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Department of Surgery »  Faculty »  Qizhi Tang, Ph.D.

Qizhi Tang, Ph.D.

Associate Professor of Surgery
Division of Transplant Surgery
Director, Transplantation Research Laboratory

Contact Information

(415) 476-1739
(415) 476-0789
(415) 502-8326 Fax
Qizhi.Tang@ucsfmedctr.org
   

Education

  • Peking Union Medical College, China, B.S., Medicine, 1984-89
  • University of South Alabama, M.S., Microbiology, 1989-91
  • University of Illinois at Chicago, Ph.D., Immunology, 1991-96

Postdoctoral Training

  • University of Illinois, Chicago, Postdoctoral Fellow, Immunology, 1996-98
  • University Of Chicago, Postdoctoral Fellow, Immunology, 1998-00
  • University of California, San Francisco, California, Postdoctoral Fellow, Immunology, 2000-02

Research Interests

  • Autoimmunity
  • Immune Tolerance
  • Immunotherapy
  • Islets of Langerhans Transplantation
  • Suppressor-Effector
  • T-Lymphocyte Subsets
  • T-Lymphocytes
  • Transplantation Immunology
  • Transplantation Tolerance

Biography

Dr. Tang received her bachelor's degree at Peking Union Medical College in China. She completed her graduate education in the US, getting her master's degree from the University of South Alabama and her PhD from the University of Illinois at Chicago. She completed post doctoral fellowships at the University of Illinois at Chicago and under renowned immunologist Dr. Jeffrey Bluestone at the University of Chicago and the University of California, San Francisco.

Dr. Tang joined the staff at the University of California, San Francisco in 2002 as an Assistant Professor of Pathology in the Diabetes Center where she focused on immune tolerance. She joined the transplantation department in 2007 to lead basic research on transplant immunology. She now focuses on regulatory T cell biology. She is one of the first to grow regulatory T cells and apply these cells in experimental therapy.

In addition to Dr. Tang's research duties, she has presented several national lectures. She has also published dozens of articles in the field of immunology.

 

Publications

Most recent publications from a total of 40
  1. Lee K, Nguyen V, Lee KM, Kang SM, Tang Q. Attenuation of donor-reactive T cells allows effective control of allograft rejection using regulatory T cell therapy. Am J Transplant. 2014 Jan; 14(1):27-38. View in PubMed
  2. Tang Q, Bluestone JA. Regulatory T-cell therapy in transplantation: moving to the clinic. Cold Spring Harb Perspect Med. 2013 Nov; 3(11). View in PubMed
  3. Putnam AL, Safinia N, Medvec A, Laszkowska M, Wray M, Mintz MA, Trotta E, Szot GL, Liu W, Lares A, Lee K, Laing A, Lechler RI, Riley JL, Bluestone JA, Lombardi G, Tang Q. Clinical grade manufacturing of human alloantigen-reactive regulatory T cells for use in transplantation. Am J Transplant. 2013 Nov; 13(11):3010-20. View in PubMed
  4. Nijagal A, Derderian C, Le T, Jarvis E, Nguyen L, Tang Q, Mackenzie TC. Direct and indirect antigen presentation lead to deletion of donor-specific T cells after in utero hematopoietic cell transplantation in mice. Blood. 2013 May 30; 121(22):4595-602. View in PubMed
  5. Tang Q, Leung J, Melli K, Lay K, Chuu EL, Liu W, Bluestone JA, Kang SM, Peddi VR, Vincenti F. Altered balance between effector T cells and FOXP3+ HELIOS+ regulatory T cells after thymoglobulin induction in kidney transplant recipients. Transpl Int. 2012 Dec; 25(12):1257-67. View in PubMed
  6. Lerner AG, Upton JP, Praveen PV, Ghosh R, Nakagawa Y, Igbaria A, Shen S, Nguyen V, Backes BJ, Heiman M, Heintz N, Greengard P, Hui S, Tang Q, Trusina A, Oakes SA, Papa FR. IRE1a induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. Cell Metab. 2012 Aug 8; 16(2):250-64. View in PubMed
  7. Tang Q, Lee K. Regulatory T-cell therapy for transplantation: how many cells do we need? Curr Opin Organ Transplant. 2012 Aug; 17(4):349-54. View in PubMed
  8. Nijagal A, Fleck S, Hills NK, Feng S, Tang Q, Kang SM, Rosenthal P, MacKenzie TC. Decreased risk of graft failure with maternal liver transplantation in patients with biliary atresia. Am J Transplant. 2012 Feb; 12(2):409-19. View in PubMed
  9. Tang Q, Bluestone JA, Kang SM. CD4(+)Foxp3(+) regulatory T cell therapy in transplantation. J Mol Cell Biol. 2012 Feb; 4(1):11-21. View in PubMed
  10. Scapini P, Lamagna C, Hu Y, Lee K, Tang Q, DeFranco AL, Lowell CA. B cell-derived IL-10 suppresses inflammatory disease in Lyn-deficient mice. Proc Natl Acad Sci U S A. 2011 Oct 11; 108(41):E823-32. View in PubMed
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