Department of Surgery »  Faculty »  Andrew M. Posselt, M.D., Ph.D.

Andrew M. Posselt, M.D., Ph.D., FACS

Professor of Surgery
Division of Transplant Surgery
Director, Pancreatic Islet Transplant Program

Contact Information

Academic Office
(415) 514-5606
andrew.posselt@ucsf.edu
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  • Stanford University, B.S., Biology, 1981-85
  • University of Pennsylvania, M.D., Medicine, 1985-93
  • University of Pennsylvania, Ph.D., Immunology, 1989-93
  • University of California, San Francisco, Resident, Medicine, 1993-96
  • University of California, San Francisco, Resident, Surgery, 1996-00
  • University of California, San Francisco, Fellow, Transplant Surgery, 2000-02
  • American Board of Internal Medicine, 1996
  • American Board of Surgery, 2002
  • Pancreatic Islet Transplantation Program
  • Bariatric Surgery Center
  • ABO-Incompatible Kidney Transplant Program
  • Assessment of long-term clinical outcomes in kidney donors
  • Clinical outcomes of bariatric surgery in patients with end-stage kidney or liver disease
  • Metabolic and biochemical consequences of bariatric surgery
  • Transplantation of pancreatic islets as treatment for type 1 diabetes mellitus

Dr. Andrew Posselt is an attending multi-organ transplant surgeon at UCSF and Director of the ABO-Incompatible Kidney Transplant Program as well as Co-director of the Pancreatic Islet Transplant Program and the Bariatric Surgery Program.  Dr. Posselt specializes in adult and pediatric kidney, liver and pancreas transplantation; laparoscopic donor nephrectomy; and laparoscopic as well as open bariatric surgery.  Dr. Posselt's current research interests include: 1) transplantation of pancreatic islets for the treatment of type 1 diabetes mellitus; 2) assessment of long-term renal function in kidney donors after donor nephrectomy; 3) immunologic and tolerogenic properties of embryonic stem cells; and 4) bariatric surgery in patients awaiting transplant. 

 
Most recent publications from a total of 75
  1. Kasiske BL, Kumar R, Kimmel PL, Pesavento TE, Kalil RS, Kraus ES, Rabb H, Posselt AM, Anderson-Haag TL, Steffes MW, Israni AK, Snyder JJ, Singh RJ, Weir MR. Abnormalities in biomarkers of mineral and bone metabolism in kidney donors. Kidney Int. 2016 Oct; 90(4):861-8. View in PubMed
  2. Hering BJ, Clarke WR, Bridges ND, Eggerman TL, Alejandro R, Bellin MD, Chaloner K, Czarniecki CW, Goldstein JS, Hunsicker LG, Kaufman DB, Korsgren O, Larsen CP, Luo X, Markmann JF, Naji A, Oberholzer J, Posselt AM, Rickels MR, Ricordi C, Robien MA, Senior PA, Shapiro AM, Stock PG, Turgeon NA. Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia. Diabetes Care. 2016 Jul; 39(7):1230-40. View in PubMed
  3. Song S, Faleo G, Yeung R, Kant R, Posselt AM, Desai TA, Tang Q, Roy S. Silicon nanopore membrane (SNM) for islet encapsulation and immunoisolation under convective transport. Sci Rep. 2016; 6:23679. View in PubMed
  4. McEnhill ME, Brennan JL, Winnicki E, Lee MM, Tavakol M, Posselt AM, Stock PG, Portale AA. Effect of Immigration Status on Outcomes in Pediatric Kidney Transplant Recipients. Am J Transplant. 2016 Jun; 16(6):1827-33. View in PubMed
  5. Wang LJ, Kin T, O'Gorman D, Shapiro AM, Naziruddin B, Takita M, Levy MF, Posselt AM, Szot GL, Savari O, Barbaro B, McGarrigle J, Yeh CC, Oberholzer J, Lei J, Chen T, Lian M, Markmann JF, Alvarez A, Linetsky E, Ricordi C, Balamurugan AN, Loganathan G, Wilhelm JJ, Hering BJ, Bottino R, Trucco M, Liu C, Min Z, Li Y, Naji A, Fernandez LA, Ziemelis M, Danobeitia JS, Millis JM, Witkowski P. A Multicenter Study: North American Islet Donor Score in Donor Pancreas Selection for Human Islet Isolation for Transplantation. Cell Transplant. 2016; 25(8):1515-23. View in PubMed
  6. Usatin DJ, Perito ER, Posselt AM, Rosenthal P. Under Utilization of Pancreas Transplants in Cystic Fibrosis Recipients in the United Network Organ Sharing (UNOS) Data 1987-2014. Am J Transplant. 2016 May; 16(5):1620-5. View in PubMed
  7. Moassesfar S, Masharani U, Frassetto LA, Szot GL, Tavakol M, Stock PG, Posselt AM. A Comparative Analysis of the Safety, Efficacy, and Cost of Islet Versus Pancreas Transplantation in Nonuremic Patients With Type 1 Diabetes. Am J Transplant. 2016 Feb; 16(2):518-26. View in PubMed
  8. Schafer AL, Weaver CM, Black DM, Wheeler AL, Chang H, Szefc GV, Stewart L, Rogers SJ, Carter JT, Posselt AM, Shoback DM, Sellmeyer DE. Intestinal Calcium Absorption Decreases Dramatically After Gastric Bypass Surgery Despite Optimization of Vitamin D Status. J Bone Miner Res. 2015 Aug; 30(8):1377-85. View in PubMed
  9. Tai DS, Shen N, Szot GL, Posselt A, Feduska NJ, Habashy A, Clerkin B, Core E, Busuttil RW, Hines OJ, Reber HA, Lipshutz GS. Autologous islet transplantation with remote islet isolation after pancreas resection for chronic pancreatitis. JAMA Surg. 2015 Feb; 150(2):118-24. View in PubMed
  10. Schafer AL, Li X, Schwartz AV, Tufts LS, Wheeler AL, Grunfeld C, Stewart L, Rogers SJ, Carter JT, Posselt AM, Black DM, Shoback DM. Changes in vertebral bone marrow fat and bone mass after gastric bypass surgery: A pilot study. Bone. 2015 May; 74:140-5. View in PubMed
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  • Lorelei Batty

    A Complex Procedure for Life-Threatening Pancreatitis

    A Complex Procedure for Life-Threatening Pancreatitis One morning in December 2014, Lorelei Batty woke up screaming in pain and sick to her stomach. Emergency room doctors in her hometown of Santa Maria, Calif., thought the 3-year-old had the flu and sent her home. But Lorelei didn't improve over the next week and a half, and a far more serious diagnosis soon came in: pancreatitis, an inflammation of the pancreas that's rare in children and can be difficult to treat. After spending most of the next nine months in seven different hospitals with deteriorating health, Lorelei finally[...]
    Story Categories: Islet Transplant
  • Mike Schofield

    Two-Time Transplant Recipient Meets Donor's Family

    Michael Schofield
    After Michael Schofield had his first islet cell transplant in April 2012, he wrote a letter thanking the family of his donor. It was over a year before he heard back from the donor’s mother. That's when he learned they had more in common than the young man whose cells Michael was carrying. He was en route to meet the mother last June, when he got another exciting piece of news: UCSF had a donor for the second islet transplant that he needed. In the space of a week he connected with one donor's family and started a new connection with another.[...]
    Story Categories: Islet TransplantType 1 Diabetes
  • Susie Rember

    Insulin-Free Patient Grateful for Islet Transplant

    Susie Rember
    Susan Rember was eight years old when she was diagnosed with type 1 diabetes in 1957. At the time, diabetics used glass syringes, tested their urine for sugar levels and were told they could never live a normal life. But Rember was mostly free from major complications for 50 years, until she suffered a heart attack in 2005. She had a quintuple by-pass, but when three of the grafted vessels immediately failed, the Denver-based artist began exploring the possibility of an islet transplant. In 2007, she got new islets through a clinical study[...]
    Story Categories: Islet TransplantType 1 Diabetes
  • Sandy Raffi-Rashed

    Surgery Ends Decades of Obesity, New Life Begins

    Sandy Raffi-Rashed after losing 185 pounds
    Sandy Raffi-Rashed after losing 185 poundsWhen Sandy Raffi-Rashed, a 60-year-old mother of two, went to the airport to pick up her youngest son visiting from Manhatten, he didn't recognize her. "I was waving to him from the car and he thought, 'Who is that strange woman waving at me?" says Raffi-Rashed, of Novato, Calif. "Then, when he saw me, he said, 'Oh my God!'" His mother had undergone a transformation after weight-loss surgery. In July of 2011, Raffi-Rashed had gastric bypass surgery at the Bariatric Surgery Center at UCSF Medical[...]
    Story Categories: Laparoscopic Gastric BypassObesityPost-Bariatric Body Contouring
  • Kim Mendes

    Insulin Free for the First Time in 40 Years

    Kim Mendes
    Bay Area native Kim Mendes has lived most of her life with Type 1 diabetes and the disease has taken a heavy toll on her body, causing a host of medical problems including peripheral neuropathy, heart disease, kidney disease and a compromised immune system. She got an islet transplant in 2010 and has been insulin free ever since. How long have you had diabetes? This is my 40th year as a Type 1 diabetic. I was seven years old when I was diagnosed. I had fallen into a diabetic coma and insulin brought me out. From that moment on I was[...]
    Story Categories: Islet TransplantType 1 Diabetes
  • Ivan Barriga

    Islet Transplant Frees Patient of Diabetes

    One afternoon, Ivan Barriga woke up in his car on the side of the road with no memory of how he ended up there. Luckily, he was not injured, but his severe case of type 1 diabetes put him at risk for passing out again without warning. "I was constantly frustrated and fearful of the next insulin reaction because it was a life and death situation," says Barriga, who at 18-years-old was diagnosed with type 1 diabetes, a condition in which the insulin-producing cells in the pancreas stop making enough insulin, a hormone needed to convert sugar[...]
    Story Categories: Islet TransplantType 1 Diabetes

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