M.D.-Case Western Reserve University, Cleveland, OH
B.A. - Denison University, Granville, OH
Internship - John Hopkins Hospital, Baltimore, MD
Residency - John Hopkins Hospital, Baltimore, MD
Residency - University of Pennsylvania Hospital, Philadelphia, PA
Research Fellow - University of Pennsylvania Hospital, Philadelphia, PA
Fellowship - University of Pennsylvania Hospital, Philadelphia, PA
American Board of Surgery, 1989
American Board of Thoracic Surgery, 1993
Minimally invasive cardiac surgery
Off-pump coronary artery bypass surgery
Surgery for heart failure
Thoracic aortic surgery
Valve repair and replacement
Finite element analysis of failing left ventricle
Dr. Ratcliffe received his M.D. degree from Case Western Reserve School of Medicine and completed his General Surgery and Cardiothoracic residencies at the Univeristy of Pennsylvania. Dr. Ratcliffe is certified by the American Board of Surgery and American Board of Thoracic Surgery. His special interest is in the application of finite element analysis or the failing left ventricle. Dr. Ratcliffe has been on the faculty since 1993. Currently, he is Director of the Cardiac Biomechanics Laboratory.
Dr. Ratcliffe is an active member of the American Society for Artificial Internal Organs, American Heart Association, Society of Thoracic Surgeons, Western Thoracic Surgical Association, San Francisco Surgical Society, American Association of Thoracic Surgery, and is a Fellow of the American College of Surgeons.
Most recent publications from a total of 97
Ge L, Wu Y, Soleimani M, Khazalpour M, Takaba K, Tartibi M, Zhang Z, Acevedo-Bolton G, Saloner DA, Wallace AW, Mishra R, Grossi EA, Guccione JM, Ratcliffe MB. Moderate Ischemic Mitral Regurgitation After Posterolateral Myocardial Infarction in Sheep Alters Left Ventricular Shear but Not Normal Strain in the Infarct and Infarct Borderzone. Ann Thorac Surg. 2016 May; 101(5):1691-9. View in PubMed
Morgan AE, Pantoja JL, Weinsaft J, Grossi E, Guccione JM, Ge L, Ratcliffe M. Finite Element Modeling of Mitral Valve Repair. J Biomech Eng. 2016 Feb 1; 138(2). View in PubMed
Goyal P, Kim J, Feher A, Ma CL, Gurevich S, Veal DR, Szulc M, Wong FJ, Ratcliffe MB, Levine RA, Devereux RB, Weinsaft JW. Myocardial perfusion pattern for stratification of ischemic mitral regurgitation response to percutaneous coronary intervention. Coron Artery Dis. 2015 Dec; 26(8):642-50. View in PubMed
Cambronero N, Ratcliffe M, Ge L. Patient Specific Finite Element Modeling of the Failing Heart.
How Computational Mathematical Modeling Can Direct Optimum Surgical Procedures in Children.
Biomedical Engineering Society Annual Meeting. Tampa, Florida. 2015. View in PubMed
Pantoja JL, Zhang Z, Tartibi M, Sun K, Macmillan W, Guccione JM, Ge L, Ratcliffe MB. Residual Stress Impairs Pump Function After Surgical Ventricular Remodeling: A Finite Element Analysis. Ann Thorac Surg. 2015 Dec; 100(6):2198-205. View in PubMed
Yaffee DW, Grossi EA, Ratcliffe MB. Progressive design concepts in off-pump left ventricular remodeling mitral valve repair devices. Ann Cardiothorac Surg. 2015 Jul; 4(4):352-4. View in PubMed
Ratcliffe M, Cambronero N, Takaba K, Ge L. Studies on postinfarct left ventricular remodeling: state of the art. Ann Thorac Surg. 2015 Mar; 99(3):755-6. View in PubMed
Morrel WG, Ge L, Zhang Z, Grossi EA, Guccione JM, Ratcliffe MB. Effect of mitral annuloplasty device shape and size on leaflet and myofiber stress following repair of posterior leaflet prolapse: a patient-specific finite element simulation. J Heart Valve Dis. 2014 Nov; 23(6):727-34. View in PubMed
Lovett DH, Chu C, Wang G, Ratcliffe MB, Baker AJ. A N-terminal truncated intracellular isoform of matrix metalloproteinase-2 impairs contractility of mouse myocardium. Front Physiol. 2014; 5:363. View in PubMed
Shimkunas R, Makwana O, Spaulding K, Bazargan M, Khazalpour M, Takaba K, Soleimani M, Myagmar BE, Lovett DH, Simpson PC, Ratcliffe MB, Baker AJ. Myofilament dysfunction contributes to impaired myocardial contraction in the infarct border zone. Am J Physiol Heart Circ Physiol. 2014 Oct 15; 307(8):H1150-8. View in PubMed
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