Biography
Chris E. Freise, M.D. received his medical degree from the University of Minnesota where he also did his internship and residency in General Surgery. He later completed a transplantation fellowship at UCSF.
He is a member of numerous professional organizations including The Transplantation Society, the International Pancreas and Islet Transplant Association, the Transplant Infectious Disease Society, the American Hepato-Pancreato-Billiary Association and the Society of University Surgeons. In addition, he recently served as the Medical Director for California Transplant Donor Network. He is also the Associate Counselor for UNOS Region 5, and a member of the UNOS Membership and Professional Standards Committee.
Dr. Freise has authored more than eighty (80) in peer-reviewed publications and five (5) book chapters. He is an accomplished researcher and clinical educator. Dr. Freise is also a frequent invited lecturer to national and international and conferences in the field.
Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
University of California | Diversity, Equity, and Inclusion Champion Training | 2019 | |
University of California, San Francisco | Transplant Fellowship | School of Medicine | 1995 |
University of California, San Francisco | Post-Doc Fellow/Scholar | School of Medicine | 1991 |
University of Minnesota | M.D. | School of Medicine | 1986 |
Board Certifications
- American Board of Surgery, 1995
Clinical Expertise
Bile Duct Injuries
Bile Duct Strictures
Cholangiocarcinoma (Bile Duct Cancer)
Choledochal Cyst Disease
Dialysis Access
Expanded Criteria Donor Kidney Transplantation
Fulminant Hepatic Failure
Hepatitis B
Hepatitis C
Hepatocellular Carcinoma (Liver Cancer)
Intestinal Transplantation and Rehabilitation
Kidney and LIver Transplantation in HIV Patients
Kidney Auto-transplantation
Kidney Transplantation
Laparoscopic Donor Nephrectomy
Laparoscopic Kidney and Liver Surgery
Liver Transplantation
Living Donor Kidney Transplantation
Living Donor Liver Transplantation
Pancreas Transplantation
Pediatric Kidney Transplantation
Pediatric Liver Transplantation
Polycystic Kidney Disease
Polycystic Liver Disease
Portal Hypertension
Surgical Shunts
In the News
Grants and Funding
- Living Donor Liver Transplant :Short & Long-Term Impact on Donors and Recipients | NIH | 2002-09-01 - 2015-08-31 | Role: Principal Investigator
Research Narrative
Dr. Friese's basic science research focuses on the delivery of immunosuppressive agents to organ allografts, ischemia reperfusion injury, and methods to improve organ function in deceased donors. His clinical research includes a multicenter trial investigating donor and recipient outcomes following living donor liver transplantation.
Research Interests
Delivery of Immunosuppressive Agents to Organ Allografts
Ischemia Reperfusion Injury
Improvement Organ Function in Deceased Donors
Publications
- Ureteral avulsion after ureteroscopy treated with renal auto-transplantation.| | View in PubMed
- Peritoneal Dialysis Catheter Complications after Insertion by Surgeons, Radiologists, or Nephrologists.| | View in PubMed
- DCD liver transplant in patients with a MELD over 35.| | View in PubMed
- Advantages and Limitations of Clinical Scores for Donation After Circulatory Death Liver Transplantation.| | View in PubMed
- Motivations and outcomes of compatible living donor-recipient pairs in paired exchange.| | View in PubMed
- Retransplantation After Living Donor Liver Transplantation: Data from the Adult to Adult Living Donor Liver Transplantation Study.| | View in PubMed
- Biliary obstruction following ureteral revision of a transplanted kidney.| | View in PubMed
- Setting rules for the sandbox: A response to "Successfully sharing the sandbox: A perspective on combined DCD liver and heart donor procurement".| | View in PubMed
- Treatment of immunocompromised COVID-19 patients with convalescent plasma.| | View in PubMed
- Opioid use prior to liver transplant is associated with increased risk of death after transplant.| | View in PubMed
- Molecular Insights in Transmission of Cancer From an Organ Donor to Four Transplant Recipients.| | View in PubMed
- Contemporary Management of Hepatic Cyst Disease: Techniques and Outcomes at a Tertiary Hepatobiliary Center.| | View in PubMed
- Impact of Sarcopenia on Simultaneous Pancreas and Kidney Transplantation Outcomes: A Retrospective Observational Cohort Study.| | View in PubMed
- Inferior Long-Term Graft Survival of Suboptimal Kidneys After Living Donor Kidney Transplantation.| | View in PubMed
- Rapid Modification of Workflows and Fellow Staffing at a Single Transplant Center to Address the COVID-19 Crisis.| | View in PubMed
- Living Donor Liver Transplant for Alcoholic Liver Disease: Data from the Adult-to-adult Living Donor Liver Transplantation Study.| | View in PubMed
- Bi-organ paired exchange-Sentinel case of a liver-kidney swap.| | View in PubMed
- Fatigue, Pain, and Other Physical Symptoms of Living Liver Donors in the Adult-to-Adult Living Donor Liver Transplantation Cohort Study.| | View in PubMed
- Splenic Vein Thrombosis Following Pancreas Transplantation: Identification of Factors That Support Conservative Management.| | View in PubMed
- Collagen XIV and a related recombinant fragment protect human vascular smooth muscle cells from calcium-/phosphate-induced osteochondrocytic transdifferentiation.| | View in PubMed
- Pancreas-After-Islet Transplantation in Nonuremic Type 1 Diabetes: A Strategy for Restoring Durable Insulin Independence.| | View in PubMed
- Vascular complication rates in living donor liver transplantation: How low can we go?| | View in PubMed
- A Single Perioperative Injection of Dexamethasone Decreases Nausea, Vomiting, and Pain after Laparoscopic Donor Nephrectomy.| | View in PubMed
- De novo thyroid cancer following solid organ transplantation-A 25-year experience at a high-volume institution with a review of the literature.| | View in PubMed
- Social and Financial Outcomes of Living Liver Donation: A Prospective Investigation Within the Adult-to-Adult Living Donor Liver Transplantation Cohort Study 2 (A2ALL-2).| | View in PubMed
- Early Postoperative Pain and its Predictors in the Adult to Adult Living Donor Liver Transplantation Cohort Study.| | View in PubMed
- Impact of Graft Selection on Donor and Recipient Outcomes After Living Donor Liver Transplantation.| | View in PubMed
- Psychosocial Outcomes 3 to 10 Years After Donation in the Adult to Adult Living Donor Liver Transplantation Cohort Study.| | View in PubMed
- Complications and Their Resolution in Recipients of Deceased and Living Donor Liver Transplants: Findings From the A2ALL Cohort Study.| | View in PubMed
- Defining long-term outcomes with living donor liver transplantation in North America.| | View in PubMed
- Laparoscopic Nephrectomy with Autotransplantation: Safety, Efficacy and Long-Term Durability.| | View in PubMed
- Liver regeneration after living donor transplantation: adult-to-adult living donor liver transplantation cohort study.| | View in PubMed
- Long-term quality of life after liver donation in the adult to adult living donor liver transplantation cohort study (A2ALL).| | View in PubMed
- Restricting liver transplant recipients to younger donors does not increase the wait-list time or the dropout rate: the hepatitis C experience.| | View in PubMed
- Emesis following laparoscopic left donor nephrectomy.| | View in PubMed
- Ex vivo split-liver transplantation: the true right/left split.| | View in PubMed
- Outcomes of living and deceased donor liver transplant recipients with hepatocellular carcinoma: results of the A2ALL cohort.| | View in PubMed
- Risk factors for liver transplant waitlist dropout in patients with hepatocellular carcinoma.| | View in PubMed
- Complications of living donor hepatic lobectomy--a comprehensive report.| | View in PubMed
- Use of living donor liver transplantation varies with the availability of deceased donor liver transplantation.| | View in PubMed
- Outcomes with split liver transplantation in 106 recipients: the University of California, San Francisco, experience from 1993 to 2010.| | View in PubMed
- Liver transplantation for giant hepatic angiomyolipoma.| | View in PubMed
- Experience with laparoscopic donor nephrectomy among more than 1000 cases: low complication rates, despite more challenging cases.| | View in PubMed
- Ten-year retrospective analysis of incisional herniorrhaphy following renal transplantation.| | View in PubMed
- Fibrin plug.| | View in PubMed
- Outcomes of surgical repair of bile leaks and strictures after adult-to-adult living donor liver transplant.| | View in PubMed
- Comparison of biliary complications in adult living-donor liver transplants performed at two busy transplant centers.| | View in PubMed
- Inguinal herniation of a transplant ureter.| | View in PubMed
- Emergent orthotopic liver transplantation for hemorrhage from a giant cavernous hepatic hemangioma: case report and review.| | View in PubMed
- Left lobe adult-to-adult living donor liver transplantation: small grafts and hemiportocaval shunts in the prevention of small-for-size syndrome.| | View in PubMed
- Open incisional hernia repair at an academic tertiary care medical center.| | View in PubMed
- Prostate cancer screening and treatment in the transplant population: current status and recommendations.| | View in PubMed
- Genes involved in viral carcinogenesis and tumor initiation in hepatitis C virus-induced hepatocellular carcinoma.| | View in PubMed
- Recipient morbidity after living and deceased donor liver transplantation: findings from the A2ALL Retrospective Cohort Study.| | View in PubMed
- Excellent outcome following down-staging of hepatocellular carcinoma prior to liver transplantation: an intention-to-treat analysis.| | View in PubMed
- Outcomes of living donor liver transplantation for acute liver failure: the adult-to-adult living donor liver transplantation cohort study.| | View in PubMed
- Donor morbidity after living donation for liver transplantation.| | View in PubMed
- Organ donation and utilization in the United States, 1997-2006.| | View in PubMed
- HIV-infected liver and kidney transplant recipients: 1- and 3-year outcomes.| | View in PubMed
- Long-term outcomes and late complications of laparoscopic nephrectomy with renal autotransplantation.| | View in PubMed
- Catheter-directed therapy for DVT after pancreas transplantation.| | View in PubMed
- Laparoscopic nephrectomy, ex vivo partial nephrectomy followed by allograft renal transplantation.| | View in PubMed
- Improvement in survival associated with adult-to-adult living donor liver transplantation.| | View in PubMed
- Hepatocellular carcinoma recurrence and death following living and deceased donor liver transplantation.| | View in PubMed
- Glutamine donor pretreatment in rat kidney transplants with severe preservation reperfusion injury.| | View in PubMed
- Predicting biliary complications in right lobe liver transplant recipients according to distance between donor's bile duct and corresponding hepatic artery.| | View in PubMed
- Effect of mycophenolate mofetil on rat kidney grafts with prolonged cold preservation.| | View in PubMed
- A prospective study on downstaging of hepatocellular carcinoma prior to liver transplantation.| | View in PubMed
- End stage polycystic kidney disease: indications and timing of native nephrectomy relative to kidney transplantation.| | View in PubMed
- More than 500 consecutive laparoscopic donor nephrectomies without conversion or repeated surgery.| | View in PubMed
- Outcomes of 385 adult-to-adult living donor liver transplant recipients: a report from the A2ALL Consortium.| | View in PubMed
- Laparoscopic procurement of kidneys with multiple renal arteries is associated with increased ureteral complications in the recipient.| | View in PubMed
- H-NMR-based metabolic signatures of mild and severe ischemia/reperfusion injury in rat kidney transplants.| | View in PubMed
- BKV in simultaneous pancreas-kidney transplant recipients: a leading cause of renal graft loss in first 2 years post-transplant.| | View in PubMed
- Laparoscopic right donor nephrectomy: a large single-center experience.| | View in PubMed
- Increased rejection in living unrelated versus living related kidney transplants does not affect short-term function and survival.| | View in PubMed
- Laparoscopic nephrectomy, ex vivo excision and autotransplantation for complex renal tumors.| | View in PubMed
- Early graft function after living donor kidney transplantation predicts rejection but not outcomes.| | View in PubMed
- Laparoscopic-assisted upper pole ureterocalicostomy using renal inversion and autotransplantation.| | View in PubMed
- Experience with steroid-free maintenance immunosuppression in simultaneous pancreas-kidney transplantation.| | View in PubMed
- Polyomavirus-associated nephropathy in simultaneous kidney-pancreas transplant recipients: a single-center experience.| | View in PubMed
- Technique, indications and outcomes of pure laparoscopic right donor nephrectomy.| | View in PubMed
- Pure laparoscopic right donor nephrectomy: step-by-step approach.| | View in PubMed
- Influence of donor pretreatment with N-acetylcysteine on ischemia/reperfusion injury in rat kidney grafts.| | View in PubMed
- Laparoscopic donor nephrectomy for pediatric recipients: outcomes analysis.| | View in PubMed
- Sirolimus delays recovery of rat kidney transplants after ischemia-reperfusion injury.| | View in PubMed
- Excellent short-term results with steroid-free maintenance immunosuppression in low-risk simultaneous pancreas-kidney transplantation.| | View in PubMed
- Laparoscopic radical nephrectomy for suspected renal cell carcinoma in dialysis-dependent patients.| | View in PubMed
- Kidney and liver transplantation in human immunodeficiency virus-infected patients: a pilot safety and efficacy study.| | View in PubMed
- Management of lymphoceles after renal transplantation: laparoscopic versus open drainage.| | View in PubMed
- Sclerosing peritonitis.| | View in PubMed
- Expanded experience with laparoscopic nephrectomy and autotransplantation for severe ureteral injury.| | View in PubMed
- Techniques to optimize vascular control during laparoscopic donor nephrectomy.| | View in PubMed
- Anti-lymphocyte function-associated antigen-1 monoclonal antibody inhibits CD40 ligand-independent immune responses and prevents chronic vasculopathy in CD40 ligand-deficient mice.| | View in PubMed
- Successful long-term outcomes using pediatric en bloc kidneys for transplantation.| | View in PubMed
- Laparoscopic nephrectomy and autotransplantation for severe iatrogenic ureteral injuries.| | View in PubMed
- A calcineurin inhibitor-sparing regimen with sirolimus, mycophenolate mofetil, and anti-CD25 mAb provides effective immunosuppression in kidney transplant recipients with delayed or impaired graft function.| | View in PubMed
- Experience with the use of sirolimus in liver transplantation--use in patients for whom calcineurin inhibitors are contraindicated.| | View in PubMed
- Prolonged cold ischemia time obviates the benefits of 0 HLA mismatches in renal transplantation.| | View in PubMed
- The effect of age and prolonged cold ischemia times on the national allocation of cadaveric renal allografts.| | View in PubMed
- Flow cytometry crossmatching as a predictor of acute rejection in sensitized recipients of cadaveric renal transplants.| | View in PubMed
- Liver transplantation for autoimmune hepatitis: rejection and recurrence.| | View in PubMed
- Effect of systemic cyclosporine on tumor recurrence after liver transplantation in a model of hepatocellular carcinoma.| | View in PubMed
- Simultaneous pancreas-kidney transplantation: an overview of indications, complications, and outcomes.| | View in PubMed
- Hepatic artery pseudoaneurysm with hemobilia following angioplasty after liver transplantation.| | View in PubMed
- Risks associated with conversion of stable patients after liver transplantation to the microemulsion formulation of cyclosporine.| | View in PubMed
- Increased morbidity and mortality of simultaneous pancreas-renal transplantation in patients over 49 years of age.| | View in PubMed
- Liver transplantation improves survival of rats bearing hepatoma-3924A.| | View in PubMed
- Hepatotoxins and liver transplantation decrease pulmonary metastases in rats with hepatoma.| | View in PubMed
- Low postoperative wound infection rates are possible following simultaneous pancreas-kidney transplantation.| | View in PubMed
- Increased efficacy of CSA following rearterialization in the rat OLTX model.| | View in PubMed
- The increased efficacy and decreased nephrotoxicity of a cyclosporine liposome.| | View in PubMed
- Major histocompatibility complex class I deficiency prolongs islet allograft survival.| | View in PubMed
- Nonoperative management of biliary leaks after orthotopic liver transplantation.| | View in PubMed
- Maintenance immunosuppression with prednisone and RS-61443 alone following liver transplantation.| | View in PubMed
- Isolation of functional MHC class I-deficient islet cells.| | View in PubMed
- Orthotopic liver transplantation for end-stage alcoholic liver disease.| | View in PubMed
- Acute liver rejection: evaluation with cell-directed MR contrast agents in a rat transplantation model.| | View in PubMed
- A modified vascular "sleeve" anastomosis for rearterialization in orthotopic liver transplantation in rats.| | View in PubMed
- Similar clinical presentation of neurotoxicity following FK 506 and cyclosporine in a liver transplant recipient.| | View in PubMed
- Wound healing after anorectal surgery in human immunodeficiency virus-infected patients.| | View in PubMed
- Demonstration of local immunosuppression with methylprednisolone in the sponge matrix allograft model.| | View in PubMed
- Characterization of a cyclosporine-containing liposome.| | View in PubMed
- Comparison of three regimens for cytomegalovirus prophylaxis in 147 liver transplant recipients.| | View in PubMed
- MHC expression on human hepatocytes before and after isolation.| | View in PubMed