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Department of Surgery »  Faculty »  Transplant Surgery  »  Garrett R. Roll, M.D.
Garrett R. Roll, M.D., FACS

Garrett R. Roll, M.D., FACS

Assistant Professor of Surgery
Division of Transplant Surgery

Contact Information

Academic Office
(415) 353-8725
garrett.roll@ucsf.edu
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Boston College, BS, Finance, 1995-1999
Brandeis University, Post Baccalaureate, Premedical, 1999-2001
Temple University School of Medicine, MD, 2001-2005

  • University of California, San Francisco, General Surgery, 2005-2012
  • UCSF Department of GI Hepatology Research Fellowship
  • University of California, San Francisco, Abdominal Transplant Surgery, 2012-2014
  • Senior international Fellow in liver transplant and retrieval, Queen Elizabeth Hospital, Birmingham, England
  • American Board of Surgery, General Surgery
  • Transplantation
  • HBP surgery
  • Cell therapy with hepatocytes and hepatocyte-like cells derived from stem cells.
  • Normothetic machine liver perfusion
  • Role of miRNA in liver regeneration

Dr. Roll is a general surgeon specializing in abdominal organ transplantation. He completed both general surgery training and the abdominal organ transplant fellowship at the University of California San Francisco. 

During his training, Dr. Roll spent 2 years in Dr. Holger Willenbring's laboratory investigating stem cell biology in the context of liver cell therapy, as well as normal and pathologic liver regeneration. His research concentrated on the use of hepatocyte-like cells derived from stem cells to be used in liver cell therapy. In particular, Dr. Roll investigated the regenerative capabilities of hepatocytes derived from induced pluripotent stem (iPS) cells. They used a genetically deficient mouse model of liver disease as a way to test the functional capabilities of these cells after transplantation. They were able to demonstrate that the profound proliferative capabilities of adult hepatocytes are retained by hepatocytes derived from iPS cells, and transplanting these cells rescued mice with liver failure. Dr. Roll also investigated the role of miRNA in liver regeneration, and the rejection of transplanted hepatocytes and hepatocyte-like cells. The principles of his research will remain valuable in liver and pancreas cell therapy translational science for years.

After fellowship Dr. Roll moved to England to become a Senior International Fellow in Liver Transplant and Multi Organ Procurement at Queen Elizabeth Hospital, Birmingham, one of the busiest liver transplant departments in the United Kingdom. There he gained valuable experience in the blossoming field of normothermic machine liver perfusion prior to returning to UCSF. 

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MOST RECENT PUBLICATIONS FROM A TOTAL OF 77
Data provided by UCSF Profiles, powered by CTSI
  1. Whelan AM, Johansen KL, Brar S, McCulloch CE, Adey DB, Roll GR, Grimes B, Ku E. Association between Longer Travel Distance for Transplant Care and Access to Kidney Transplantation and Graft Survival in the United States. J Am Soc Nephrol. 2021 Mar 12. View in PubMed
  2. Roll GR, Roberts JP. With the proven tenacity of waitlist mortality shouldn't we resist the urge to make mountains out of statistical molehills? Liver Transpl. 2021 Feb 09. View in PubMed
  3. Amara D, Wisel SA, Braun HJ, Collisson EA, Friedlander T, Worner G, Roll GR, Hirose R, Stock PG. Metastatic Donor-derived Malignancies Following Simultaneous Pancreas-kidney Transplant: Three Case Reports and Management Strategies. Transplant Direct. 2021 Jan; 7(1):e636. View in PubMed
  4. Ku E, Whelan AM, McCulloch CE, Lee B, Niemann CU, Roll GR, Grimes BA, Johansen KL. Weighing the waitlist: Weight changes and access to kidney transplantation among obese candidates. PLoS One. 2020; 15(11):e0242784. View in PubMed
  5. Whelan AM, Johansen KL, McCulloch CE, Adelmann D, Niemann CU, Roll GR, Siyahian S, Grimes B, Ku E. Longer Distance From Dialysis Facility to Transplant Center Is Associated With Lower Access to Kidney Transplantation. Transplant Direct. 2020 Oct; 6(10):e602. View in PubMed
  6. View All Publications

 

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