Department of Surgery »  Faculty »  General Surgery »  Robert C. Mackersie, M.D.
 
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Department of Surgery »  Faculty »  General Surgery »  Robert C. Mackersie, M.D.

Robert C. Mackersie, M.D.

Professor of Surgery
Division of General Surgery
Director, Trauma Service,
San Francisco General Hospital
Vice Chief of Surgery, San Francisco General Hospital

Contact Information

Campus Box 0807
Department of Surgery
San Francisco General Hospital
San Francisco, CA 94143-0807
(415) 206-8673 Appointments
(415) 206-4622 Office
(415) 206-5484 Fax
rmackersie@sfghsurg.ucsf.edu

Education

  • UC Berkeley, B.S., Mechanical Engineering, 1973
  • UC Berkeley, M.S., Engineering Science, 1974
  • Michigan State University, M.D., 1978

Residencies

  • 1978-81, UCSF School of Medicine, Resident, Surgery
  • 1983-84, UCSF School of Medicine, Senior Resident, Surgery
  • 1983-85, UCSF School of Medicine, Chief Resident, Surgery

Fellowships

  • 1981-83, UCSF School of Medicine, Fellow, Trauma Research (NIH sponsored)

Postdoctoral Training

Board Certification

  • American Board of Surgery, 1986
  • American Board of Surgery, Surgical Critical Care, 1988

Program Affiliations

Clinical Expertise

  • General Surgery
  • Surgical Critical Care
  • Trauma Surgery
  • Vascular Surgery

Research Interests

  • Ventilatory management of patients with ARDS
  • Violence Prevention
  • Inflammatory lung injury following major injury
  • Trauma systems development

Biography

Mackersie is a Board certified general surgeon with board certification in surgical critical care with a regular, sustained practice in general and trauma surgery, which includes vascular and thoracic surgery. In addition, he is a regular attending on the Surgical Critical Care Service at San Francisco General Hospital and serves as the Vice-Chief of Surgery at San Francisco General Hospital.

Dr. Mackersie is a graduate of UC Berkeley and Michigan State University Medical School. He completed his internship, residency and chief residency training in general surgery and surgical critical care at the University of California, San Francisco, where he continued his specialty training and completed a trauma research fellowship. Dr. Mackersie joined the faculty at the University of California, San Diego University Hospital from 1985-1991.

Dr. Mackersie was appointed the Trauma Medical Director in 1992 at the University of California/San Francisco General Hospital and has been instrumental in expanding the multidisciplinary activities related to the Trauma Program. Dr. Mackersie currently serves as an officer for several surgical organizations and is a Governor of the American College of Surgeons. Dr. Mackersie has been appointed Secretary/Treasurer for the American Association for the Surgery of Trauma. Dr. Mackersie has also expanded the Trauma Nurse Practitioner program, and has progressed in developing the first aero-medical transport facility at San Francisco General Hospital. He has also been appointed Commissioner for the State of California Emergency Medical Services Authority, which is appointed by the Governor/California Speaker of the House.

Dr. Mackersie continues to direct the national program in Trauma System Planning and Evaluation for the American College of Surgeons, which includes the development of national benchmarks for trauma systems and trauma centers, and the creation of national guidelines for trauma systems development.

Research Summary

  • Inflammatory Lung Injury following major injury: One of the main areas of focus has been post-traumatic inflammatory lung injury. This collaborative research effort has continued, with new reports of the clinical syndrome of ARDS (ref # 63), the impact of ARDS on specific outcomes (ref # 62), and a recent report examining surrogate serum markers predictive of inflammatory lung injury. (ref # 65). The most recent work, still in preparation (Abstract, WIP ref # 3), attemps to link elements of inflammation with post-traumatic coagulopathy, and to better define the nature of early coagulopathy (pre-massive transfusion) that follows shock, traumatic brain injury, and major organ injury.
  • Ventilatory management of patients with ARDS (refs # 66,67). Technical clinical studies performed in ICU patients with ARDS that attempt to expand our understanding of "optimal" modes of lung protective ventilation (LPV) in the setting or acute lung injury. LPV strategies are one of the few, if not the only demonstrable intervention having an impact on the outcome from ARDS over the past 15 years.
  • Violence prevention recidivism (Abstracts/WIP ref # 1). Work in progress, this is part of an ongoing clinical and programmatic study that screens victims of youth violence & assesses the likelihood of recidivism. "High risk" patients are then referred into a program linking hospital services with post-discharge neighborhood/community services for violence prevention. A randomized study is being designed to compare recidivism outcomes with and without programmatic influence.

Selected Publications

  1. Dicker RA, Morabito D, Pittet JF, Campbell AC, Mackersie RC. ARDS criteria in trauma patients. Why the definitions don't work. J Trauma 2004 Sep;57(3):522-6.
  2. Ball J, Briggs S, Cooper A, Cooper G, Dawson D, Esposito T, Fendya D, Hotz H, Hunt R, Kaufmann C, Krohmer J, Mackersie RC, et al. Model trauma system planning & evaluation document. Federal Guidelines for National Trauma System Development. U.S. Department of Health & Human Services, 2006.
  3. Brohi K, Cohen MJ, Ganter MT, Parekh J, Matthay MA, Mackersie RC, Pittet JF. Pathogenic and prognostic significance of thrombomodulin and protein C in acute traumatic coagulopathy. Ann Surg 2007;May, 245:812-8.
  4. Pittet JF, Mackersie RC, Martin TR, Matthay MM. Biological markers of acute lung injury: Prognostic and pathogenetic significance. Am J Resp Crit Care Med 1997;155:1187-1205.
  5. Holland MC, Mackersie RC, Morabito D, Campbell AR, Kivett VA, Patel R, Erickson VR, Pittet JF. The development of acute lung injury is associated with worse neurologic outcome in patients with severe traumatic injury. J Trauma 2003;Jul;55(1):106-11.

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