Department of Surgery »  Faculty »  Transplant Surgery  »  Andrew M. Posselt, M.D., Ph.D.
Andrew M. Posselt, M.D., Ph.D., FACS

Andrew M. Posselt, M.D., Ph.D., FACS

Professor of Surgery
Division of Transplant Surgery
Director, Pancreatic Islet Transplant Program

Contact Information

Academic Office
(415) 514-5606
andrew.posselt@ucsf.edu
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  • Stanford University, B.S., Biology, 1981-85
  • University of Pennsylvania, M.D., Medicine, 1985-93
  • University of Pennsylvania, Ph.D., Immunology, 1989-93
  • University of California, San Francisco, Resident, Medicine, 1993-96
  • University of California, San Francisco, Resident, Surgery, 1996-00
  • University of California, San Francisco, Fellow, Transplant Surgery, 2000-02
  • American Board of Internal Medicine, 1996
  • American Board of Surgery, 2002
  • Pancreatic Islet Transplantation Program
  • Bariatric Surgery Center
  • ABO-Incompatible Kidney Transplant Program
  • Autologous Islet Cell Transplantation
  • Bariatric Surgery (Laparoscopic and Open)
  • Bile Duct Injuries
  • Bile Duct Strictures
  • Choledochal Cyst Disease
  • End-Stage Kidney Disease
  • Fulminant Hepatic Failure
  • Hepatitis B
  • Hepatitis C
  • Hepatocellular Carcinoma (Primary Liver Cancer)
  • Islet Cell Transplantation
  • Kidney Transplantation
  • Laparoscopic Donor Nephrectomy
  • Liver Cysts
  • Liver Transplantation
  • Nonalcoholic Fatty Liver Disease
  • Pancreas Transplantation
  • Pediatric Kidney Transplantation
  • Pediatric Liver Transplantation
  • Portal Hypertension
  • Assessment of long-term clinical outcomes in kidney donors
  • Clinical outcomes of bariatric surgery in patients with end-stage kidney or liver disease
  • Metabolic and biochemical consequences of bariatric surgery
  • Transplantation of pancreatic islets as treatment for type 1 diabetes mellitus

Dr. Andrew Posselt is an attending multi-organ transplant surgeon at UCSF and Director of the ABO-Incompatible Kidney Transplant Program as well as Co-director of the Pancreatic Islet Transplant Program and the Bariatric Surgery Program.  Dr. Posselt specializes in adult and pediatric kidney, liver and pancreas transplantation; laparoscopic donor nephrectomy; and laparoscopic as well as open bariatric surgery.  Dr. Posselt's current research interests include: 1) transplantation of pancreatic islets for the treatment of type 1 diabetes mellitus; 2) assessment of long-term renal function in kidney donors after donor nephrectomy; 3) immunologic and tolerogenic properties of embryonic stem cells; and 4) bariatric surgery in patients awaiting transplant. 

 
Most recent publications from a total of 84
  1. Kim TY, Schwartz AV, Li X, Xu K, Black DM, Petrenko DM, Stewart L, Rogers SJ, Posselt AM, Carter JT, Shoback DM, Schafer AL. Bone Marrow Fat Changes After Gastric Bypass Surgery Are Associated With Loss of Bone Mass. J Bone Miner Res. 2017 Aug 09. View in PubMed
  2. Harbell JW, Morgan T, Feldstein VA, Roll GR, Posselt A, Kang SM, Feng S, Hirose R, Freise CE, Stock P. Splenic Vein Thrombosis Following Pancreas Transplantation: Identification of Factors That Support Conservative Management. Am J Transplant. 2017 Jul 14. View in PubMed
  3. Ricordi C, Goldstein JS, Balamurugan AN, Szot GL, Kin T, Liu C, Czarniecki CW, Barbaro B, Bridges ND, Cano J, Clarke WR, Eggerman TL, Hunsicker LG, Kaufman DB, Khan A, Lafontant DE, Linetsky E, Luo X, Markmann JF, Naji A, Korsgren O, Oberholzer J, Turgeon NA, Brandhorst D, Friberg AS, Lei J, Wang LJ, Wilhelm JJ, Willits J, Zhang X, Hering BJ, Posselt AM, Stock PG, Shapiro AMJ. Erratum. National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities. Diabetes 2016;65:3418-3428. Diabetes. 2017 Sep; 66(9):2531. View in PubMed
  4. Song S, Blaha C, Moses W, Park J, Wright N, Groszek J, Fissell W, Vartanian S, Posselt AM, Roy S. Correction: An intravascular bioartificial pancreas device (iBAP) with silicon nanopore membranes (SNM) for islet encapsulation under convective mass transport. Lab Chip. 2017 Jun 27; 17(13):2334. View in PubMed
  5. Wisel SA, Gardner JM, Roll GR, Harbell J, Freise CE, Feng S, Kang SM, Hirose R, Kaufman DB, Posselt AM, Stock PG. Pancreas-After-Islet Transplantation in Nonuremic Type 1 Diabetes: A Strategy for Restoring Durable Insulin Independence. Am J Transplant. 2017 Sep; 17(9):2444-2450. View in PubMed
  6. Song S, Blaha C, Moses W, Park J, Wright N, Groszek J, Fissell W, Vartanian S, Posselt AM, Roy S. An intravascular bioartificial pancreas device (iBAP) with silicon nanopore membranes (SNM) for islet encapsulation under convective mass transport. Lab Chip. 2017 May 16; 17(10):1778-1792. View in PubMed
  7. Yamanaga S, Posselt AM, Freise CE, Kobayashi T, Tavakol M, Kang SM. A Single Perioperative Injection of Dexamethasone Decreases Nausea, Vomiting, and Pain after Laparoscopic Donor Nephrectomy. J Transplant. 2017; 2017:3518103. View in PubMed
  8. Ricordi C, Goldstein JS, Balamurugan AN, Szot GL, Kin T, Liu C, Czarniecki CW, Barbaro B, Bridges ND, Cano J, Clarke WR, Eggerman TL, Hunsicker LG, Kaufman DB, Khan A, Lafontant DE, Linetsky E, Luo X, Markmann JF, Naji A, Korsgren O, Oberholzer J, Turgeon NA, Brandhorst D, Chen X, Friberg AS, Lei J, Wang LJ, Wilhelm JJ, Willits J, Zhang X, Hering BJ, Posselt AM, Stock PG, Shapiro AM. National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities. Diabetes. 2016 11; 65(11):3418-3428. View in PubMed
  9. Kasiske BL, Kumar R, Kimmel PL, Pesavento TE, Kalil RS, Kraus ES, Rabb H, Posselt AM, Anderson-Haag TL, Steffes MW, Israni AK, Snyder JJ, Singh RJ, Weir MR. Abnormalities in biomarkers of mineral and bone metabolism in kidney donors. Kidney Int. 2016 Oct; 90(4):861-8. View in PubMed
  10. Hering BJ, Clarke WR, Bridges ND, Eggerman TL, Alejandro R, Bellin MD, Chaloner K, Czarniecki CW, Goldstein JS, Hunsicker LG, Kaufman DB, Korsgren O, Larsen CP, Luo X, Markmann JF, Naji A, Oberholzer J, Posselt AM, Rickels MR, Ricordi C, Robien MA, Senior PA, Shapiro AM, Stock PG, Turgeon NA. Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia. Diabetes Care. 2016 Jul; 39(7):1230-40. View in PubMed
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  • Lorelei Batty

    A Complex Procedure for Life-Threatening Pancreatitis

    A Complex Procedure for Life-Threatening Pancreatitis One morning in December 2014, Lorelei Batty woke up screaming in pain and sick to her stomach. Emergency room doctors in her hometown of Santa Maria, Calif., thought the 3-year-old had the flu and sent her home. But Lorelei didn't improve over the next week and a half, and a far more serious diagnosis soon came in: pancreatitis, an inflammation of the pancreas that's rare in children and can be difficult to treat. After spending most of the next nine months in seven different hospitals with deteriorating health, Lorelei finally[...]
    Story Categories:
  • Mike Schofield

    Two-Time Transplant Recipient Meets Donor's Family

    Michael Schofield
    After Michael Schofield had his first islet cell transplant in April 2012, he wrote a letter thanking the family of his donor. It was over a year before he heard back from the donor’s mother. That's when he learned they had more in common than the young man whose cells Michael was carrying. He was en route to meet the mother last June, when he got another exciting piece of news: UCSF had a donor for the second islet transplant that he needed. In the space of a week he connected with one donor's family and started a new connection with another.[...]
    Story Categories: Type 1 Diabetes
  • Susie Rember

    Insulin-Free Patient Grateful for Islet Transplant

    Susie Rember
    Susan Rember was eight years old when she was diagnosed with type 1 diabetes in 1957. At the time, diabetics used glass syringes, tested their urine for sugar levels and were told they could never live a normal life. But Rember was mostly free from major complications for 50 years, until she suffered a heart attack in 2005. She had a quintuple by-pass, but when three of the grafted vessels immediately failed, the Denver-based artist began exploring the possibility of an islet transplant. In 2007, she got new islets through a clinical study[...]
    Story Categories: Type 1 Diabetes
  • Sandy Raffi-Rashed

    Surgery Ends Decades of Obesity, New Life Begins

    Sandy Raffi-Rashed after losing 185 pounds
    Sandy Raffi-Rashed after losing 185 poundsWhen Sandy Raffi-Rashed, a 60-year-old mother of two, went to the airport to pick up her youngest son visiting from Manhatten, he didn't recognize her. "I was waving to him from the car and he thought, 'Who is that strange woman waving at me?" says Raffi-Rashed, of Novato, Calif. "Then, when he saw me, he said, 'Oh my God!'" His mother had undergone a transformation after weight-loss surgery. In July of 2011, Raffi-Rashed had gastric bypass surgery at the Bariatric Surgery Center at UCSF Medical[...]
    Story Categories: Laparoscopic Gastric BypassObesityPost-Bariatric Body Contouring
  • Kim Mendes

    Insulin Free for the First Time in 40 Years

    Kim Mendes
    Bay Area native Kim Mendes has lived most of her life with Type 1 diabetes and the disease has taken a heavy toll on her body, causing a host of medical problems including peripheral neuropathy, heart disease, kidney disease and a compromised immune system. She got an islet transplant in 2010 and has been insulin free ever since. How long have you had diabetes? This is my 40th year as a Type 1 diabetic. I was seven years old when I was diagnosed. I had fallen into a diabetic coma and insulin brought me out. From that moment on I was[...]
    Story Categories: Type 1 Diabetes

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