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Department of Surgery »  Faculty »  Transplant Surgery  »  Garrett R. Roll, M.D.
Garrett R. Roll, M.D., FACS

Garrett R. Roll, M.D., FACS

  • Associate Professor of Surgery
  • Division of Transplant Surgery

Contact Information

Academic Office
(415) 353-8725
garrett.roll@ucsf.edu
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Education

Boston College, BS, Finance, 1995-1999
Brandeis University, Post Baccalaureate, Premedical, 1999-2001
Temple University School of Medicine, MD, 2001-2005

Residencies

  • University of California, San Francisco, General Surgery, 2005-2012

Fellowships

  • UCSF Department of GI Hepatology Research Fellowship
  • University of California, San Francisco, Abdominal Transplant Surgery, 2012-2014
  • Senior international Fellow in liver transplant and retrieval, Queen Elizabeth Hospital, Birmingham, England

Board Certifications

  • American Board of Surgery, General Surgery

Clinical Interests

  • Transplantation
  • HBP surgery

Clinical Expertise

Research Interests

  • Cell therapy with hepatocytes and hepatocyte-like cells derived from stem cells.
  • Normothetic machine liver perfusion
  • Role of miRNA in liver regeneration

Biography

Dr. Roll is a general surgeon specializing in abdominal organ transplantation. He completed both general surgery training and the abdominal organ transplant fellowship at the University of California San Francisco. 

During his training, Dr. Roll spent 2 years in Dr. Holger Willenbring's laboratory investigating stem cell biology in the context of liver cell therapy, as well as normal and pathologic liver regeneration. His research concentrated on the use of hepatocyte-like cells derived from stem cells to be used in liver cell therapy. In particular, Dr. Roll investigated the regenerative capabilities of hepatocytes derived from induced pluripotent stem (iPS) cells. They used a genetically deficient mouse model of liver disease as a way to test the functional capabilities of these cells after transplantation. They were able to demonstrate that the profound proliferative capabilities of adult hepatocytes are retained by hepatocytes derived from iPS cells, and transplanting these cells rescued mice with liver failure. Dr. Roll also investigated the role of miRNA in liver regeneration, and the rejection of transplanted hepatocytes and hepatocyte-like cells. The principles of his research will remain valuable in liver and pancreas cell therapy translational science for years.

After fellowship Dr. Roll moved to England to become a Senior International Fellow in Liver Transplant and Multi Organ Procurement at Queen Elizabeth Hospital, Birmingham, one of the busiest liver transplant departments in the United Kingdom. There he gained valuable experience in the blossoming field of normothermic machine liver perfusion prior to returning to UCSF. 

Clinical Trials

Data provided by UCSF Profiles, powered by CTSI

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 103
Data provided by UCSF Profiles, powered by CTSI
  1. Sturdevant M, Ganesh S, Samstein B, Verna EC, Rodriguez-Davalos M, Kumar V, Abouljoud M, Andacoglu O, Askar M, Broering D, Emamaullee J, Emond JC, Haugen CE, Jesse MT, Kasahara M, Liapakis A, Mandelbrot D, Pillai A, Roll GR, Selzner N, Emre S, AST LDLT Consensus Conference Working Group. Advances and innovations in living donor liver transplant techniques, matching and surgical training: Meeting report from the living donor liver transplant consensus conference. Clin Transplant. 2023 Apr 11; e14968. View in PubMed
  2. Roll GR, Bray RA, Cooper M, Eagar TN, Gebel HM, Vranic GM, Hitchman KMK, Houp J, Kamoun M, Killian J, Kim J, Kumar V, Levine M, Lovasik BP, Lunow-Luke T, Parsons RF, Pattanayak V, Ranch D, Shah A, Stock PG, Timofeeva OA, Trofe-Clark J, Wongjirad C, Yeh H, Yi S, Rajalingam R. COVID-19 infection and vaccination rarely impact HLA antibody profile in waitlisted renal transplant candidates- a multicenter cohort. Hum Immunol. 2023 Apr; 84(4):278-285. View in PubMed
  3. Brown AE, Shui AM, Adelmann D, Mehta N, Roll GR, Hirose R, Syed SM. Number of Local Regional Therapies for Hepatocellular Carcinoma and Peri-Operative Outcomes after Liver Transplantation. Cancers (Basel). 2023 Jan 19; 15(3). View in PubMed
  4. Thiessen C, Wisel SA, Roll GR. Simultaneous thoracic and abdominal donation after circulatory death organ recovery: the abdominal surgeon's perspective. Curr Opin Organ Transplant. 2023 04 01; 28(2):139-144. View in PubMed
  5. Meier RPH, Kelly Y, Braun H, Maluf D, Freise C, Ascher N, Roberts J, Roll G. Comparison of Biliary Complications Rates After Brain Death, Donation After Circulatory Death, and Living-Donor Liver Transplantation: A Single-Center Cohort Study. Transpl Int. 2022; 35:10855. View in PubMed
  6. View All Publications

In the News

  • Garrett Roll Joins Division of Transplant Surgery

    UCSF Transplant Surgery - October 16, 2015
    The UCSF Division of Transplant Surgery is pleased to announce that Garrett R. Roll, M.D., FACS, recently joined the division as Assistant Professor Of Clinical Surgery. Dr. Roll is a transplant surgeon specializing in kidney, liver and pancreas transplantation, and in hepatobiliary surgery. Dr. Roll attended Boston College as an undergraduate and received his medical degree from Temple University School of Medicine. He completed his general surgery residency at UCSF, where he also completed a [...]

 

 
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