Department of Surgery Clinical Trials

Listed below are UCSF clinical trials grouped by conditions and treatments that are applicable to UCSF Department of Surgery patients.  Trials are led by Principal Investigators from both the Department of Surgery, and other multidisciplinary programs at UCSF.  Each trial includes a biography of the Principal Investigator and contact information for patients interested in enrolling.

Anal Cancer

Cisplatin, Fluorouracil, Cetuximab, and Radiation Therapy in Treating Patients With HIV and Stage I, Stage II, or Stage III Anal Cancer
Study ID: AMC-045
Principal Investigator:
Andrew H. Ko, M.D.
Recruiting

Aortic Aneurysms

Bifurcated Stent-Graft for Endovascular Repair of Aneurysms Involving the Proximal Aortic Arch
Study ID: H9065-28979
Principal Investigator:
Timothy A. M. Chuter, M.D.
Recruiting
Endovascular Exclusion of Thoracoabdominal and/or Paravisceral Abdominal Aortic Aneurysm
Study ID: H5357-26067
Principal Investigator:
Linda M. Reilly, M.D.
Recruiting
Follow-up After Endovascular Repair of Abdominal Aortic Aneurysm
Study ID: H53537-26003
Principal Investigator:
Linda M. Reilly, M.D.
Recruiting
Hemodynamic Changes After Aortic Aneurysm Treatment With Stent-Graft
Study ID: H51821-27504
Principal Investigator:
Jade S. Hiramoto, M.D.
Recruiting
Prospective Aneurysm Trial: High Angle Aorfixâ„¢ Bifurcated Stent Graft
Study ID: H9065-29058
Principal Investigator:
Timothy A. M. Chuter, M.D.
Recruiting
Zenith(R) Fenestrated Abdominal Aortic Aneurysm (AAA) Endovascular Graft Clinical Study
Study ID: H9146-25242
Principal Investigator:
Darren Schneider, M.D.
Recruiting
Zenith(R) Low Profile AAA Endovascular Graft Clinical Study
Study ID: 08-013
Principal Investigator:
Linda M. Reilly, M.D.
Recruiting
Zenith(R) Low Profile AAA Endovascular Graft Clinical Study
Study ID: 08-013
Principal Investigator:
Linda M. Reilly, M.D.
Recruiting

Biliary Cancer (Bile Duct & Gallbladder)

Gemcitabine and Capecitabine to Treat Patients With Advanced Pancreatic and Biliary Cancers
Study ID: UCSF-074510
Principal Investigator:
Andrew H. Ko, M.D.
Recruiting

Carotid Artery Disease

A Carotid Stenting Boston Scientific Surveillance Program
Study ID: H9146-34330
Principal Investigator:
Darren Schneider, M.D.
Recruiting
SAPPHIRE -The Use of Stenting and Angioplasty for Treatment of Carotid Artery Disease
Study ID: H914631429
Principal Investigator:
Darren Schneider, M.D.
Recruiting

Colon Cancer

Cetuximab and/or Bevacizumab Combined With Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer
Study ID: CALGB-C80405
Principal Investigator:
Alan P. Venook, M.D.
Recruiting
Comparison of Combination Chemotherapy Regimens With or Without Cetuximab in Treating Patients Who Have Undergone Surgery For Stage III Colon Cancer
Study ID: CTSU NCCTG-N0147
Principal Investigator:
Alan P. Venook, M.D.
Recruiting

Constipation

Biofeedback Treatment for Functional Constipation
Study ID: RCTBF
Principal Investigator:
Madhulika Varma, M.D.
Completed
Biofeedback Treatment for Functional Constipation
Study ID: RCTBF
Principal Investigator:
Madhulika Varma, M.D.
Completed
Biofeedback Treatment for Functional Constipation
Study ID: RCTBF
Principal Investigator:
Madhulika Varma, M.D.
Completed

Esophageal Cancer

Chemotherapy & Erlotinib in Treating Patients w/ Esophageal or Gastroesophageal Cancer That Cannot Be Removed by Surgery
Study ID: UCSF-064511
Principal Investigator:
W. Michael Korn, MD
Recruiting

Fecal Incontinence

A Randomized, Blinded, Multicenter Study to Evaluate NASHA/Dx for the Treatment of Fecal Incontinence
Study ID: QMED
Principal Investigator:
Madhulika Varma, M.D.
Active, but not currently recruiting
A Randomized, Blinded, Multicenter Study to Evaluate NASHA/Dx for the Treatment of Fecal Incontinence
Study ID: QMED
Principal Investigator:
Madhulika Varma, M.D.
Active, but not currently recruiting

Gastric Cancer

A Study of Telatinib in Combination With Chemotherapy in Subjects With Advanced Gastric Cancer
Study ID: TEL0805
Principal Investigator:
Andrew H. Ko, M.D.
Recruiting
A Study of Telatinib in Combination With Chemotherapy in Subjects With Advanced Gastric Cancer
Study ID: TEL0805
Principal Investigator:
Andrew H. Ko, M.D.
Recruiting

Islet Cell Transplant

Islet Transplantation in Type 1 Diabetes
Study ID: DAIT CIT-07
Principal Investigator:
Andrew M. Posselt, M.D., Ph.D.
Recruiting
Islet Transplantation in Type 1 Diabetes
Study ID: DAIT CIT-07
Principal Investigator:
Andrew M. Posselt, M.D., Ph.D.
Recruiting
Peritransplant Deoxyspergualin in Islet Transplantation in Type 1 Diabetes
Study ID: DAIT CIT-03
Principal Investigator:
Andrew M. Posselt, M.D., Ph.D.
Recruiting
Peritransplant Deoxyspergualin in Islet Transplantation in Type 1 Diabetes
Study ID: DAIT CIT-03
Principal Investigator:
Andrew M. Posselt, M.D., Ph.D.
Recruiting
Peritransplant Deoxyspergualin in Islet Transplantation in Type 1 Diabetes
Study ID: DAIT CIT-03
Principal Investigator:
Andrew M. Posselt, M.D., Ph.D.
Recruiting
Peritransplant Deoxyspergualin in Islet Transplantation in Type 1 Diabetes
Study ID: DAIT CIT-03
Principal Investigator:
Andrew M. Posselt, M.D., Ph.D.
Recruiting

Kidney Transplant

A Dose Escalation and Safety Study of I5NP to Prevent Delayed Graft Function in Patients Undergoing Deceased Donor Kidney Transplantation, Part A
Study ID: QRK.006 (Quark)
Principal Investigator:
Sandy Feng, M.D., Ph.D.
Recruiting
A Phase II Study of Belatacept (BMS-224818) With a Steroid-free Regimen in Subjects Undergoing Kidney Transplantation
Study ID: IM103034
Principal Investigator:
Flavio Vincenti, M.D.
Active, but closed to enrollment
A Study of BMS-224818 (Belatacept) in Patients Who Have Undergone a Kidney Transplant and Are Currently on Stable Cyclosporine or Tacrolimus Regimen With or Without Corticosteroids
Study ID: IM103010
Principal Investigator:
Flavio Vincenti, M.D.
Active, but closed to enrollment
Cidofovir in Renal Transplant Recipients With BKVN
Study ID: CASG209
Principal Investigator:
Stephen J. Tomlanovich, M.D.
Recruiting
Cidofovir in Renal Transplant Recipients With BKVN
Study ID: CASG209
Principal Investigator:
Stephen J. Tomlanovich, M.D.
Recruiting
Cidofovir in Renal Transplant Recipients With BKVN
Study ID: CASG209
Principal Investigator:
Stephen J. Tomlanovich, M.D.
Recruiting
Cidofovir in Renal Transplant Recipients With BKVN
Study ID: CASG209
Principal Investigator:
Stephen J. Tomlanovich, M.D.
Recruiting
Cidofovir in Renal Transplant Recipients With BKVN
Study ID: 04-047
Principal Investigator:
Flavio Vincenti, M.D.
Recruiting
Cidofovir in Renal Transplant Recipients With BKVN
Study ID: 04-047
Principal Investigator:
Flavio Vincenti, M.D.
Recruiting
Extension Study Of Subjects From Study A3921030 For The Prevention Of Acute Rejection In Kidney Transplant Patients
Study ID: A3921050 LTE
Principal Investigator:
Flavio Vincenti, M.D.
Active, but closed to enrollment
Extension Study Of Subjects From Study A3921030 For The Prevention Of Acute Rejection In Kidney Transplant Patients
Study ID: A3921050 LTE
Principal Investigator:
Flavio Vincenti, M.D.
Active, but closed to enrollment
Extension Study Of Subjects From Study A3921030 For The Prevention Of Acute Rejection In Kidney Transplant Patients
Study ID: A3921050 LTE
Principal Investigator:
Flavio Vincenti, M.D.
Active, but closed to enrollment
Kidney and Liver Transplantation in People With HIV
Study ID: 1U01AI052748 (HIVTR)
Principal Investigator:
Peter Stock M.D., Ph.D
Recruiting
Kidney and Liver Transplantation in People With HIV
Study ID: 1U01AI052748 (HIVTR)
Principal Investigator:
Peter Stock M.D., Ph.D
Recruiting
Kidney and Liver Transplantation in People With HIV
Study ID: 1U01AI052748 (HIVTR)
Principal Investigator:
Peter Stock M.D., Ph.D
Recruiting
Kidney and Liver Transplantation in People With HIV
Study ID: 1U01AI052748 (HIVTR)
Principal Investigator:
Peter Stock M.D., Ph.D
Recruiting
Kidney and Liver Transplantation in People With HIV
Study ID: 1U01AI052748 (HIVTR)
Principal Investigator:
Peter Stock M.D., Ph.D
Recruiting
Rituximab in Kidney Transplantation
Study ID: CTOT-02
Principal Investigator:
Flavio Vincenti, M.D.
Recruiting
Rituximab in Kidney Transplantation
Study ID: CTOT-02
Principal Investigator:
Flavio Vincenti, M.D.
Recruiting
Rituximab in Kidney Transplantation
Study ID: CTOT-02
Principal Investigator:
Flavio Vincenti, M.D.
Recruiting
Study Comparing the Safety and Efficacy of BMS-224818 to Cyclosporine, in Patients Receiving a Kidney Transplant, When Used in Combination With CellCept, Simulect, and Corticosteroids.
Study ID: IM13100
Principal Investigator:
Flavio Vincenti, M.D.
Active, but closed to enrollment
Study of 2 Dose Levels of a JAK3 Inhibitor for the Prevention of Acute Rejection in Kidney Transplant Patients
Study ID: A3921021
Principal Investigator:
Flavio Vincenti, M.D.
Active, but closed to enrollment
Study of Belatacept in Subjects Who Are Undergoing a Renal Transplant
Study ID: Benefit-Ext
Principal Investigator:
Flavio Vincenti, M.D.
Active, but closed to enrollment

Kidney-Focal Segmental Glomerulosclerosis

Safety Study of GC1008 in Patients With Focal Segmental Glomerulosclerosis (FSGS) of Single Doses of GC1008 in Patients With Treatment Resistant Idiopathic FSGS
Study ID: GC1008FSGS00505
Principal Investigator:
Flavio Vincenti, M.D.
Active, but closed to enrollment

Liver Transplant

Efficacy and Safety of Concentration-controlled Everolimus to Eliminate or to Reduce Tacrolimus Compared to Tacrolimus in de Novo Liver Transplant Recipients
Study ID: CRAD001H2304 (RAD)
Principal Investigator:
Sandy Feng, M.D., Ph.D.
Recruiting
Kidney and Liver Transplantation in People With HIV
Study ID: 1U01AI052748 (HIVTR)
Principal Investigator:
Peter Stock M.D., Ph.D
Recruiting
Kidney and Liver Transplantation in People With HIV
Study ID: 1U01AI052748 (HIVTR)
Principal Investigator:
Peter Stock M.D., Ph.D
Recruiting
Kidney and Liver Transplantation in People With HIV
Study ID: 1U01AI052748 (HIVTR)
Principal Investigator:
Peter Stock M.D., Ph.D
Recruiting
Kidney and Liver Transplantation in People With HIV
Study ID: 1U01AI052748 (HIVTR)
Principal Investigator:
Peter Stock M.D., Ph.D
Recruiting
Kidney and Liver Transplantation in People With HIV
Study ID: 1U01AI052748 (HIVTR)
Principal Investigator:
Peter Stock M.D., Ph.D
Recruiting
The Effect of Rituximab on the Development of Anti-Donor Antibodies
Study ID: GNE Rituxin
Principal Investigator:
Flavio Vincenti, M.D.
Recruiting
The Effect of Rituximab on the Development of Anti-Donor Antibodies
Study ID: GNE Rituxin
Principal Investigator:
Flavio Vincenti, M.D.
Recruiting
The Effect of Rituximab on the Development of Anti-Donor Antibodies
Study ID: GNE Rituxin
Principal Investigator:
Flavio Vincenti, M.D.
Recruiting

Lung Transplant

Study of EZ-2053 in the Prophylaxis of Acute Pulmonary Allograft Rejection
Study ID: EZ-2053-001
Principal Investigator:
Charles Hoopes, M.D.
Recruiting

Mesothelioma

An Efficacy Study of MORAb-009 in Subjects With Pleural Mesothelioma
Study ID: UCSF-08656
Principal Investigator:
Thierry Jahan, MD
Recruiting
Dasatinib in Treating Patients With Previously Treated Malignant Mesothelioma
Study ID: CALGB-30601
Principal Investigator:
Sarita Dubey, MD
Active, but not currently recruiting

Neuroendocrine Tumors

Combination Chemotherapy and Bevacizumab in Treating Patients With Advanced Neuroendocrine Tumors
Study ID: UCSF-04458
Principal Investigator:
Emily Bergsland, M.D.
Recruiting
RAD001 and Erlotinib in Patients With Neuroendocrine Tumors
Study ID: UCSF-084511
Principal Investigator:
Emily Bergsland, M.D.
Recruiting

Non-Small Cell Lung Cancer

A First-line Study of IMC-1121B With Paclitaxel and Carboplatin in Stage IIIB/IV Non-small Cell Lung Cancer
Study ID: UCSF-08653
Principal Investigator:
Sarita Dubey, MD
Recruiting
High-Dose or Standard-Dose Radiation Therapy and Chemotherapy in Treating Patients With Newly Diagnosed Stage III Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery
Study ID: RTOG-0617
Principal Investigator:
Mack Roach III M.D., F.A.C.R.
Recruiting
PF-00299804 As a Single Oral Agent In Untreated Adenocarcinoma Of The Lung In Non-Smokers Or Former Light Smokers
Study ID: A7471017
Principal Investigator:
Sarita Dubey, MD
Recruiting
RADIANT: A Study of Tarceva After Surgery With or Without Adjuvant Chemotherapy in NSCLC Patients Who Have EGFR-positive Tumors
Study ID: OSI-774-302
Principal Investigator:
Sarita Dubey, MD
Recruiting

Obesity

Insulin Sensitivity after Gastric Bypass, Adjustable Gastric Banding and Caloric Restriction in Persons With Morbid Obesity: A Stratified, Randomized, Controlled Pilot Trial.
Study ID: UCSF-H49493-28734
Principal Investigator:
Guilherme Campos, M.D., Ph.D.
Active, but not currently recruiting
Transoral Gastroplasty for the Treatment of Morbid Obesity
Study ID: S107
Principal Investigator:
Stanley J. Rogers, M.D.
Active, but not currently recruiting

Pancreatic Cancer

Gemcitabine and Capecitabine to Treat Patients With Advanced Pancreatic and Biliary Cancers
Study ID: UCSF-074510
Principal Investigator:
Andrew H. Ko, M.D.
Recruiting
Gemcitabine and S-1 for Locally Advanced Unresectable or Metastatic Pancreatic Cancer
Study ID: UCSF-06456
Principal Investigator:
Andrew H. Ko, M.D.
Recruiting
Study of PEP02 as a Second Line Therapy for Metastatic Pancreatic Cancer
Study ID: PEP0208
Principal Investigator:
Andrew H. Ko, M.D.
Active, but not currently recruiting

Peripheral Artery Disease

Endothelial Function and Vein Graft Remodeling
Study ID: H63794-33476
Principal Investigator:
Christopher D. Owens, M.D., MSc
Recruiting
Multifactor Risk Reduction for Optimal Management of PAD
Study ID: 5RO1NR9197-2
Principal Investigator:
Roberta K. Oka, A.N.P., D.NSc.
Recruiting
Use of Vascular Repair Cells (VRC) in Patients With Peripheral Arterial Disease to Treat Critical Limb Ischemia
Study ID: H9146-31071
Principal Investigator:
Darren Schneider, M.D.
Recruiting

Rectal Cancer

Cetuximab and/or Bevacizumab Combined With Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer
Study ID: CALGB-C80405
Principal Investigator:
Alan P. Venook, M.D.
Recruiting
Radiation Therapy and Fluorouracil With or Without Combination Chemotherapy Followed by Surgery in Treating Patients With Stage II or Stage III Rectal Cancer
Study ID: UCSF-03451
Principal Investigator:
Madhulika Varma, M.D.
Recruiting

Small Cell Lung Cancer

Sunitinib, Cisplatin or Carboplatin, and Etoposide in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Study ID: CALGB-30504
Principal Investigator:
Sarita Dubey, MD
Active, but not currently recruiting

Solid Tumor

A Phase 1 Dose-escalation Study of a Cell Cycle Inhibitor With and Without Gemcitabine in Patients With Solid Tumors or Lymphoma (Study P05248AM2)
Study ID: UCSF-08991
Principal Investigator:
Adil Daud, M.D.
Recruiting
A Study of R1507 in Combination With Multiple Standard Chemotherapy Treatments in Patients With Advanced Solid Tumors
Study ID: UCSF-08994
Principal Investigator:
Pamela Munster, M.D.
Recruiting
Imatinib Mesylate, Bevacizumab, and Cyclophosphamide in Treating Patients With Refractory Metastatic Solid Tumors
Study ID: UCSF-06991
Principal Investigator:
Emily Bergsland, M.D.
Suspended
Panobinostat and Epirubicin in Treating Patients With Metastatic Malignant Solid Tumors
Study ID: UCSF-09991
Principal Investigator:
Pamela Munster, M.D.
Recruiting

Thoracic Aneurysms

A Clinical Study of the Safety and Efficacy of the Relay Thoracic Stent-Graft in Patients With Thoracic Aortic Pathologies
Study ID: H9065-30421
Principal Investigator:
Timothy A.M. Chuter, M.D.
Recruiting
Endovascular Exclusion of Thoracoabdominal and/or Paravisceral Abdominal Aortic Aneurysm
Study ID: H5357-26067
Principal Investigator:
Linda M. Reilly, M.D.
Recruiting
Evaluation of the GORE TAG Thoracic Endoprosthesis in the Treatment of Aneurysms
Study ID: H9146-28715
Principal Investigator:
Darren Schneider, M.D.
Active, but closed to enrollment
STARZ-TX2 Clinical Study: Study of Thoracic Aortic Aneurysm Repair With the Zenith TX2 Endovascular Graft
Study ID: 03-536
Principal Investigator:
Darren Schneider, M.D.
Active, but closed to enrollment
STARZ-TX2 Clinical Study: Study of Thoracic Aortic Aneurysm Repair With the Zenith TX2 Endovascular Graft
Study ID: 03-536
Principal Investigator:
Darren Schneider, M.D.
Active, but closed to enrollment