University of California San Francisco

Joseph Cuschieri-lg-headshot
Joseph
Cuschieri
MD, FACS

Division of General Surgery  
Professor of Surgery   
Chief of Surgery Zuckerberg San Francisco General Hospital Trauma and Surgical  
Critical Care at Zuckerberg San Francisco General Hospital  
Trauma Medical Director at Zuckerberg San Francisco General Hospital

Address

1001 Potrero Avenue, #3A25
San Francisco, CA 94110
United States

ORCID: 0000-0003-1456-6841

Biography

Joseph Cuschieri M.D. earned his Bachelor of Science Degree in Biochemistry from the University of Michigan, and his Medical Degree from Wayne State University School of Medicine.  He completed his general surgery residence and surgical critical care fellowship at Henry Ford Hospital in Detroit, Michigan.  Upon completion of his clinical training, he completed a 2-year NIH T32 Fellowship in the field of Trauma/Burn/Inflammation.

Dr. Cuschieri is certified by the American Board of Surgery in General Surgery with subspecialty certification in Surgical Critical Care.

Upon completion of his fellowship in 2002, Dr. Cuschieri joined the faculty at the University of Cincinnati School of Medicine.  After a couple of years he left Cincinnati and returned to Seattle, joining the faculty at the University of Washington School of Medicine where he served as the Medical Director of Surgical Critical Care, Interim Associate Medical Director of Critical Care, Associate Medical Director of Surgical Services, and Program Director of Surgical Critical Care.  Dr. Cuschieri left Washington and came to UCSF in 2021 to join the faculty in the Department of Surgery as Professor and Trauma Medical Director at the Zuckerberg San Francisco General Hospital and Trauma Center.

Dr. Cuschieri currently serves as Principal Investigator, Co-Principle investigator, or Co-Investigator on 3 federally funded grants and has authored or co-authored over 170 peer-reviewed articles and more than 10 book chapters.  His national service includes active participation in major trauma, critical care, and surgical societies including the American Association for the Surgery of Trauma and the Society of Surgical Critical Care Program Directors.  He also serves on the Editorial Board for the Journal of Trauma and Acute Care Surgery.

Awards & Honors

Award Conferred By Date
John K. Stevenson Faculty Teaching Award in Surgery University of Washington School of Medicine 2019
CDC HA-VTE Prevention Challenge Champion Centers of Disease Control 2015
Castle Connelly Top Doctors Castle Connelly Inc. 2006/2021
Joseph Sussman Memorial Award Surgical Infection Society 2006

Education

Institution Degree Dept or School End Date
University of California Diversity, Equity, and Inclusion Champion Training 09/2021
University of Washington T32 Trauma/Burn/Inflammation 6/2002
Henry Ford Hospital Medical Center General Surgery 6/2000
Henry Ford Hospital Medical Center Surgical Critical Care 6/1998
Wayne State University School of Medicine MD Medicine 6/1994
University of Michigan BS Biochemistry 6/1990

In the News

Dr. Joseph Cuschieri Appointed Chief of Surgery at ZSFG
January, 09, 2023 | UCSF Department of Surgery

Grants and Funding

  • Surgery Research Training Program | NIH | 2017-07-01 - 2022-06-30 | Role: Co-Investigator
  • Validation of a Genomics Based Prognostic in Severe Trauma | NIH | 2013-06-01 - 2017-04-30 | Role: Co-Investigator
  • A Randomzied Phase II Trial of CMV Prevention in Acute Lung Injury | NIH | 2010-06-01 - 2016-12-31 | Role: Co-Investigator
  • POSTDOCTORAL TRAINING | NIH | 1975-07-01 - 2015-06-30 | Role: Co-Investigator
  • Bedside Genomics in Severe Trauma | NIH | 2012-09-25 - 2014-08-31 | Role: Co-Investigator
  • Planning a Multi-Center Trial of Interferon-gamma in Trauma Patients | NIH | 2012-09-01 - 2014-08-31 | Role: Co-Investigator
  • SIS multicenter study of duration of antibiotics for intraabdominal infection | NIH | 2007-09-11 - 2014-08-31 | Role: Co-Investigator
  • Inflammation and the Host Responses to Injury | NIH | 2000-09-01 - 2013-08-31 | Role: Co-Investigator
  • TRAUMA &SEPSIS INDUCED CHANGES IN IMMUNE CELL MEMBRANE RECEPTOR TRAFFICKING | NIH | 2007-09-01 - 2013-06-30 | Role: Principal Investigator
  • Hypertonic Modulation of Inflammation following Injury | NIH | 2007-06-11 - 2012-11-30 | Role: Co-Investigator

Research Narrative

Dr. Cuschieri is a clinical and translational researcher who has worked to decipher the effects of initial injury on subsequent alterations immune function, and development of evidence based practices to improve care of injured and septic patients.  His main research focus is in the fields of polytrauma, hemorrhagic shock and neurotrauma with a specific interest in long-term outcomes following injury. From a critical care perspective, his main focus has been on organ support in the critically ill and septic patient.

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 188
  1. Insights from CTTACC: immune system reset by cellular therapies for chronic illness after trauma, infection, and burn.
    Bertram K, Cox C, Alam H, Lowell C, Cuschieri J, Parekkadan B, Pati S| | View in PubMed
  2. Effect of Aspirin Versus Low-Molecular-Weight Heparin Thromboprophylaxis on Medication Satisfaction and Out-of-Pocket Costs: A Secondary Analysis of a Randomized Clinical Trial.
    O'Hara NN, Frey KP, Stein DM, Levy JF, Slobogean GP, Castillo R, Firoozabadi R, Karunakar MA, Gary JL, Obremskey WT, Seymour RB, Cuschieri J, Mullins CD, O'Toole RV, METRC| | View in PubMed
  3. Risk-stratified thromboprophylaxis effects of aspirin versus low-molecular-weight heparin in orthopaedic trauma patients: a secondary analysis of the PREVENT CLOT trial.
    O'Hara NN, O'Toole RV, Frey KP, Castillo RC, Cuschieri J, Haut ER, Slobogean GP, Firoozabadi R, Christmas A, Obremskey WT, Carlini AR, Gaski G, Kutcher ME, Marvel D, Stein DM, Major Extremity Trauma Research Consortium (METRC)| | View in PubMed
  4. Screening for Intimate Partner Violence in Trauma: Results of a Quality Improvement Project.
    Decker H, Schwab M, Shao S, Kaki D, Melhado C, Cuschieri J, Bongiovanni T| | View in PubMed
  5. The injured monocyte: The link to chronic critical illness and mortality following injury.
    Cuschieri J, Kornblith L, Pati S, Piliponsky A| | View in PubMed
  6. Trial Participation and Outcomes Among English-Speaking and Spanish-Speaking Patients With Appendicitis Randomized to Antibiotics: A Secondary Analysis of the CODA Randomized Clinical Trial.
    Serrano E, Voldal EC, Machado-Aranda D, DeUgarte DA, Kao L, Drake T, Winchell R, Cuschieri J, Krishnadasan A, Talan DA, Siparsky N, Ayoung-Chee P, Self WH, McGonagill P, Mandell KA, Liang MK, Dodwad SJ, Thompson CM, Padilla RM, Fleischman R, Price TP, Jones A, Bernardi K, Garcia L, Evans HL, Sanchez SE, Odom S, Comstock BA, Heagerty PJ, Lawrence SO, Monsell SE, Fannon EEC, Kessler LG, Flum DR, Davidson GH, Writing Group for the CODA Collaborative| | View in PubMed
  7. Organ donation in the surgical ICU: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document.
    Seshadri A, Cuschieri J, Kaups KL, Knowlton LM, Kutcher ME, Pathak A, Rappold J, Rinderknecht T, Stein DM, Young J, Michetti CP| | View in PubMed
  8. Developing a National Trauma Research Action Plan: Results from the long-term outcomes research gap Delphi survey.
    Herrera-Escobar JP, Reidy E, Phuong J, Brasel KJ, Cuschieri J, Fallat M, Potter BK, Price MA, Bulger EM, Haider AH, Bonne S, Brasel KJ, Cuschieri J, de Roon-Cassini T, Dicker RA, Fallat M, Ficke JR, Gabbe B, Gibran NS, Heinemann AW, Ho V, Kao LS, Kellam JF, Kurowski BG, Levy-Carrick NC, Livingston D, Mandell SP, Manley GT, Michetti CP, Miller AN, Newcomb A, Okonkwo D, Potter BK, Seamon M, Stein D, Wagner AK, Whyte J, Yonclas P, Zatzick D, Zielinski MD, NTRAP Long-term Outcomes Panel| | View in PubMed
  9. Alcohol Intoxication Is Associated With Bladder Injury and Bladder Surgical Repair in Patients Sustaining Motor Vehicle Collisions.
    Lui JL, Hakam N, Shaw NM, Cuschieri J, Abbasi B, Breyer BN| | View in PubMed
  10. Management of Decompensated Cirrhosis in the Surgical ICU: an American Association for the Surgery of Trauma Critical Care Committee Clinical Consensus Document.
    Seshadri A, Appelbaum R, Carmichael SP, Cuschieri J, Hoth J, Kaups KL, Kodadek L, Kutcher ME, Pathak A, Rappold J, Rudnick SR, Michetti CP| | View in PubMed
  11. Perception of Treatment Success and Impact on Function with Antibiotics or Appendectomy for Appendicitis: A Randomized Clinical Trial with an Observational Cohort.
    Thompson CM, Voldal EC, Davidson GH, Sanchez SE, Ayoung-Chee P, Victory J, Guiden M, Bizzell B, Glaser J, Hults C, Price TP, Siparsky N, Ohe K, Mandell KA, DeUgarte DA, Kaji AH, Uribe L, Kao LS, Mueck KM, Farjah F, Self WH, Clark S, Drake FT, Fischkoff K, Minko E, Cuschieri J, Faine B, Skeete DA, Dhanani N, Liang MK, Krishnadasan A, Talan DA, Fannon E, Kessler LG, Comstock BA, Heagerty PJ, Monsell SE, Lawrence SO, Flum DR, Lavallee DC, Writing Group for the CODA Collaborative| | View in PubMed
  12. Analysis of Outcomes Associated With Outpatient Management of Nonoperatively Treated Patients With Appendicitis.
    Writing Group for the CODA Collaborative, Talan DA, Moran GJ, Krishnadasan A, Monsell SE, Faine BA, Uribe L, Kaji AH, DeUgarte DA, Self WH, Shapiro NI, Cuschieri J, Glaser J, Park PK, Price TP, Siparsky N, Sanchez SE, Machado-Aranda DA, Victory J, Ayoung-Chee P, Chiang W, Corsa J, Evans HL, Ferrigno L, Garcia L, Hatch Q, Horton MD, Johnson J, Jones A, Kao LS, Kelly A, Kim D, Kutcher ME, Liang MK, Maghami N, McGrane K, Minko E, Mohr C, Neufeld M, Patton JH, Rog C, Rushing A, Sabbatini AK, Salzberg M, Thompson CM, Tichter A, Wisler J, Bizzell B, Fannon E, Lawrence SO, Voldal EC, Lavallee DC, Comstock BA, Heagerty PJ, Davidson GH, Flum DR, Kessler LG| | View in PubMed
  13. Self-selection vs Randomized Assignment of Treatment for Appendicitis.
    Writing Group for the CODA Collaborative, Davidson GH, Monsell SE, Evans H, Voldal EC, Fannon E, Lawrence SO, Krishnadasan A, Talan DA, Bizzell B, Heagerty PJ, Comstock BA, Lavallee DC, Villegas C, Winchell R, Thompson CM, Self WH, Kao LS, Dodwad SJ, Sabbatini AK, Droullard D, Machado-Aranda D, Gibbons MM, Kaji AH, DeUgarte DA, Ferrigno L, Salzberg M, Mandell KA, Siparsky N, Price TP, Raman A, Corsa J, Wisler J, Ayoung-Chee P, Victory J, Jones A, Kutcher M, McGrane K, Holihan J, Liang MK, Cuschieri J, Johnson J, Fischkoff K, Drake FT, Sanchez SE, Odom SR, Kessler LG, Flum DR| | View in PubMed
  14. Postinjury platelet aggregation and venous thromboembolism.
    Matthay ZA, Hellmann ZJ, Nunez-Garcia B, Fields AT, Cuschieri J, Neal MD, Berger JS, Luttrell-Williams E, Knudson MM, Cohen MJ, Callcut RA, Kornblith LZ| | View in PubMed
  15. Developing a National Trauma Research Action Plan: Results from the acute resuscitation, initial patient evaluation, imaging, and management research gap Delphi survey.
    Costantini TW, Galante JM, Braverman MA, Phuong J, Price MA, Cuschieri J, Godat LN, Holcomb JB, Coimbra R, Bulger EM, NTRAP Acute Resuscitation Panel| | View in PubMed
  16. Nonoperative Management in Blunt Splenic Trauma: Can Shock Index Predict Failure?
    Senekjian L, Robinson BRH, Meagher AD, Gross JA, Maier RV, Bulger EM, Arbabi S, Cuschieri J| | View in PubMed
  17. Patient Factors Associated With Appendectomy Within 30 Days of Initiating Antibiotic Treatment for Appendicitis.
    Writing Group for the CODA Collaborative, Monsell SE, Voldal EC, Davidson GH, Fischkoff K, Coleman N, Bizzell B, Price T, Narayan M, Siparsky N, Thompson CM, Ayoung-Chee P, Odom SR, Sanchez S, Drake FT, Johnson J, Cuschieri J, Evans HL, Liang MK, McGrane K, Hatch Q, Victory J, Wisler J, Salzberg M, Ferrigno L, Kaji A, DeUgarte DA, Gibbons MM, Alam HB, Scott J, Kao LS, Self WH, Winchell RJ, Villegas CM, Talan DA, Kessler LG, Lavallee DC, Krishnadasan A, Lawrence SO, Comstock B, Fannon E, Flum DR, Heagerty PJ| | View in PubMed
  18. A new trauma frontier: Exploratory pilot study of platelet transcriptomics in trauma patients.
    Fields AT, Lee MC, Mayer F, Santos YA, Bainton CMV, Matthay ZA, Callcut RA, Mayer N, Cuschieri J, Kober KM, Bainton RJ, Kornblith LZ| | View in PubMed
  19. Utility and Outcome of Angioembolization for High-Grade Renal Trauma Management in a Large Hospital-Based Trauma Registry.
    Hakam N, Amend GM, Nabavizadeh B, Allen IE, Shaw NM, Cuschieri J, Wilson MW, Stein DM, Breyer BN| | View in PubMed
  20. Respiratory events after intensive care unit discharge in trauma patients: Epidemiology, outcomes, and risk factors.
    Rosen JE, Bulger EM, Cuschieri J| | View in PubMed
  21. Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score.
    COVIDSurg Collaborative| | View in PubMed
  22. Antibiotics versus Appendectomy for Acute Appendicitis - Longer-Term Outcomes.
    CODA Collaborative, Davidson GH, Flum DR, Monsell SE, Kao LS, Voldal EC, Heagerty PJ, Fannon E, Lavallee DC, Bizzell B, Lawrence SO, Comstock BA, Krishnadasan A, Winchell RJ, Self WH, Thompson CM, Farjah F, Park PK, Alam HB, Saltzman D, Moran GJ, Kaji AH, DeUgarte DA, Salzberg M, Ferrigno L, Mandell KA, Price TP, Siparsky N, Glaser J, Ayoung-Chee P, Chiang W, Victory J, Chung B, Carter DW, Kutcher ME, Jones A, Holihan J, Liang MK, Faine BA, Cuschieri J, Evans HL, Johnson J, Patton JH, Coleman N, Fischkoff K, Drake FT, Sanchez SE, Parsons C, Odom SR, Kessler LG, Talan DA| | View in PubMed
  23. Chronic critical illness after hypothermia in trauma patients.
    Miranda D, Maine R, Cook M, Brakenridge S, Moldawer L, Arbabi S, O'Keefe G, Robinson B, Bulger EM, Maier R, Cuschieri J| | View in PubMed
  24. Multi-center validation of the Bowel Injury Predictive Score (BIPS) for the early identification of need to operate in blunt bowel and mesenteric injuries.
    Wandling M, Cuschieri J, Kozar R, O'Meara L, Celii A, Starr W, Burlew CC, Todd SR, de Leon A, McIntyre RC, Urban S, Biffl WL, Bayat D, Dunn J, Peck K, Rooney AS, Kornblith LZ, Callcut RA, Lollar DI, Ambroz E, Leichtle SW, Aboutanos MB, Schroeppel T, Hennessy EA, Russo R, McNutt M| | View in PubMed
  25. The Covid-19 Pandemic: Lessons Learned for Sustained Trauma Preparedness and Responses.
    Cuschieri J, Robinson B, Lynch J, Mitchell S, Arbabi S, Bryson C, Sayre M, Maier RV, Bulger E| | View in PubMed
  26. Aspirin versus anticoagulation for stroke prophylaxis in blunt cerebrovascular injury: a propensity-matched retrospective cohort study.
    Bonow RH, Witt CE, Mossa-Basha M, Cuschieri J, Arbabi S, Vavilala MS, Rivara FP, Chesnut RM| | View in PubMed
  27. PREVENTion of CLots in Orthopaedic Trauma (PREVENT CLOT): a randomised pragmatic trial protocol comparing aspirin versus low-molecular-weight heparin for blood clot prevention in orthopaedic trauma patients.
    O'Toole RV, Stein DM, Frey KP, O'Hara NN, Scharfstein DO, Slobogean GP, Taylor TJ, Haac BE, Carlini AR, Manson TT, Sudini K, Mullins CD, Wegener ST, Firoozabadi R, Haut ER, Bosse MJ, Seymour RB, Holden MB, Gitajn IL, Goldhaber SZ, Eastman AL, Jurkovich GJ, Vallier HA, Gary JL, Kleweno CP, Cuschieri J, Marvel D, Castillo RC, METRC| | View in PubMed
  28. Venous thromboembolism prophylaxis in the trauma intensive care unit: an American Association for the Surgery of Trauma Critical Care Committee Clinical Consensus Document.
    Rappold JF, Sheppard FR, Carmichael Ii SP, Cuschieri J, Ley E, Rangel E, Seshadri AJ, Michetti CP| | View in PubMed
  29. Distinct immunologic endotypes are associated with clinical trajectory after severe blunt trauma and hemorrhagic shock.
    Brakenridge SC, Wang Z, Cox M, Raymond S, Hawkins R, Darden D, Ghita G, Brumback B, Cuschieri J, Maier RV, Moore FA, Mohr AM, Efron PA, Moldawer LL| | View in PubMed
  30. Persistent metabolomic alterations characterize chronic critical illness after severe trauma.
    Horn DL, Bettcher LF, Navarro SL, Pascua V, Neto FC, Cuschieri J, Raftery D, O'Keefe GE| | View in PubMed
  31. Changes in error patterns in unanticipated trauma deaths during 20 years: In pursuit of zero preventable deaths.
    LaGrone LN, McIntyre L, Riggle A, Robinson BRH, Maier RV, Bulger E, Cuschieri J| | View in PubMed
  32. A Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis.
    CODA Collaborative, Flum DR, Davidson GH, Monsell SE, Shapiro NI, Odom SR, Sanchez SE, Drake FT, Fischkoff K, Johnson J, Patton JH, Evans H, Cuschieri J, Sabbatini AK, Faine BA, Skeete DA, Liang MK, Sohn V, McGrane K, Kutcher ME, Chung B, Carter DW, Ayoung-Chee P, Chiang W, Rushing A, Steinberg S, Foster CS, Schaetzel SM, Price TP, Mandell KA, Ferrigno L, Salzberg M, DeUgarte DA, Kaji AH, Moran GJ, Saltzman D, Alam HB, Park PK, Kao LS, Thompson CM, Self WH, Yu JT, Wiebusch A, Winchell RJ, Clark S, Krishnadasan A, Fannon E, Lavallee DC, Comstock BA, Bizzell B, Heagerty PJ, Kessler LG, Talan DA| | View in PubMed
  33. Society of Interventional Radiology Clinical Practice Guideline for Inferior Vena Cava Filters in the Treatment of Patients with Venous Thromboembolic Disease: Developed in collaboration with the American College of Cardiology, American College of Chest P
    Kaufman JA, Barnes GD, Chaer RA, Cuschieri J, Eberhardt RT, Johnson MS, Kuo WT, Murin S, Patel S, Rajasekhar A, Weinberg I, Gillespie DL| | View in PubMed
  34. Authors' reply: Understanding state-level Medicaid expansion in the context of nationwide data.
    Scott JW, Shrime MG, Stewart BT, Arbabi S, Bulger EM, Cuschieri J, Maier RV, Robinson BRH| | View in PubMed
  35. Splenic artery angioembolization for high-grade splenic injury: Are we wasting money?
    Senekjian L, Cuschieri J, Robinson BRH| | View in PubMed
  36. Predictors of mortality, limb loss, and discharge disposition at admission among patients with necrotizing skin and soft tissue infections.
    Horn DL, Shen J, Roberts E, Wang TN, Li KS, O'Keefe GE, Cuschieri J, Bulger EM, Robinson BRH| | View in PubMed
  37. Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study.
    COVIDSurg Collaborative| | View in PubMed
  38. Prospective Validation of a Transcriptomic Metric in Severe Trauma.
    Raymond SL, Hawkins RB, Wang Z, Mira JC, Stortz JA, Han F, Lanz JD, Hennessy LV, Brumback BA, Baker HV, Efron PA, Brakenridge SC, Xiao W, Tompkins RG, Cuschieri J, Moore FA, Maier RV, Moldawer LL| | View in PubMed
  39. Proceedings from the Consensus Conference on Trauma Patient-Reported Outcome Measures.
    Sakran JV, Ezzeddine H, Schwab CW, Bonne S, Brasel KJ, Burd RS, Cuschieri J, Ficke J, Gaines BA, Giacino JT, Gibran NS, Haider A, Hall EC, Herrera-Escobar JP, Joseph B, Kao L, Kurowski BG, Livingston D, Mandell SP, Nehra D, Sarani B, Seamon M, Yonclas P, Zarzaur B, Stewart R, Bulger E, Nathens AB, Patient Reported Outcome Consortium| | View in PubMed
  40. Contemporary hemodynamic monitoring, fluid responsiveness, volume optimization, and endpoints of resuscitation: an AAST critical care committee clinical consensus.
    Martin ND, Codner P, Greene W, Brasel K, Michetti C, AAST Critical Care Committee| | View in PubMed
  41. Lifting the burden: State Medicaid expansion reduces financial risk for the injured.
    Scott JW, Shrime MG, Stewart BT, Arbabi S, Bulger EM, Cuschieri J, Maier RV, Robinson BRH| | View in PubMed
  42. Cell-free nuclear, but not mitochondrial, DNA concentrations correlate with the early host inflammatory response after severe trauma.
    Stortz JA, Hawkins RB, Holden DC, Raymond SL, Wang Z, Brakenridge SC, Cuschieri J, Moore FA, Maier RV, Moldawer LL, Efron PA| | View in PubMed
  43. Ventilator-associated events, not ventilator-associated pneumonia, is associated with higher mortality in trauma patients.
    Meagher AD, Lind M, Senekjian L, Iwuchukwu C, Lynch JB, Cuschieri J, Robinson BRH| | View in PubMed
  44. Authors Response to Commentary on our Manuscript.
    Cook MR, Cuschieri J| | View in PubMed
  45. Trauma Surgeon and Palliative Care Physician Attitudes Regarding Goals-of-Care Delineation for Injured Geriatric Patients.
    Cunningham HB, Scielzo SA, Nakonezny PA, Bruns BR, Brasel KJ, Inaba K, Brakenridge SC, Kerby JD, Joseph BA, Mohler MJ, Cuschieri J, Paulk ME, Ekeh AP, Madni TD, Taveras LR, Imran JB, Wolf SE, Phelan HA| | View in PubMed
  46. Burn Surgeon and Palliative Care Physician Attitudes Regarding Goals of Care Delineation for Burned Geriatric Patients.
    Cunningham HB, Scielzo SA, Nakonezny PA, Bruns BR, Brasel KJ, Inaba K, Brakenridge SC, Kerby JD, Joseph BA, Mohler MJ, Cuschieri J, Paulk ME, Ekeh AP, Madni TD, Taveras LR, Imran JB, Wolf SE, Phelan HA| | View in PubMed
  47. Decreased Risk of Delirium With Use of Regional Analgesia in Geriatric Trauma Patients With Multiple Rib Fractures.
    O'Connell KM, Quistberg DA, Tessler R, Robinson BRH, Cuschieri J, Maier RV, Rivara FP, Vavilala MS, Bhalla PI, Arbabi S| | View in PubMed
  48. Unique Uses of Cooling Strategies.
    Lyden P, Paul J, Yokobori S, Cuschieri J| | View in PubMed
  49. Duration of Respiratory Failure After Trauma Is Not Associated With Increased Long-Term Mortality.
    Cook MR, O'Connell K, Qiu Q, Riggle AJ, Shoultz TH, Maine RG, Arbabi S, O'Keefe GE, Cuschieri J, Maier RV, Robinson BRH| | View in PubMed
  50. Effect of Standardized Handoff Curriculum on Improved Clinician Preparedness in the Intensive Care Unit: A Stepped-Wedge Cluster Randomized Clinical Trial.
    Parent B, LaGrone LN, Albirair MT, Serina PT, Keller JM, Cuschieri J, Addison EJ, Choe L, Delossantos GB, Gaskill CE, Moon SD, MacDonald JT, Stolzberg MJ, Van Eaton EG, Zech JM, Kritek PA| | View in PubMed
  51. Fellowship training in extracorporeal life support: Characterization and educational needs assessment.
    Cook MR, Badulak J, Çoruh B, Kiraly LN, Zonies D, Cuschieri J, Bulger EM| | View in PubMed
  52. Short-Course Antimicrobial Therapy Does Not Increase Treatment Failure Rate in Patients with Intra-Abdominal Infection Involving Fungal Organisms.
    Elwood NR, Guidry CA, Duane TM, Cuschieri J, Cook CH, O'Neill PJ, Askari R, Napolitano LM, Namias N, Dellinger EP, Watson CM, Banton KL, Blake DP, Hassinger TE, Sawyer RG| | View in PubMed
  53. A cohort study of blunt cerebrovascular injury screening in children: Are they just little adults?
    Cook MR, Witt CE, Bonow RH, Bulger EM, Linnau KF, Arbabi S, Robinson BRH, Cuschieri J| | View in PubMed
  54. The Epidemiology of Chronic Critical Illness After Severe Traumatic Injury at Two Level-One Trauma Centers.
    Mira JC, Cuschieri J, Ozrazgat-Baslanti T, Wang Z, Ghita GL, Loftus TJ, Stortz JA, Raymond SL, Lanz JD, Hennessy LV, Brumback B, Efron PA, Baker HV, Moore FA, Maier RV, Moldawer LL, Brakenridge SC| | View in PubMed
  55. Novel Method Suggests Global Superiority of Short-Duration Antibiotics for Intra-abdominal Infections.
    Celestin AR, Odom SR, Angelidou K, Evans SR, Coimbra R, Guidry CA, Cuschieri J, Banton KL, O'Neill PJ, Askari R, Namias N, Duane TM, Claridge JA, Dellinger EP, Sawyer RA, Cook CH| | View in PubMed
  56. Does Isolation of Enterococcus Affect Outcomes in Intra-Abdominal Infections?
    Sanders JM, Tessier JM, Sawyer R, Dellinger EP, Miller PR, Namias N, West MA, Cook CH, O'Neill PJ, Napolitano L, Rattan R, Cuschieri J, Claridge JA, Guidry CA, Askari R, Banton K, Rotstein O, Moore BJ, Duane TM| | View in PubMed
  57. Transcranial Doppler Microemboli Monitoring for Stroke Risk Stratification in Blunt Cerebrovascular Injury.
    Bonow RH, Witt CE, Mosher BP, Mossa-Basha M, Vavilala MS, Rivara FP, Cuschieri J, Arbabi S, Chesnut RM| | View in PubMed
  58. Effect of Ganciclovir on IL-6 Levels Among Cytomegalovirus-Seropositive Adults With Critical Illness: A Randomized Clinical Trial.
    Limaye AP, Stapleton RD, Peng L, Gunn SR, Kimball LE, Hyzy R, Exline MC, Files DC, Morris PE, Frankel SK, Mikkelsen ME, Hite D, Enfield KB, Steingrub J, O'Brien J, Parsons PE, Cuschieri J, Wunderink RG, Hotchkin DL, Chen YQ, Rubenfeld GD, Boeckh M| | View in PubMed
  59. Validation of a Geriatric Trauma Prognosis Calculator: A P.A.L.Li.A.T.E. Consortium Study.
    Cook AC, Joseph B, Mohler MJ, Inaba K, Bruns BR, Nakonezny PA, Kerby JD, Brasel KJ, Wolf SE, Cuschieri J, Paulk ME, Rhodes RL, Brakenridge SC, Ekeh AP, Phelan HA| | View in PubMed
  60. A comparison of prognosis calculators for geriatric trauma: A Prognostic Assessment of Life and Limitations After Trauma in the Elderly consortium study.
    Madni TD, Ekeh AP, Brakenridge SC, Brasel KJ, Joseph B, Inaba K, Bruns BR, Kerby JD, Cuschieri J, Mohler MJ, Nakonezny PA, Clark A, Imran J, Wolf SE, Paulk ME, Rhodes RL, Phelan HA| | View in PubMed
  61. Longer-Duration Antimicrobial Therapy Does Not Prevent Treatment Failure in High-Risk Patients with Complicated Intra-Abdominal Infections.
    Hassinger TE, Guidry CA, Rotstein OD, Duane TM, Evans HL, Cook CH, O'Neill PJ, Mazuski JE, Askari R, Napolitano LM, Namias N, Miller PR, Dellinger EP, Coimbra R, Cocanour CS, Banton KL, Cuschieri J, Popovsky K, Sawyer RG| | View in PubMed
  62. Age and Its Impact on Outcomes with Intra-Abdominal Infection.
    Farmer D, Tessier JM, Sanders JM, Sawyer RG, Rotstein OD, Dellinger EP, Lipsett PA, Cuschieri J, Miller P, Cook CH, Guidry CA, Askari R, Moore BJ, Duane TM| | View in PubMed
  63. Preventing hospital-acquired venous thromboembolism: Improving patient safety with interdisciplinary teamwork, quality improvement analytics, and data transparency.
    Schleyer AM, Robinson E, Dumitru R, Taylor M, Hayes K, Pergamit R, Beingessner DM, Zaros MC, Cuschieri J| | View in PubMed
  64. Acute Rehabilitation after Trauma: Does it Really Matter?
    Nehra D, Nixon ZA, Lengenfelder C, Bulger EM, Cuschieri J, Maier RV, Arbabi S| | View in PubMed
  65. Patients with Risk Factors for Complications Do Not Require Longer Antimicrobial Therapy for Complicated Intra-Abdominal Infection.
    Rattan R, Allen CJ, Sawyer RG, Mazuski J, Duane TM, Askari R, Banton KL, Claridge JA, Coimbra R, Cuschieri J, Dellinger EP, Evans HL, Guidry CA, Miller PR, O'Neill PJ, Rotstein OD, West MA, Popovsky K, Namias N| | View in PubMed
  66. Sex-based differences in the genomic response, innate immunity, organ dysfunction, and clinical outcomes after severe blunt traumatic injury and hemorrhagic shock.
    Lopez MC, Efron PA, Ozrazgat-Baslanti T, Zhang J, Cuschieri J, Maier RV, Minei JP, Baker HV, Moore FA, Moldawer LL, Brakenridge SC| | View in PubMed
  67. Inclusion of Vancomycin as Part of Broad-Spectrum Coverage Does Not Improve Outcomes in Patients with Intra-Abdominal Infections: A Post Hoc Analysis.
    Sanders JM, Tessier JM, Sawyer RG, Lipsett PA, Miller PR, Namias N, O'Neill PJ, Dellinger EP, Coimbra R, Guidry CA, Cuschieri J, Banton KL, Cook CH, Moore BJ, Duane TM| | View in PubMed
  68. Surgical Management of Clostridium difficile Infection: The Role of Colectomy.
    Delano MJ, Cuschieri J| | View in PubMed
  69. Multicenter external validation of the Geriatric Trauma Outcome Score: A study by the Prognostic Assessment of Life and Limitations After Trauma in the Elderly (PALLIATE) consortium.
    Cook AC, Joseph B, Inaba K, Nakonezny PA, Bruns BR, Kerby JD, Brasel KJ, Wolf SE, Cuschieri J, Paulk ME, Rhodes RL, Brakenridge SC, Phelan HA| | View in PubMed
  70. Patients with Complicated Intra-Abdominal Infection Presenting with Sepsis Do Not Require Longer Duration of Antimicrobial Therapy.
    Rattan R, Allen CJ, Sawyer RG, Askari R, Banton KL, Claridge JA, Cocanour CS, Coimbra R, Cook CH, Cuschieri J, Dellinger EP, Duane TM, Evans HL, Lipsett PA, Mazuski JE, Miller PR, O'Neill PJ, Rotstein OD, Namias N| | View in PubMed
  71. The Role of Lipopolysaccharide Structure in Monocyte Activation and Cytokine Secretion.
    Plevin RE, Knoll M, McKay M, Arbabi S, Cuschieri J| | View in PubMed
  72. Pediatric solid organ injury operative interventions and outcomes at Harborview Medical Center, before and after introduction of a solid organ injury pathway for pediatrics.
    Dervan LA, King MA, Cuschieri J, Rivara FP, Weiss NS| | View in PubMed
  73. Prehospital Resuscitation of Traumatic Hemorrhagic Shock with Hypertonic Solutions Worsens Hypocoagulation and Hyperfibrinolysis.
    Delano MJ, Rizoli SB, Rhind SG, Cuschieri J, Junger W, Baker AJ, Dubick MA, Hoyt DB, Bulger EM| | View in PubMed
  74. Trial of short-course antimicrobial therapy for intraabdominal infection.
    Sawyer RG, Claridge JA, Nathens AB, Rotstein OD, Duane TM, Evans HL, Cook CH, O'Neill PJ, Mazuski JE, Askari R, Wilson MA, Napolitano LM, Namias N, Miller PR, Dellinger EP, Watson CM, Coimbra R, Dent DL, Lowry SF, Cocanour CS, West MA, Banton KL, Cheadle WG, Lipsett PA, Guidry CA, Popovsky K, STOP-IT Trial Investigators| | View in PubMed
  75. Pretrauma center red blood cell transfusion is associated with reduced mortality and coagulopathy in severely injured patients with blunt trauma.
    Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL, Inflammation and the Host Response to Injury Investigators| | View in PubMed
  76. Morbidity and survival probability in burn patients in modern burn care.
    Jeschke MG, Pinto R, Kraft R, Nathens AB, Finnerty CC, Gamelli RL, Gibran NS, Klein MB, Arnoldo BD, Tompkins RG, Herndon DN, Inflammation and the Host Response to Injury Collaborative Research Program| | View in PubMed
  77. Advanced age is associated with worsened outcomes and a unique genomic response in severely injured patients with hemorrhagic shock.
    Vanzant EL, Hilton RE, Lopez CM, Zhang J, Ungaro RF, Gentile LF, Szpila BE, Maier RV, Cuschieri J, Bihorac A, Leeuwenburgh C, Moore FA, Baker HV, Moldawer LL, Brakenridge SC, Efron PA, Inflammation and Host Response to Injury Investigators| | View in PubMed
  78. Evolving beyond the vicious triad: Differential mediation of traumatic coagulopathy by injury, shock, and resuscitation.
    Kutcher ME, Howard BM, Sperry JL, Hubbard AE, Decker AL, Cuschieri J, Minei JP, Moore EE, Brownstein BH, Maier RV, Cohen MJ| | View in PubMed
  79. Prehospital use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a reduced incidence of trauma-induced coagulopathy.
    Neal MD, Brown JB, Moore EE, Cuschieri J, Maier RV, Minei JP, Billiar TR, Peitzman AB, Cohen MJ, Sperry JL, Inflammation and Host Response to Injury Investigators| | View in PubMed
  80. Pre-hospital aspiration is associated with increased pulmonary complications.
    Fawcett VJ, Warner KJ, Cuschieri J, Copass M, Grabinsky A, Kwok H, Rea T, Evans HL| | View in PubMed
  81. A better understanding of why murine models of trauma do not recapitulate the human syndrome.
    Gentile LF, Nacionales DC, Lopez MC, Vanzant E, Cuenca A, Cuenca AG, Ungaro R, Baslanti TO, McKinley BA, Bihorac A, Cuschieri J, Maier RV, Moore FA, Leeuwenburgh C, Baker HV, Moldawer LL, Efron PA| | View in PubMed
  82. Benchmarking outcomes in the critically injured burn patient.
    Klein MB, Goverman J, Hayden DL, Fagan SP, McDonald-Smith GP, Alexander AK, Gamelli RL, Gibran NS, Finnerty CC, Jeschke MG, Arnoldo B, Wispelwey B, Mindrinos MN, Xiao W, Honari SE, Mason PH, Schoenfeld DA, Herndon DN, Tompkins RG, Inflammation and Host Response to Injury, and Large-Scale Collaborative Research Program| | View in PubMed
  83. Delayed topical p38 MAPK inhibition attenuates full-thickness burn wound inflammatory signaling.
    Carter D, Warsen A, Mandell K, Cuschieri J, Maier RV, Arbabi S| | View in PubMed
  84. Differences in end-of-life care in the ICU across patients cared for by medicine, surgery, neurology, and neurosurgery physicians.
    Kross EK, Engelberg RA, Downey L, Cuschieri J, Hallman MR, Longstreth WT, Tirschwell DL, Curtis JR| | View in PubMed
  85. Determining a core curriculum in surgical infections for fellowship training in acute care surgery using the Delphi technique.
    May AK, Cuschieri J, Johnson JL, Duane TM, Cherry-Bukowiec JR, Rosengart MR| | View in PubMed
  86. Upper extremity deep vein thrombosis in hospitalized patients: a descriptive study.
    Schleyer AM, Jarman KM, Calver P, Cuschieri J, Robinson E, Goss JR| | View in PubMed
  87. Prehospital hypertonic saline resuscitation attenuates the activation and promotes apoptosis of neutrophils in patients with severe traumatic brain injury.
    Junger WG, Rhind SG, Rizoli SB, Cuschieri J, Baker AJ, Shek PN, Hoyt DB, Bulger EM| | View in PubMed
  88. Determination of burn patient outcome by large-scale quantitative discovery proteomics.
    Finnerty CC, Jeschke MG, Qian WJ, Kaushal A, Xiao W, Liu T, Gritsenko MA, Moore RJ, Camp DG, Moldawer LL, Elson C, Schoenfeld D, Gamelli R, Gibran N, Klein M, Arnoldo B, Remick D, Smith RD, Davis R, Tompkins RG, Herndon DN, Investigators of the Inflammation and the Host Response Glue Grant| | View in PubMed
  89. Trauma-associated human neutrophil alterations revealed by comparative proteomics profiling.
    Zhou JY, Krovvidi RK, Gao Y, Gao H, Petritis BO, De AK, Miller-Graziano CL, Bankey PE, Petyuk VA, Nicora CD, Clauss TR, Moore RJ, Shi T, Brown JN, Kaushal A, Xiao W, Davis RW, Maier RV, Tompkins RG, Qian WJ, Camp DG, Smith RD, Inflammation and the Host Response to Injury Large Scale Collaborative Research Program| | View in PubMed
  90. Comparing clinical predictors of deep venous thrombosis versus pulmonary embolus after severe injury: a new paradigm for posttraumatic venous thromboembolism?
    Brakenridge SC, Henley SS, Kashner TM, Golden RM, Paik DH, Phelan HA, Cohen MJ, Sperry JL, Moore EE, Minei JP, Maier RV, Cuschieri J, Inflammation and the Host Response to Injury Investigators| | View in PubMed
  91. Development of a genomic metric that can be rapidly used to predict clinical outcome in severely injured trauma patients.
    Cuenca AG, Gentile LF, Lopez MC, Ungaro R, Liu H, Xiao W, Seok J, Mindrinos MN, Ang D, Baslanti TO, Bihorac A, Efron PA, Cuschieri J, Warren HS, Tompkins RG, Maier RV, Baker HV, Moldawer LL, Inflammation and Host Response to Injury Collaborative Research Program| | View in PubMed
  92. Goal-directed resuscitation in the prehospital setting: a propensity-adjusted analysis.
    Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL, Inflammation and the Host Response to Injury Investigators| | View in PubMed
  93. Genomic responses in mouse models poorly mimic human inflammatory diseases.
    Seok J, Warren HS, Cuenca AG, Mindrinos MN, Baker HV, Xu W, Richards DR, McDonald-Smith GP, Gao H, Hennessy L, Finnerty CC, López CM, Honari S, Moore EE, Minei JP, Cuschieri J, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Jeschke MG, Klein MB, Gamelli RL, Gibran NS, Brownstein BH, Miller-Graziano C, Calvano SE, Mason PH, Cobb JP, Rahme LG, Lowry SF, Maier RV, Moldawer LL, Herndon DN, Davis RW, Xiao W, Tompkins RG, Inflammation and Host Response to Injury, Large Scale Collaborative Research Program| | View in PubMed
  94. Antiplatelet therapy is associated with decreased transfusion-associated risk of lung dysfunction, multiple organ failure, and mortality in trauma patients.
    Harr JN, Moore EE, Johnson J, Chin TL, Wohlauer MV, Maier R, Cuschieri J, Sperry J, Banerjee A, Silliman CC, Sauaia A| | View in PubMed
  95. Characterization of acute coagulopathy and sexual dimorphism after injury: females and coagulopathy just do not mix.
    Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL, Inflammation and the Host Response to Injury Investigators| | View in PubMed
  96. Who should we feed? Western Trauma Association multi-institutional study of enteral nutrition in the open abdomen after injury.
    Burlew CC, Moore EE, Cuschieri J, Jurkovich GJ, Codner P, Nirula R, Millar D, Cohen MJ, Kutcher ME, Haan J, MacNew HG, Ochsner G, Rowell SE, Truitt MS, Moore FO, Pieracci FM, Kaups KL, WTA Study Group| | View in PubMed
  97. Resuscitation of traumatic hemorrhagic shock patients with hypertonic saline-without dextran-inhibits neutrophil and endothelial cell activation.
    Junger WG, Rhind SG, Rizoli SB, Cuschieri J, Shiu MY, Baker AJ, Li L, Shek PN, Hoyt DB, Bulger EM| | View in PubMed
  98. Acute respiratory distress syndrome after trauma: development and validation of a predictive model.
    Watkins TR, Nathens AB, Cooke CR, Psaty BM, Maier RV, Cuschieri J, Rubenfeld GD| | View in PubMed
  99. Hypothermia in massive transfusion: have we been paying enough attention to it?
    Reynolds BR, Forsythe RM, Harbrecht BG, Cuschieri J, Minei JP, Maier RV, Moore EE, Billiar EE, Peitzman AB, Sperry JL, Inflammation and Host Response to Injury Investigators| | View in PubMed
  100. The role and value of surgical critical care, an essential component of Acute Care Surgery, in the Affordable Care Act: a report from the Critical Care Committee and Board of Managers of the American Association for the Surgery of Trauma.
    Frankel HL, Butler KL, Cuschieri J, Friese RS, Huynh T, Mohr AM, Schinco MA, Napolitano LM, Britt LD, Coimbra R, Croce MA, Davis JW, Jurkovich GJ, Moore EE, Morris JA, Peitzman AB, Pruitt BA, Rozycki GS, Scalea TM, Meredith JW| | View in PubMed
  101. Active surveillance cultures of methicillin-resistant Staphylococcus aureus as a tool to predict methicillin-resistant S. aureus ventilator-associated pneumonia.
    Chan JD, Dellit TH, Choudhuri JA, McNamara E, Melius EJ, Evans HL, Cuschieri J, Arbabi S, Lynch JB| | View in PubMed
  102. Benchmarking outcomes in the critically injured trauma patient and the effect of implementing standard operating procedures.
    Cuschieri J, Johnson JL, Sperry J, West MA, Moore EE, Minei JP, Bankey PE, Nathens AB, Cuenca AG, Efron PA, Hennessy L, Xiao W, Mindrinos MN, McDonald-Smith GP, Mason PH, Billiar TR, Schoenfeld DA, Warren HS, Cobb JP, Moldawer LL, Davis RW, Maier RV, Tompkins RG, Inflammation and Host Response to Injury, Large Scale Collaborative Research Program| | View in PubMed
  103. Ventilator-associated pneumonia rates at major trauma centers compared with a national benchmark: a multi-institutional study of the AAST.
    Michetti CP, Fakhry SM, Ferguson PL, Cook A, Moore FO, Gross R, AAST Ventilator-Associated Pneumonia Investigators| | View in PubMed
  104. Crystalloid to packed red blood cell transfusion ratio in the massively transfused patient: when a little goes a long way.
    Neal MD, Hoffman MK, Cuschieri J, Minei JP, Maier RV, Harbrecht BG, Billiar TR, Peitzman AB, Moore EE, Cohen MJ, Sperry JL| | View in PubMed
  105. The changing pattern and implications of multiple organ failure after blunt injury with hemorrhagic shock.
    Minei JP, Cuschieri J, Sperry J, Moore EE, West MA, Harbrecht BG, O'Keefe GE, Cohen MJ, Moldawer LL, Tompkins RG, Maier RV, Inflammation and the Host Response to Injury Collaborative Research Program| | View in PubMed
  106. Obese patients show a depressed cytokine profile following severe blunt injury.
    Winfield RD, Delano MJ, Cuenca AG, Cendan JC, Lottenberg L, Efron PA, Maier RV, Remick DG, Moldawer LL, Cuschieri J| | View in PubMed
  107. Ventilator-associated pneumonia: bacteremia and death after traumatic injury.
    O'Keefe GE, Caldwell E, Cuschieri J, Wurfel MM, Evans HL| | View in PubMed
  108. Changes in massive transfusion over time: an early shift in the right direction?
    Kautza BC, Cohen MJ, Cuschieri J, Minei JP, Brackenridge SC, Maier RV, Harbrecht BG, Moore EE, Billiar TR, Peitzman AB, Sperry JL, Inflammation and the Host Response to Injury Investigators| | View in PubMed
  109. A genomic storm in critically injured humans.
    Xiao W, Mindrinos MN, Seok J, Cuschieri J, Cuenca AG, Gao H, Hayden DL, Hennessy L, Moore EE, Minei JP, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Brownstein BH, Mason PH, Baker HV, Finnerty CC, Jeschke MG, López MC, Klein MB, Gamelli RL, Gibran NS, Arnoldo B, Xu W, Zhang Y, Calvano SE, McDonald-Smith GP, Schoenfeld DA, Storey JD, Cobb JP, Warren HS, Moldawer LL, Herndon DN, Lowry SF, Maier RV, Davis RW, Tompkins RG, Inflammation and Host Response to Injury Large-Scale Collaborative Research Program| | View in PubMed
  110. Increased neutrophil adenosine a3 receptor expression is associated with hemorrhagic shock and injury severity in trauma patients.
    Bulger EM, Tower CM, Warner KJ, Garland T, Cuschieri J, Rizoli S, Rhind S, Junger WG| | View in PubMed
  111. Pre-hospital intubation factors and pneumonia in trauma patients.
    Evans HL, Warner K, Bulger EM, Sharar SR, Maier RV, Cuschieri J| | View in PubMed
  112. Dissecting inflammatory complications in critically injured patients by within-patient gene expression changes: a longitudinal clinical genomics study.
    Desai KH, Tan CS, Leek JT, Maier RV, Tompkins RG, Storey JD, Inflammation and the Host Response to Injury Large-Scale Collaborative Research Program| | View in PubMed
  113. The Glue Grant experience: characterizing the post injury genomic response.
    Cuenca AG, Maier RV, Cuschieri J, Moore EE, Moldawer LL, Tompkins RG, Inflammation and Host Response to Injury, Large Scale Collaborative Research Program| | View in PubMed
  114. Early blood product and crystalloid volume resuscitation: risk association with multiple organ dysfunction after severe blunt traumatic injury.
    Brakenridge SC, Phelan HA, Henley SS, Golden RM, Kashner TM, Eastman AE, Sperry JL, Harbrecht BG, Moore EE, Cuschieri J, Maier RV, Minei JP, Inflammation and the Host Response to Injury Investigators| | View in PubMed
  115. Clinical outcomes of linezolid vs vancomycin in methicillin-resistant Staphylococcus aureus ventilator-associated pneumonia: retrospective analysis.
    Chan JD, Pham TN, Wong J, Hessel M, Cuschieri J, Neff M, Dellit TH| | View in PubMed
  116. Steroids after severe injury: many unanswered questions.
    Bulger EM, Cuschieri J| | View in PubMed
  117. Human transcriptome array for high-throughput clinical studies.
    Xu W, Seok J, Mindrinos MN, Schweitzer AC, Jiang H, Wilhelmy J, Clark TA, Kapur K, Xing Y, Faham M, Storey JD, Moldawer LL, Maier RV, Tompkins RG, Wong WH, Davis RW, Xiao W, Inflammation and Host Response to Injury Large-Scale Collaborative Research Program| | View in PubMed
  118. Body adipose content is independently associated with a higher risk of organ failure and nosocomial infection in the nonobese patient postinjury.
    Edmonds RD, Cuschieri J, Minei JP, Rosengart MR, Maier RV, Harbrecht BG, Billiar TR, Peitzman AB, Moore EE, Sperry JL, Inflammation the Host Response to Injury Investigators| | View in PubMed
  119. Sew it up! A Western Trauma Association multi-institutional study of enteric injury management in the postinjury open abdomen.
    Burlew CC, Moore EE, Cuschieri J, Jurkovich GJ, Codner P, Crowell K, Nirula R, Haan J, Rowell SE, Kato CM, MacNew H, Ochsner MG, Harrison PB, Fusco C, Sauaia A, Kaups KL, WTA Study Group| | View in PubMed
  120. The association between the transfusion of older blood and outcomes after trauma.
    Hassan M, Pham TN, Cuschieri J, Warner KJ, Nester T, Maier RV, Shalhub S, O'Keefe GE| | View in PubMed
  121. Identification and interpretation of longitudinal gene expression changes in trauma.
    Rajicic N, Cuschieri J, Finkelstein DM, Miller-Graziano CL, Hayden D, Moldawer LL, Moore E, O'Keefe G, Pelik K, Warren HS, Schoenfeld DA, Inflammation and the Host Response to Injury Large Scale Collaborative Research Program| | View in PubMed
  122. Timing of intubation and ventilator-associated pneumonia following injury.
    Evans HL, Zonies DH, Warner KJ, Bulger EM, Sharar SR, Maier RV, Cuschieri J| | View in PubMed
  123. Early elevation in random plasma IL-6 after severe injury is associated with development of organ failure.
    Cuschieri J, Bulger E, Schaeffer V, Sakr S, Nathens AB, Hennessy L, Minei J, Moore EE, O'Keefe G, Sperry J, Remick D, Tompkins R, Maier RV, Inflammation and the Host Response to Injury Collaborative Research Program| | View in PubMed
  124. Plasma proteome response to severe burn injury revealed by 18O-labeled "universal" reference-based quantitative proteomics.
    Qian WJ, Petritis BO, Kaushal A, Finnerty CC, Jeschke MG, Monroe ME, Moore RJ, Schepmoes AA, Xiao W, Moldawer LL, Davis RW, Tompkins RG, Herndon DN, Camp DG, Smith RD, Inflammation and the Host Response to Injury Large Scale Collaborative Research Program| | View in PubMed
  125. Clinical microfluidics for neutrophil genomics and proteomics.
    Kotz KT, Xiao W, Miller-Graziano C, Qian WJ, Russom A, Warner EA, Moldawer LL, De A, Bankey PE, Petritis BO, Camp DG, Rosenbach AE, Goverman J, Fagan SP, Brownstein BH, Irimia D, Xu W, Wilhelmy J, Mindrinos MN, Smith RD, Davis RW, Tompkins RG, Toner M, Inflammation and the Host Response to Injury Collaborative Research Program| | View in PubMed
  126. Role of the mTOR pathway in LPS-activated monocytes: influence of hypertonic saline.
    Schaeffer V, Arbabi S, Garcia IA, Knoll ML, Cuschieri J, Bulger EM, Maier RV| | View in PubMed
  127. Analysis of factorial time-course microarrays with application to a clinical study of burn injury.
    Zhou B, Xu W, Herndon D, Tompkins R, Davis R, Xiao W, Wong WH, Inflammation and Host Response to Injury Program, Toner M, Warren HS, Schoenfeld DA, Rahme L, McDonald-Smith GP, Hayden D, Mason P, Fagan S, Yu YM, Cobb JP, Remick DG, Mannick JA, Lederer JA, Gamelli RL, Silver GM, West MA, Shapiro MB, Smith R, Camp DG, Qian W, Storey J, Mindrinos M, Tibshirani R, Lowry S, Calvano S, Chaudry I, West MA, Cohen M, Moore EE, Johnson J, Moldawer LL, Baker HV, Efron PA, Balis UG, Billiar TR, Ochoa JB, Sperry JL, Miller-Graziano CL, De AK, Bankey PE, Finnerty CC, Jeschke MG, Minei JP, Arnoldo BD, Hunt JL, Horton J, Cobb JP, Brownstein B, Freeman B, Maier RV, Nathens AB, Cuschieri J, Gibran N, Klein M, O'Keefe G| | View in PubMed
  128. Effect of chlorhexidine whole-body bathing on hospital-acquired infections among trauma patients.
    Evans HL, Dellit TH, Chan J, Nathens AB, Maier RV, Cuschieri J| | View in PubMed
  129. Traditional resuscitative practices fail to resolve metabolic acidosis in morbidly obese patients after severe blunt trauma.
    Winfield RD, Delano MJ, Lottenberg L, Cendan JC, Moldawer LL, Maier RV, Cuschieri J| | View in PubMed
  130. Differences in outcome between obese and nonobese patients following severe blunt trauma are not consistent with an early inflammatory genomic response.
    Winfield RD, Delano MJ, Dixon DJ, Schierding WS, Cendan JC, Lottenberg L, Lopez MC, Baker HV, Cobb JP, Moldawer LL, Maier RV, Cuschieri J| | View in PubMed
  131. Oxidant alterations in CD16 expression are cytoskeletal induced.
    Cuschieri J, Sakr S, Bulger E, Knoll M, Arbabi S, Maier RV| | View in PubMed
  132. Validation of the riboleukogram to detect ventilator-associated pneumonia after severe injury.
    Cobb JP, Moore EE, Hayden DL, Minei JP, Cuschieri J, Yang J, Li Q, Lin N, Brownstein BH, Hennessy L, Mason PH, Schierding WS, Dixon DJ, Tompkins RG, Warren HS, Schoenfeld DA, Maier RV| | View in PubMed
  133. Analysis of the relationship between longitudinal gene expressions and ordered categorical event data.
    Rajicic N, Finkelstein DM, Schoenfeld DA, Inflammation and Host Response to Injury Research Program Investigators| | View in PubMed
  134. Fresh frozen plasma is independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome.
    Watson GA, Sperry JL, Rosengart MR, Minei JP, Harbrecht BG, Moore EE, Cuschieri J, Maier RV, Billiar TR, Peitzman AB, Inflammation and Host Response to Injury Investigators| | View in PubMed
  135. Inflammation and the host response to injury, a Large-Scale Collaborative Project: patient-oriented research core standard operating procedures for clinical care IX. Definitions for complications of clinical care of critically injured patients.
    Evans HL, Cuschieri J, Moore EE, Shapiro MB, Nathens AB, Johnson JL, Harbrecht BG, Minei JP, Bankey PE, Maier RV, West MA, Inflammation and Host Response to Injury Investigators| | View in PubMed
  136. Single-dose etomidate for rapid sequence intubation may impact outcome after severe injury.
    Warner KJ, Cuschieri J, Jurkovich GJ, Bulger EM| | View in PubMed
  137. Assessing statistical significance in microarray experiments using the distance between microarrays.
    Hayden D, Lazar P, Schoenfeld D, Inflammation and the Host Response to Injury Investigators| | View in PubMed
  138. A genomic score prognostic of outcome in trauma patients.
    Warren HS, Elson CM, Hayden DL, Schoenfeld DA, Cobb JP, Maier RV, Moldawer LL, Moore EE, Harbrecht BG, Pelak K, Cuschieri J, Herndon DN, Jeschke MG, Finnerty CC, Brownstein BH, Hennessy L, Mason PH, Tompkins RG, Inflammation and Host Response to Injury Large Scale Collaborative Research Program| | View in PubMed
  139. Characterization of persistent hyperglycemia: what does it mean postinjury?
    Sperry JL, Frankel HL, Nathens AB, O'keefe GE, Cuschieri J, Moore EE, Maier RV, Minei JP, Inflammation and the Host Response to Injury Investigators| | View in PubMed
  140. Assessment of functional limitation after necrotizing soft tissue infection.
    Pham TN, Moore ML, Costa BA, Cuschieri J, Klein MB| | View in PubMed
  141. The utility of early end-tidal capnography in monitoring ventilation status after severe injury.
    Warner KJ, Cuschieri J, Garland B, Carlbom D, Baker D, Copass MK, Jurkovich GJ, Bulger EM| | View in PubMed
  142. The evolution of the diagnostic work-up for stab wounds to the back and flank.
    Pham TN, Heinberg E, Cuschieri J, Bulger EM, O'Keefe GE, Gross JA, Jurkovich GJ| | View in PubMed
  143. Inflammation and the host response to injury, a large-scale collaborative project: patient-oriented research core--standard operating procedures for clinical care VII--Guidelines for antibiotic administration in severely injured patients.
    West MA, Moore EE, Shapiro MB, Nathens AB, Cuschieri J, Johnson JL, Harbrecht BG, Minei JP, Bankey PE, Maier RV, Inflammation and the Host Response to Injury Collaborative Research Program| | View in PubMed
  144. Inflammation and the host response to injury, a large-scale collaborative project: patient-oriented research core--standard operating procedures for clinical care VIII--Nutritional support of the trauma patient.
    O'Keefe GE, Shelton M, Cuschieri J, Moore EE, Lowry SF, Harbrecht BG, Maier RV, Inflammation and the Host Response to Injury Collaborative Research Program| | View in PubMed
  145. Necrotizing soft tissue infection.
    Cuschieri J| | View in PubMed
  146. An FFP:PRBC transfusion ratio >/=1:1.5 is associated with a lower risk of mortality after massive transfusion.
    Sperry JL, Ochoa JB, Gunn SR, Alarcon LH, Minei JP, Cuschieri J, Rosengart MR, Maier RV, Billiar TR, Peitzman AB, Moore EE, Inflammation the Host Response to Injury Investigators| | View in PubMed
  147. Inflammation and the host response to injury a large-scale collaborative project: patient-oriented research core standard operating procedure for clinical care X. Guidelines for venous thromboembolism prophylaxis in the trauma patient.
    Cuschieri J, Freeman B, O'Keefe G, Harbrecht BG, Bankey P, Johnson JL, Minei JP, Sperry J, West M, Nathens A, Moore EE, Maier RV, Inflammation and the Host Response to Injury Collaborative Research Program| | View in PubMed
  148. Negative appendectomy and imaging accuracy in the Washington State Surgical Care and Outcomes Assessment Program.
    SCOAP Collaborative, Cuschieri J, Florence M, Flum DR, Jurkovich GJ, Lin P, Steele SR, Symons RG, Thirlby R| | View in PubMed
  149. Survey of surgical infections currently known (SOSICK): a multicenter examination of antimicrobial use from the surgical infection society scientific studies committee.
    Namias N, Meizoso JP, Livingston DH, SOSICK Investigators Group| | View in PubMed
  150. Effect of immediate enteral feeding on trauma patients with an open abdomen: protection from nosocomial infections.
    Dissanaike S, Pham T, Shalhub S, Warner K, Hennessy L, Moore EE, Maier RV, O'Keefe GE, Cuschieri J| | View in PubMed
  151. Early supplemental parenteral nutrition is associated with increased infectious complications in critically ill trauma patients.
    Sena MJ, Utter GH, Cuschieri J, Maier RV, Tompkins RG, Harbrecht BG, Moore EE, O'Keefe GE| | View in PubMed
  152. Male gender is associated with excessive IL-6 expression following severe injury.
    Sperry JL, Friese RS, Frankel HL, West MA, Cuschieri J, Moore EE, Harbrecht BG, Peitzman AB, Billiar TR, Maier RV, Remick DG, Minei JP, Inflammation and the Host Response to Injury Investigators| | View in PubMed
  153. Emergency department ventilation effects outcome in severe traumatic brain injury.
    Warner KJ, Cuschieri J, Copass MK, Jurkovich GJ, Bulger EM| | View in PubMed
  154. Insulin regulates macrophage activation through activin A.
    Cuschieri J, Bulger E, Grinsell R, Garcia I, Maier RV| | View in PubMed
  155. Mechanistic analysis of macrophage response to IRAK-1 gene knockdown by a smart polymer-antisense oligonucleotide therapeutic.
    Johns RE, El-Sayed ME, Bulmus V, Cuschieri J, Maier R, Hoffman AS, Stayton PS| | View in PubMed
  156. Inflammation and the host response to injury, a large-scale collaborative project: patient-oriented research core-standard operating procedures for clinical care: VI. Blood glucose control in the critically ill trauma patient.
    Harbrecht BG, Minei JP, Shapiro MB, Nathens AB, Moore EE, West MA, Bankey PE, Cuschieri J, Johnson JL, Maier RV, Inflammation and the Host Response to Injury Scale Collaborative Research Project| | View in PubMed
  157. Oxidative stress, lipid rafts, and macrophage reprogramming.
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  158. The impact of prehospital ventilation on outcome after severe traumatic brain injury.
    Warner KJ, Cuschieri J, Copass MK, Jurkovich GJ, Bulger EM| | View in PubMed
  159. The priming effect of C5a on monocytes is predominantly mediated by the p38 MAPK pathway.
    Schaeffer V, Cuschieri J, Garcia I, Knoll M, Billgren J, Jelacic S, Bulger E, Maier R| | View in PubMed
  160. Hypertonic resuscitation modulates the inflammatory response in patients with traumatic hemorrhagic shock.
    Bulger EM, Cuschieri J, Warner K, Maier RV| | View in PubMed
  161. The practice of venous thromboembolism prophylaxis in the major trauma patient.
    Nathens AB, McMurray MK, Cuschieri J, Durr EA, Moore EE, Bankey PE, Freeman B, Harbrecht BG, Johnson JL, Minei JP, McKinley BA, Moore FA, Shapiro MB, West MA, Tompkins RG, Maier RV| | View in PubMed
  162. Acid sphingomyelinase is required for lipid Raft TLR4 complex formation.
    Cuschieri J, Bulger E, Billgrin J, Garcia I, Maier RV| | View in PubMed
  163. Vitamin E inhibits endotoxin-mediated transport of phosphatases to lipid rafts.
    Cuschieri J, Bulger E, Biligren J, Garcia I, Maier RV| | View in PubMed
  164. Surgical management of acute necrotizing lung infections.
    Reimel BA, Krishnadasen B, Cuschieri J, Klein MB, Gross J, Karmy-Jones R| | View in PubMed
  165. Endotoxin tolerance attenuates LPS-induced TLR4 mobilization to lipid rafts: a condition reversed by PKC activation.
    Cuschieri J, Billigren J, Maier RV| | View in PubMed
  166. Phosphatidylcholine-specific phospholipase C (PC-PLC) is required for LPS-mediated macrophage activation through CD14.
    Cuschieri J, Billgren J, Maier RV| | View in PubMed
  167. The modeling of the radiation and response green's function of a fluid-loaded cylindrical shell with an external compliant layer.
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  168. Mitogen-activated protein kinase (MAPK).
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  169. Accidental self-inflicted nail gun injury to the heart
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  170. Oxidative-induced calcium mobilization is dependent on annexin VI release from lipid rafts.
    Cuschieri J, Bulger E, Garcia I, Maier RV| | View in PubMed
  171. Central venous-arterial carbon dioxide difference as an indicator of cardiac index.
    Cuschieri J, Rivers EP, Donnino MW, Katilius M, Jacobsen G, Nguyen HB, Pamukov N, Horst HM| | View in PubMed
  172. Calcium/calmodulin-dependent kinase II is required for platelet-activating factor priming.
    Cuschieri J, Bulger E, Garcia I, Jelacic S, Maier RV| | View in PubMed
  173. The role of repeat angiography in the management of pelvic fractures.
    Shapiro M, McDonald AA, Knight D, Johannigman JA, Cuschieri J| | View in PubMed
  174. PKC-zeta is essential for endotoxin-induced macrophage activation.
    Cuschieri J, Umanskiy K, Solomkin J| | View in PubMed
  175. Implications of lipid raft disintegration: enhanced anti-inflammatory macrophage phenotype.
    Cuschieri J| | View in PubMed
  176. Implications of proteasome inhibition: an enhanced macrophage phenotype.
    Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV| | View in PubMed
  177. Modulation of macrophage responsiveness to lipopolysaccharide by IRAK-1 manipulation.
    Cuschieri J, Bulmus V, Gourlay D, Garcia I, Hoffman A, Stayton P, Maier RV| | View in PubMed
  178. Modulation of endotoxin-induced endothelial function by calcium/calmodulin-dependent protein kinase.
    Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV| | View in PubMed
  179. NADPH oxidase activation in fibronectin adherent human neutrophils: A potential role for beta1 integrin ligation.
    Umanskiy K, Robinson C, Cave C, Williams MA, Lentsch AB, Cuschieri J, Solomkin JS| | View in PubMed
  180. Platelet-activating factor acetylhydrolase inhibits alveolar macrophage activation in vivo.
    Bulger EM, Gourlay D, Cuschieri J, Jelacic S, Staudenmeyer K, Garcia I, Maier RV| | View in PubMed
  181. Endotoxin-induced endothelial cell proinflammatory phenotypic differentiation requires stress fiber polymerization.
    Cuschleri J, Gourlay D, Garcia I, Jelacic S, Maier RV| | View in PubMed
  182. Modulation of endotoxin-induced endothelial activity by microtubule depolymerization.
    Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV| | View in PubMed
  183. Platelet-activating factor priming of inflammatory cell activity requires cellular adherence.
    Cuschieri J, Gourlay D, Bulger E, Garcia I, Jelacic S, Maier RV| | View in PubMed
  184. Slow channel calcium inhibition blocks proinflammatory gene signaling and reduces macrophage responsiveness.
    Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV| | View in PubMed
  185. Hypertonic preconditioning inhibits macrophage responsiveness to endotoxin.
    Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV| | View in PubMed
  186. Role of bronchoscopy in massive hemoptysis.
    Karmy-Jones R, Cuschieri J, Vallières E| | View in PubMed
  187. Clearing the cervical spine in victims of blunt assault to the head and neck: what is necessary?
    Patton JH, Kralovich KA, Cuschieri J, Gasparri M| | View in PubMed
  188. Anterior mediastinal abscess after closed sternal fracture.
    Cuschieri J, Kralovich KA, Patton JH, Horst HM, Obeid FN, Karmy-Jones R| | View in PubMed