Department of Surgery »  Faculty »  Adult Cardiothoracic Surgery »  Mark Ratcliffe, M.D.

Mark Ratcliffe, M.D.

Professor of Surgery
Division of Adult Cardiothoracic Surgery, UCSF
Co-Director, Cardiac Biomechanics Lab

Contact Information

4150 Clement Street
San Francisco, CA  94121
Tel: 415-750-2057
Fax: 415-750-2181
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  • M.D.-Case Western Reserve University, Cleveland, OH
  • B.A. - Denison University, Granville, OH
  • Internship - John Hopkins Hospital, Baltimore, MD
  • Residency - John Hopkins Hospital, Baltimore, MD
  • Residency - University of Pennsylvania Hospital, Philadelphia, PA
  • Research Fellow - University of Pennsylvania Hospital, Philadelphia, PA
  • Fellowship - University of Pennsylvania Hospital, Philadelphia, PA
  • American Board of Surgery, 1989
  • American Board of Thoracic Surgery, 1993
  • Minimally invasive cardiac surgery
  • Off-pump coronary artery bypass surgery
  • Robotic surgery
  • Surgery for heart failure
  • Thoracic aortic surgery
  • Valve repair and replacement
  • Finite element analysis of failing left ventricle

Dr. Ratcliffe received his M.D. degree from Case Western Reserve School of Medicine and completed his General Surgery and Cardiothoracic residencies at the Univeristy of Pennsylvania. Dr. Ratcliffe is certified by the American Board of Surgery and American Board of Thoracic Surgery. His special interest is in the application of finite element analysis or the failing left ventricle. Dr. Ratcliffe has been on the faculty since 1993. Currently, he is Director of the Cardiac Biomechanics Laboratory.

Dr. Ratcliffe is an active member of the American Society for Artificial Internal Organs, American Heart Association, Society of Thoracic Surgeons, Western Thoracic Surgical Association, San Francisco Surgical Society, American Association of Thoracic Surgery, and is a Fellow of the American College of Surgeons.

Most recent publications from a total of 96
  1. Ge L, Wu Y, Soleimani M, Khazalpour M, Takaba K, Zhang Z, Acevedo-Bolton G, Saloner DA, Wallace AW, Mishra R, Grossi EA, Guccione JM, Ratcliffe MB Moderate Ischemic Mitral Regurgitation after Postero-Lateral Myocardial Infarction in Sheep Alters Left Ventricular Shear but Not Normal Strain in the Infarct and Infarct Borderzone. Annals of Thoracic Surgery. 2016. View in PubMed
  2. Morgan AE, Pantoja JL, Weinsaft J, Grossi E, Guccione J, Ge L, Ratcliffe MB Finite Element Modeling of Mitral Valve Repair. J Biomech Eng. 2015 Dec 3. View in PubMed
  3. Goyal P, Kim J, Feher A, Ma CL, Gurevich S, Veal DR, Szulc M, Wong FJ, Ratcliffe MB, Levine RA, Devereux RB, Weinsaft JW Myocardial perfusion pattern for stratification of ischemic mitral regurgitation response to percutaneous coronary intervention. Coron Artery Dis. 2015 Dec; 26(8):642-50. View in PubMed
  4. Pantoja JL, Zhang Z, Tartibi M, Sun K, Macmillan W, Guccione JM, Ge L, Ratcliffe MB Residual Stress Impairs Pump Function After Surgical Ventricular Remodeling: A Finite Element Analysis. Ann Thorac Surg. 2015 Sep 1. View in PubMed
  5. Yaffee DW, Grossi EA, Ratcliffe MB Progressive design concepts in off-pump left ventricular remodeling mitral valve repair devices. Ann Cardiothorac Surg. 2015 Jul; 4(4):352-4. View in PubMed
  6. Ratcliffe M, Cambronero N, Takaba K, Ge L Studies on postinfarct left ventricular remodeling: state of the art. Ann Thorac Surg. 2015 Mar; 99(3):755-6. View in PubMed
  7. Morrel WG, Ge L, Zhang Z, Grossi EA, Guccione JM, Ratcliffe MB Effect of mitral annuloplasty device shape and size on leaflet and myofiber stress following repair of posterior leaflet prolapse: a patient-specific finite element simulation. J Heart Valve Dis. 2014 Nov; 23(6):727-34. View in PubMed
  8. Lovett DH, Chu C, Wang G, Ratcliffe MB, Baker AJ A N-terminal truncated intracellular isoform of matrix metalloproteinase-2 impairs contractility of mouse myocardium. Front Physiol. 2014; 5:363. View in PubMed
  9. Shimkunas R, Makwana O, Spaulding K, Bazargan M, Khazalpour M, Takaba K, Soleimani M, Myagmar BE, Lovett DH, Simpson PC, Ratcliffe MB, Baker AJ Myofilament dysfunction contributes to impaired myocardial contraction in the infarct border zone. Am J Physiol Heart Circ Physiol. 2014 Oct 15; 307(8):H1150-8. View in PubMed
  10. Pantoja JL, Ge L, Zhang Z, Morrel WG, Guccione JM, Grossi EA, Ratcliffe MB Posterior papillary muscle anchoring affects remote myofiber stress and pump function: finite element analysis. Ann Thorac Surg. 2014 Oct; 98(4):1355-62. View in PubMed
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