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Department of Surgery »  Faculty »  Transplant Surgery  »  Garrett R. Roll, M.D.
Garrett R. Roll, M.D., FACS

Garrett R. Roll, M.D., FACS

Assistant Professor of Surgery
Division of Transplant Surgery

Contact Information

Academic Office
(415) 353-8725
garrett.roll@ucsf.edu
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Boston College, BS, Finance, 1995-1999
Brandeis University, Post Baccalaureate, Premedical, 1999-2001
Temple University School of Medicine, MD, 2001-2005

  • University of California, San Francisco, General Surgery, 2005-2012
  • UCSF Department of GI Hepatology Research Fellowship
  • University of California, San Francisco, Abdominal Transplant Surgery, 2012-2014
  • Senior international Fellow in liver transplant and retrieval, Queen Elizabeth Hospital, Birmingham, England
  • American Board of Surgery, General Surgery
  • Transplantation
  • HBP surgery
  • Cell therapy with hepatocytes and hepatocyte-like cells derived from stem cells.
  • Normothetic machine liver perfusion
  • Role of miRNA in liver regeneration

Dr. Roll is a general surgeon specializing in abdominal organ transplantation. He completed both general surgery training and the abdominal organ transplant fellowship at the University of California San Francisco. 

During his training, Dr. Roll spent 2 years in Dr. Holger Willenbring's laboratory investigating stem cell biology in the context of liver cell therapy, as well as normal and pathologic liver regeneration. His research concentrated on the use of hepatocyte-like cells derived from stem cells to be used in liver cell therapy. In particular, Dr. Roll investigated the regenerative capabilities of hepatocytes derived from induced pluripotent stem (iPS) cells. They used a genetically deficient mouse model of liver disease as a way to test the functional capabilities of these cells after transplantation. They were able to demonstrate that the profound proliferative capabilities of adult hepatocytes are retained by hepatocytes derived from iPS cells, and transplanting these cells rescued mice with liver failure. Dr. Roll also investigated the role of miRNA in liver regeneration, and the rejection of transplanted hepatocytes and hepatocyte-like cells. The principles of his research will remain valuable in liver and pancreas cell therapy translational science for years.

After fellowship Dr. Roll moved to England to become a Senior International Fellow in Liver Transplant and Multi Organ Procurement at Queen Elizabeth Hospital, Birmingham, one of the busiest liver transplant departments in the United Kingdom. There he gained valuable experience in the blossoming field of normothermic machine liver perfusion prior to returning to UCSF. 

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MOST RECENT PUBLICATIONS FROM A TOTAL OF 65
Data provided by UCSF Profiles, powered by CTSI
  1. Syed SM, Gardner J, Roll G, Webber A, Mehta N, Shoji J, Adelmann D, Niemann C, Braun HJ, Mello A, Yao F, Posselt A, Kang SM, Hirose R, Roberts J, Feng S, Ascher N, Stock P, Freise C. COVID-19 and Abdominal Transplant: A Stepwise Approach to Practice During Pandemic Conditions. Transplantation. 2020 Jun 29. View in PubMed
  2. Silverstein J, Roll G, Dodge JL, Grab JD, Yao FY, Mehta N. Donation after Circulatory Death is Associated with Similar Post-Transplant Survival in All but the Highest Risk Hepatocellular Carcinoma Patients. Liver Transpl. 2020 Jun 12. View in PubMed
  3. Hannon V, Kothari RP, Zhang L, Bokoch MP, Hill R, Roll GR, Mello A, Feiner JR, Liu KD, Niemann CU, Adelmann D. The Association Between Vena Cava Implantation Technique and Acute Kidney Injury After Liver Transplantation. Transplantation. 2020 May 25. View in PubMed
  4. Neidlinger NA, Brown C, Wood P, Traseger J, Lebovitz D, Cauwels R, Syed S, Parekh JR, Roll GR. Understanding the Final Disposition of Livers Declined After the Start of Procurement: A Nationwide Organ Procurement Organization Effort. Liver Transpl. 2020 May 17. View in PubMed
  5. Kubal C, Roll GR, Ekser B, Muiesan P. Donation after circulatory death liver transplantation: What are the limits for an acceptable DCD graft? Int J Surg. 2020 May 07. View in PubMed
  6. View All Publications

 

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