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Department of Surgery »  Faculty »  General Surgery »  Robert S. Warren, M.D.
Robert S. Warren, M.D.

Robert S. Warren, M.D.

Professor of Surgery
Division of General Surgery
Director, Surgical Oncology Lab

Contact Information

1600 Divisadero Street
San Francisco, California 94143-1932
Academic Telephone: (415) 353-9294
Fax: (415) 353-9296
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  • 1969-71, University of Minnesota B.A.,  Physiology, Magna Cum Laude
  • 1976-80, University of Minnesota Medical School, Minneapolis M.D.
  • 1980-81, University of Minnesota, Intern, Surgery
  • 1981-88, University of Minnesota, Resident, Surgery
  • 1980-81, University of Minnesota, Postdoctoral Fellow, Surgery
  • 1981-88, University of Minnesota, Postdoctoral Fellow, Surgery
  • 1983-86, Memorial Sloan-Kettering Cancer Center, Fellow, Oncology Research
  • 1983-86, Memorial Sloan-Kettering Cancer Center, Postdoctoral Fellow, Oncology
  • American Board of Surgery, 1989
  • Surgical Oncology Program
  • Surgical Oncology Laboratory
  • UCSF Helen Diller Family Comprehensive Cancer Center
  • UCSF Department of Surgery

Robert S. Warren, M.D. is a Professor of Surgery and a specialist in gastrointestinal and liver cancer. He earned a medical degree at the University of Minnesota, where he completed a general surgery residency. After completing an oncology research fellowship at Memorial Sloan-Kettering Cancer Center in New York, he was an associate physician at Rockefeller University in New York. A board-certified surgeon, Dr. Warren joined UCSF Medical Center in 1988. Highly respected by his peers, Dr. Warren was named to the list of U.S. News "America's Top Doctors," a distinction reserved for the top 1% of physicians in the nation for a given specialty. His research focuses on the biology of colorectal cancer and how it spreads.

Dr. Warren is involved in clinical and laboratory research, which has centered on the biology of colorectal cancer metastasis that includes Vascular Endothelial Growth Factor (VEGF), Insulin-Like Growth Factors and Their Binding Proteins AS Modulators of Growth of Colorectal Cancer Metastases and Cytogenetics of Colorectal Cancer Metastasis. The laboratory work focuses on two areas: 1) autocrine growth factors and angiogenesis in colorectal cancer 2) molecular features which predict clinical outcome in primary and metastatic colorectal cancer.

  • Biology of colorectal cancer metastasis
  • Molecular features which predict clinical outcome in primary and metastatic colorectal cancer
  • Autocrine growth factors and angiogenesis in colorectal cancer
  • Vascular Endothelial Growth Factor (VEGF) Hypoxia and Colon Cancer
  • Insulin-Like Growth Factors and Their Binding Proteins As Modulators of Growth of Colorectal Cancer Metastases
  • Cytogenetics of Colorectal Cancer Metastasis
Most recent publications from a total of 65
  1. Kasai Y, Hirose K, Corvera CU, Kim GE, Hope TA, Shih BE, Harun N, Kim MO, Warren RS, Bergsland EK, Nakakura EK. Residual tumor volume discriminates prognosis after surgery for neuroendocrine liver metastasis. J Surg Oncol. 2019 Dec 11. View in PubMed
  2. Kasai Y, Mahuron K, Hirose K, Corvera CU, Kim GE, Hope TA, Shih BE, Warren RS, Bergsland EK, Nakakura EK. Prognostic impact of a large mesenteric mass >2?cm in ileal neuroendocrine tumors. J Surg Oncol. 2019 Dec; 120(8):1311-1317. View in PubMed
  3. Donner DB, Nakakura EK, Venook AP, Lenz HJ, Zhang W, Hwang J, Bergsland EK, Lin MH, Toriguchi K, Antonia RJ, Warren RS. High thymidylate synthase gene expression predicts poor outcome after resection of hepatocellular carcinoma. PLoS One. 2019; 14(7):e0219469. View in PubMed
  4. Gbenedio OM, Bonnans C, Grun D, Wang CY, Hatch AJ, Mahoney MR, Barras D, Matli M, Miao Y, Garcia KC, Tejpar S, Delorenzi M, Venook AP, Nixon AB, Warren RS, Roose JP, Depeille P. RasGRP1 is a potential biomarker to stratify anti-EGFR therapy response in colorectal cancer. JCI Insight. 2019 Jun 25; 5. View in PubMed
  5. Donner DB, Ruan DT, Toriguchi K, Bergsland EK, Nakakura EK, Lin MH, Antonia RJ, Warren RS. Mitogen Inducible Gene-6 Is a Prognostic Marker for Patients with Colorectal Liver Metastases. Transl Oncol. 2019 Mar; 12(3):550-560. View in PubMed
  6. Chamberlain CE, German MS, Yang K, Wang J, VanBrocklin H, Regan M, Shokat KM, Ducker GS, Kim GE, Hann B, Donner DB, Warren RS, Venook AP, Bergsland EK, Lee D, Wang Y, Nakakura EK. A Patient-derived Xenograft Model of Pancreatic Neuroendocrine Tumors Identifies Sapanisertib as a Possible New Treatment for Everolimus-resistant Tumors. Mol Cancer Ther. 2018 12; 17(12):2702-2709. View in PubMed
  7. Rajaram S, Heinrich LE, Gordan JD, Avva J, Bonness KM, Witkiewicz AK, Malter JS, Atreya CE, Warren RS, Wu LF, Altschuler SJ. Sampling strategies to capture single-cell heterogeneity. Nat Methods. 2017 Oct; 14(10):967-970. View in PubMed
  8. Hege KM, Bergsland EK, Fisher GA, Nemunaitis JJ, Warren RS, McArthur JG, Lin AA, Schlom J, June CH, Sherwin SA. Safety, tumor trafficking and immunogenicity of chimeric antigen receptor (CAR)-T cells specific for TAG-72 in colorectal cancer. J Immunother Cancer. 2017; 5:22. View in PubMed
  9. Niedzwiecki D, Frankel WL, Venook AP, Ye X, Friedman PN, Goldberg RM, Mayer RJ, Colacchio TA, Mulligan JM, Davison TS, O'Brien E, Kerr P, Johnston PG, Kennedy RD, Harkin DP, Schilsky RL, Bertagnolli MM, Warren RS, Innocenti F. Reply to L. Casadaban et al. J Clin Oncol. 2017 04 20; 35(12):1373-1374. View in PubMed
  10. Niedzwiecki D, Hasson RM, Lenz HJ, Ye C, Redston M, Ogino S, Fuchs CS, Compton CC, Mayer RJ, Goldberg RM, Colacchio TA, Saltz LB, Warren RS, Bertagnolli MM. A Study of Thymidylate Synthase Expression as a Biomarker for Resectable Colon Cancer: Alliance (Cancer and Leukemia Group B) 9581 and 89803. Oncologist. 2017 01; 22(1):107-114. View in PubMed
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