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Dr. Christopher Owens received his undergraduate and medical degree from Indiana University. He went on to complete a general surgery residency and vascular surgery fellowship at Brigham and Women's Hospital in Boston, MA. In addition, he completed a clinical fellowship in vascular medicine and endovascular surgery from St. Elizabeth Medical Center in Boston, MA.
Dr. Owens' clinical interests include peripheral artery disease (PAD), thoracic and abdominal aortic aneurysms, carotid artery disease, and dialysis access procedues. He is particularly interested in lower extremity limb revascularization for patients with PAD and critical limb ischemia (CLI).
Dr. Owens' research is focused on exploring novel drugs or biologics designed to prevent vein graft failure and restenosis after angioplasty and stenting. He is pursuing a better understanding of the factors that modify vein graft remodeling to the arterial environment, and a better appreciation of adaptive physiology and healing kinetics. Dr. Owens hopes to gain insights into the temporal sequence of the physiological, biomechanical and biochemical challenges during veing graft healing. He is currently the PI of an NIH-funded research project studying endothelial function and vein graft remodeling.
Warren Gasper, M.D., junior fellow in the Division of Vascular and Endovascular Surgery and a member of the research lab of Christopher Owens M.D., was awarded first prize in the poster competition at the annual meeting of the Society for Vascular Surgery (SVS) for the poster Percutaneous Peri-Adventitial Guanethidine Delivery Induces Renal Artery Sympathectomy: Preclinical Experience and Implication for Refractory Hypertension. One hundred researchers competed worldwide for the honor. The President and President-Elect of SVS, and an audience of vascular surgeons, choose the winner after viewing PowerPoint presentations from the ten finalists.
Peripheral artery disease (PAD) affects 10-12 million Americans and causes significant pain and disability. PAD occurs when there is a chronic buildup of fatty plaque within the arterial wall that restricts blood flow to the extremities (legs and feet). A new study led by Christopher Owens, M.D., Assistant Professor in the Division of Vascular and Endovascular Surgery, is investigating a new endovascular surgical intervention to prevent the "re-narrowing" of leg arteries following a prior surgery for PAD. This study, enrolling at both UCSF Medical Center and SFVAMC, integrates a medical device and drug that have each been FDA approved. The device - the Bullfrog® Micro-Infusion Catheter from Mercator MedSystems in San Leandro, Calif. - can precisely deliver drugs into the inflamed tissues (the adventitia and perivascular tissues) that surround diseased and damaged arteries.The study has just reached an important milestone with the enrollment of five patients.