Mark Ratcliffe, M.D.

Professor of Surgery
Division of Adult Cardiothoracic Surgery, UCSF
Co-Director, Cardiac Biomechanics Lab

Contact Information

4150 Clement Street
San Francisco, CA  94121
Tel: 415-750-2057
Fax: 415-750-2181
  • M.D.-Case Western Reserve University, Cleveland, OH
  • B.A. - Denison University, Granville, OH
  • Internship - John Hopkins Hospital, Baltimore, MD
  • Residency - John Hopkins Hospital, Baltimore, MD
  • Residency - University of Pennsylvania Hospital, Philadelphia, PA
  • Research Fellow - University of Pennsylvania Hospital, Philadelphia, PA
  • Fellowship - University of Pennsylvania Hospital, Philadelphia, PA
  • American Board of Surgery, 1989
  • American Board of Thoracic Surgery, 1993
  • Minimally invasive cardiac surgery
  • Off-pump coronary artery bypass surgery
  • Robotic surgery
  • Surgery for heart failure
  • Thoracic aortic surgery
  • Valve repair and replacement
  • Finite element analysis of failing left ventricle

Dr. Ratcliffe received his M.D. degree from Case Western Reserve School of Medicine and completed his General Surgery and Cardiothoracic residencies at the Univeristy of Pennsylvania. Dr. Ratcliffe is certified by the American Board of Surgery and American Board of Thoracic Surgery. His special interest is in the application of finite element analysis or the failing left ventricle. Dr. Ratcliffe has been on the faculty since 1993. Currently, he is Director of the Cardiac Biomechanics Laboratory.

Dr. Ratcliffe is an active member of the American Society for Artificial Internal Organs, American Heart Association, Society of Thoracic Surgeons, Western Thoracic Surgical Association, San Francisco Surgical Society, American Association of Thoracic Surgery, and is a Fellow of the American College of Surgeons.

Most recent publications from a total of 91
  1. Ratcliffe M, Cambronero N, Takaba K, Ge L. Studies on postinfarct left ventricular remodeling: state of the art. Ann Thorac Surg. 2015 Mar; 99(3):755-6. View in PubMed
  2. Morrel WG, Ge L, Zhang Z, Grossi EA, Guccione JM, Ratcliffe MB. Effect of mitral annuloplasty device shape and size on leaflet and myofiber stress following repair of posterior leaflet prolapse: a patient-specific finite element simulation. J Heart Valve Dis. 2014 Nov; 23(6):727-34. View in PubMed
  3. Lovett DH, Chu C, Wang G, Ratcliffe MB, Baker AJ. A N-terminal truncated intracellular isoform of matrix metalloproteinase-2 impairs contractility of mouse myocardium. Front Physiol. 2014; 5:363. View in PubMed
  4. Shimkunas R, Makwana O, Spaulding K, Bazargan M, Khazalpour M, Takaba K, Soleimani M, Myagmar BE, Lovett DH, Simpson PC, Ratcliffe MB, Baker AJ. Myofilament dysfunction contributes to impaired myocardial contraction in the infarct border zone. Am J Physiol Heart Circ Physiol. 2014 Oct 15; 307(8):H1150-8. View in PubMed
  5. Pantoja JL, Ge L, Zhang Z, Morrel WG, Guccione JM, Grossi EA, Ratcliffe MB. Posterior papillary muscle anchoring affects remote myofiber stress and pump function: finite element analysis. Ann Thorac Surg. 2014 Oct; 98(4):1355-62. View in PubMed
  6. Lee LC, Ge L, Zhang Z, Pease M, Nikolic SD, Mishra R, Ratcliffe MB, Guccione JM. Patient-specific finite element modeling of the Cardiokinetix Parachute(®) device: effects on left ventricular wall stress and function. Med Biol Eng Comput. 2014 Jun; 52(6):557-66. View in PubMed
  7. Ratcliffe M, Cambronero N, Long S. Invited commentary. Ann Thorac Surg. 2014 May; 97(5):1524-5. View in PubMed
  8. Lee LC, Genet M, Dang AB, Ge L, Guccione JM, Ratcliffe MB. Applications of computational modeling in cardiac surgery. J Card Surg. 2014 May; 29(3):293-302. View in PubMed
  9. Ge L, Morrel WG, Ward A, Mishra R, Zhang Z, Guccione JM, Grossi EA, Ratcliffe MB. Measurement of mitral leaflet and annular geometry and stress after repair of posterior leaflet prolapse: virtual repair using a patient-specific finite element simulation. Ann Thorac Surg. 2014 May; 97(5):1496-503. View in PubMed
  10. Ratcliffe MB, Wozniak CJ. Invited commentary. Ann Thorac Surg. 2014 Mar; 97(3):907-8. View in PubMed
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