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Madhulika Varma, M.D.

Professor of Surgery
Division of General Surgery
Chief, Section of Colorectal Surgery 
Maurice Galante, MD Distinguished Professor in Surgical Oncology
Director, UCSF Center for Pelvic Physiology 

Contact Information

(415) 885-3606 Patients & Clinic
madhulika.varma@ucsf.edu
  • 1983-87 Brown University, Providence, RI - A.B., Human Biology
  • 1987-91 Brown University, Providence, RI - M.D.
  • 1991-97 University of California, San Francisco - Resident, Surgery
  • 1997-98 University of California, San Francisco - Chief Resident, Surgery
  • 1994-96 University of California, San Francisco - Research Fellowship, Department of Stomatology, PI
  • 1999-00 University of Minnesota, Minneapolis, MN - Fellow, Colon and Rectal Surgery
  • 2000-01 University of California, San Francisco - Fellow, Advanced Training in Clinical Research: Biostatistics & Epidemiology
  • American Board of Surgery, 1999; Recertification, 2007
  • American Board of Colon and Rectal Surgery, 2001
  • Director, UCSF Center for Pelvic Physiology
  • Program Director, UCSF Center for Colorectal Surgery

Dr. Madhulika Varma is the Chief of Colorectal Surgery and an Associate Professor of Surgery at the University of California, San Francisco. She specializes in the surgical treatment of diseases of the colon, rectum and anus. Her areas of expertise include colon and rectal cancer, inflammatory bowel diseases such as ulcerative colitis, Crohn's disease and pelvic floor disorders. She is also a specialist in advanced laparoscopic and robotic colorectal surgery, using minimally invasive techniques to treat many of these diseases. Dr. Varma is also the Director of the UCSF Center for Pelvic Physiology, which evaluates patients with fecal incontinence, constipation, pelvic floor prolapse, rectal cancer and anal fistulas. She is a member of the clinical team of the UCSF Women's Continence Center and the UCSF Center for Colitis and Crohn's Disease.

Dr. Varma earned her medical degree at Brown University School of Medicine in Providence, R.I. She completed her residency in general surgery at UCSF and spent a year at the University of Minnesota to obtain specialized training in colon and rectal surgery. She returned to the faculty at UCSF in 2000, where she completed a fellowship in Clinical Outcomes Research and Epidemiology. Her research interests include the assessment of clinical outcomes and quality of life for patients with colorectal cancer, inflammatory bowel diseases, and defecation disorders. Highly respected by her peers, Dr. Varma was named to the list of U.S. News "America's Top Doctors," a distinction reserved for the top 1% of physicians in the nation for a given specialty.

  • A Randomized, Subject and Evaluator Blinded, Sham Controlled, Multicenter Study to Evaluate Efficacy and Safety of NASHA/Dx for the Treatment of Fecal Incontinence
  • The Comprehensive Validation of the CSI (Constipation Severity Instrument) and CRQOL (Constipation-Related Quality of Life) and the Comprehensive Validation of the RCM (Rome III Constipation Module)
  • A Phase II Trial of Neoadjuvant Chemoradiation and Local Excision for uT2uN0 Rectal Cancer
  • Timing of Rectal Cancer Response to Chemoradiation
  • The Effect of Rectal Resection on Bowel, Bladder, and Sexual Functioning in Patients with Inflammatory Bowel Disease
  • A Randomized Control Trial to Examine the Efficacy of Anorectal Biofeedback
  • Prevalence of Sexual Dysfunction in Ulcerative Colitis Patients
  • Outcomes of Patients Presenting to the UCSF Center for Pelvic Physiology with Pelvic Floor Disorders
 
  1. Cohan JN, Bacchetti P, Varma MG, Finlayson E. Impact of Patient Age on Procedure Type for Ulcerative Colitis: A National Study. Dis Colon Rectum. 2015 Aug; 58(8):769-74. View in PubMed
  2. Sbitany H, Kwon E, Chern H, Finlayson E, Varma MG, Hansen SL. Outcomes Analysis of Biologic Mesh Use for Abdominal Wall Reconstruction in Clean-Contaminated and Contaminated Ventral Hernia Repair. Ann Plast Surg. 2015 Aug; 75(2):201-4. View in PubMed
  3. Cohan JN, Bacchetti P, Varma MG, Finlayson E. Outcomes after ileoanal pouch surgery in frail and older adults. J Surg Res. 2015 Apr 8. View in PubMed
  4. Cohan JN, Lee PR, Chou AB, Varma MG. Faecal incontinence in men referred for specialty care: a cross-sectional study. Colorectal Dis. 2015 Mar 11. View in PubMed
  5. Wang ED, Conkling N, Xu X, Chern H, Finlayson E, Varma MG, Hansen SL, Foster RD, Hoffman WY, Sbitany H. Perineal Flap Reconstruction following Oncologic Anorectal Extirpation: An Outcomes Assessment. Plast Reconstr Surg. 2015 Jan; 135(1):176e-84e. View in PubMed
  6. Cohan JN, Varma MG. Simple interventions for complex complications: moving surgery forward. Dis Colon Rectum. 2014 Jan; 57(1):3-4. View in PubMed
  7. Finlayson E, Zhao S, Varma MG. Outcomes after rectal cancer surgery in elderly nursing home residents. Dis Colon Rectum. 2012 Dec; 55(12):1229-35. View in PubMed
  8. Wang JY, Terdiman JP, Vittinghoff E, Minichiello T, Varma MG. Hospitalized ulcerative colitis patients have an elevated risk of thromboembolic events. World J Gastroenterol. 2009 Feb 28; 15(8):927-35. View in PubMed
  9. Mathy C, Schneider K, Chen YY, Varma M, Terdiman JP, Mahadevan U. Gross versus microscopic pancolitis and the occurrence of neoplasia in ulcerative colitis. Inflamm Bowel Dis. 2003 Nov; 9(6):351-5. View in PubMed
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