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Legendary Surgeon Maurice Galante Dies
Maurice Galante, M.D., a legendary master surgeon at UCSF and renaissance man, died on February 5, 2013. His career is memorialized by the Maurice Galante Lecture Program and Maurice Galante Distinguished Professorship.
Julius M. Guccione, Ph.D.
Professor of Surgery
Division of Adult Cardiothoracic Surgery
Co-Director, Cardiac Biomechanics Lab
Contact Information
San Francisco, CA 94121
BiographyEducation
- 1985, Tulane University, New Orleans, BS
- 1985-1987, University of California, San Diego, MS
- 1985-1990, University of California, San Diego, PhD
Research Interests
- Stem cell transplantation on the biophysics of cardiac function
Biography
Dr. Guccione studies the role of stem cell transplantation on the biophysics of cardiac function and the use of mechanical engineering principles in the diagnosis and treatment of cardiac disease. He is Co-director of the SFVAMC Cardiac Biomechanics Laboratory, which uses a combination of mathematical modeling and animal experiments to determine the effect of cardiac surgery on left ventricular function and remodeling. He is also a Core member of the UCB/UCSF Joint Graduate Group in Bioengineering. Current projects involve testing and validating a software tool for determining myocardial material properties in-vivo from cardiac catheterization and magnetic resonance imaging, and determining the effects of three different surgical treatments on function and regional mechanics in sheep.
Selected Publications
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Zahalak, G.I., de Laborderie, V., and Guccione, J.M., "The Effects of Cross-Fiber Deformation on Axial Fiber Stress in Myocardium," ASME Journal of Biomechanical Engineering, 1999, Vol. 121, pp. 376-385
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Guccione, J.M., Moonly, S.M., Moustakidis, P., Costa, K.D., Moulton, M.J., Ratcliffe, M.B., and Pasque, M.K., "Mechanism Underlying Mechanical Dysfunction in the Border Zone of Left Ventricular Aneurysm: A Finite Element Model Study," Annals of Thoracic Surgery, 2001, Vol. 71, pp. 654-662.
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Walker, J.C., Ratcliffe, M.B., Zhang, P., Wallace, A.W., Fata, B., Hsu, E.W., Saloner, D., and Guccione, J.M., "MRI-Based Finite-Element Analysis of Left Ventricular Aneurysm," American Journal of Physiology, 2005, Vol. 289, pp. H692-H700.
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Guccione, J.M., Walker, J.C., Bietler, J.R., Moonly, S.M., Zhang, P., Guttman, M.A., Ozturk, C., McVeigh, E.R., Wallace, A.W., Saloner, D.A., and Ratcliffe, M.B., "The Effect of Anteroapical Aneurysm Plication on End-Systolic Three-Dimensional Strain in the Sheep: A Magnetic Resonance Imaging Tagging Study," Journal of Thoracic and Cardiovascular Surgery, 2006, Vol. 131, pp. 579-586.
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Wall, S.T., Walker, J.C., Healy, K.E., Ratcliffe, M.B., and Guccione, J.M., "Theoretical Impact of the Injection of Material into the Myocardium: A Finite Element Model Simulation," Circulation, 2006, Vol. 114, pp. 2627-2635.
Researchers are working
on a system that could show surgeons the results of an operation
without their ever lifting a scalpel.