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Rong Wang, Ph.D.

Rong Wang, Ph.D.

Professor of Surgery
Division of Vascular and Endovascular Surgery
Mildred V. Strouss Endowed Chair in Vascular Surgery
Director, Laboratory for Accelerated Vascular Research
 

Contact Information

513 Parnassus Avenue, HSW 1618
San Francisco, CA 94143-0507
Phone: (415) 476-6820
rong.wang@ucsf.edu
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  • 1980-84, Sichuan University, B.S., Biology
  • 1984-88, Graduate School of Chinese Science and Technology University, Inst. of Genetics, M.S. candidate, Mammalian Genetics
  • 1988-93, University of North Carolina, Chapel Hill, Ph.D., Biology (Angiogenesis)
  • 1994-99, University of California, San Francisco, Postdoctoral Fellow, Cancer Biology
  • Angiogenesis Inhibitors
  • Arteriogenesis
  • Arteriovenous Malformations
  • Carcinoma, Hepatocellular
  • Collateral Vessel Formation
  • Developmental Biology
  • Developmental Growth
  • Embryonic Development
  • EphrinB2
  • Gene Expression Regulation
  • Neovascularization
  • Notch Pathway
  • Physiologic, Ischemia
  • Stem Cells
  • Vascular Development
  • Vascular Physiology

Rong Wang, Ph.D. is Professor of Surgery and Director of the Wang Lab. Previously, Dr. Wang had the distinction of being a post-doctoral fellow in the laboratory of Michael Bishop, MD, a winner of the Nobel Prize in Medicine and Chancellor of UCSF. Dr. Wang's team is engaged in state-of-the-art research involving key proteins necessary for blood vessel growth (angiogenesis) and arterial growth (arteriogenesis). They have found that the Notch 4 protein can cause dramatic blood vessel enlargement in adult animals and that the protein called focal adhesion kinase is essential for maintaining existing blood vessel structure.  The ability to encourage the growth of blood vessels can increase healing in traumatic wounds, promote recovery from strokes and heart attacks, or generate the growth of new pathways around blocked arteries in the lower limbs to reduce the potential of gangrene and possible amputation.

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  • Molecular Pathogenesis of Hereditary Hemorrhagic Telangiectasia
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    Feb 2020
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    Jan 2025
    Principal Investigator
  • Identifying Molecular Regulators of Hereditary Hemorrhagic Telangiectasia In a Novel Mouse Model
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    Jul 2019
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    Jun 2022
    Principal Investigator
  • Molecular Pathogenesis and Therapy for Critical Lim Ischemia
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    Jul 2018
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    Jun 2021
    Principal Investigator
  • RBPJ and EphrinB2 as Molecular Targets to Treat Brain Arteriovenous Malformation in Notch4-Induced Mouse Models
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    Sep 2016
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    Sep 2020
    Principal Investigator
  • Molecular Pathogenesis of Brain Arteriovenous Malformation
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    Aug 2010
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    Sep 2013
    Principal Investigator
  • Notch Signaling in Arterial-Venous Specification
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    Apr 2005
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    Mar 2010
    Principal Investigator
MOST RECENT PUBLICATIONS FROM A TOTAL OF 39
Data provided by UCSF Profiles, powered by CTSI
  1. Maloney R, Buuh ZY, Zhao Y, Wang RE. Site-specific antibody fragment conjugates for targeted imaging. Methods Enzymol. 2020; 638:295-320. View in PubMed
  2. Zhang Y, Fang C, Wang RE, Wang Y, Guo H, Guo C, Zhao L, Li S, Li X, Schultz PG, Cao YJ, Wang F. A tumor-targeted immune checkpoint blocker. Proc Natl Acad Sci U S A. 2019 08 06; 116(32):15889-15894. View in PubMed
  3. Wissler HL, Ehlerding EB, Lyu Z, Zhao Y, Zhang S, Eshraghi A, Buuh ZY, McGuth JC, Guan Y, Engle JW, Bartlett SJ, Voelz VA, Cai W, Wang RE. A Site-Specific ImmunoPET Tracer to Image PD-L1. Mol Pharm. 2019 Mar 15. View in PubMed
  4. Nguyen SV, Harhay DM, Bono JL, Smith TPL, Fields PI, Dinsmore BA, Santovenia M, Wang R, Bosilevac JM, Harhay GP. Comparative genomics of Salmonella enterica serovar Montevideo reveals lineage-specific gene differences that may influence ecological niche association. Microb Genom. 2018 08; 4(8). View in PubMed
  5. Cuervo H, Nielsen CM, Simonetto DA, Ferrell L, Shah VH, Wang RA. Endothelial notch signaling is essential to prevent hepatic vascular malformations in mice. Hepatology. 2016 10; 64(4):1302-1316. View in PubMed
  6. View All Publications

 

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