- 1864-1880 Founding Chairman Hugh H. Toland
- 1880-1899 Robert A. McLean, M.D.
- 1899-1912 Thomas W. Huntington, M.D.
- 1912-1929 Wallace I. Terry, M.D.
- 1929-1947 Howard C. Naffziger, M.D.
- 1947-1956 H. Glenn Bell, M.D.
- 1956-1963 Leon Goldman, M.D.
- 1964-1975 J. Englebert Dunphy, M.D.
- 1975-1985 Paul Ebert, M.D.
- 1987-1993 Haile T. Debas, M.D.
- 1993-1999 Theodore R. Schrock, M.D.
