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Department of Surgery »  Faculty »  Anthony Azakie, M.D., C.M.

Anthony Azakie, M.D., C.M.

Associate Professor of Surgery and Pediatrics

Chief, Division of Pediatric Cardiorthoacic Surgery

Surgical Director, UCSF Pediatric Heart Center

Surgical Director, Adult Congential Heart Program

Director, Pediatric Cardiothoracic Surgery Research Labs

Contact Information

(415) 476-3501: Phone

(415) 476-9678: Fax

azakiet@surgery.ucsf.edu

Education

  • 1984-87, McGill University B.S., Physiology
  • 1987-91, McGill University M.D.,C.M., Faculty of Medicine

Residencies

  • 1991-93, UCSF, Intern, Surgery
  • 1995-97, UCSF, Senior Resident, Surgery
  • 1997-98, UCSF, Chief Resident, Surgery
  • 1998, University of Toronto, St. Michael's Hospital, Senior Resident, Adult Cardiac Surgery
  • 1999, University of Toronto, Toronto General Hospital, Chief Resident, Adult Cardiac Surgery
  • 1999-00, University of Toronto, Toronto General Hospital, Senior Resident, Thoracic Surgery
  • 2000, University of Toronto, Hospital for Sick Children & Toronto General Hospital, Chief Resident, Congenital Heart Surgery

Fellowships

  • 2001-02, UCSF, Fellow, Pediatric Cardiac Surgery
  • 2001, University of Toronto, Hospital for Sick Children & Toronto General Hospital, Fellow, Congenital Heart Surgery

Postdoctoral Training

  • 1993-95, UCSF, Cardiovascular Research Institute, Postdoctoral Fellow, Cardiovascular Disease (Cardiology)

Board Certification

  • American Board of Surgery, 1998
  • Royal College of Physicians and Surgeons of Canada in Cardiac Surgery, 2001

Program Affiliations

  • UCSF Pediatric Heart Center
  • UCSF Fetal Treatment Center
  • Associate Professor of Surgery and Pediatrics, UC Davis

Clinical Expertise

  • Fetal, Pediatric and Adult Congential  Heart surgery
  • Complex neonatal and infant cardiac reconstructive surgery
  • Norwood procedure for hypoplastic left heart syndrome
  • Arterial switch for transposition of the great artieries
  • Single ventricle palliation
  • Extracorporeal Membrane Oxygenation (ECMO)
  • Ventricular Assist Devices (VAD)
  • ExtraCorporeal Life Support (ECLS)
  • Minimally invasive/minimal access pediatric cardiac surgery
  • Off-pump cardiac surgery
  • Complex mitral and tricuspid valve repair
  • Aortic root surgery
  • Marfans
  • Tetralogy of Fallot syndrome
  • Ross operations
  • Congenital mitral disease
  • Obstructive cardiomyopathy

Research Interests

  • Molecular regulation of cardiac differentiation
  • Perinatal Pulmonary Hypertension: Developmental Mediators

Website LInks

Biography

Dr. Anthony Azakie is Chief of Pediatric Cardiac Surgery at the University of California San Francisco and Surgical Director of the Pediatric Heart Center.  He specializes in all complex neonatal and pediatric cardiac surgery treating a variety of congenital heart defects including hypoplastic left heart syndrome, tetralogy of Fallot, transposition of the great arteries, atrioventricular septal defects, diseases of the pulmonary veins, single ventricle lesions and aortic arch problems.  He also specializes in surgery for adults with treated and untreated congenital heart defects.  Dr. Azakie works in close collaboration with other branches of the Pediatric Heart Center including the echocardiography service, catheterization lab, electrophysiology program, and pediatric cardiac intensive care unit to provide comprehensive cardiac care.  

 Dr. Azakie attended medical school at McGill University where he ranked in the top 5% and was awarded the Stewart Prize for most qualified graduating student as well as the Wood Gold Medal for most outstanding clinical performance.   Dr. Azakie first came to UCSF to complete his residency in General Surgery.   He continued his residency in Adult Cardiac Surgery and Thoracic Surgery at the University of Toronto, Toronto General Hospital and St. Michael’s Hospital.   Dr. Azakie trained as Chief Resident and Fellow in Congenital Heart Surgery through the University of Toronto at the Toronto General Hospital and Hospital for Sick Children.   Dr. Azakie returned to UCSF in 2001 as a Clinical Instructor in Pediatric Cardiac Surgery and he is currently Associate Professor of Surgery and Pediatrics at UCSF and UC Davis.  

Dr. Azakie is Director of the UCSF Pediatric Cardiothoracic Surgical Laboratories.  His research focuses on identifying mechanisms for the formation of myocardium and characterizing clinically relevant maladaptive responses of cardiac muscle.   Dr. Azakie has given invited presentations worldwide and has authored over 50 peer-reviewed publications.

Selected Publications

  1. Azakie A, Larkin SB, Farrance IK, Grenningloh G, Ordahl CP. DTEF-1, a novel member of the transcription enhancer factor-1 (TEF-1) multigene family. J Biol Chem. 217: 8260-5, 4/1/1996.
  2. Azakie A, Russell JL, McCrindle BW, Van Arsdell GS, Benson LN, Coles JG, Williams WG. Anatomic repair of anomalous left coronary artery from the pulmonary artery by aortic reimplantation: early survival, patterns of ventricular recovery and late outcome. Ann Thorac Surg. 75: 1535-41, 5/1/2003.
  3. Azakie A, Martinez D, Sapru A, Fineman J, Teitel D, Karl TR. Impact of right ventricle to pulmonary artery conduit on outcome of the modified Norwood procedure. Ann Thorac Surg. 77: 1727-33, 5/1/2004.
  4. Azakie A, Muse J, Gardner M, Skidmore KL, Miller SP, Karl TR, McQuillen PS. Cerebral oxygen balance is impaired during repair of aortic coarctation in infants and children. J Thorac Cardiovasc Surg. 130: 830-6, 9/1/2005.
  5. Azakie A, Lamont L, Fineman JR, He Y. Divergent transcriptional enhancer factor-1 (DTEF-1) regulates the cardiac troponin promoter. Am J Physiol Cell Physiol. 289: C1522-34, 12/1/2005.

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