Children with a rare, life-threatening disease that is the most common cause of neonatal liver failure - biliary atresia - better tolerate liver transplants from their mothers than from their fathers, according to a UCSF-led study......"This result is exciting because it supports the concept that trafficking of cells between the mother and the fetus has functional significance long after the pregnancy is over," said senior author Tippi MacKenzie, M.D., assistant professor of pediatric surgery at UCSF and a fetal surgeon at UCSF Benioff Children's Hospital. "This is a topic we are actively [...]
On November 5th, Captain Chesley B. "Sully" Sullenberger, III spoke to a UCSF audience at Cole Hall on "Leadership in Advancing National Efforts in Patient Safety and Optimal Quality of Care". He was introduced by Hobart W. Harris, M.D., M.P.H., Chief of the Division of General Surgery, who underscored how Sullenberger's aviation experience has informed patient safety and the evolution of modern clinical practice.Captain Sullenberger spoke at the invitation of Nancy L. Ascher, M.D., Ph.D., Chair of UCSF Department of Surgery.
Drawing on his 43-year career as a pilot and safety [...]
UCSF Adult Cardiothoracic Surgery -November 08, 2012
"Jimenez went to UCSF's Lung Transplant Program, one of the top programs in the country, according to the latest Scientific Registry of Transplant Recipients. UCSF is among three out of 70 programs for "higher than expected" outcomes based on complex risk factors.
The success of the program is multifactorial and a multidisciplinary effort that starts with excellent anesthetic management, meticulous surgical technique and perioperative surgical care, and long-term close surveillance," said Jasleen Kukreja, MD, MPH, program and surgical director of the UCSF Lung Transplant Program."
Michael R. Harrison, MD, founder and director emeritus of the Fetal Treatment Center at the UCSF Benioff Children's Hospital, was recognized last week for his contributions to life-saving fetal surgery with the Ronald McDonald House Charities Medical Award of Excellence.
Building on their earlier work reported in The Lancet, two UCSF thoracic surgeons David M. Jablons, M.D. (left) and Michael Mann, M.D. (middle), and Johannes Kratz, M.D. (right) a former surgical resident in the Thoracic Oncology Lab, showed they could accurately stratify patients even with the earliest stage of lung cancer into groups at low-, intermediate- or high-risk of death based solely on the activity of 14 different genes found in their tumors. The group analyzed lung tumors of patients diagnosed as Stage 1A (T1a node-negative non-small-cell lung cancers (NSCLC)), the [...]
The Nathan Bass UCSF Liver Transplant Conference 2012 will take place November 16-17th in Napa, CA. The Annual Conference at The Siverado in Napa features an outstanding group of faculty led by Francis Y.K. Yao, M.D. and is one of the most important educational activities of the Liver Transplant Service. It is an intense interactive educational program starting Friday afternoon through Saturday afternoon. The program provides up-to-date evidence-based information to regional gastroenterologists/hepatologists and healthcare professionals involved in pre- and post-transplant of the liver as [...]
The NIH has awarded two UCF scientists, Hassan Lemjabbar-Alaoui, Ph.D and Joanna J. Phillips, M.D., Ph.D., a five-year $2.2m grant to study the clinical utility of extracellular heparan sulfate endosulfatases, or SULFs, as biomarkers for early detection of non-small cell lung cancer (NSCLC) and malignant astrocytoma. Lung cancer is the leading cause of cancer death in the U.S. and world-wide. Astrocytomas are primary brain neoplasms (tumors). Glioblastoma multiforme (GBM), the most common and malignant primary brain tumor, was responsible for the death of the late Senator Edward M. Kennedy. [...]
This issue of Inside Surgery describes several exciting developments that are advancing our ability to provide outstanding care for a range of patients including the new Hepatobiliary Service, under the direction of Carlos Corvera, M.D., which provides comprehensive, multidisciplinary care for patients with liver and bile duct disease. Other topics include updates on Endocrine Surgery, San Fancisco General Hospital's Wraparound Project, and notable rankings of our surgeons within U.S. News & World Report annual update.
Surgeons at the UCSF Benioff Children's Hospital in San Francisco are using magnets to reshape the breastbones of children who suffer from Sunken Chest Syndrome. The technique is undergoing phase 3 clinical trials, but the doctors hope to prove that long term magnetic force is as effective and less painful than conventional surgery.
The Society of Clinical Trials has named UCSF's Management of Myelomeningocele Study (MOMS), a review of prenatal versus postnatal surgery for myelomengingocele (spina bifida), as its Trial of the Year. The study earned recognition as an important clinical trial that overcame difficulties and produced remarkable results.
UCSF Vascular & Endovascular Surgery -August 08, 2012
UCSF News reports on the link between depression and increased risk of peripheral artery disease (PAD) in a study conducted at the San Francisco VA Medical Center. The Heart and Soul Study research team was led by UCSF vascular surgeon Marlene Grenon, M.D., C.M. and included faculty at both UCSF Medical Center and the San Francisco VA.
Depression was linked with an increased risk of peripheral artery disease (PAD) in a study of more than 1,000 men and women with heart disease conducted by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.
On Saturday, August 11, 2012, UCSF will hold its annual Pediatric Transplant Picnic at McNears Beach in San Rafael, CA. We expect hundreds of children and their families will attend this yearly celebration of the Transplant Service at UCSF. An Olympic-themed party has been planned to include a costume contest with prizes, music, dancing, kayaking, face-painting, pinatas, and more. Barbeque fare and drinks will be provided and guests are encouraged to bring potluck dishes corresponding with the first letter of their last name: snacks (A-G), veggies (H-P) and fruit (Q-Z).
A new method for repairing Pectus Exacavatum using magnets and an external brace, developed by Michael Harrison, a pediatric surgeon at the University of California, San Francisco's Benioff Children's Hospital, could provide an alternative to the surgery.
Intrahepatic bile duct cancer, a rare and deadly form of cancer, known formally as cholangiocarcinoma, has been assumed to derive from cells in the bile ducts of the liver. However, an international team, led by Holger F. Willenbring, M.D., Ph.D., Associate Professor of Developmental and Stem Cell Biology in the Division of Transplant Surgery, Xin Chen, Ph.D.,and other prominent researchers, has shown that the disease actually may develop when hepatocytes, the most common type of liver cell, are transformed into intrahepatic cholangiocarcinoma cells or (ICCs), a process scientists [...]
Justin is being treated at the UCSF Comprehensive Center for Chest Wall Deformities, a new interdisciplinary pediatric clinic at UCSF Benioff Children's Hospital that offers a wide range of interventions for children with all types of chest wall deformities, from common to complex. Justin has the most common chest wall deformity called pectus excavatum, a congenital disorder which causes the chest to have a sunken or "caved in" appearance.
UCSF General Surgery Residency Program -June 21, 2012
Dr. Amar Nijagal was awarded the M. Judah Folkman Memorial Award by the American Pediatric Surgical Association at the 2012 APSA Annual meeting for his work entitled "Fetal Intervention Triggers the Activation of Paternal Antigen-Specific Maternal T Cells." Dr. Nijagal is currently a General Surgery resident at UCSF and has worked in Dr. Tippi MacKenzie's laboratory in the UCSF Division of Pediatric Surgery for the past three years. In 2011, he was also awarded the M. Judah Folkman Memorial Award for his presentation on "The Maternal Adaptive Immune Response Against Paternal Antigens Incites [...]
Liver cancer patients in need of an organ transplant often face a cruel reality -- while waiting for a deceased-donor liver, their cancer may worsen, spreading to other organs and making them ineligible for a transplant. With two children to raise and time ticking down, Amy Baghdadi was fast running out of options. But at her daughter's soccer practice, a fellow parent, who happened to be UCSF transplant surgeon, Andrew Posselt, M.D., Ph.D., heard Amy's story, and convinced there were other options to explore, referred her to the UCSF Liver Transplant Center. Then, a life-changing gift from [...]
In July 2011, the Department of Surgery created a new Hepatobiliary and Pancreas Service naming Carlos Corvera M.D., a hepatobiliary surgical oncologist, as its Chief. The multidisciplinary program brings together faculty members from surgery, hepatology, medical oncology, anesthesia, radiology and pathology to care for patients with benign and malignant conditions of the liver, gallbladder, biliary tract and pancreas. The service holds clinics and weekly tumor boards at the Mt. Zion and Parnassus campuses of UCSF.
"Rather than isolated silos of care, we have a team approach, which makes [...]