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Lucy Zumwinkle Kornblith, M.D., FACS
- Associate Professor of Surgery
- Division of General Surgery
- Trauma and Surgical Critical Care
- Zuckerberg San Francisco General Hospital
- The Director of Gender Equity
- Co-chair, Muriel Steele Society
Contact Information
Education
University of California Santa Barbara, Santa Barbara, CA; BS, Biological Sciences, 2005
University of Colorado, Denver, CO; MD, 2009
University of California, San Francisco, CA 2019, Diversity, Equity, and Inclusion Champion Training
Fellowships
- UCSF, Surgical Critical Care and Trauma Surgery, 2016-17
- UCSF, Trauma & Emergency Care, 2017-18
Biography
Lucy Zumwinkle Kornblith, M.D., F.A.C.S. received her undergraduate degree from University of California Santa Barbara, her M.D. from the University of Colorado, completed her General Surgery residency at the University of California San Francisco (UCSF), a Trauma and Critical Care Clinical Translational Research Fellowship at UCSF, and subspecialty training in Trauma and Acute Care Surgery and Surgical Critical Care at UCSF prior to joining the faculty at UCSF.
She clinically practices Trauma Surgery, Acute Care Surgery, and Surgical Critical Care. She has played a pivotal role in the translational study of blood system failure after injury, centrally focused on post-injury platelet biology. Her research program is multi-pronged, covering 1) Translational research to identify novel biology of blood system failure through the lens of platelets, 2) Large observational studies to identify predictors of bad outcomes after injury, and 3) Clinical trials investigating therapeutics and resuscitation strategies for injured patients. Her research program has been funded by the National Institutes of Health, the Department of Defense, the American College of Surgeons, the Eastern Association for the Surgery of Trauma, the UCSF School of Medicine Irene Perstein Award, and the Doris Duke Charitable Foundation. Dr. Kornblith is the Department of Surgery Director of Gender Equity and a co-chair of the UCSF Department of Surgery Muriel Steele Society, an inclusive community dedicated to inspiring, supporting, and promoting 400+ women surgeons so they can thrive at all stages of their careers.
Awards & Honors
Award
Confired By
Date
Mentoring Overview
Dr. Kornblith is a mentor for a diverse learner pool. Her mentees are in pursuit of academic scientific agendas across various points in their careers, various specialties, and various institutions (including other University of California campuses). She works with undergraduate students from various universities to learn important activities of translational research including data collection via chart review, clotting assays, plasma organization, transport of biospecimens, and laboratory clerical activities. She serves as a mentor for UCSF medical students in the UCSF School of Medicine Deep Explore program and Clinical Microsystems Course, and has UCSF medical students in her laboratory. She is a designated clinical and research advisor to residents in the UCSF Department of Surgery. Dr. Kornblith was awarded the 2021 UCSF CTSI Mentor of the Year Award. In addition. Dr. Kornblith mentors beyond UCSF via participating on Thesis Statement Review Committees and dissertation committees at the University of California, Berkeley. In addition, Dr. Kornblith mentors in the San Francisco BUILD Student Training program which is an NIH-funded pipeline/pathway program support historically underrepresented undergraduate students from San Francisco State University to pursue graduate study (PhD, MD-PhD, or Masters) in the biomedical sciences.
Available to Mentor as: (Review Mentor Role Definitions): · Career Mentor · Co-Mentor · Lead Research / Scholarly Mentor · Project Mentor
Contact for Mentoring:
- · Email (see above)
Learn about the Faculty Mentoring Program and the CTSI Mentor Development Program
Collaboration Interests
Dr. Kornblith is a surgeon scientist focused on translational studies in the field of Trauma with a particular interest in elucidating the mechanisms and mediators of trauma-induced coagulopathy and resuscitation techniques for post-traumatic hemorrhage. She has essential research experience studying post-injury platelet biology and technical expertise in functional laboratory measures of coagulation. She has extensive experience and expertise in the nuances of biospecimen collection in severely injured patients. She is trained in clinical research design and biostatistics from the Clinical and Translational Science Institute at UCSF. She is funded by the National Institutes of Health, the Department of Defense, the American College of Surgeons, the Eastern Association for the Surgery of Trauma, the UCSF School of Medicine Irene Perstein Award, and the Doris Duke Chartiable Foundation. She collaborates cross-disciplinary and multi-institutionally to advance knowledge within her field of interest.
I am interested in:
- Academic Collaboration
- Academic Senate Committee Service
- Multicenter Clinical Research
- Community and Stakeholder Organizations
- Companies and Entrepreneurs
- Press
- Prospective Donors
- Physician-Scientist
Research & Funding
Data provided by UCSF Profiles, powered by CTSI
ORCID iD: 0000-0002-1861-9691 
- The Platelet Transcriptome and Organ Failure After Injury: Discovering Molecular Biomarkers and Preventative Targets through Interrogating Novel RNA ModificationsSponsor: NIH/NIGMSSponsor ID: 1R35GM150656-01Funding Period:Sep 2023-Aug 2028Principal Investigator
- Platelet Biology: Mechanisms and OutcomesSponsor: George H. A. Clowes, Jr., MD, FACS, Memorial Research Career Development Award, American College of SurgeonsSponsor ID:Funding Period:Jul 2023-Jun 2028Principal Investigator
- Post-Injury Platelet Biology: Mechanisms and OutcomesSponsor: NIHSponsor ID: K23GM130892Funding Period:Sep 2018-Aug 2023Principal Investigator
- Freeze Dried Platelet Extracellular Vesicles as a Hemostatic Adjunct to Resuscitation for Prolonged Field CareSponsor: DOD/USAMRAASponsor ID: W81XWH2010216Funding Period:Jul 2020-Jun 2022Co-Investigator
- The ACCT Study: Assessing COVID-19 Associated Coagulopathy and ThrombosisSponsor: NIH/NCATSSponsor ID: UL1TR001872Funding Period:Jun 2020-May 2021Primary Investigator
- Post-Injury Platelet GenomicsSponsor: University of California School of Medicine Irene Perstein AwardSponsor ID:Funding Period:Aug 2019-Jul 2020Primary Investigator
- Post-Injury Platelet FunctionSponsor: Eastern Association for the Surgery of TraumaSponsor ID: P0526402Funding Period:Aug 2018-Jul 2019Principal Investigator
Clinical Trials
Data provided by UCSF Profiles, powered by CTSI
- Study ID: NCT05966454Start Date: Jun 2023Estimated Completion Date: Jun 2025Condition(s): Appendicitis
- Study ID: NCT04667468Start Date: Jun 2021Estimated Completion Date: Aug 2023Condition(s): Trauma, Hemorrhage
- Study ID: NCT03682757Start Date: Sep 2018Estimated Completion Date: Sep 2023Condition(s): Wound and Injuries, Blood Platelets, Endothelium
Publications
MOST RECENT PUBLICATIONS FROM A TOTAL OF 133
Data provided by UCSF Profiles, powered by CTSI
- Smilowitz NR, Hade EM, Kornblith LZ, Castellucci LA, Cushman M, Farkouh M, Gong MN, Heath A, Hunt BJ, Kim KS, Kindzelski A, Lawler P, Leaf DE, Goligher E, Leifer ES, McVerry BJ, Reynolds HR, Zarychanski R, Hochman JS, Neal MD, Berger JS. Effect of therapeutic-dose heparin on severe acute kidney injury and death in noncritically ill patients hospitalized for COVID-19: a prespecified secondary analysis of the ACTIV4a and ATTACC randomized trial. Res Pract Thromb Haemost. 2023 Aug; 7(6):102167. View in PubMed
- Solomon SD, Lowenstein CJ, Bhatt AS, Peikert A, Vardeny O, Kosiborod MN, Berger JS, Reynolds HR, Mavromichalis S, Barytol A, Althouse AD, Luther JF, Leifer ES, Kindzelski AL, Cushman M, Gong MN, Kornblith LZ, Khatri P, Kim KS, Baumann Kreuziger L, Wahid L, Kirwan BA, Geraci MW, Neal MD, Hochman JS, ACTIV4a Investigators. Effect of the P-Selectin Inhibitor Crizanlizumab on Survival Free of Organ Support in Patients Hospitalized for COVID-19: A Randomized Controlled Trial. Circulation. 2023 08; 148(5):381-390. View in PubMed
- Berger JS, Neal MD, Kornblith LZ, Gong MN, Reynolds HR, Cushman M, Althouse AD, Lawler PR, McVerry BJ, Kim KS, Baumann Kreuziger L, Solomon SD, Kosiborod MN, Berry SM, Bochicchio GV, Contoli M, Farkouh ME, Froess JD, Gandotra S, Greenstein Y, Hade EM, Hanna N, Hudock K, Hyzy RC, Ibáñez Estéllez F, Iovine N, Khanna AK, Khatri P, Kirwan BA, Kutcher ME, Leifer E, Lim G, Lopes RD, Lopez-Sendon JL, Luther JF, Nigro Maia L, Quigley JG, Wahid L, Wilson JG, Zarychanski R, Kindzelski A, Geraci MW, Hochman JS, ACTIV-4a Investigators. Effect of P2Y12 Inhibitors on Organ Support-Free Survival in Critically Ill Patients Hospitalized for COVID-19: A Randomized Clinical Trial. JAMA Netw Open. 2023 05 01; 6(5):e2314428. View in PubMed
- Biffl WL, Ball CG, Moore EE, West M, Russo RM, Balogh Z, Kornblith L, Castelo M, WTA Multicenter Trials Group on Pancreatic Injuries. Current Use and Utility of MRCP, ERCP and Pancreatic Duct Stents: A Secondary Analysis from the WTA Multicenter Trials Group on Pancreatic Injuries. J Trauma Acute Care Surg. 2023 May 01. View in PubMed
- Kornblith LZ, Sadhanandhan B, Arun S, Long R, Johnson AJ, Noll J, Ramchand CN, Olynyk JK, Farrell DH. γ' fibrinogen levels as a biomarker of COVID-19 respiratory disease severity. Blood Cells Mol Dis. 2023 07; 101:102746. View in PubMed
- View All Publications
Books Chapters & Edited Books
- Diane A. Schwartz, Lucy Z. Kornblith, John B. Holcomb, Mitchell Jay Cohen. "Chapter 128. Multitrauma Derangement in Hemostasis and Thrombosis." In: Marder et al: Hemostasis and Thrombosis: Basic Principles and Clinical Practice, 6th eds. 2013
- Rochelle Dicker, Lucy Z. Kornblith. "Chapter 26. Acute Abdominal Pain." In: Vincent et al: Textbook of Critical Care, 7th eds. 2017
- Anamaria J. Robles, Lucy Z. Kornblith. "Coagulopathy in Trauma". In: Dynamed Plus, 2017 Zachary Matthay, Lucy Z. Kornblith. "Platelets." In: Trauma Induced Coagulopathy, 2nd eds. 2019
- Zachary Matthay, Lucy Z. Kornblith. "Platelet Contributions to Trauma Induced Coagulopathy: Updates in Post-injury Platelet Biology, Platelet Transfusions, and Emerging Platelet Based Hemostatic Agents." Hemostasis: Current Trauma Reports. 2019
- Zachary Matthay, Lucy Z. Kornblith. "Platelet Imaging." IntechOpen. http://mts.intechopen.com/articles/show/title/platelet-imaging. 2020
- Woon Cho Kim, Lucy Z. Kornblith "Injuries to the Liver and Biliary Tract." Blumgart's Surgery of the Liver, Biliary Tract and Pancreas, 7th Ed. 2020
- Zachary Matthay, Lucy Z. Kornblith. "Coagulopathy in Trauma". In: Dynamed Plus, 2020
- Lucy Z. Kornblith. "Doing Research at a University-Based Institution." Navigating Surgical Critical Care Fellowship Successfully and Beyond. Surgical Critical Care Fellow Handbook. November 2022
- Starr N, Matthay Z, Fields A, Neal M, Kornblith L. "Platelet Transfusion for Trauma Resuscitation." Current Trauma Reports. 2020
- David Efron, Matthew Benns, Lucy Kornblith. "Esophageal Emergencies." AAST/ESTES Emergency Surgery Course Handbook. 2022
- Kent Garber, Lucy Z. Kornblith. "Acute Respiratory Distress Syndrome." Clinical Scenarios in Surgery, 3rd Ed. 2023
View all
In the News
- UCSF Department of Surgery - May 19, 2023It is our pleasure to announce this year's recipients of the annual Holly Smith Award for Exceptional Service to the School of Medicine. Please join me in congratulating the recipents from the Department of Surgery: Lucy Zumwinkle Kornblith, MD Kalpana Harish, MPH The award, which recognizes exceptional service to the School of Medicine, is the school's most prestigious honor, and provides an opportunity to celebrate our colleagues who embody the qualities and contributions [...]
- UCSF Department of Surgery - November 15, 2022The Department of Surgery is excited to announce the appointment of Dr. Lucy Z. Kornblith as the Department's inaugural Director for Gender Equity! Lucy Zumwinkle Kornblith, M.D., is an Assistant Professor of Surgery and Laboratory Medicine at the University of California, San Francisco. Her clinical practice includes trauma surgery, surgical critical care, and acute care surgery. Dr. Kornblith received a Bachelor's degree in Molecular Biology from the University of California, Santa [...]
- UCSF Department of Surgery - September 07, 2022Muriel Steele Society's own co-chair, Dr. Lucy Kornblith, was nominated and selected as one of the Association of Women Surgeons Top 40 Under 40! This award recognizes outstanding women surgeons who are trailblazers in their field or who are making a significant impact with their actions. Congratulations, Dr. Kornblith!
- UCSF General Surgery Residency Program - - November 16, 2020Zachary Matthay, M.D., a general surgery research resident, received the basic science award at the Northern California Chapter of the American College of Surgeons Committee on Trauma Resident Research Competition, held virtually on October 21st, 2020. His presentation, titled "Leveraging the Catecholamine Response after Trauma: An Opportunity to Enhance Platelet Dependent Hemostasis?" examined the relationships between catecholamine surges after injury with platelet dependent hemostasis and [...]
- UCSF Department of Surgery at Zuckerberg San Francisco General - July 01, 2020UCSF Surgeon-scientist Lucy Kornblith, M.D. (PI) and her mentee, Zachary Matthay, M.D. (Co-PI) were awarded two grants for their proposed COVID-19-related research by the UCSF COVID-19 Rapid Response Pilot Grant Program, supported by the National Center for Advancing Translational Sciences, and National Institutes of Health (sponsored by the UCSF Academic Senate, Clinical and Translational Science Institute, and the Research Development Office). The first award will support their proposed [...]
- UCSF General Surgery Residency Program - - March 02, 2020Zachary Matthay, M.D., a general surgery research resident, received the prestigious Ernest E. Moore Basic Science Research Prize from the Western Trauma Association for his investigations and manuscript on "Dynamic Effects of In-Vivo and In-Vitro Calcium on Platelet Behavior". The award was given during the 50th Annual Western Trauma Association Meeting, held February 23-28, 2020 in Sun Valley, Idaho. He is the 2nd recipient of this award, which was developed to encourage and support basic [...]
- UCSF Department of Surgery at Zuckerberg San Francisco General - - December 12, 2019UCSF surgeon-scientist Lucy Zumwinkle Kornblith, MD is a co-investigator on a newly awarded $2M Department of Defense Congressionally Directed Medical Research Program in collaboration with the UCSF Department of Laboratory Medicine, and OHSU Division of Trauma, Critical Care, and Acute Care Surgery, for the study of "Freeze Dried Platelet Extracellular Vesicles as a Hemostatic Adjunct to Resuscitation for Prolonged Field Care." The DOD/CDMRP funded study is a multicenter, [...]
- UCSF Department of Surgery at Zuckerberg San Francisco General - - July 23, 2019Lucy Kornblith, M.D., Assistant Professor of Surgery in the UCSF Department of Surgery at ZSFG, is the 2019 recipient of The Irene Perstein Award for 2019, awarded by the UCSF School of Medicine to an outstanding, newly recruited, junior woman scientist. This unique award honors the legacy of Ms. Irene Perstein, who donated funds to support junior women faculty at UCSF. The highly competitive award is based on criteria including the novelty and innovation of the science, and the potential [...]
- Muriel Steele Society - - May 31, 2019We are pleased to announce that the Muriel Steele Society website has officially launched! The Muriel Steele Society (MSS) was established in honor of Muriel Steele, MD, the first woman surgeon at San Francisco General Hospital (SFGH) — now Zuckerberg San Fransisco General (ZSFG). Throughout her career, Dr. Steele experienced significant prejudice and overcame enormous obstacles on the road to becoming a phenomenal surgeon. MSS is an inclusive community dedicated to inspiring, supporting, and [...]
- UCSF Department of Surgery - - May 21, 2019We are pleased to announce the establishment of the Muriel Steele Society (MSS), founded in honor of Muriel Steele, MD, the first woman surgeon at San Francisco General Hospital (SFGH) — now Zuckerberg San Fransisco General (ZSFG). Dr. Steele experienced significant prejudice and overcame enormous obstacles on the road to becoming a phenomenal surgeon. Led by co-chairs, Mika Varma MD, Professor and Chief of Colorectal Surgery, and Lucy Kornblith MD Assistant Professor, ZSFG Trauma and Surgical [...]
- UCSF Department of Surgery - - March 08, 2019The Muriel Steele Society invites you to celebrate International Women's Day at UCSF by recognizing our fantastic women surgeons and supporting initiatives that help us achieve gender equity that enable all of us to excel. To stimulate frank discussions about gender parity, inclusion and diversity, we'd like to share the lecture of Joan Reede, MD, MS, MPH, MBA, delivered at the American College of Surgeons (ACS) Clinical Congress in 2018. Olga M. Jonasson, MD, Lecture: A path toward [...]
Lucy Kornblith, M.D. Recipient of 5-Year $1M NIH K23 Award for Study of Post-Injury Platelet Biology
UCSF Department of Surgery at Zuckerberg San Francisco General - - December 07, 2018UCSF trauma surgeon Lucy Kornblith, M.D. has been awarded a 5-Year $1M National Institutes of Health (NIH) K23, Mentored Patient-Oriented Research Award to study to post-injury platelet biology. The award, through the National Institute of General Medical Studies, will support Dr. Kornblith's research through 2023. The grant titled "Post-Injury Platelet Biology: Mechanisms and Outcomes", supports translational patient-oriented research. Specifically, Dr. Kornblith will investigate causal [...]
- Department of Surgery at Zuckerberg San Francisco General - December 05, 2018Trauma surgeons at Zuckerberg San Francisco General Hospital and Trauma Center have been among the strongest proponents for physicians speaking out on the issue of gun violence and conducting research to reduce suffering and prevent needless and tragic deaths. They have harnessed the power of Twitter in the service of community outreach and effecting social change. Notably, Rachael A. Callcut, M.D., MSPH was among the group that created the Twitter handle, @ThisIsOurLane and Andre Campbell, [...]
- UCSF Department of Surgery at Zuckerberg San Francisco General - - December 04, 2018The National Trauma Institute recently issued an update on the progress of CLOTT Study, a 2nd phase that will more closely investigate the role of platelet biology in post-traumatic pulmonary embolism. To that end, UCSF surgeon-scientist Lucy Kornblith, M.D. has been recruited by principal investigator M. Margaret "Peggy" Knudson, M.D., FACS. Following a productive investigation of the incidence of pulmonary thrombi after injury and the role of clot breakdown in the development of [...]
- Department of Surgery at ZSFG - - July 14, 2018Trauma Surgeon Lucy Kornblith, M.D. has been awarded the Eastern Association for the Surgery of Trauma (EAST) Trauma Research Scholarship to study post-injury platelet biology. Dr. Kornblith is a graduate of the UCSF General Surgery Residency Program and subsequently completed fellowships in Surgical Critical Care and Trauma Surgery, and Trauma and Emergency Care at UCSF. She will be joining the UCSF General Surgery Faculty August 1, 2018 and will be based at Zuckerberg San Francisco [...]
- UCSF Department of Surgery - - May 26, 2017Surgeons, from left, Lucy Kornblith, Rita Mukhtar and Carter Lebares pose for a photograph in the lobby of the UCSF Clinical Science Building in San Francisco, Calif., on Wednesday, April 19, 2017. (Courtesy Anda Chu/Bay Area News Group) The April 3, 2017 cover of the New Yorker depicting four women in blue doctors' scrubs over an operating table has gone viral. Reflecting the power of that image, female surgeons throughout the world have been posting group selfie photos of themselves [...]
- UCSF General Surgery Residency Program - April 01, 2014Lucy Kornblith, MD, a research fellow in the UCSF General Surgery Residency Program and member the Cohen Lab led by her research mentor, Mitchell J. Cohen, M.D., was recently awarded the Earl Young Award for 2014 from the Western Trauma Association. (Last year the award went to another UCSF General Surgery resident, Matt Kutcher, MD.) The Earl Young Award, the most prestigious for resident research in trauma, is the result of a highly competitive process to determine the top resident [...]
