University of California San Francisco

Dr. Binh N. Trinh

Associate Professor of Surgery
Division of Cardiothoracic Surgery

Academic Office:
500 Parnassus Ave, MUW 405, Box 0118
San Francisco, CA 94143
Tel: (415) 353-8890
Email: [email protected] 
Admin: [email protected] 

Lung Transplant Program
500 Parnassus Ave., 6th Floor, Box 0115
San Francisco, CA 94143-0115
Tel: 415-353-4145

Thoracic Surgery & Oncology Program 
1600 Divisadero St., 4th Floor, Box 1705
San Francisco, CA 94115
Tel: 415-885-3882

Cardiac Surgery Program at SFVA
San Francisco VA Medical Center
4150 Clement St, bldg 112
San Francisco, CA 94121
Tel: (415) 221-4810


    Dr. Binh Trinh specializes in surgeries of the lung and chest. He cares for patients with various tumors of the chest, including lung cancer, esophageal cancer, mediastinal tumors and mesothelioma. He also treats noncancerous conditions such as emphysema, hyperhidrosis, diaphragmatic hernia and tracheal stenosis. He is especially interested in minimally invasive surgical techniques, including video-assisted thoracoscopic surgery and robotics applications. Trinh's research has explored the role of DNA methylation (a specific change to DNA that affects gene expression) in cancer, early cancer detection, and prognosis for lung and esophageal cancers. Trinh earned dual degrees from a combined medical and doctoral program at the Keck School of Medicine of the University of Southern California (USC). He went on to complete his general surgery residency at USC, followed by a fellowship in cardiothoracic surgery at UCSF. He joined the staff at UCSF in 2016. Trinh is an active member of the American College of Surgeons, Society of Thoracic Surgeons and American Medical Association.


    Institution Degree Dept or School End Date
    UCSF Medical Center Fellowship Cardiothoracic Surgery 2015
    Los Angeles County/USC Medical Center Residency General Surgery 2012
    Keck School of Medicine of USC 2005

    Board Certifications

    American Board of Surgery, General Surgery

    American Board of Thoracic Surgery, Thoracic and Cardiac Surgery 

    Clinical Expertise

    Minimally Invasive Surgery
    Video-Assisted Thoracoscopic Surgery (VATS)
    Lung Transplantation
    Bronchioloalveolar Carcinoma (BAC)
    Carcinoid Tumors
    Chest Wall Tumors
    Esophageal Cancer
    Lung Metastases
    Lung Volume Reduction Surgery
    Robotic Thoracic Surgery
    Malignant Mesothelioma
    Mediastinal Masses
    Minimally Invasive Thoracic Surgery
    Non-Small Cell Lung Cancer
    Small Cell Lung Cancer
    Thymoma & Thymic Carcinoma
    Tracheal Tumors

    Foreign Languages Spoken


    Program Affiliations

    Thoracic Oncology Program, UCSF Helen Diller Family Comprehensive Cancer Center

    Lung Transplantation, UCSF Heart and Lung Transplantation Program

    San Francisco Veterans Administration Hospital

    Research Interests

    Minimally invasive surgery
    Inflammation in lung carcinogenesis
    Clinical outcomes research
    Discovery of novel therapeutic targets in in thoracic malignancies
    Early Cancer Detection and Screening
    Lung cancer epigenetics and biomarkers


    1. Biofire pneumonia panel in lung donors: faster detection but limited pathogens.
      Nguyen A, Chen J, Isaza E, Panchal N, Deiter F, Hoover J, Trinh B, Hays SR, Golden JA, Singer JP, Brzezinski M, Greenland JR, Kukreja J| | View in PubMed
    2. Design and implementation of a digital health home spirometry intervention for remote monitoring of lung transplant function.
      Odisho AY, Liu AW, Maiorano AR, Bigazzi MOA, Medina E, Leard LE, Shah R, Venado A, Perez A, Golden J, Kleinhenz ME, Kolaitis NA, Maheshwari J, Trinh BN, Kukreja J, Greenland J, Calabrese D, Neinstein AB, Singer JP, Hays SR| | View in PubMed
    3. Intercostal Nerve Cryoanalgesia Versus Thoracic Epidural Analgesia in Lung Transplantation: A Retrospective Single-Center Study.
      Isaza E, Santos J, Haro GJ, Chen J, Weber DJ, Deuse T, Singer JP, Golden JA, Hays S, Trinh BN, Brzezinski M, Kukreja J| | View in PubMed
    4. Sjögren-Larsson syndrome caused by novel mutations in ALDH3A2 gene.
      Le NTA, Nguyen HLT, Trinh BN, Dang HH| | View in PubMed
    5. Early Postoperative Management of Lung Transplant Recipients.
      Trinh BN, Brzezinski M, Kukreja J| | View in PubMed
    6. The association of post-operative delirium with patient-reported outcomes and mortality after lung transplantation.
      DeBolt CL, Gao Y, Sutter N, Soong A, Leard L, Jeffrey G, Kleinhenz ME, Calabrese D, Greenland J, Venado A, Hays SR, Shah R, Kukreja J, Trinh B, Kolaitis NA, Douglas V, Diamond JM, Smith P, Singer J| | View in PubMed
    7. Lung transplantation from swimming pool drowning victims: A case series.
      Tsou S, Chen J, Brzezinski M, Hays S, Leard L, Singer JP, Trinh B, Kukreja J| | View in PubMed
    8. Risk Factors and Outcomes of Extracorporeal Membrane Oxygenation as a Bridge to Lung Transplantation.
      Kukreja J, Tsou S, Chen J, Trinh BN, Feng C, Golden JA, Hays S, Deuse T, Singer JP, Brzezinski M| | View in PubMed
    9. Reversal of TGFβ1-Driven Profibrotic State in Patients with Pulmonary Fibrosis.
      Chapman HA, Wei Y, Montas G, Leong D, Golden JA, Trinh BN, Wolters PJ, Le Saux CJ, Jones KD, Hills NK, Foster E, Oldham JM, Linderholm AL, Kotak P, Decaris M, Turner S, Song JW| | View in PubMed
    10. MethyLight and Digital MethyLight.
      Campan M, Weisenberger DJ, Trinh B, Laird PW| | View in PubMed
    11. Alterations in deoxyribonucleic acid (DNA) methylation patterns of Calca, Timp3, Mmp2, and Igf2r are associated with chronic cystitis in a cyclophosphamide-induced mouse model.
      Choi IS, Yu K, Kim J, De Guzman E, Weisenberger DJ, Oghamian S, Kim HJ, Lee KH, Carroll C, Trinh BN, Kim M, Houshdaran S, Laird PW, Jones PA, Warburton D, Liang G, Koh CJ| | View in PubMed
    12. MethyLight.
      Campan M, Weisenberger DJ, Trinh B, Laird PW| | View in PubMed
    13. DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight.
      Weisenberger DJ, Trinh BN, Campan M, Sharma S, Long TI, Ananthnarayan S, Liang G, Esteva FJ, Hortobagyi GN, McCormick F, Jones PA, Laird PW| | View in PubMed
    14. 2'-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1.
      Byun HM, Choi SH, Laird PW, Trinh B, Siddiqui MA, Marquez VE, Yang AS| | View in PubMed
    15. Dnmt1 deficiency leads to enhanced microsatellite instability in mouse embryonic stem cells.
      Kim M, Trinh BN, Long TI, Oghamian S, Laird PW| | View in PubMed
    16. Thymidylate synthase: a novel genetic determinant of plasma homocysteine and folate levels.
      Trinh BN, Ong CN, Coetzee GA, Yu MC, Laird PW| | View in PubMed
    17. DNA methyltransferase deficiency modifies cancer susceptibility in mice lacking DNA mismatch repair.
      Trinh BN, Long TI, Nickel AE, Shibata D, Laird PW| | View in PubMed