasty: an ex vivo study.| | View in PubMed
- Credentialing for carotid artery stenting.| | View in PubMed
- Coronary-artery revascularization before elective major vascular surgery.| | View in PubMed
- Transport of contrast agents in contrast-enhanced magnetic resonance angiography.| | View in PubMed
- Current status of carotid imaging by MRA.| | View in PubMed
- Impact of surgeon and surgical center characteristics on choice of permanent vascular access.| | View in PubMed
- Cerebral ischemia and infarction from atheroemboli <100 microm in Size.| | View in PubMed
- Contrast material-enhanced MRA overestimates severity of carotid stenosis, compared with 3D time-of-flight MRA.| | View in PubMed
- Double-lumen carotid plaque: a morbid configuration.| | View in PubMed
- Biochemical characterization of atherosclerotic plaque constituents using FTIR spectroscopy and histology.| | View in PubMed
- Oxidized cholesterol in the diet is a source of oxidized lipoproteins in human serum.| | View in PubMed
- Hepatic endosomal trafficking of lipoprotein-bound endotoxin in rats.| | View in PubMed
- Rupture rate of large abdominal aortic aneurysms in patients refusing or unfit for elective repair.| | View in PubMed
- Immediate repair compared with surveillance of small abdominal aortic aneurysms.| | View in PubMed
- Expansion rates and outcomes for the 3.0-cm to the 3.9-cm infrarenal abdominal aortic aneurysm.| | View in PubMed
- Major carotid plaque surface irregularities correlate with neurologic symptoms.| | View in PubMed
- Structure of plaque at carotid bifurcation: high-resolution MRI with histological correlation.| | View in PubMed
- Endoleak after endovascular repair of abdominal aortic aneurysm.| | View in PubMed
- Detection of clinically silent infarcts after carotid endarterectomy by use of diffusion-weighted imaging.| | View in PubMed
- Atheroemboli to the brain: size threshold for causing acute neuronal cell death.| | View in PubMed
- Oxidized cholesterol in the diet accelerates the development of atherosclerosis in LDL receptor- and apolipoprotein E-deficient mice.| | View in PubMed
- Endovascular aneurysm repair in high-risk patients.| | View in PubMed
- Oxidized cholesterol in the diet accelerates the development of aortic atherosclerosis in cholesterol-fed rabbits.| | View in PubMed
- Secretory sphingomyelinase, a product of the acid sphingomyelinase gene, can hydrolyze atherogenic lipoproteins at neutral pH. Implications for atherosclerotic lesion development.| | View in PubMed
- Exposure to cigarette smoke delays the plasma clearance of chylomicrons and chylomicron remnants in rats.| | View in PubMed
- A blinded trial of local recombinant tissue factor pathway inhibitor versus either local or systemic heparin in a vein bypass model.| | View in PubMed
- Rabbit aorta and human atherosclerotic lesions hydrolyze the sphingomyelin of retained low-density lipoprotein. Proposed role for arterial-wall sphingomyelinase in subendothelial retention and aggregation of atherogenic lipoproteins.| | View in PubMed
- Sepsis increases endocytosis of endotoxin into hepatocytes.| | View in PubMed
- Oxidized lipids in the diet accelerate the development of fatty streaks in cholesterol-fed rabbits.| | View in PubMed
- Oxidized lipids in the diet are incorporated by the liver into very low density lipoprotein in rats.| | View in PubMed
- Triglyceride-rich lipoproteins prevent septic death in rats.| | View in PubMed
- Role for circulating lipoproteins in protection from endotoxin toxicity.| | View in PubMed
- Assessment of carotid artery stenosis by ultrasonography, conventional angiography, and magnetic resonance angiography: correlation with ex vivo measurement of plaque stenosis.| | View in PubMed
- Triglyceride-rich lipoproteins improve survival when given after endotoxin in rats.| | View in PubMed
- Oxidized lipids in the diet are a source of oxidized lipid in chylomicrons of human serum.| | View in PubMed
- Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque.| | View in PubMed
- Endotoxin and cytokines increase hepatic messenger RNA levels and serum concentrations of apolipoprotein J (clusterin) in Syrian hamsters.| | View in PubMed
- The protective effect of serum lipoproteins against bacterial lipopolysaccharide.| | View in PubMed
- Comparison of cardiac morbidity rates between aortic and infrainguinal operations: two-year follow-up. Study of Perioperative Ischemia Research Group.| | View in PubMed
- Limb salvage and wound coverage in patients with large ischemic ulcers: a multidisciplinary approach with revascularization and free tissue transfer.| | View in PubMed
- Chylomicrons enhance endotoxin excretion in bile.| | View in PubMed
- Cigarette smoke alters chylomicron metabolism in rats.| | View in PubMed
- The effect of oxidized lipids in the diet on serum lipoprotein peroxides in control and diabetic rats.| | View in PubMed
- Chylomicrons alter the fate of endotoxin, decreasing tumor necrosis factor release and preventing death.| | View in PubMed
- Effect of dietary lipid peroxides on metabolism of serum chylomicrons in rats.| | View in PubMed
- Adverse effects of aspirin in the treatment of asymptomatic carotid artery stenosis. The VA Cooperative Asymptomatic Carotid Artery Stenosis Study Group.| | View in PubMed
- Magnetic resonance angiography of the carotid artery combining two- and three-dimensional acquisitions.| | View in PubMed
- Assessment of carotid artery stenosis by MR angiography: comparison with x-ray angiography and color-coded Doppler ultrasound.| | View in PubMed
- The effect of lipid lowering on the incidence of recurrent carotid stenosis.| | View in PubMed
- Inhibition of injury induced intimal hyperplasia by saralasin in rats.| | View in PubMed
- Relation of plasma lipid and apoprotein levels to progressive intimal hyperplasia after arterial endarterectomy.| | View in PubMed
- Chylomicron and chylomicron remnant metabolism in STZ-induced diabetic rats.| | View in PubMed
- Comparison of cardiac morbidity between aortic and infrainguinal operations. Study of Perioperative Ischemia (SPI) Research Group.| | View in PubMed
- Regulation of hepatic lipid metabolism by cytokines that induce the acute phase response.| | View in PubMed
- Chylomicrons can inhibit endotoxin activity in vitro.| | View in PubMed
- Connective tissue proteinases and inhibitors in abdominal aortic aneurysms. Involvement of the vasa vasorum in the pathogenesis of aortic aneurysms.| | View in PubMed
- A prospective randomized trial of autologous platelet-derived wound healing factors for treatment of chronic nonhealing wounds: a preliminary report.| | View in PubMed
- Chronic visceral ischemia. Three decades of progress.| | View in PubMed
- Detection of endotoxin in triglyceride-rich lipoproteins in vitro.| | View in PubMed
- Lower-extremity vascular grafts placed for peripheral vascular disease: prospective evaluation with duplex Doppler sonography.| | View in PubMed
- Dietary eicosapentaenoic acid and docosahexaenoic acid from fish oil. Their incorporation into advanced human atherosclerotic plaques.| | View in PubMed
- Simultaneous resection of renal carcinoma and abdominal aortic aneurysm.| | View in PubMed
- Basic data related to lipid abnormalities in peripheral vascular disease.| | View in PubMed
- The "natural history" of segmental wall motion abnormalities in patients undergoing noncardiac surgery. S.P.I. Research Group.| | View in PubMed
- Human very low density lipoproteins and chylomicrons can protect against endotoxin-induced death in mice.| | View in PubMed
- Testosterone regulates metabolism of plasma chylomicrons in rats.| | View in PubMed
- Recurrent carotid stenosis: a consequence of local or systemic factors? The influence of unrepaired technical defects.| | View in PubMed
- Recombinant human tissue-type plasminogen activator is an effective agent for thrombolysis of peripheral arteries and bypass grafts: preliminary report.| | View in PubMed
- Saphenous vein bypass to pedal arteries. An aggressive strategy for foot salvage.| | View in PubMed
- Identification of aortic thrombus by magnetic resonance imaging.| | View in PubMed
- "Angiography" by magnetic resonance imaging: detailed vascular anatomy without ionizing radiation or contrast media.| | View in PubMed
- Particle size distribution of lipoproteins from human atherosclerotic plaque: a preliminary report.| | View in PubMed
- Preoperative balloon-tipped catheter placement for proximal control in visceral artery aneurysm surgery.| | View in PubMed
- Comparative effects of hypertension and nicotine on injury-induced myointimal thickening.| | View in PubMed
- Hypercholesterolemia and early restenosis after carotid endarterectomy.| | View in PubMed
- Recurrent carotid stenosis: operative strategy and late results.| | View in PubMed
- Cholesterol lowering with total parenteral nutrition (TPN)| | View in PubMed
- Ischemia of the upper extremity: significance of proximal arterial disease.| | View in PubMed
- Durability of endarterectomy and antegrade grafts in the treatment of chronic visceral ischemia.| | View in PubMed
- Composition and metabolism of symptomatic distal aortic plaque.| | View in PubMed
- Direct revascularization for occlusion of the trunks of the aortic arch.| | View in PubMed
- Lipids of human atherosclerotic plaques and xanthomas: clues to the mechanism of plaque progression.| | View in PubMed
- Colestipol plus nicotinic acid in treatment of heterozygous familial hypercholesterolaemia.| | View in PubMed