Surgery Websites
Department of Surgery »  Faculty »  Transplant Surgery  »  Tara Sigdel, Ph.D.
Tara Sigdel, Ph.D.

Tara Sigdel, Ph.D.

Assistant Professor
Division of Transplant Surgery

Contact Information

513 Parnassus Ave, Med Sci
San Francisco CA 94143
tara.sigdel@ucsf.edu
Open Popup
  • B.Sc. (Biology and Chemistry) Tribhuvan University, Kathmandu, Nepal
  • M.Sc. (Chemistry) Tribhuvan University, Kathmandu, Nepal, Advisor: Prof. Vishwanath Pd. Agrawal, PhD
  • Ph.D. (Biochemistry), Miami University, Oxford, OH, Advisor: Prof. Michael Crowder, PhD
  • N/A
  • Postdoctoral Training, Dept of Pediatrics-nephrology, Stanford University, Stanford, CA
  • Advisor: Prof. Minnie Sarwal MD. PhD.
  • Bioinformatics
  • Biomarker DIscovery
  • High Throughput Data
  • Immunology
  • Kidney Transplantation
  • Liver Cancer
  • Organ Transplantation
  • Proteomics

Tara Sigdel, Ph.D. obtained his Ph.D. in biochemistry from Miami University (OH) followed by postdoctoral training in biomarker discovery, immunology, and organ transplantation at Stanford University under Professor Minnie Sarwal. Dr Sigdel joined the UCSF Department of Surgery in 2014 where he uses proteomics, immune response profiling, and gene expression analysis to discover sensitive and effective biomarkers that help in developing clinical tools for early diagnosis and improved patient monitoring. In collaboration with researchers at UCSF and other institutes, Dr. Sigdel is actively involved in identification of non-invasive biomarkers genes, peptides, proteins, and antibodies that monitor disease status after organ transplantation.

  • Pediatric Research Fund – CHRP Award, Stanford University, Stanford, CA, 2009-2010
  • Pediatric Research Fund – CHRP Award, Stanford University, Stanford, CA, 2008-2009
  • Deans Postdoctoral Fellowship, Stanford University, Stanford, CA, 2007-2008
  • Doctoral-Undergraduate Opportunities in Scholarship (DUOS) award for two consecutive years (2003 and, Miami University, Oxford, OH, 2003-2005
  • William Hale Charch Graduate Fellowship, Miami University, Oxford, OH, 2002-2003

Dr. Sigdel's research is driven by two major factors. First, there is an unprecedented pressure to deliver new and improved diagnostic and treatment options to patients. Second, due to improved understanding of biological intricacies with ever improving molecular assays have placed us in a much better position to look for disease specific biomarkers that once validated can be used in the clinics in order to provide timely and accurate assessment of health status of patients.

Most recent publications from a total of 70
  1. Sigdel TK, Mercer N, Nandoe S, Nicora CD, Burnum-Johnson K, Qian WJ, Sarwal MM. Urinary Virome Perturbations in Kidney Transplantation. Front Med (Lausanne). 2018; 5:72. View in PubMed
  2. Sigdel TK, Nicora CD, Qian WJ, Sarwal MM. Optimization for Peptide Sample Preparation for Urine Peptidomics. Methods Mol Biol. 2018 Apr 06. View in PubMed
  3. Pineda S, Sigdel TK, Chen J, Jackson AM, Sirota M, Sarwal MM. Corrigendum: Novel Non-Histocompatibility Antigen Mismatched Variants Improve the Ability to Predict Antibody-Mediated Rejection Risk in Kidney Transplant. Front Immunol. 2018; 9:107. View in PubMed
  4. Pineda S, Sigdel TK, Chen J, Jackson AM, Sirota M, Sarwal MM. Novel Non-Histocompatibility Antigen Mismatched Variants Improve the Ability to Predict Antibody-Mediated Rejection Risk in Kidney Transplant. Front Immunol. 2017; 8:1687. View in PubMed
  5. Towfighi P, Shaw J, Sigdel T. Fractionation of Soluble Proteins Using DEAE-Sepharose, SP-Sepharose, and Phenyl Sepharose Chromatographies for Proteomics. Methods Mol Biol. 2017 Dec 02. View in PubMed
  6. Sigdel TK, Sarwal MM. Discovery of Immune Reactive Human Proteins by High-Density Protein Arrays and Customized Validation of Potential Biomarkers by ELISA. Methods Mol Biol. 2017 Nov 08. View in PubMed
  7. Gao Y, Wang H, Nicora CD, Shi T, Smith RD, Sigdel TK, Sarwal MM, Camp DG, Qian WJ. LC-SRM-Based Targeted Quantification of Urinary Protein Biomarkers. Methods Mol Biol. 2017 Nov 08. View in PubMed
  8. Roedder S, Sigdel T, Hsieh SC, Cheeseman J, Metes D, Macedo C, Reed EF, Gritsch HA, Zeevi A, Shapiro R, Kirk AD, Sarwal MM. Expression of Mitochondrial-Encoded Genes in Blood Differentiate Acute Renal Allograft Rejection. Front Med (Lausanne). 2017; 4:185. View in PubMed
  9. Chandran S, Tang Q, Sarwal M, Laszik ZG, Putnam AL, Lee K, Leung J, Nguyen V, Sigdel T, Tavares EC, Yang JYC, Hellerstein M, Fitch M, Bluestone JA, Vincenti F. Polyclonal Regulatory T Cell Therapy for Control of Inflammation in Kidney Transplants. Am J Transplant. 2017 Nov; 17(11):2945-2954. View in PubMed
  10. Sigdel TK, Sarwal MM. Assessment of Circulating Protein Signatures for Kidney Transplantation in Pediatric Recipients. Front Med (Lausanne). 2017; 4:80. View in PubMed
  11. View All Publications
Publications provided by UCSF Profiles, powered by CTSI at UCSF. View profile of Tara Sigdel, Ph.D.
Please note: UCSF Profiles publications are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact CTSI for help.

Site Directory
    X